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The map label for this gene is dapL [H]

Identifier: 78044747

GI number: 78044747

Start: 1045612

End: 1046763

Strand: Direct

Name: dapL [H]

Synonym: CHY_1173

Alternate gene names: 78044747

Gene position: 1045612-1046763 (Clockwise)

Preceding gene: 78043313

Following gene: 78043820

Centisome position: 43.54

GC content: 37.07

Gene sequence:

>1152_bases
ATGAAATTTTCAACCGGTATTTTTGACGAATTATCGATGCTGATTAAAAAAGTATCTAAAGAGCGCGACGTGATAAATTT
AAGCATCGGAAGTCCCGATTTACCGCCACACCCTAAAATAATTGAAGTGTTGGCCAAAGAGGTACAGGATTTCCAAAACT
ATGGATATACCTTAAATCCAGGCTTAGAGGAATTAAGAGAAGGTTTAATTGCCTGGTATCAAAAAAAGTATGGAGTTAAT
TTAAAAATTGATGAAACCCTTGTATTACTCGGCTCGCAAGAGGGCTTGGCTCATTTACCCCTTTCTTTCTTGAATCCGGG
AGATCTGGTGTTAGTACCAAATCCCGGTTATCCTATATATGAAGCGGCAGCAAAACTTGCGGGAGCAAAGATTTATTATT
ACCCTTTATTAGAGGAAAATAATTATCGTTTGGACATTGAAAAGATTCCTTATGATATTTTACGGACGGCAAAAATTATT
TTTCTTAACTACCCTAATAACCCTTTGACTGCCATGGCCAATTACGAATTTTTTGAAAAACTTGTATTTTATGCCAAAAA
ATATGGTTTTATCTTAGTTAATGATTTGGCTTATGGAGAATTAACTTTTGATGAGACCAGAAGTATTAGTCTTTTAGAAA
TTCCTGAAGCAATTGACGTTGCAGTTGAATTTTATTCCGTTTCAAAATCATTTAATTTAGCGGGAATCAGGGTAGGTTTT
GCTGCCGGTAATCAAAAGGTTATTTCCGCTTTAACAATATTAAAATCAAATATTGATTACGGCGTTTTTAAGCCTTTGCA
AAAAGCGGCTTTAGAAGCGTTTAAGCTTAGAGAGGTTATTATCCCGGATTTAGTTAAGACTTATGAAAAAAGGAGAAATG
TTCTTATTAAAACTTTATCCGAGTATGGCTGGCAAGTAAAACCTCCTTTAGCTACAATGTTTGTCTGGGCCCAGCTTCCT
GATGGAATAAAAGATTCAAGAAAGTTTTCTTTAGATCTTCTCACCAATGCTGGTGTAGCAGTAACTCCGGGTATCGGATT
TGGAGACCTCGGTGAGGGGTACGTTCGAATTGCCCTGGTGGCGGACGAGGATAAACTTGCGGAAGCAGGAAAAAGAATCG
GTGAATATTTGCAGTACAGGAGGGTAGTATGA

Upstream 100 bases:

>100_bases
ATTTTTACCCGGTGAGGTTGAAAAAATATTTTACCAAAATATTGATAGAGTTTTAAAAGAAGTGTTATATTAATTTTAAA
AATTAAAAGGTGGGTAGGGG

Downstream 100 bases:

>100_bases
GAATTGCGGTTATTGATGGTCAGGGCGGAGGCATTGGGAAGTACATTATTGAAAGAATACGTAAAGCTTTTGGCCAGGAG
ATTGAAATAATCGCTATTGG

Product: aminotransferase, classes I and II

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKFSTGIFDELSMLIKKVSKERDVINLSIGSPDLPPHPKIIEVLAKEVQDFQNYGYTLNPGLEELREGLIAWYQKKYGVN
LKIDETLVLLGSQEGLAHLPLSFLNPGDLVLVPNPGYPIYEAAAKLAGAKIYYYPLLEENNYRLDIEKIPYDILRTAKII
FLNYPNNPLTAMANYEFFEKLVFYAKKYGFILVNDLAYGELTFDETRSISLLEIPEAIDVAVEFYSVSKSFNLAGIRVGF
AAGNQKVISALTILKSNIDYGVFKPLQKAALEAFKLREVIIPDLVKTYEKRRNVLIKTLSEYGWQVKPPLATMFVWAQLP
DGIKDSRKFSLDLLTNAGVAVTPGIGFGDLGEGYVRIALVADEDKLAEAGKRIGEYLQYRRVV

Sequences:

>Translated_383_residues
MKFSTGIFDELSMLIKKVSKERDVINLSIGSPDLPPHPKIIEVLAKEVQDFQNYGYTLNPGLEELREGLIAWYQKKYGVN
LKIDETLVLLGSQEGLAHLPLSFLNPGDLVLVPNPGYPIYEAAAKLAGAKIYYYPLLEENNYRLDIEKIPYDILRTAKII
FLNYPNNPLTAMANYEFFEKLVFYAKKYGFILVNDLAYGELTFDETRSISLLEIPEAIDVAVEFYSVSKSFNLAGIRVGF
AAGNQKVISALTILKSNIDYGVFKPLQKAALEAFKLREVIIPDLVKTYEKRRNVLIKTLSEYGWQVKPPLATMFVWAQLP
DGIKDSRKFSLDLLTNAGVAVTPGIGFGDLGEGYVRIALVADEDKLAEAGKRIGEYLQYRRVV
>Mature_383_residues
MKFSTGIFDELSMLIKKVSKERDVINLSIGSPDLPPHPKIIEVLAKEVQDFQNYGYTLNPGLEELREGLIAWYQKKYGVN
LKIDETLVLLGSQEGLAHLPLSFLNPGDLVLVPNPGYPIYEAAAKLAGAKIYYYPLLEENNYRLDIEKIPYDILRTAKII
FLNYPNNPLTAMANYEFFEKLVFYAKKYGFILVNDLAYGELTFDETRSISLLEIPEAIDVAVEFYSVSKSFNLAGIRVGF
AAGNQKVISALTILKSNIDYGVFKPLQKAALEAFKLREVIIPDLVKTYEKRRNVLIKTLSEYGWQVKPPLATMFVWAQLP
DGIKDSRKFSLDLLTNAGVAVTPGIGFGDLGEGYVRIALVADEDKLAEAGKRIGEYLQYRRVV

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=21.7171717171717, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=21.7171717171717, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI56713256, Length=304, Percent_Identity=25.3289473684211, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI56713254, Length=304, Percent_Identity=25.3289473684211, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4507369, Length=228, Percent_Identity=22.3684210526316, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI169881281, Length=386, Percent_Identity=20.7253886010363, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=366, Percent_Identity=41.2568306010929, Blast_Score=301, Evalue=3e-83,
Organism=Escherichia coli, GI1786816, Length=381, Percent_Identity=23.8845144356955, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=25.3886010362694, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788332, Length=254, Percent_Identity=30.3149606299213, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=379, Percent_Identity=25.5936675461741, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=379, Percent_Identity=25.5936675461741, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=323, Percent_Identity=24.7678018575851, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=375, Percent_Identity=24.2666666666667, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=385, Percent_Identity=24.4155844155844, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=353, Percent_Identity=25.4957507082153, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=24.7422680412371, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=24.7422680412371, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=24.7422680412371, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=24.7422680412371, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI18859735, Length=387, Percent_Identity=21.4470284237726, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43055; Mature: 43055

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSTGIFDELSMLIKKVSKERDVINLSIGSPDLPPHPKIIEVLAKEVQDFQNYGYTLNP
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEECC
GLEELREGLIAWYQKKYGVNLKIDETLVLLGSQEGLAHLPLSFLNPGDLVLVPNPGYPIY
CHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCCCCCCHHHCCCCCEEEECCCCCCHH
EAAAKLAGAKIYYYPLLEENNYRLDIEKIPYDILRTAKIIFLNYPNNPLTAMANYEFFEK
HHHHHHCCCEEEEEEEEECCCCEEEHHHCCHHHHCCEEEEEEECCCCCEEEEECHHHHHH
LVFYAKKYGFILVNDLAYGELTFDETRSISLLEIPEAIDVAVEFYSVSKSFNLAGIRVGF
HHHHHHHCCEEEEECCCCCEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEEEE
AAGNQKVISALTILKSNIDYGVFKPLQKAALEAFKLREVIIPDLVKTYEKRRNVLIKTLS
ECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYGWQVKPPLATMFVWAQLPDGIKDSRKFSLDLLTNAGVAVTPGIGFGDLGEGYVRIALV
HCCCEECCCHHHHHEEHHCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCEEEEEEE
ADEDKLAEAGKRIGEYLQYRRVV
ECCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFSTGIFDELSMLIKKVSKERDVINLSIGSPDLPPHPKIIEVLAKEVQDFQNYGYTLNP
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEECC
GLEELREGLIAWYQKKYGVNLKIDETLVLLGSQEGLAHLPLSFLNPGDLVLVPNPGYPIY
CHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCCCCCCHHHCCCCCEEEECCCCCCHH
EAAAKLAGAKIYYYPLLEENNYRLDIEKIPYDILRTAKIIFLNYPNNPLTAMANYEFFEK
HHHHHHCCCEEEEEEEEECCCCEEEHHHCCHHHHCCEEEEEEECCCCCEEEEECHHHHHH
LVFYAKKYGFILVNDLAYGELTFDETRSISLLEIPEAIDVAVEFYSVSKSFNLAGIRVGF
HHHHHHHCCEEEEECCCCCEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEEEE
AAGNQKVISALTILKSNIDYGVFKPLQKAALEAFKLREVIIPDLVKTYEKRRNVLIKTLS
ECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYGWQVKPPLATMFVWAQLPDGIKDSRKFSLDLLTNAGVAVTPGIGFGDLGEGYVRIALV
HCCCEECCCHHHHHEEHHCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCEEEEEEE
ADEDKLAEAGKRIGEYLQYRRVV
ECCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA