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The map label for this gene is fusA1 [H]

Identifier: 78044525

GI number: 78044525

Start: 849185

End: 851203

Strand: Direct

Name: fusA1 [H]

Synonym: CHY_0961

Alternate gene names: 78044525

Gene position: 849185-851203 (Clockwise)

Preceding gene: 78044029

Following gene: 78045015

Centisome position: 35.36

GC content: 44.97

Gene sequence:

>2019_bases
ATGAAAAGCTACCCTACAGAGTTTTTAAGAAACATCGGTATCTTTGCCCACAGCGGGGCGGGCAAAACCAGTCTTACCGA
AGCTTTACTTTACAATACTGGAGTATTGAAAAGAATGGGCCGGGTGGAGGACGGAAATACTGTTTCTGATTACCACCCCG
AGGAAATTAAAAGGAAGGTGACCATTCACGCTTCCCTTGTGCCCTGCGAGTGGAACAACCATAAGTTAAACTTTATCGAT
ACTCCGGGATATGCGGATTTTATCGGTGAGGTAAAAAGTGTTTTAAAAGTTGTAGAAGGGGCAATATTTGTGGTTTGCGC
GGCGTCCGGCGTGGAGATTCAGACGGAAGTGGTCTGGAATCTTGCAGACAATGCTGGTTTGCCGCGTTTTGTGTTTATTA
ACAAAATAGAACGGGAAAATGCCAATTTTGAAAAAACGTTAAATCAGATCCGGGAGATTCTTTCGGCTAAAGTAGTACCC
CTTCATTTACCGATTGGCGAAGGGGAAAACTTTAAAGGATATATTGATGTTTTAAAAAATAAAGCTTACTTCTTTGATGG
TACCAATTTAACGGAAGGGGCTATCCCCGCCGAGTATGAAGAACGAGTTTTAGAAGCCTGGCTGCAATTAACGGAAGCTG
CGGCGGAAAATGATGATGAGCTATTAATGATGTATTTGGATGGAGCGGAACTGACCCCTGAGCAGGTTGCACTGGGGCTC
AAAAAAGGGGTACGGGCCGGCAAACTTTACCCGCTTTTTGTGGGCTCTGCCACAAAAAATATCGGCATTAGAGATTTATT
GGATGCTTCCTGTGAACTGCTGCCGCCTCCCCAAAAAAATTATGATCACCCGGTGGCTTATGTGTTTAAAACCTTAGCTG
ACCCGTATGTAGGCAGGATTAACTTTGTTAAAGTTTTGGGGGGTTCTTTAAAGCCAGAAACTACACTCTATAACTTTAAA
AAAGATAAACCGGAAAAAATCGGCCATATCCTTTTTATGCGAGGCAAAGATCAAGTTCAAAGCCAGGAGGTAAATGCCGG
AGATATCGCTTGCTTAATAAAGCTTTCCGAAACCGGTACCGGCGATGTTTTGAGTTTAAAAGATAAACCGGTGGAAATTG
AACCGGTAGATTATCCCACTCCTAACATGACCATTGCCATTCTCCCCAAAAGTAAAAACGATGAAGACCGCCTTTCCACT
GCTCTCCATCGCGCCTTAGAGGAAGACCCCACACTTAGCCTTGAGAAAAACCTGGAAACCCGCCAGAACCTCCTTTCCGG
CATGGGGGAACTCCATTTGGAAATTGTTCTCGAAGCAATTAAACGGAAGTATGGTGTTGAAGTGGTAACCGAAGAATTAC
GGGTGCCTTACCGGGAGACTATCCGGAAAACGGTTCAGGTGGAAGGTAAATATAAAAAGCAAACCGGTGGCCGGGGTCAG
TACGGCCATGTGTGGCTTAGATTAGAACCCCTGCCGGATAAAGAGTTTGAGTTTGGTGAAGAGATTTTTGGCGGTGCCGT
TCCCAAACAGTATTTTCCGGCGGTAGAAAAAGGAATTCGCGAAGCGTTAAATGAAGGAGTACTGGCCGGTTATAAAGTAA
TGAATGTGCGGGCGGTACTGTACGATGGTTCGTATCACCCGGTGGACTCTTCCGAACTGGCTTTTAAGATTGCGGCCAGT
CAGGCTTTCAAGAAAGGGGTTAAGGAAGCAAATCCGGTACTTTTGGAACCGGTAATGCTTGTTGAAGTGACGGTGCCGGA
GCAATTTATGGGGGATGTGATCAGCGACTTTAACGGTAAACGTGGCCATGTTCTTGGCATGGAAACCCAGGGACGCTGGG
CCAGGGTTAAAGCTTATGTACCGTATGCCGAGATGTTAAAATATAATATTGACTTAAAAGCGATGACCCAGGCCAGGGGC
TTCTACACCATGACTTTCAGCCACTACCAGGAAGTACCTCCCAAACTACAGGAAGAAATTATAAAGAAAGCAAACTTAAA
TAAGAAAGAAGAAGAATAA

Upstream 100 bases:

>100_bases
TTCCCGTAGAATTAAAAAAATTTCAAAAAAATAAAAGGAAAACCCGAAATTATGCTGAAATAATATATTACTAATAAAAA
ATCCTTAGGAGGGCTTTTAA

Downstream 100 bases:

>100_bases
ACCAGTTTAGCAAATTTTTCTTGACGATTTTTCCTGATTAATGATTTAATTTTGTATGGCAAGATTGGTGTAAAGTACAA
TTAAATAACATTTTCCGAAA

Product: translation elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MKSYPTEFLRNIGIFAHSGAGKTSLTEALLYNTGVLKRMGRVEDGNTVSDYHPEEIKRKVTIHASLVPCEWNNHKLNFID
TPGYADFIGEVKSVLKVVEGAIFVVCAASGVEIQTEVVWNLADNAGLPRFVFINKIERENANFEKTLNQIREILSAKVVP
LHLPIGEGENFKGYIDVLKNKAYFFDGTNLTEGAIPAEYEERVLEAWLQLTEAAAENDDELLMMYLDGAELTPEQVALGL
KKGVRAGKLYPLFVGSATKNIGIRDLLDASCELLPPPQKNYDHPVAYVFKTLADPYVGRINFVKVLGGSLKPETTLYNFK
KDKPEKIGHILFMRGKDQVQSQEVNAGDIACLIKLSETGTGDVLSLKDKPVEIEPVDYPTPNMTIAILPKSKNDEDRLST
ALHRALEEDPTLSLEKNLETRQNLLSGMGELHLEIVLEAIKRKYGVEVVTEELRVPYRETIRKTVQVEGKYKKQTGGRGQ
YGHVWLRLEPLPDKEFEFGEEIFGGAVPKQYFPAVEKGIREALNEGVLAGYKVMNVRAVLYDGSYHPVDSSELAFKIAAS
QAFKKGVKEANPVLLEPVMLVEVTVPEQFMGDVISDFNGKRGHVLGMETQGRWARVKAYVPYAEMLKYNIDLKAMTQARG
FYTMTFSHYQEVPPKLQEEIIKKANLNKKEEE

Sequences:

