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The map label for this gene is dapB

Identifier: 78044285

GI number: 78044285

Start: 1023741

End: 1024532

Strand: Direct

Name: dapB

Synonym: CHY_1151

Alternate gene names: 78044285

Gene position: 1023741-1024532 (Clockwise)

Preceding gene: 78043788

Following gene: 78043557

Centisome position: 42.63

GC content: 41.04

Gene sequence:

>792_bases
ATGGCGCGAATAGTTATGCTTGGGGCTTGTGGTAAAATGGGAAGAGAAATAAGTAAAAACCTTCTAATGCATTCCGAACA
TGAGTTAGTTGGATTTGTTGACGTGGTAAATGTGGGGCAGGATTTCGGTGAAATTTTGGGTATTTCCCGGTTGGGTAAAA
CGGTGGAGGATAACCTAAAAGAGGTAATTTTAAAAACGAACCCCGAGATTGTTTTGGATTTTTCGCGGGCTTCCGGAGCA
TTTACTAACATTTTAATAGCGTTAGAAAACAAGGTAAGAGTGGTCTCGGGTACTACCGGTTTTTCCCAGGAGCAGATTAA
AAAAATTGAGGATGTGAGTAATGCAAATAACCTGGGTTGTATCATAGCTCCCAATTTTTCTATTGGTGCCTTATTATTGA
TGAAGTTGGCGCAAATGGCAGCAAAATATTTTTCCCATGTAGAAATAATTGAATACCACCATAATTTAAAAGTTGATGCT
CCATCCGGAACTGCCATAAAAACTGCAGAACTCCTTAGCTCTATCCGGGAAAATCAGCCCAGCGCAATTCAAGAAGAAGA
AAAAATTCCCGGGAGCCGTGGCGGAGACTACAGGGGTATAAAAATACATAGTGTTCGTCTTCCCGGGTTAGTTGCCCACC
AGGAGGTAATATTTGGGGGCAGAGGCCAGAGTCTAACGTTGAGGCATGATGTTTACAGCCGGGAAAGCTATTTGGATGGA
ATCTTATTTGCTCTTAAAAAGGTTTTGGAATTGGATAGGTTTGTGTTTGGTCTGGATGAATTATTGTTTTAA

Upstream 100 bases:

>100_bases
ACATATTAAACCGGGAAGACCGGTTTTTTTCTTGACAGAAAGGGCATTTAAATAGAAAATAATTAAAAATGTGTTTTTAT
ACAAATTAAGGAGGATTTTT

Downstream 100 bases:

>100_bases
ACTTTAGGACAAGCACCGCCCAACTCCCATGTTCATATACTGCTATTAGCTTTTAACCACTGGGGGTTGGAGCGATGAAA
CAGGTCTTGCTGGGAATTAA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MARIVMLGACGKMGREISKNLLMHSEHELVGFVDVVNVGQDFGEILGISRLGKTVEDNLKEVILKTNPEIVLDFSRASGA
FTNILIALENKVRVVSGTTGFSQEQIKKIEDVSNANNLGCIIAPNFSIGALLLMKLAQMAAKYFSHVEIIEYHHNLKVDA
PSGTAIKTAELLSSIRENQPSAIQEEEKIPGSRGGDYRGIKIHSVRLPGLVAHQEVIFGGRGQSLTLRHDVYSRESYLDG
ILFALKKVLELDRFVFGLDELLF

Sequences:

>Translated_263_residues
MARIVMLGACGKMGREISKNLLMHSEHELVGFVDVVNVGQDFGEILGISRLGKTVEDNLKEVILKTNPEIVLDFSRASGA
FTNILIALENKVRVVSGTTGFSQEQIKKIEDVSNANNLGCIIAPNFSIGALLLMKLAQMAAKYFSHVEIIEYHHNLKVDA
PSGTAIKTAELLSSIRENQPSAIQEEEKIPGSRGGDYRGIKIHSVRLPGLVAHQEVIFGGRGQSLTLRHDVYSRESYLDG
ILFALKKVLELDRFVFGLDELLF
>Mature_262_residues
ARIVMLGACGKMGREISKNLLMHSEHELVGFVDVVNVGQDFGEILGISRLGKTVEDNLKEVILKTNPEIVLDFSRASGAF
TNILIALENKVRVVSGTTGFSQEQIKKIEDVSNANNLGCIIAPNFSIGALLLMKLAQMAAKYFSHVEIIEYHHNLKVDAP
SGTAIKTAELLSSIRENQPSAIQEEEKIPGSRGGDYRGIKIHSVRLPGLVAHQEVIFGGRGQSLTLRHDVYSRESYLDGI
LFALKKVLELDRFVFGLDELLF

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=276, Percent_Identity=28.2608695652174, Blast_Score=100, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CARHZ (Q3ACY8)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359996.1
- ProteinModelPortal:   Q3ACY8
- SMR:   Q3ACY8
- STRING:   Q3ACY8
- GeneID:   3727402
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_1151
- NMPDR:   fig|246194.3.peg.1197
- TIGR:   CHY_1151
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   HRSVPEF
- BioCyc:   CHYD246194:CHY_1151-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28960; Mature: 28829

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIVMLGACGKMGREISKNLLMHSEHELVGFVDVVNVGQDFGEILGISRLGKTVEDNLK
CCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
EVILKTNPEIVLDFSRASGAFTNILIALENKVRVVSGTTGFSQEQIKKIEDVSNANNLGC
HHHHCCCCCEEEEECCCCCCHHHEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCEE
IIAPNFSIGALLLMKLAQMAAKYFSHVEIIEYHHNLKVDAPSGTAIKTAELLSSIRENQP
EEECCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCHHHHHHHHHHHCCCC
SAIQEEEKIPGSRGGDYRGIKIHSVRLPGLVAHQEVIFGGRGQSLTLRHDVYSRESYLDG
CCHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHEECCCCCEEEEEHHHHHHHHHHHH
ILFALKKVLELDRFVFGLDELLF
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARIVMLGACGKMGREISKNLLMHSEHELVGFVDVVNVGQDFGEILGISRLGKTVEDNLK
CEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
EVILKTNPEIVLDFSRASGAFTNILIALENKVRVVSGTTGFSQEQIKKIEDVSNANNLGC
HHHHCCCCCEEEEECCCCCCHHHEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCEE
IIAPNFSIGALLLMKLAQMAAKYFSHVEIIEYHHNLKVDAPSGTAIKTAELLSSIRENQP
EEECCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCHHHHHHHHHHHCCCC
SAIQEEEKIPGSRGGDYRGIKIHSVRLPGLVAHQEVIFGGRGQSLTLRHDVYSRESYLDG
CCHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHEECCCCCEEEEEHHHHHHHHHHHH
ILFALKKVLELDRFVFGLDELLF
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA