Click here to switch to the map view.

The map label for this gene is tlpB [H]

Identifier: 78044786

GI number: 78044786

Start: 908455

End: 910398

Strand: Direct

Name: tlpB [H]

Synonym: CHY_1029

Alternate gene names: 78044786

Gene position: 908455-910398 (Clockwise)

Preceding gene: 78043366

Following gene: 78044189

Centisome position: 37.83

GC content: 42.03

Gene sequence:

>1944_bases
ATGTCTAAGACTTTACCACCTTTACCCGAAGGTAGTTTTCAAAAAGAGAAAGGAGTAAAGGCTTCTACCAGTGAGGCGCT
TGTGTCTCAGGCGGAGGTACAGAAAAAGTTAGAAGCTCAGAGAAAACAAGCCAGAACTTTTGCTAAACAGCAGCAAATGG
CTGAACGTTTGGCAGTGGCAACGGAAGAACTATCTTCCAGTGTAGCGGAAGCAACAGCAGCTGTGGAAGAATTAAGAGGT
TCAATGGAGCAAATTTCGGCAGGAGCTGAAGAAGCGAGAGCAGCAACAGCAGAATCGCTCCAAGCTGTAAATCAGATAGT
CAAAAATATAACGATTGCCGCGGAAAATGCTAAAAAGGGAAATGAGAAAGGTGTTGCAGCGGAAAAACTTATACATACTA
CAGGAGAGAGCATAGAGGGTTTAGTAAATGGTGTAGTTGATGCTGCTCAAAGAAATGAAATGGCAGCGGATGCAGTAGCT
AAATTAGAAGCTGAAGCAGAAAACATCGGCAATATTGTAAAAACTGTGGTGAAGATTGCCGACCAGACCAATCTTTTAGC
CTTAAACGCAGCTATCGAAGCGGCCCGTGCGGGGGAACATGGACGCGGTTTTGCGGTAGTAGCCGATGAAGTAAGGACTT
TAGCAGAAATTTCGGAAAAAGCAGCTAATGATATTCGGAACATGGTTAATGAAATTCAAAGTGAGGTTAAGGCTGTTGCT
GATGCAATTAATAACGCTGCAAAAACTGCAAAAGATGAAGCATTAAAGGGAAAAGAAGTTAGTGCTAAGTTAGAAGAAAT
AAACAGGAATATCAAAGAATTAGTAGCGTCTGCAGAAAATGTGGATAAGATGTCACAGGAAATGGAAAGAATGGCTTTGG
AATTCCAAAAGGGAGTTGAAGAAATTGCTACGGCAGCGGAACTACAATCGGGTTCTGCTTATGAAGCTTTAACCGCTATA
GAAGAGCAGGTTAAAGCAATGACTGAAATTTCCGCAGCTTCCAATCAACTGGCCAACATGGCCGATGAGCTGAAACACTC
CACTGACGTGAAAAAATCATCGGAAGAGCTGGCTGCAGCAGCTGAGCAGCTTTCGGCGTCCATTGAAGAAGCTAATCAAA
CTTCCCAGCAAATTATGGCAGCTATAGAACAAATCGATGAAGCCGCTAAAAAACAATCGGCAGCTACTGAACAATCCAAC
GGTGCTGTCATAAGACTTGAACAGTATACTCAACAAGTAGCAGGTTTTGCTCACCGGATGTTAGAGGAAACCAAAACCAT
GGTCGAATTATTAGATGCTAATAAGCAACGAGTACTAAATTTAATTGAAGGAATTAAAAAAGCTGTAGAAGCTAATAGGG
AAAATGTAAAGATGCTAGCAAGTTTATCTCAAAAGTCGCGCCAAATTGACAAAATTGTTGATACTATTGTTAATGTCGGT
ATTCAAACCAATATGCTGGCTGTAAGTGGAGCAATTGAAGCAGCCCGTGCGGGAGAGTACGGTAAAGGGTTTGCAGTAGT
TGCTGCAGATATTCGGAATTTAGCTCAAGACAGCCAGAAAAATGCCGAACAAATAAAAGAACTAGTGCGTAATATTCAGG
AACAGGTGGCGGAAGTTGCTAATGAAATTAATAGATTAGGCGAGTTTATTGAAAAAGAAGCACAATCATCACAAAAAACT
GTTGATTACTTAAATCAACTGACCGATGATATGAACGAACTTTTAGCTGGGAACGAAGTAATTTTAACTGGAAGTGAAGA
AATTGCCACGGCCTTAGGACAATCCAAGAAAGCTATTGAACAAATTGCTACTGCAGCTCAAGAAGCTGCTTCTGCCACAG
CACAAGCCTCCTCGGCAGCTCAAGAGCAGGCTGCGGGCTTTAGAGAGCTGGTTAAGGCTATTGAGGAAATTTCAGCGTTG
GCAGATGAAATGCAGCAACTATAG

Upstream 100 bases:

>100_bases
TTTTAAACTTAAAAAATTTAAAAACGCCATTATTTACCAAAAACCAGGGGCTTAATGTATTTTAGATATTTAATAAAAAT
ATAAAAGAGGAGGTATTGAA

Downstream 100 bases:

>100_bases
AATTTTTCAGCGAGGTGAAGTGGTATGGATGATGCCCGTGGCCAGTTAATTACCTTTCATCTGGGTAAAGAAAGGTATGG
CATAAATTTAAACTATGTTC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 646

Protein sequence:

>647_residues
MSKTLPPLPEGSFQKEKGVKASTSEALVSQAEVQKKLEAQRKQARTFAKQQQMAERLAVATEELSSSVAEATAAVEELRG
SMEQISAGAEEARAATAESLQAVNQIVKNITIAAENAKKGNEKGVAAEKLIHTTGESIEGLVNGVVDAAQRNEMAADAVA
KLEAEAENIGNIVKTVVKIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRTLAEISEKAANDIRNMVNEIQSEVKAVA
DAINNAAKTAKDEALKGKEVSAKLEEINRNIKELVASAENVDKMSQEMERMALEFQKGVEEIATAAELQSGSAYEALTAI
EEQVKAMTEISAASNQLANMADELKHSTDVKKSSEELAAAAEQLSASIEEANQTSQQIMAAIEQIDEAAKKQSAATEQSN
GAVIRLEQYTQQVAGFAHRMLEETKTMVELLDANKQRVLNLIEGIKKAVEANRENVKMLASLSQKSRQIDKIVDTIVNVG
IQTNMLAVSGAIEAARAGEYGKGFAVVAADIRNLAQDSQKNAEQIKELVRNIQEQVAEVANEINRLGEFIEKEAQSSQKT
VDYLNQLTDDMNELLAGNEVILTGSEEIATALGQSKKAIEQIATAAQEAASATAQASSAAQEQAAGFRELVKAIEEISAL
ADEMQQL

Sequences:

>Translated_647_residues
MSKTLPPLPEGSFQKEKGVKASTSEALVSQAEVQKKLEAQRKQARTFAKQQQMAERLAVATEELSSSVAEATAAVEELRG
SMEQISAGAEEARAATAESLQAVNQIVKNITIAAENAKKGNEKGVAAEKLIHTTGESIEGLVNGVVDAAQRNEMAADAVA
KLEAEAENIGNIVKTVVKIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRTLAEISEKAANDIRNMVNEIQSEVKAVA
DAINNAAKTAKDEALKGKEVSAKLEEINRNIKELVASAENVDKMSQEMERMALEFQKGVEEIATAAELQSGSAYEALTAI
EEQVKAMTEISAASNQLANMADELKHSTDVKKSSEELAAAAEQLSASIEEANQTSQQIMAAIEQIDEAAKKQSAATEQSN
GAVIRLEQYTQQVAGFAHRMLEETKTMVELLDANKQRVLNLIEGIKKAVEANRENVKMLASLSQKSRQIDKIVDTIVNVG
IQTNMLAVSGAIEAARAGEYGKGFAVVAADIRNLAQDSQKNAEQIKELVRNIQEQVAEVANEINRLGEFIEKEAQSSQKT
VDYLNQLTDDMNELLAGNEVILTGSEEIATALGQSKKAIEQIATAAQEAASATAQASSAAQEQAAGFRELVKAIEEISAL
ADEMQQL
>Mature_646_residues
SKTLPPLPEGSFQKEKGVKASTSEALVSQAEVQKKLEAQRKQARTFAKQQQMAERLAVATEELSSSVAEATAAVEELRGS
MEQISAGAEEARAATAESLQAVNQIVKNITIAAENAKKGNEKGVAAEKLIHTTGESIEGLVNGVVDAAQRNEMAADAVAK
LEAEAENIGNIVKTVVKIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRTLAEISEKAANDIRNMVNEIQSEVKAVAD
AINNAAKTAKDEALKGKEVSAKLEEINRNIKELVASAENVDKMSQEMERMALEFQKGVEEIATAAELQSGSAYEALTAIE
EQVKAMTEISAASNQLANMADELKHSTDVKKSSEELAAAAEQLSASIEEANQTSQQIMAAIEQIDEAAKKQSAATEQSNG
AVIRLEQYTQQVAGFAHRMLEETKTMVELLDANKQRVLNLIEGIKKAVEANRENVKMLASLSQKSRQIDKIVDTIVNVGI
QTNMLAVSGAIEAARAGEYGKGFAVVAADIRNLAQDSQKNAEQIKELVRNIQEQVAEVANEINRLGEFIEKEAQSSQKTV
DYLNQLTDDMNELLAGNEVILTGSEEIATALGQSKKAIEQIATAAQEAASATAQASSAAQEQAAGFRELVKAIEEISALA
DEMQQL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=288, Percent_Identity=31.5972222222222, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1789453, Length=251, Percent_Identity=29.8804780876494, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787690, Length=232, Percent_Identity=30.1724137931034, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI2367378, Length=196, Percent_Identity=31.1224489795918, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788195, Length=239, Percent_Identity=28.4518828451883, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 69163; Mature: 69032

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTLPPLPEGSFQKEKGVKASTSEALVSQAEVQKKLEAQRKQARTFAKQQQMAERLAVA
CCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEELSSSVAEATAAVEELRGSMEQISAGAEEARAATAESLQAVNQIVKNITIAAENAKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NEKGVAAEKLIHTTGESIEGLVNGVVDAAQRNEMAADAVAKLEAEAENIGNIVKTVVKIA
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQTNLLALNAAIEAARAGEHGRGFAVVADEVRTLAEISEKAANDIRNMVNEIQSEVKAVA
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAINNAAKTAKDEALKGKEVSAKLEEINRNIKELVASAENVDKMSQEMERMALEFQKGVE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIATAAELQSGSAYEALTAIEEQVKAMTEISAASNQLANMADELKHSTDVKKSSEELAAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEQLSASIEEANQTSQQIMAAIEQIDEAAKKQSAATEQSNGAVIRLEQYTQQVAGFAHRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
LEETKTMVELLDANKQRVLNLIEGIKKAVEANRENVKMLASLSQKSRQIDKIVDTIVNVG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IQTNMLAVSGAIEAARAGEYGKGFAVVAADIRNLAQDSQKNAEQIKELVRNIQEQVAEVA
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEINRLGEFIEKEAQSSQKTVDYLNQLTDDMNELLAGNEVILTGSEEIATALGQSKKAIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHH
QIATAAQEAASATAQASSAAQEQAAGFRELVKAIEEISALADEMQQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKTLPPLPEGSFQKEKGVKASTSEALVSQAEVQKKLEAQRKQARTFAKQQQMAERLAVA
CCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEELSSSVAEATAAVEELRGSMEQISAGAEEARAATAESLQAVNQIVKNITIAAENAKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NEKGVAAEKLIHTTGESIEGLVNGVVDAAQRNEMAADAVAKLEAEAENIGNIVKTVVKIA
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQTNLLALNAAIEAARAGEHGRGFAVVADEVRTLAEISEKAANDIRNMVNEIQSEVKAVA
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAINNAAKTAKDEALKGKEVSAKLEEINRNIKELVASAENVDKMSQEMERMALEFQKGVE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIATAAELQSGSAYEALTAIEEQVKAMTEISAASNQLANMADELKHSTDVKKSSEELAAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEQLSASIEEANQTSQQIMAAIEQIDEAAKKQSAATEQSNGAVIRLEQYTQQVAGFAHRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
LEETKTMVELLDANKQRVLNLIEGIKKAVEANRENVKMLASLSQKSRQIDKIVDTIVNVG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IQTNMLAVSGAIEAARAGEYGKGFAVVAADIRNLAQDSQKNAEQIKELVRNIQEQVAEVA
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEINRLGEFIEKEAQSSQKTVDYLNQLTDDMNELLAGNEVILTGSEEIATALGQSKKAIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHH
QIATAAQEAASATAQASSAAQEQAAGFRELVKAIEEISALADEMQQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]