>Translated_672_residues
MKSYPTEFLRNIGIFAHSGAGKTSLTEALLYNTGVLKRMGRVEDGNTVSDYHPEEIKRKVTIHASLVPCEWNNHKLNFID
TPGYADFIGEVKSVLKVVEGAIFVVCAASGVEIQTEVVWNLADNAGLPRFVFINKIERENANFEKTLNQIREILSAKVVP
LHLPIGEGENFKGYIDVLKNKAYFFDGTNLTEGAIPAEYEERVLEAWLQLTEAAAENDDELLMMYLDGAELTPEQVALGL
KKGVRAGKLYPLFVGSATKNIGIRDLLDASCELLPPPQKNYDHPVAYVFKTLADPYVGRINFVKVLGGSLKPETTLYNFK
KDKPEKIGHILFMRGKDQVQSQEVNAGDIACLIKLSETGTGDVLSLKDKPVEIEPVDYPTPNMTIAILPKSKNDEDRLST
ALHRALEEDPTLSLEKNLETRQNLLSGMGELHLEIVLEAIKRKYGVEVVTEELRVPYRETIRKTVQVEGKYKKQTGGRGQ
YGHVWLRLEPLPDKEFEFGEEIFGGAVPKQYFPAVEKGIREALNEGVLAGYKVMNVRAVLYDGSYHPVDSSELAFKIAAS
QAFKKGVKEANPVLLEPVMLVEVTVPEQFMGDVISDFNGKRGHVLGMETQGRWARVKAYVPYAEMLKYNIDLKAMTQARG
FYTMTFSHYQEVPPKLQEEIIKKANLNKKEEE
>Mature_672_residues
MKSYPTEFLRNIGIFAHSGAGKTSLTEALLYNTGVLKRMGRVEDGNTVSDYHPEEIKRKVTIHASLVPCEWNNHKLNFID
TPGYADFIGEVKSVLKVVEGAIFVVCAASGVEIQTEVVWNLADNAGLPRFVFINKIERENANFEKTLNQIREILSAKVVP
LHLPIGEGENFKGYIDVLKNKAYFFDGTNLTEGAIPAEYEERVLEAWLQLTEAAAENDDELLMMYLDGAELTPEQVALGL
KKGVRAGKLYPLFVGSATKNIGIRDLLDASCELLPPPQKNYDHPVAYVFKTLADPYVGRINFVKVLGGSLKPETTLYNFK
KDKPEKIGHILFMRGKDQVQSQEVNAGDIACLIKLSETGTGDVLSLKDKPVEIEPVDYPTPNMTIAILPKSKNDEDRLST
ALHRALEEDPTLSLEKNLETRQNLLSGMGELHLEIVLEAIKRKYGVEVVTEELRVPYRETIRKTVQVEGKYKKQTGGRGQ
YGHVWLRLEPLPDKEFEFGEEIFGGAVPKQYFPAVEKGIREALNEGVLAGYKVMNVRAVLYDGSYHPVDSSELAFKIAAS
QAFKKGVKEANPVLLEPVMLVEVTVPEQFMGDVISDFNGKRGHVLGMETQGRWARVKAYVPYAEMLKYNIDLKAMTQARG
FYTMTFSHYQEVPPKLQEEIIKKANLNKKEEE

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=695, Percent_Identity=35.8273381294964, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI19923640, Length=712, Percent_Identity=32.4438202247191, Blast_Score=343, Evalue=3e-94,
Organism=Homo sapiens, GI25306287, Length=705, Percent_Identity=31.2056737588652, Blast_Score=305, Evalue=9e-83,
Organism=Homo sapiens, GI25306283, Length=383, Percent_Identity=36.5535248041775, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI157426893, Length=158, Percent_Identity=35.4430379746835, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI94966754, Length=137, Percent_Identity=31.3868613138686, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI4503483, Length=147, Percent_Identity=31.2925170068027, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789738, Length=698, Percent_Identity=40.6876790830946, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1790835, Length=465, Percent_Identity=24.9462365591398, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI48994988, Length=162, Percent_Identity=37.6543209876543, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788922, Length=151, Percent_Identity=34.4370860927152, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533571, Length=691, Percent_Identity=30.3907380607815, Blast_Score=356, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI17556745, Length=705, Percent_Identity=27.6595744680851, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17506493, Length=389, Percent_Identity=25.9640102827763, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17557151, Length=154, Percent_Identity=29.2207792207792, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323098, Length=687, Percent_Identity=32.8966521106259, Blast_Score=375, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6322359, Length=782, Percent_Identity=26.8542199488491, Blast_Score=240, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6324707, Length=146, Percent_Identity=30.1369863013699, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320593, Length=146, Percent_Identity=30.1369863013699, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323320, Length=156, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582462, Length=692, Percent_Identity=33.9595375722543, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI221458488, Length=712, Percent_Identity=27.3876404494382, Blast_Score=242, Evalue=5e-64,
Organism=Drosophila melanogaster, GI78706572, Length=152, Percent_Identity=33.5526315789474, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585711, Length=150, Percent_Identity=29.3333333333333, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24585713, Length=150, Percent_Identity=29.3333333333333, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24585709, Length=150, Percent_Identity=29.3333333333333, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 75292; Mature: 75292

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSYPTEFLRNIGIFAHSGAGKTSLTEALLYNTGVLKRMGRVEDGNTVSDYHPEEIKRKV
CCCCHHHHHHHCCCEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHCEEE
TIHASLVPCEWNNHKLNFIDTPGYADFIGEVKSVLKVVEGAIFVVCAASGVEIQTEVVWN
EEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEEEE
LADNAGLPRFVFINKIERENANFEKTLNQIREILSAKVVPLHLPIGEGENFKGYIDVLKN
ECCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCC
KAYFFDGTNLTEGAIPAEYEERVLEAWLQLTEAAAENDDELLMMYLDGAELTPEQVALGL
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHH
KKGVRAGKLYPLFVGSATKNIGIRDLLDASCELLPPPQKNYDHPVAYVFKTLADPYVGRI
HHCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCE
NFVKVLGGSLKPETTLYNFKKDKPEKIGHILFMRGKDQVQSQEVNAGDIACLIKLSETGT
EEEEECCCCCCCCCEEECCCCCCHHHCCEEEEECCCHHHHHCCCCCCCEEEEEEEECCCC
GDVLSLKDKPVEIEPVDYPTPNMTIAILPKSKNDEDRLSTALHRALEEDPTLSLEKNLET
CCEEEECCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEHHHCHHH
RQNLLSGMGELHLEIVLEAIKRKYGVEVVTEELRVPYRETIRKTVQVEGKYKKQTGGRGQ
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHEECCCEECCCCCCCC
YGHVWLRLEPLPDKEFEFGEEIFGGAVPKQYFPAVEKGIREALNEGVLAGYKVMNVRAVL
CCEEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEE
YDGSYHPVDSSELAFKIAASQAFKKGVKEANPVLLEPVMLVEVTVPEQFMGDVISDFNGK
ECCCCCCCCCCHHEEEHHHHHHHHHHHHHCCCEEECCEEEEEEECCHHHHHHHHHHCCCC
RGHVLGMETQGRWARVKAYVPYAEMLKYNIDLKAMTQARGFYTMTFSHYQEVPPKLQEEI
CCCEEEECCCCCEEEEEEECCHHHHHHCCCCCEEHHCCCCEEEEEEHHHHHCCHHHHHHH
IKKANLNKKEEE
HHHCCCCCCCCC
>Mature Secondary Structure
MKSYPTEFLRNIGIFAHSGAGKTSLTEALLYNTGVLKRMGRVEDGNTVSDYHPEEIKRKV
CCCCHHHHHHHCCCEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHCEEE
TIHASLVPCEWNNHKLNFIDTPGYADFIGEVKSVLKVVEGAIFVVCAASGVEIQTEVVWN
EEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEEEE
LADNAGLPRFVFINKIERENANFEKTLNQIREILSAKVVPLHLPIGEGENFKGYIDVLKN
ECCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCC
KAYFFDGTNLTEGAIPAEYEERVLEAWLQLTEAAAENDDELLMMYLDGAELTPEQVALGL
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHH
KKGVRAGKLYPLFVGSATKNIGIRDLLDASCELLPPPQKNYDHPVAYVFKTLADPYVGRI
HHCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCE
NFVKVLGGSLKPETTLYNFKKDKPEKIGHILFMRGKDQVQSQEVNAGDIACLIKLSETGT
EEEEECCCCCCCCCEEECCCCCCHHHCCEEEEECCCHHHHHCCCCCCCEEEEEEEECCCC
GDVLSLKDKPVEIEPVDYPTPNMTIAILPKSKNDEDRLSTALHRALEEDPTLSLEKNLET
CCEEEECCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEHHHCHHH
RQNLLSGMGELHLEIVLEAIKRKYGVEVVTEELRVPYRETIRKTVQVEGKYKKQTGGRGQ
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHEECCCEECCCCCCCC
YGHVWLRLEPLPDKEFEFGEEIFGGAVPKQYFPAVEKGIREALNEGVLAGYKVMNVRAVL
CCEEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEE
YDGSYHPVDSSELAFKIAASQAFKKGVKEANPVLLEPVMLVEVTVPEQFMGDVISDFNGK
ECCCCCCCCCCHHEEEHHHHHHHHHHHHHCCCEEECCEEEEEEECCHHHHHHHHHHCCCC
RGHVLGMETQGRWARVKAYVPYAEMLKYNIDLKAMTQARGFYTMTFSHYQEVPPKLQEEI
CCCEEEECCCCCEEEEEEECCHHHHHHCCCCCEEHHCCCCEEEEEEHHHHHCCHHHHHHH
IKKANLNKKEEE
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA