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The map label for this gene is ftsK [H]

Identifier: 78043164

GI number: 78043164

Start: 1031875

End: 1034079

Strand: Direct

Name: ftsK [H]

Synonym: CHY_1159

Alternate gene names: 78043164

Gene position: 1031875-1034079 (Clockwise)

Preceding gene: 78045214

Following gene: 78044905

Centisome position: 42.97

GC content: 42.22

Gene sequence:

>2205_bases
ATGGCAAAATACAAGAATACCAAGCAGAAAAATAAAAAAAGTTTTACCGGTGAATTGTTGGGAATTTTTTTAATGCTCTT
GGGAATGATTGGAGTCGTCAGTATTTTCTCGGATAAAACCGGCTCGATAGGATTGTTTTTCCGGCACTGGTTTACCGTTT
TTGCCGGTCAGGGGAGTTTTCTTTTACCATTAATTATTTTTGCTATTGGTTTTAAACTTTCTTTTGGTCATACTATTAAA
CACTTTGGTAAAAAAGAAGCGGGTTTACTTGTCCTCGTGGCAGCATTTTTGATTTTTTTAACGATAAAACTACCGTTAAG
CGTAATGTTTACCATGGCCTGGCAGGGTGACGGGGGAGGAGTAATTGGGGCGCTCCTAACTTATGGTGCCTTAAAATCTC
TGGGATTAGTAGGCACCTACCTTTTGCTCCTAACCCTTATTTTAATTGGATTTTTACTAATTTTGGATTTATCTTTTAAA
GAATTTATGCAAAATCTCATTGGCGGTCTGAATAAAATAAAGGCTTTTGTGGTGGAAAGCATCTTTCCGTTGTTTATTGA
GGAAGAAGAACTCAAGCCCAAAAAGCAAAGAAAAGAGCCCGTAATTATTGAGATGCCGCCACCGCCTGAACCTGTTTTTA
ATTTTCAATCGGAAAGCTTTCCGGTCCATGTAGAGGCAGAAGAAAGGGCTGCCCAAAAGGAGAAAGAAAATAAGAAAACC
ATAAAGGAAAACGACGAAAATATAACTTCCTTTGAACAGCTAAGTCTTAAAGATTTTGAAAAGTACCAACTGCCACCAAT
ATCTCTGTTAAATCGGCCTAAATCATCCCGCAATCAAATGAATCGGGATATTTCCGAGAATATCAAAATCCTGGAAGAAA
CCCTTGAAAGTTTTGGGGTTCAAGCCACTGTTAAGGAAGTTTCCTGCGGACCGGCGATAACCCGCTATGAATTGGAACCT
GCCCCAGGGGTTAAGGTTAGTAAGATAGTAAGCTTAGCTGACGATATTGCTTTAAAATTAGCGGCAGCGGATGTCAGAAT
TGAAGCGCCAATTCCAGGAAAAGCCGCGGTTGGAATTGAAGTTCCCAACAAAGAAATAAATATGGTGGTATTAAGAGAAA
TTATCGAAACTCCTGAATTTCAGAATCAAGCTTCACCCCTTGCTTTTGCCCTGGGCAAGGATATTGCCGGTAAACCAATT
GTGGCCGATCTCCAAAAAATGCCTCATTTACTCATTGCTGGAGCAACAGGATCGGGGAAAAGTGTTTGTTTAAATACCCT
GATTTCCAGCATTTTATTCCGGGCAACTCCACAGGAAGTAAAGTTTCTGATGATCGACCCGAAAATGGTCGAGCTGGTTA
CTTTTAACGGCATTCCCCATTTAATTAGCCCGGTAGTTACCAATGCCAAAAAAGCAGCCATTTCTCTCCGCTGGGCTGTG
AGAGAAATGGAGCGGCGCTATGAACTTTTTGCCAAGTACGGAGTTCGGGATATAACGCGCTTTAACAGCTTAGTTTTAAC
TAAAGGTGGCGAGGATTTAAGTTATTTGCCTTACATCGTTATTATTATTGATGAGCTGGCCGATTTAATGATGGTTTCTC
CAGCAGAAGTGGAGGATTCTATCTGCCGGTTAGCACAAATGGCGCGAGCTGCCGGGATGCATTTGGTTGTAGCAACTCAA
CGTCCTTCGGTGGACGTAATAACCGGTTTAATAAAAGCCAATATTCCTTCACGGATATCGTTCGCGGTTTCCTCGCAGAC
CGATTCCCGTACTATCTTGGACATGGCTGGTGCGGAAAAACTTTTAGGAAAAGGAGATATGCTGTTTTTTCCGGTTGGCG
CCTCCAAACCCATTCGCGTTCAAGGAGCTTACATGTCCGATAAAGAAGTGGAAGCGGTGGTGGAGTTTTGGAAAAAACAG
GGGGACCCCGAATTTTCGTCCGAGTTCGAGCAGGAACTGGATGTCGAAGAAGATTCACAGTTGGAAGAAGACGAGTTATT
GCCGCAGGCGGTGAAAATTGTCATGGATGCCGGGCATGCCTCGATTTCCCTTCTCCAAAGACGTCTTAGAATTGGATATG
CCCGGGCAGCTCGTTTAATTGACCAAATGGAAAGAAAAGGAATTGTTGGGGGCTATGAAGGAAGTAAACCGCGGTCTGTG
TTAATTTCATACGAACAATATAAAGAAATGTTTAAGGACCTTTAA

Upstream 100 bases:

>100_bases
GTTAACCTGGTTTTCCTATTACGTCTGGATTTTGGGAGTAACAATTTTGGTGTTACAGGCGGCAGGTAAATTTTAACCTG
CCGCTTTTTGGAGGGATTGA

Downstream 100 bases:

>100_bases
AGGAAAAAACCTTTAAAGGTCCTTTTTTTGTATAAACTTACCGTAAAATAAGAAAACTATGATTACAGGTGGTGAGAAAA
TGACAAAAACTAAAACAAAA

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 734; Mature: 733

Protein sequence:

>734_residues
MAKYKNTKQKNKKSFTGELLGIFLMLLGMIGVVSIFSDKTGSIGLFFRHWFTVFAGQGSFLLPLIIFAIGFKLSFGHTIK
HFGKKEAGLLVLVAAFLIFLTIKLPLSVMFTMAWQGDGGGVIGALLTYGALKSLGLVGTYLLLLTLILIGFLLILDLSFK
EFMQNLIGGLNKIKAFVVESIFPLFIEEEELKPKKQRKEPVIIEMPPPPEPVFNFQSESFPVHVEAEERAAQKEKENKKT
IKENDENITSFEQLSLKDFEKYQLPPISLLNRPKSSRNQMNRDISENIKILEETLESFGVQATVKEVSCGPAITRYELEP
APGVKVSKIVSLADDIALKLAAADVRIEAPIPGKAAVGIEVPNKEINMVVLREIIETPEFQNQASPLAFALGKDIAGKPI
VADLQKMPHLLIAGATGSGKSVCLNTLISSILFRATPQEVKFLMIDPKMVELVTFNGIPHLISPVVTNAKKAAISLRWAV
REMERRYELFAKYGVRDITRFNSLVLTKGGEDLSYLPYIVIIIDELADLMMVSPAEVEDSICRLAQMARAAGMHLVVATQ
RPSVDVITGLIKANIPSRISFAVSSQTDSRTILDMAGAEKLLGKGDMLFFPVGASKPIRVQGAYMSDKEVEAVVEFWKKQ
GDPEFSSEFEQELDVEEDSQLEEDELLPQAVKIVMDAGHASISLLQRRLRIGYARAARLIDQMERKGIVGGYEGSKPRSV
LISYEQYKEMFKDL

Sequences:

>Translated_734_residues
MAKYKNTKQKNKKSFTGELLGIFLMLLGMIGVVSIFSDKTGSIGLFFRHWFTVFAGQGSFLLPLIIFAIGFKLSFGHTIK
HFGKKEAGLLVLVAAFLIFLTIKLPLSVMFTMAWQGDGGGVIGALLTYGALKSLGLVGTYLLLLTLILIGFLLILDLSFK
EFMQNLIGGLNKIKAFVVESIFPLFIEEEELKPKKQRKEPVIIEMPPPPEPVFNFQSESFPVHVEAEERAAQKEKENKKT
IKENDENITSFEQLSLKDFEKYQLPPISLLNRPKSSRNQMNRDISENIKILEETLESFGVQATVKEVSCGPAITRYELEP
APGVKVSKIVSLADDIALKLAAADVRIEAPIPGKAAVGIEVPNKEINMVVLREIIETPEFQNQASPLAFALGKDIAGKPI
VADLQKMPHLLIAGATGSGKSVCLNTLISSILFRATPQEVKFLMIDPKMVELVTFNGIPHLISPVVTNAKKAAISLRWAV
REMERRYELFAKYGVRDITRFNSLVLTKGGEDLSYLPYIVIIIDELADLMMVSPAEVEDSICRLAQMARAAGMHLVVATQ
RPSVDVITGLIKANIPSRISFAVSSQTDSRTILDMAGAEKLLGKGDMLFFPVGASKPIRVQGAYMSDKEVEAVVEFWKKQ
GDPEFSSEFEQELDVEEDSQLEEDELLPQAVKIVMDAGHASISLLQRRLRIGYARAARLIDQMERKGIVGGYEGSKPRSV
LISYEQYKEMFKDL
>Mature_733_residues
AKYKNTKQKNKKSFTGELLGIFLMLLGMIGVVSIFSDKTGSIGLFFRHWFTVFAGQGSFLLPLIIFAIGFKLSFGHTIKH
FGKKEAGLLVLVAAFLIFLTIKLPLSVMFTMAWQGDGGGVIGALLTYGALKSLGLVGTYLLLLTLILIGFLLILDLSFKE
FMQNLIGGLNKIKAFVVESIFPLFIEEEELKPKKQRKEPVIIEMPPPPEPVFNFQSESFPVHVEAEERAAQKEKENKKTI
KENDENITSFEQLSLKDFEKYQLPPISLLNRPKSSRNQMNRDISENIKILEETLESFGVQATVKEVSCGPAITRYELEPA
PGVKVSKIVSLADDIALKLAAADVRIEAPIPGKAAVGIEVPNKEINMVVLREIIETPEFQNQASPLAFALGKDIAGKPIV
ADLQKMPHLLIAGATGSGKSVCLNTLISSILFRATPQEVKFLMIDPKMVELVTFNGIPHLISPVVTNAKKAAISLRWAVR
EMERRYELFAKYGVRDITRFNSLVLTKGGEDLSYLPYIVIIIDELADLMMVSPAEVEDSICRLAQMARAAGMHLVVATQR
PSVDVITGLIKANIPSRISFAVSSQTDSRTILDMAGAEKLLGKGDMLFFPVGASKPIRVQGAYMSDKEVEAVVEFWKKQG
DPEFSSEFEQELDVEEDSQLEEDELLPQAVKIVMDAGHASISLLQRRLRIGYARAARLIDQMERKGIVGGYEGSKPRSVL
ISYEQYKEMFKDL

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=481, Percent_Identity=49.4802494802495, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 81366; Mature: 81235

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYKNTKQKNKKSFTGELLGIFLMLLGMIGVVSIFSDKTGSIGLFFRHWFTVFAGQGSF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCH
LLPLIIFAIGFKLSFGHTIKHFGKKEAGLLVLVAAFLIFLTIKLPLSVMFTMAWQGDGGG
HHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCH
VIGALLTYGALKSLGLVGTYLLLLTLILIGFLLILDLSFKEFMQNLIGGLNKIKAFVVES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IFPLFIEEEELKPKKQRKEPVIIEMPPPPEPVFNFQSESFPVHVEAEERAAQKEKENKKT
HHHHHCCHHHCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
IKENDENITSFEQLSLKDFEKYQLPPISLLNRPKSSRNQMNRDISENIKILEETLESFGV
HHCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCC
QATVKEVSCGPAITRYELEPAPGVKVSKIVSLADDIALKLAAADVRIEAPIPGKAAVGIE
EEEEHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEECEEEECCCCCCEEEEEE
VPNKEINMVVLREIIETPEFQNQASPLAFALGKDIAGKPIVADLQKMPHLLIAGATGSGK
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCEEEEECCCCCH
SVCLNTLISSILFRATPQEVKFLMIDPKMVELVTFNGIPHLISPVVTNAKKAAISLRWAV
HHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHH
REMERRYELFAKYGVRDITRFNSLVLTKGGEDLSYLPYIVIIIDELADLMMVSPAEVEDS
HHHHHHHHHHHHHCHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
ICRLAQMARAAGMHLVVATQRPSVDVITGLIKANIPSRISFAVSSQTDSRTILDMAGAEK
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHCHHH
LLGKGDMLFFPVGASKPIRVQGAYMSDKEVEAVVEFWKKQGDPEFSSEFEQELDVEEDSQ
HHCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
LEEDELLPQAVKIVMDAGHASISLLQRRLRIGYARAARLIDQMERKGIVGGYEGSKPRSV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHE
LISYEQYKEMFKDL
EEEHHHHHHHHHCC
>Mature Secondary Structure 
AKYKNTKQKNKKSFTGELLGIFLMLLGMIGVVSIFSDKTGSIGLFFRHWFTVFAGQGSF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCH
LLPLIIFAIGFKLSFGHTIKHFGKKEAGLLVLVAAFLIFLTIKLPLSVMFTMAWQGDGGG
HHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCH
VIGALLTYGALKSLGLVGTYLLLLTLILIGFLLILDLSFKEFMQNLIGGLNKIKAFVVES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IFPLFIEEEELKPKKQRKEPVIIEMPPPPEPVFNFQSESFPVHVEAEERAAQKEKENKKT
HHHHHCCHHHCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
IKENDENITSFEQLSLKDFEKYQLPPISLLNRPKSSRNQMNRDISENIKILEETLESFGV
HHCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCC
QATVKEVSCGPAITRYELEPAPGVKVSKIVSLADDIALKLAAADVRIEAPIPGKAAVGIE
EEEEHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEECEEEECCCCCCEEEEEE
VPNKEINMVVLREIIETPEFQNQASPLAFALGKDIAGKPIVADLQKMPHLLIAGATGSGK
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCEEEEECCCCCH
SVCLNTLISSILFRATPQEVKFLMIDPKMVELVTFNGIPHLISPVVTNAKKAAISLRWAV
HHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHH
REMERRYELFAKYGVRDITRFNSLVLTKGGEDLSYLPYIVIIIDELADLMMVSPAEVEDS
HHHHHHHHHHHHHCHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
ICRLAQMARAAGMHLVVATQRPSVDVITGLIKANIPSRISFAVSSQTDSRTILDMAGAEK
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHCHHH
LLGKGDMLFFPVGASKPIRVQGAYMSDKEVEAVVEFWKKQGDPEFSSEFEQELDVEEDSQ
HHCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
LEEDELLPQAVKIVMDAGHASISLLQRRLRIGYARAARLIDQMERKGIVGGYEGSKPRSV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHE
LISYEQYKEMFKDL
EEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]