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The map label for this gene is emrY [C]

Identifier: 77761104

GI number: 77761104

Start: 805999

End: 807648

Strand: Reverse

Name: emrY [C]

Synonym: XC_0674

Alternate gene names: 77761104

Gene position: 807648-805999 (Counterclockwise)

Preceding gene: 66767025

Following gene: 77761103

Centisome position: 15.69

GC content: 66.36

Gene sequence:

>1650_bases
GTGCGCGACAAGTACGTTCAGCGCGACTGGCAGCCCCATGAGAAGCCCACCCTGCCCGGGTCGGCCTCCACGCCGCTGCA
CCCGACCCGGCGACGCATCCAGTACGGCCTGGTCGGCGTGGTGGTGGCGCTGACCGGTGGGCTGAGCAATGCGCTGGTCA
CTGCCAACCTGCCCTATCTGCAAGGCACGCTGGGGGCGTACGCCACTGAAATGGCCTGGCTGCCGGCCGCCTACGTGATG
ACCAACATGTCGGCCAACCTGCTGCTGGTGAAGTTCCGCCAGCAGTTCGGGCTGCGGCGGTTCACCGAGATCTTCCTGGC
GCTGTATGCGGTGATTGCCTTCGCGCACCTGTTCGTGCACAGCCTGAGTTCGGCCATCACCGTGCGGGCCGCCCACGGGC
TGGTGGGCGCGGCGCTCAGCTCGTTGGGGCTGTACTACGTGATCCAGGCGTTCCCGGCCAAATACCGGCTCAAGGCGGTG
GTGACCGGGCTGGGGCTCACCCAGCTGGCACTGCCACTGGCGCGGGTGTTTTCCACCGACCTGCTGGAATTTGGCGAATG
GCAGGGGCTGTATCTGTTCGAATTCGGCCTGGCGGTGTTTGCGCTGGCCTGCGTGCTGGCGCTCAAGCTGCCGCCGAGCG
ACCGGTACCGCGTATTCGAGCCGTTGGACTTCCTCACCTTCAGCCTGTTCGCTGCCGGCGCGGCGGGATTGGCCGCGGTG
CTCTCGCTGGGCCGGCTGCTGTGGTGGACCAGCACGCCGTGGCTGGGCGTGGTGCTGGCGGCCTCCATCGTGCTGCTGTG
CGCGGCCGCATGGATCGAACACAACCGCCGCAATCCGATGATCAACACGCGCTGGCTGGCCAGTGCCGACATGCTGCGCC
TGGGCCTGGCAATCCTGCTGATCCGCCTGGTGCTGTCCGAACAGAGCACCGGTGCGATCGGCTTCTTCCAGACTCTGGGG
TTGGCGAACACCCAATTGCAGACCTTGTTCGCGCTGATGTTGCTGGGCGCGGTGGTGGGCGTGGTGGCCAGTGCCTTGCT
GATCAATCCGGCGCGCATTGCAGAGCACCTGATCATCGCGGTGGCGGCGATCTGCATCGGCTGCTTCATGGATGCGCGCG
CCACCAGCCTGACCCGGCCGGAACAGATGTATGTCAGCCAGTTTCTGCTGGCGTTCGGCAGCACCTTCTTCGTGGGCCCG
GCGATGGTGGCCGGCATCGGCCGCGTAGTCACCCAGCCGCGCAACCTGATCAGTTTCATCGTGTTGTTCGGCATGGCGCA
GAACATGGGCGGCCTGCTCGGCAGCGCGCTGCTGGGCACGCTGCAGGTGGTGCGCGAGAAATATCACTCCAGCCAATTGG
TCGAGCACCTGGTGCTCACCGACCCACAGGTGGCCGCGCGCGTGCAGGCCTATGCCAGCGTGTACGGGCGCGCGATCGGC
GACCCGGCCCTGCGCCAGGCGCAAGGCGTGCGTGCACTGGGCACGGTGGCCACCCGCGAAGCCAACGTACTGGCCTATAA
CGATGTGTTCCTGTTGATCGGCTGCATTGCCATTGCCACCGGGTTGTGGATTCTCTCCGTGCTGGTGTGGCGCCGTTATC
TGCGCCCGCCGGTTGCCCCCTCTCCTTCTGTTCCGACTGCGCGCCCATGA

Upstream 100 bases:

>100_bases
GAGATTCGCTCATGGGCGGATTATCGCACTGCTGACGCCACCATGACCGCAACGGGACCACAATCGCGGCTCTTCCTGCG
ACGGCCCCAGCGAGCACTTG

Downstream 100 bases:

>100_bases
ATACACCTGCCGACACCGCTCCAACCGCCGCACAGAGACGGCGTCGCCGTCGCCGCCGTCTGTATGGCGTGCTCGGGTTC
GGTGGGCTTGCGCTGATCGG

Product: MFS transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Facilitator Superfamily Protein; Transport Protein Transmembrane; Facilitator Superfamily Transporter; MFS Drug Efflux Transporter RmrB; Transporter Facilitator Family; Multidrug Resistance Protein B; Transmembrane Efflux Pump Protein; Tat Pathway Signal Sequence Domain Protein; EmrB/QacA Family Drug Resistance Transporter; MFS Drug Efflux Transporter; MFS Permease; Efflux Protein; Facilitator Superfamily Transporter Protein; MFS Family Transporter; HlyD Family Protein; Facilitator Family Transporter; Facilitator Superfamily Permease

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MRDKYVQRDWQPHEKPTLPGSASTPLHPTRRRIQYGLVGVVVALTGGLSNALVTANLPYLQGTLGAYATEMAWLPAAYVM
TNMSANLLLVKFRQQFGLRRFTEIFLALYAVIAFAHLFVHSLSSAITVRAAHGLVGAALSSLGLYYVIQAFPAKYRLKAV
VTGLGLTQLALPLARVFSTDLLEFGEWQGLYLFEFGLAVFALACVLALKLPPSDRYRVFEPLDFLTFSLFAAGAAGLAAV
LSLGRLLWWTSTPWLGVVLAASIVLLCAAAWIEHNRRNPMINTRWLASADMLRLGLAILLIRLVLSEQSTGAIGFFQTLG
LANTQLQTLFALMLLGAVVGVVASALLINPARIAEHLIIAVAAICIGCFMDARATSLTRPEQMYVSQFLLAFGSTFFVGP
AMVAGIGRVVTQPRNLISFIVLFGMAQNMGGLLGSALLGTLQVVREKYHSSQLVEHLVLTDPQVAARVQAYASVYGRAIG
DPALRQAQGVRALGTVATREANVLAYNDVFLLIGCIAIATGLWILSVLVWRRYLRPPVAPSPSVPTARP

Sequences:

>Translated_549_residues
MRDKYVQRDWQPHEKPTLPGSASTPLHPTRRRIQYGLVGVVVALTGGLSNALVTANLPYLQGTLGAYATEMAWLPAAYVM
TNMSANLLLVKFRQQFGLRRFTEIFLALYAVIAFAHLFVHSLSSAITVRAAHGLVGAALSSLGLYYVIQAFPAKYRLKAV
VTGLGLTQLALPLARVFSTDLLEFGEWQGLYLFEFGLAVFALACVLALKLPPSDRYRVFEPLDFLTFSLFAAGAAGLAAV
LSLGRLLWWTSTPWLGVVLAASIVLLCAAAWIEHNRRNPMINTRWLASADMLRLGLAILLIRLVLSEQSTGAIGFFQTLG
LANTQLQTLFALMLLGAVVGVVASALLINPARIAEHLIIAVAAICIGCFMDARATSLTRPEQMYVSQFLLAFGSTFFVGP
AMVAGIGRVVTQPRNLISFIVLFGMAQNMGGLLGSALLGTLQVVREKYHSSQLVEHLVLTDPQVAARVQAYASVYGRAIG
DPALRQAQGVRALGTVATREANVLAYNDVFLLIGCIAIATGLWILSVLVWRRYLRPPVAPSPSVPTARP
>Mature_549_residues
MRDKYVQRDWQPHEKPTLPGSASTPLHPTRRRIQYGLVGVVVALTGGLSNALVTANLPYLQGTLGAYATEMAWLPAAYVM
TNMSANLLLVKFRQQFGLRRFTEIFLALYAVIAFAHLFVHSLSSAITVRAAHGLVGAALSSLGLYYVIQAFPAKYRLKAV
VTGLGLTQLALPLARVFSTDLLEFGEWQGLYLFEFGLAVFALACVLALKLPPSDRYRVFEPLDFLTFSLFAAGAAGLAAV
LSLGRLLWWTSTPWLGVVLAASIVLLCAAAWIEHNRRNPMINTRWLASADMLRLGLAILLIRLVLSEQSTGAIGFFQTLG
LANTQLQTLFALMLLGAVVGVVASALLINPARIAEHLIIAVAAICIGCFMDARATSLTRPEQMYVSQFLLAFGSTFFVGP
AMVAGIGRVVTQPRNLISFIVLFGMAQNMGGLLGSALLGTLQVVREKYHSSQLVEHLVLTDPQVAARVQAYASVYGRAIG
DPALRQAQGVRALGTVATREANVLAYNDVFLLIGCIAIATGLWILSVLVWRRYLRPPVAPSPSVPTARP

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 59405; Mature: 59405

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCC
>Mature Secondary Structure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CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA