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The map label for this gene is coaD [H]

Identifier: 78048265

GI number: 78048265

Start: 3068456

End: 3068962

Strand: Reverse

Name: coaD [H]

Synonym: XCV2709

Alternate gene names: 78048265

Gene position: 3068962-3068456 (Counterclockwise)

Preceding gene: 78048266

Following gene: 78048264

Centisome position: 59.26

GC content: 65.68

Gene sequence:

>507_bases
ATGAGCGTTGCCAATAGCCGCACCGCCGTCTATCCCGGTACCTTCGACCCGATCACCAATGGGCATATCGACCTGGTGAA
TCGCGCCGCGCCGTTGTTCGAGCGCGTGGTGGTGGGTGTGGCGTATAGCCCCTCCAAGGGCCCGGCATTGTCGCTGGAGC
GCCGCGTGGCGCTGGCCCAGGAAGCGCTGGCGGCGCATACCAATGTGGAAGTGCGCGGCTTCGATACCCTGCTGGCGCAT
TTCGTGCGCGAGATGGGCGCCGGCGTGCTGCTGCGCGGCCTGCGGGCAGTGTCCGACTTCGAATACGAATTCCAGATGGC
CAGCATGAACCGCCATCTGATCCCGGAGGTGGAAACGCTGTTTCTTACCCCGGCCGAGCAATACAGCTTCATCTCGTCCT
CGCTGGTGCGCGAAATCGCGCGGCTGGGCGGGGATGTGTCCGGCTTCGTGCCGGCATCGGTTGTCGAGGCCTTGCGGCAG
GTGCGCCAGTCCCGCGCGCAGGCCTGA

Upstream 100 bases:

>100_bases
GGCATCTGCACCGCGAGGGCGCCACCCGTGAGGTGCGCTATGCGCTGTACCGCCGGGCCGCTGCTACACTGAAGAGCGAT
CCGACCCCGGTAGTCTCCGT

Downstream 100 bases:

>100_bases
TCATCTGCAGTTACATCACCACATGCATTTCAAAGGGAGGAGTTTCATGAAACACACCATGCGCGCTCTGGCGCTCGCTT
CGATCGCCGCTCTGGCGGTC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALSLERRVALAQEALAAHTNVEVRGFDTLLAH
FVREMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVEALRQ
VRQSRAQA

Sequences:

>Translated_168_residues
MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALSLERRVALAQEALAAHTNVEVRGFDTLLAH
FVREMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVEALRQ
VRQSRAQA
>Mature_167_residues
SVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALSLERRVALAQEALAAHTNVEVRGFDTLLAHF
VREMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVEALRQV
RQSRAQA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=152, Percent_Identity=60.5263157894737, Blast_Score=199, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18300; Mature: 18169

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALSLERRVALAQ
CCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
EALAAHTNVEVRGFDTLLAHFVREMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETL
HHHHHHCCCEECHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHE
FLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVEALRQVRQSRAQA
EECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALSLERRVALAQ
CCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
EALAAHTNVEVRGFDTLLAHFVREMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETL
HHHHHHCCCEECHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHE
FLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVEALRQVRQSRAQA
EECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]