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The map label for this gene is gumM [H]

Identifier: 78048332

GI number: 78048332

Start: 3154101

End: 3154895

Strand: Reverse

Name: gumM [H]

Synonym: XCV2776

Alternate gene names: 78048332

Gene position: 3154895-3154101 (Counterclockwise)

Preceding gene: 78048333

Following gene: 78048331

Centisome position: 60.92

GC content: 64.28

Gene sequence:

>795_bases
ATGATGCAGGGCCAGCGCGTGGATGTGGAAACAACGGGGATTGCCAGCGGAACCACGCCGCCGGGTGTGGTGATTCCGTT
GGGCGGCTTTCCGGTCCTGTCCACCACGCAGGAAGCCTTTGCGTTGGATCTATTCCACGCGCTGGCCGCCCGTCAGCCGC
GACGGGTGTTCTTTGCCAATACCAATTTCATCGTGCAATGCCAGGCGCTGCGGACGCGCATGCGCGAGCCCAGCGTGCGC
ATCGTCAACGACGGGATCGGCATGGATCTGGCTGCGCGGCTGATCCACGGCCGCCGCTTTGCCGGCAACCTCAATGGCAC
CGACCTGATTCCGTATCTGTGCCGTGAGAGTGCGCAACCGCTGAAATTCTTTCTGCTGGGCGGCCGTCCGGGTGTGGGCA
AGACCGCTGCGGCGACGCTGACCGGGACCTTGGGGCAGCAGGTGGTCGGCATGTGCGATGGTTATGGCGAATTTGCGGCG
GCGGGCGAGGGCCTGGCCGAGCGCATCAATCGCTCCGGTGCCGATGTGCTGCTGGTGGCGTTCGGCAATCCGCTGCAGGA
GCGCTGGATCCTGGACCACAGCCATGCGCTGAGCGTGCCGCTGGTGTTCGGGGTGGGCGCATTGCTCGATTTCTTGTCCG
GTACCGCAAAGCGTGCGCCCGAGTGGGTGCGAGGCCTGCACATGGAGTGGATGTATCGGCTGCTCAACGAGCCACGCCGT
TTGCTCAAGCGCTATAGCTGGGATTTGTTGGTGTTCTTCCGCACCTGCTTGCGCGCGGGAAAGCAGCTGCCCTGA

Upstream 100 bases:

>100_bases
GTGGAGGAGTGTCTGCAACTGGGCGGCAACGGCGATTTCGATCTGGAAAAGCTGCAGGCCGGGCTGTTGGCTGCCTTCCC
TTACGACCTTTGGTGATTCG

Downstream 100 bases:

>100_bases
TGCAGCGCAGGCGTGTCTGGCCTAGCATGCCTGCATGCATCCGACCGCCGCCGCCCTGATCCGCTCGCTGGACCTCGCCC
CGCATCCGGAAGGCGGGCAC

Product: xanthan biosynthesis glycosyltransferase GumM

Products: C55-PP-GlcNAc-ManNAcA; UDP [C]

Alternate protein names: UDP-ManNAcA transferase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MMQGQRVDVETTGIASGTTPPGVVIPLGGFPVLSTTQEAFALDLFHALAARQPRRVFFANTNFIVQCQALRTRMREPSVR
IVNDGIGMDLAARLIHGRRFAGNLNGTDLIPYLCRESAQPLKFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAA
AGEGLAERINRSGADVLLVAFGNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRGLHMEWMYRLLNEPRR
LLKRYSWDLLVFFRTCLRAGKQLP

Sequences:

>Translated_264_residues
MMQGQRVDVETTGIASGTTPPGVVIPLGGFPVLSTTQEAFALDLFHALAARQPRRVFFANTNFIVQCQALRTRMREPSVR
IVNDGIGMDLAARLIHGRRFAGNLNGTDLIPYLCRESAQPLKFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAA
AGEGLAERINRSGADVLLVAFGNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRGLHMEWMYRLLNEPRR
LLKRYSWDLLVFFRTCLRAGKQLP
>Mature_264_residues
MMQGQRVDVETTGIASGTTPPGVVIPLGGFPVLSTTQEAFALDLFHALAARQPRRVFFANTNFIVQCQALRTRMREPSVR
IVNDGIGMDLAARLIHGRRFAGNLNGTDLIPYLCRESAQPLKFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAA
AGEGLAERINRSGADVLLVAFGNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRGLHMEWMYRLLNEPRR
LLKRYSWDLLVFFRTCLRAGKQLP

Specific function: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in ECA synthesis [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=159, Percent_Identity=34.5911949685535, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023085
- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: 2.4.1.- [C]

Molecular weight: Translated: 28948; Mature: 28948

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQGQRVDVETTGIASGTTPPGVVIPLGGFPVLSTTQEAFALDLFHALAARQPRRVFFAN
CCCCCEECEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEC
TNFIVQCQALRTRMREPSVRIVNDGIGMDLAARLIHGRRFAGNLNGTDLIPYLCRESAQP
CCEEEEEHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHCCCCCCCHHHHHHHHCCCCC
LKFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAAAGEGLAERINRSGADVLLVA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEE
FGNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRGLHMEWMYRLLNEPRR
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHH
LLKRYSWDLLVFFRTCLRAGKQLP
HHHHHCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMQGQRVDVETTGIASGTTPPGVVIPLGGFPVLSTTQEAFALDLFHALAARQPRRVFFAN
CCCCCEECEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEC
TNFIVQCQALRTRMREPSVRIVNDGIGMDLAARLIHGRRFAGNLNGTDLIPYLCRESAQP
CCEEEEEHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHCCCCCCCHHHHHHHHCCCCC
LKFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAAAGEGLAERINRSGADVLLVA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEE
FGNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRGLHMEWMYRLLNEPRR
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHH
LLKRYSWDLLVFFRTCLRAGKQLP
HHHHHCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-acetyl-D-mannosaminuronic-acid; undecaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate [C]

Specific reaction: UDP-N-acetyl-D-mannosaminuronic-acid + undecaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate = C55-PP-GlcNAc-ManNAcA + UDP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA