Click here to switch to the map view.

The map label for this gene is arsB [H]

Identifier: 78045129

GI number: 78045129

Start: 967638

End: 968714

Strand: Direct

Name: arsB [H]

Synonym: CHY_1093

Alternate gene names: 78045129

Gene position: 967638-968714 (Clockwise)

Preceding gene: 78043737

Following gene: 78043914

Centisome position: 40.29

GC content: 42.34

Gene sequence:

>1077_bases
ATGAGCCAAACTTCTGCTAAATTATCGTTTGTAGACCGGTATTTAACCGTCTGGATTTTACTGGCAATGGTTTTGGGTGT
TGCCATTGGTTATTTCTTTCCCGGGATTGCTGGGCTTTTAGACCGCTTGAGCATTGATACCACTTCCATACCCATTGCTA
TTGGCCTTATCTGGATGATGTATCCGCCGCTGGCCAAAGTGCGGTATGAAGAAGTTAATAAAATTTTCCGGGGTGGCAGC
AAAATTTTCCTATTTTCCATCCTGCAAAACTGGATTATCGGGCCGGTTTTAATGTTTATTTTGGCCTATATTTTCTTAAG
AAACTATCCCGAGTATTTCATGGGATTAGTTTTAATCGGCCTTGCCCGGTGTATCGCCATGGTTATTCTCTGGAATGCTC
TGGCCAAAGGAGACGCTGAGTATGCAGCAGCACTTGTTGCGCTAAATTCCCTCTTTCAGGTATTTTTCTACTCAACTTAT
GCTTATTTCTTTATCAAAGTGGTTCCGGGCTGGCTTGGTTATGATACCAAGGGGGTTGTCCTTGACATTTCCATGGCGGA
AATCGCTAAGAGTGTTTTTATCTACCTTGGTATTCCTTTTTTAGCCGGAGTAATTACCCGGTTTTCTCTTTTGAAATCCA
AAGGGCGGGAATGGTATGAAACAAAGTTTATCCCCAAATTAAGTCCTACCGCTTTATATGCGTTACTTTTTACCATTGTC
GTGATGTTTTCTTTAAAGGGTCAGTACATTGTGAAACTTCCGTTGGATGTGGTTAGGGTAGCTATTCCTTTAATTGCTTA
CTTTGTATTAATGTTCTTTATTTCCTTTTACATTTCGGCCAAGGCTGGTTTTGGTTATGCCCGGACCGCTACATTATCGT
TCACTGCTGCCAGTAACAATTTTGAGCTGGCGATAGCGGTGGCTGTGGCTACCTTTGGGTTAAATTCCGGGCAGGCGTTT
GCGGCGGTTATCGGTCCCCTCATTGAAGTGCCGGTTATGCTCTGGCTGGTTAACATGGCCTTAAAATTAAAAGATAAATA
TTTTGGCGAAGGTGAACAGTATTATGAGTGGTTTTAA

Upstream 100 bases:

>100_bases
TACTGGAAACTCCGGTAAAACCTTCACCCCTTCGGGAACAACCGGATTTATGCGAATTTTTAGGATTTAAAAAAGAAGTC
TGTGAGGAAGGAGAGGAGTT

Downstream 100 bases:

>100_bases
AGTCCTGCGGTTGAGGGGGAGATTGTTCTCCGTTTACCGGGGGTTCTAATAAACTCCAGTACGACGAAGGAAGGAACCAT
AACCAATGATTCTTTTATTG

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSQTSAKLSFVDRYLTVWILLAMVLGVAIGYFFPGIAGLLDRLSIDTTSIPIAIGLIWMMYPPLAKVRYEEVNKIFRGGS
KIFLFSILQNWIIGPVLMFILAYIFLRNYPEYFMGLVLIGLARCIAMVILWNALAKGDAEYAAALVALNSLFQVFFYSTY
AYFFIKVVPGWLGYDTKGVVLDISMAEIAKSVFIYLGIPFLAGVITRFSLLKSKGREWYETKFIPKLSPTALYALLFTIV
VMFSLKGQYIVKLPLDVVRVAIPLIAYFVLMFFISFYISAKAGFGYARTATLSFTAASNNFELAIAVAVATFGLNSGQAF
AAVIGPLIEVPVMLWLVNMALKLKDKYFGEGEQYYEWF

Sequences:

>Translated_358_residues
MSQTSAKLSFVDRYLTVWILLAMVLGVAIGYFFPGIAGLLDRLSIDTTSIPIAIGLIWMMYPPLAKVRYEEVNKIFRGGS
KIFLFSILQNWIIGPVLMFILAYIFLRNYPEYFMGLVLIGLARCIAMVILWNALAKGDAEYAAALVALNSLFQVFFYSTY
AYFFIKVVPGWLGYDTKGVVLDISMAEIAKSVFIYLGIPFLAGVITRFSLLKSKGREWYETKFIPKLSPTALYALLFTIV
VMFSLKGQYIVKLPLDVVRVAIPLIAYFVLMFFISFYISAKAGFGYARTATLSFTAASNNFELAIAVAVATFGLNSGQAF
AAVIGPLIEVPVMLWLVNMALKLKDKYFGEGEQYYEWF
>Mature_357_residues
SQTSAKLSFVDRYLTVWILLAMVLGVAIGYFFPGIAGLLDRLSIDTTSIPIAIGLIWMMYPPLAKVRYEEVNKIFRGGSK
IFLFSILQNWIIGPVLMFILAYIFLRNYPEYFMGLVLIGLARCIAMVILWNALAKGDAEYAAALVALNSLFQVFFYSTYA
YFFIKVVPGWLGYDTKGVVLDISMAEIAKSVFIYLGIPFLAGVITRFSLLKSKGREWYETKFIPKLSPTALYALLFTIVV
MFSLKGQYIVKLPLDVVRVAIPLIAYFVLMFFISFYISAKAGFGYARTATLSFTAASNNFELAIAVAVATFGLNSGQAFA
AVIGPLIEVPVMLWLVNMALKLKDKYFGEGEQYYEWF

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=331, Percent_Identity=35.6495468277946, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 40143; Mature: 40012

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTSAKLSFVDRYLTVWILLAMVLGVAIGYFFPGIAGLLDRLSIDTTSIPIAIGLIWMM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
YPPLAKVRYEEVNKIFRGGSKIFLFSILQNWIIGPVLMFILAYIFLRNYPEYFMGLVLIG
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LARCIAMVILWNALAKGDAEYAAALVALNSLFQVFFYSTYAYFFIKVVPGWLGYDTKGVV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCEE
LDISMAEIAKSVFIYLGIPFLAGVITRFSLLKSKGREWYETKFIPKLSPTALYALLFTIV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHH
VMFSLKGQYIVKLPLDVVRVAIPLIAYFVLMFFISFYISAKAGFGYARTATLSFTAASNN
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCC
FELAIAVAVATFGLNSGQAFAAVIGPLIEVPVMLWLVNMALKLKDKYFGEGEQYYEWF
CEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
>Mature Secondary Structure 
SQTSAKLSFVDRYLTVWILLAMVLGVAIGYFFPGIAGLLDRLSIDTTSIPIAIGLIWMM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
YPPLAKVRYEEVNKIFRGGSKIFLFSILQNWIIGPVLMFILAYIFLRNYPEYFMGLVLIG
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LARCIAMVILWNALAKGDAEYAAALVALNSLFQVFFYSTYAYFFIKVVPGWLGYDTKGVV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCEE
LDISMAEIAKSVFIYLGIPFLAGVITRFSLLKSKGREWYETKFIPKLSPTALYALLFTIV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHH
VMFSLKGQYIVKLPLDVVRVAIPLIAYFVLMFFISFYISAKAGFGYARTATLSFTAASNN
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCC
FELAIAVAVATFGLNSGQAFAAVIGPLIEVPVMLWLVNMALKLKDKYFGEGEQYYEWF
CEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]