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The map label for this gene is fabH [H]

Identifier: 78048326

GI number: 78048326

Start: 3150068

End: 3151135

Strand: Reverse

Name: fabH [H]

Synonym: XCV2770

Alternate gene names: 78048326

Gene position: 3151135-3150068 (Counterclockwise)

Preceding gene: 78048327

Following gene: 78048325

Centisome position: 60.85

GC content: 68.82

Gene sequence:

>1068_bases
ATGCACGGCGGTGGGCCTGCCGATGCGGCCACGGTATGCTGCGCGCCTTCATGTTTCGAGAGCTCCGCGTTGAACGCATT
GCCGCTGCGCATCCTGGGCACCGGGCGCCATGTTCCGGCGACGGAAGTGACATCGCACCAGTTGGACGAGCGCTGGCAGT
TGCCGGCCGGAACCACGTTCGCGCGTCTGGGCGTGGAGACGCGCCATTACGTGGGCGAGGGCGAGACCGCATCGTCGATG
GGGGCAGCCGCTGCACAGCAGGCCTTGGCCAGCGCCGGGCTCGATGCCAGCCGGATCGATTGCCTGATCTCCGCCTGCAG
CGTCATGGAGCAGCCGATTCCCTGCCAGGCGGTGCTGATCCAGCGCGCGCTCGGCCTCGGCGATTCGGGCATCCCCGCAT
TCGACGTCAATGCAACCTGCCTCAGTTTTCTGGTGGCCCTGGACATGGCGGCCAACGCACTGGCGCTAGGTCGCTACGAG
CGCGTGCTGATCGTCTCCAGCGAAGTCGCATCGGCCGGGCTGGATGCGGCGACGCCGGCCACGGCCGGCTTGTTCGGCGA
TGGCGCAGCCGCAGTGGTCGTTGGACGCAGCGACGCAGGGCAGGGCTCGGCGCTGCTCTCCAGCCGGCTGTCCAGCTATG
GCAATGGCGCCGAGCTGTGCCGCATTCGCGGCGGTGGCACGCGTTACCCGCATGGCGAAGACAGCGCGCCCGATGCCTCG
CGCGTGTTCTGCATGGACGGACGCGGCGCCTACCGTTTCGCTGCGCGGCATCTGCCGGCGTTCTGGGAACAGCTGCTGCA
CGAGGCCGGCACCGCCACCGCAGCCTTGCGTTGCCTGGTACCGCACCAGGCTTCCGGCGGCGGCCTGGATCATGTGGTGC
AGACCTTGGGACTGCGCCCCGAACAGGTGGTGCGCATCCTGCAACACACGGGTAACCAGGTCGCCGCGTCGTTGCCGCAT
GCGCTGCATCACGCACGCGTCGACCTGGGCCTGCAGCGTGGCGATCTGGTCGCGCTGCTCGGCACCGGGGCAGGGCTTGC
CATCGGCGGCATGGTGTTGCGTTACTGA

Upstream 100 bases:

>100_bases
TGCCGAGCACGAGCACAGCAGCTGGCAGAGATGCAATGGATGCGGCAGGCGGCTGTTGCGCGGCGTGCCTCGCGGTGCAT
GCGCTTAAAGGTGTATCGGC

Downstream 100 bases:

>100_bases
TGCCGGTCCGCGTGTCGCTCGAGCTGCTGCGCGTGGGCCACTGTCGCCATTGCGAACGCATGGTGCGTGCAGATGGTCAC
TGGCATGCGGTGGAATTCCC

Product: 3-oxoacyl-[acyl-carrier protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MHGGGPADAATVCCAPSCFESSALNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTFARLGVETRHYVGEGETASSM
GAAAAQQALASAGLDASRIDCLISACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSFLVALDMAANALALGRYE
RVLIVSSEVASAGLDAATPATAGLFGDGAAAVVVGRSDAGQGSALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDAS
RVFCMDGRGAYRFAARHLPAFWEQLLHEAGTATAALRCLVPHQASGGGLDHVVQTLGLRPEQVVRILQHTGNQVAASLPH
ALHHARVDLGLQRGDLVALLGTGAGLAIGGMVLRY

Sequences:

>Translated_355_residues
MHGGGPADAATVCCAPSCFESSALNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTFARLGVETRHYVGEGETASSM
GAAAAQQALASAGLDASRIDCLISACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSFLVALDMAANALALGRYE
RVLIVSSEVASAGLDAATPATAGLFGDGAAAVVVGRSDAGQGSALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDAS
RVFCMDGRGAYRFAARHLPAFWEQLLHEAGTATAALRCLVPHQASGGGLDHVVQTLGLRPEQVVRILQHTGNQVAASLPH
ALHHARVDLGLQRGDLVALLGTGAGLAIGGMVLRY
>Mature_355_residues
MHGGGPADAATVCCAPSCFESSALNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTFARLGVETRHYVGEGETASSM
GAAAAQQALASAGLDASRIDCLISACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSFLVALDMAANALALGRYE
RVLIVSSEVASAGLDAATPATAGLFGDGAAAVVVGRSDAGQGSALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDAS
RVFCMDGRGAYRFAARHLPAFWEQLLHEAGTATAALRCLVPHQASGGGLDHVVQTLGLRPEQVVRILQHTGNQVAASLPH
ALHHARVDLGLQRGDLVALLGTGAGLAIGGMVLRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=326, Percent_Identity=30.3680981595092, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 36443; Mature: 36443

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGGGPADAATVCCAPSCFESSALNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTF
CCCCCCCCHHHEECCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHH
ARLGVETRHYVGEGETASSMGAAAAQQALASAGLDASRIDCLISACSVMEQPIPCQAVLI
HHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
QRALGLGDSGIPAFDVNATCLSFLVALDMAANALALGRYERVLIVSSEVASAGLDAATPA
HHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHCCCCCCCCC
TAGLFGDGAAAVVVGRSDAGQGSALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDAS
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCC
RVFCMDGRGAYRFAARHLPAFWEQLLHEAGTATAALRCLVPHQASGGGLDHVVQTLGLRP
EEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCCCCCCCHHHHHHHHCCCH
EQVVRILQHTGNQVAASLPHALHHARVDLGLQRGDLVALLGTGAGLAIGGMVLRY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure
MHGGGPADAATVCCAPSCFESSALNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTF
CCCCCCCCHHHEECCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHH
ARLGVETRHYVGEGETASSMGAAAAQQALASAGLDASRIDCLISACSVMEQPIPCQAVLI
HHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
QRALGLGDSGIPAFDVNATCLSFLVALDMAANALALGRYERVLIVSSEVASAGLDAATPA
HHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHCCCCCCCCC
TAGLFGDGAAAVVVGRSDAGQGSALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDAS
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCC
RVFCMDGRGAYRFAARHLPAFWEQLLHEAGTATAALRCLVPHQASGGGLDHVVQTLGLRP
EEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCCCCCCCHHHHHHHHCCCH
EQVVRILQHTGNQVAASLPHALHHARVDLGLQRGDLVALLGTGAGLAIGGMVLRY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA