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The map label for this gene is accD

Identifier: 78044562

GI number: 78044562

Start: 1015209

End: 1016051

Strand: Direct

Name: accD

Synonym: CHY_1141

Alternate gene names: 78044562

Gene position: 1015209-1016051 (Clockwise)

Preceding gene: 78045130

Following gene: 78044709

Centisome position: 42.27

GC content: 41.16

Gene sequence:

>843_bases
ATGTTTGACTTTTTTCGCAAATCGAAGTATGTAACTGTAAAGCCGGAAACTAAACAAAAAGAGATTCCCGATGGTTTGTG
GCAGAAATGTCCCCGGTGTGGGGAAATTATTTTTAACAAGGAATTGGAGAAAAATTTTAAAGTTTGTCCAAAATGCGGGT
ATCATTTTAAAATTAGTGCCTGGGAAAGAATTAAACTCTTATGCGATGAAAATAGTTTTGTAGAATTTGGCCGGGAAATT
AGTGGGGGCAATCCTTTAAATTTTCCAGGATATGAAGAGAAGTTAGCGGAAGCCCGGGAAAAAACCGGCTTAAAAGAAGC
GGTAGTTACCGGATTGGGAAAAATTAATGGTAGAGAAGTAGTTTTGGCAATAATGGACCCGAATTTTATTATGGCCAGTA
TGGGCACGGCTGTAGGGGAAAAAATATGTTTAGCGATGGAAAAAGCTCTGGAGAAAAAGCTACCGCTTGTAGTCTTTACT
GCATCCGGAGGAGCTCGGATGCAGGAGGGAATTTTTTCTTTAATGCAGATGGCCAAAACGGTTCAACTGGTAAATCGTTT
AAATGCAGAAAAAATTTTTTATTTGGTAGTTATGACCGATCCTACTACCGGCGGTGTTTCGGCAAGTTTTGCAGCCTTGG
GTGATATAATATTGGCTGAACCGGGGGCTTTAATAGGATTTGCCGGACCCCGGGTTATTGAGCAAACTATCCGGCAAAAG
CTTCCCGAAGGTTTTCAACGAGCAGAATTTCTGGAGCAGCACGGTTTTATCGATGCTGTGGTTTCCAGAGAGCAGCAAAA
AGAAGTTATTACAAAACTCTTGGCTTGGCACAGCCAAAAGTAA

Upstream 100 bases:

>100_bases
AGGGATCGAAGGAGACAATTCCACCTATGAAGTTATGGTACCCGAAGCAGAAGTGGAAGAAGCGATGGAAATTTTAAATG
AAATGTAAAGGAGTTTTGCT

Downstream 100 bases:

>100_bases
ATTGGGGGCAGCGTATGGCAAATTTTTTATTTGAGTTTGAAAAACCTTTGGTTGAATTAGAAAATAAAATATCTGACTTA
AAAAAGTTTGCTGAAGAGAA

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MFDFFRKSKYVTVKPETKQKEIPDGLWQKCPRCGEIIFNKELEKNFKVCPKCGYHFKISAWERIKLLCDENSFVEFGREI
SGGNPLNFPGYEEKLAEAREKTGLKEAVVTGLGKINGREVVLAIMDPNFIMASMGTAVGEKICLAMEKALEKKLPLVVFT
ASGGARMQEGIFSLMQMAKTVQLVNRLNAEKIFYLVVMTDPTTGGVSASFAALGDIILAEPGALIGFAGPRVIEQTIRQK
LPEGFQRAEFLEQHGFIDAVVSREQQKEVITKLLAWHSQK

Sequences:

>Translated_280_residues
MFDFFRKSKYVTVKPETKQKEIPDGLWQKCPRCGEIIFNKELEKNFKVCPKCGYHFKISAWERIKLLCDENSFVEFGREI
SGGNPLNFPGYEEKLAEAREKTGLKEAVVTGLGKINGREVVLAIMDPNFIMASMGTAVGEKICLAMEKALEKKLPLVVFT
ASGGARMQEGIFSLMQMAKTVQLVNRLNAEKIFYLVVMTDPTTGGVSASFAALGDIILAEPGALIGFAGPRVIEQTIRQK
LPEGFQRAEFLEQHGFIDAVVSREQQKEVITKLLAWHSQK
>Mature_280_residues
MFDFFRKSKYVTVKPETKQKEIPDGLWQKCPRCGEIIFNKELEKNFKVCPKCGYHFKISAWERIKLLCDENSFVEFGREI
SGGNPLNFPGYEEKLAEAREKTGLKEAVVTGLGKINGREVVLAIMDPNFIMASMGTAVGEKICLAMEKALEKKLPLVVFT
ASGGARMQEGIFSLMQMAKTVQLVNRLNAEKIFYLVVMTDPTTGGVSASFAALGDIILAEPGALIGFAGPRVIEQTIRQK
LPEGFQRAEFLEQHGFIDAVVSREQQKEVITKLLAWHSQK

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Homo sapiens, GI119943100, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788655, Length=262, Percent_Identity=48.8549618320611, Blast_Score=262, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_CARHZ (Q3ACZ8)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359986.1
- ProteinModelPortal:   Q3ACZ8
- SMR:   Q3ACZ8
- STRING:   Q3ACZ8
- GeneID:   3727681
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_1141
- NMPDR:   fig|246194.3.peg.1187
- TIGR:   CHY_1141
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- BioCyc:   CHYD246194:CHY_1141-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 31271; Mature: 31271

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDFFRKSKYVTVKPETKQKEIPDGLWQKCPRCGEIIFNKELEKNFKVCPKCGYHFKISA
CCCCHHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEEECH
WERIKLLCDENSFVEFGREISGGNPLNFPGYEEKLAEAREKTGLKEAVVTGLGKINGREV
HHEEHEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEE
VLAIMDPNFIMASMGTAVGEKICLAMEKALEKKLPLVVFTASGGARMQEGIFSLMQMAKT
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
VQLVNRLNAEKIFYLVVMTDPTTGGVSASFAALGDIILAEPGALIGFAGPRVIEQTIRQK
HHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHEECCCCEEECCCHHHHHHHHHHH
LPEGFQRAEFLEQHGFIDAVVSREQQKEVITKLLAWHSQK
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFDFFRKSKYVTVKPETKQKEIPDGLWQKCPRCGEIIFNKELEKNFKVCPKCGYHFKISA
CCCCHHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEEECH
WERIKLLCDENSFVEFGREISGGNPLNFPGYEEKLAEAREKTGLKEAVVTGLGKINGREV
HHEEHEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEE
VLAIMDPNFIMASMGTAVGEKICLAMEKALEKKLPLVVFTASGGARMQEGIFSLMQMAKT
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
VQLVNRLNAEKIFYLVVMTDPTTGGVSASFAALGDIILAEPGALIGFAGPRVIEQTIRQK
HHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHEECCCCEEECCCHHHHHHHHHHH
LPEGFQRAEFLEQHGFIDAVVSREQQKEVITKLLAWHSQK
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA