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The map label for this gene is 77748726

Identifier: 77748726

GI number: 77748726

Start: 4198940

End: 4200811

Strand: Reverse

Name: 77748726

Synonym: XAC3547

Alternate gene names: NA

Gene position: 4200811-4198940 (Counterclockwise)

Preceding gene: 77748727

Following gene: 21244271

Centisome position: 81.17

GC content: 66.56

Gene sequence:

>1872_bases
GTGATCCAGAGCTCTTCTACGCAGGTCCTTGTGCTTGCCTGCTGTGTCCTGGCTGCGTCGTGCAGTACAGCGTTGGCCGC
CAACGCCGATGCGGCAGCGGCCAGTGCCCAACGCCAACAGGCCATGGCCAATGCGCCGGTCGACAGAATCATCGTCCGCT
ACCGCAGCGGGCAGGTCGGCACCGCGCGCGATATCGGCCGCACTGCCTCGGCGACAGTCGGTGCGGCCGCTTCGCGCGCA
TCCGTCCGTCTTGCGCCTGCCGCACGCACCGGTGCCACCGCAGCGCCAACCTATCTGCGCACGCTTGCCGCGGGCGGCGA
ATTGATCAAATTGCCGGCCCAGCTCAGTCGCGCCGATGCCGACCGTCTTGTGCAGGAATTGAGCGCAGACCCAGACGTCG
AATCGGCGCAGGTGGATCTGCGCATGTATCCGCTGCAAACCAGCGGCGCATTGCCGAACGATCCGCTGCTGCAAACCAAT
CAATGGCATCTCATCGACCCGGTGGGTGGCATCGACGTCGCGCAAGCCTGGAAAACAACGCAGGGCGAAGGCGTCGTAGT
GGCGGTACTGGATACCGGCATCCTGCCCGATCACCCGGATCTGGCCGGCAATCTGCTCACCGGCTACGACTTCATCACCG
ATCCGTTCTTCTCGCGTCGCGCCACGGCCGAGCGTGTGCCCGGCGCACTGGACCTCGGCGATTGGATTGCCGAAGACGGC
GACTGCGGGCTGTTCTCGGTGGCCAGCGACAGCAGCTGGCACGGCACGCACGTGGCCGGCACGGTTGCCGAAGCCACCAA
CAACGGCATTGGCGGGGCAGGCGTCGCCTACAGGGCGAAAGTGCTGCCGGTGCGCGTGCTCGGGCACTGCGGCGGGCAAT
TCTCCGACATCTCCGATGCCATCGTCTGGGCGTCCGGCGGTCACGTCGATGGCGTACCGGACAACCGCGATCCGGCCGAA
GTGATCAACCTGAGCCTGGGCGGTGGCGGCGCATGCGGTTCGGCGATGCAGGCCGCGATCAATGGTGCAGTGGCGCGCGG
CACCACCGTGGTGGTGGCGGCGGGTAATTCAACTGCCGATGTATCGACGACTGCTCCCGCCAACTGCGCCAATGTGATTG
CCGTTGCCGCCACGCGCGCCACCGGTGCGCTCGCCGATTACAGCAATTTCGGCCGTCAGATCGATCTGGCCGGCCCGGGT
GGCAGTTCGATGTTCTTCGCCACCAACGACGGCCCGATTCGCAGCTTCGTTTGGCAAACCCTCTACACCGGCAAAACCAC
GCCGACCTCCGGGCAGTTCACCTATGGCGGCAGCGACTTCGCAGGCACCTCGATGGCATCGCCGCATGTGGCCGGCACCG
CCGCATTGGTGCAGAGCGCATTGATCGCCGACGGCAAACCGCCGTTGTCGCCGGCCGCGATGGAAAATTTGCTCAAGCGC
ACTGCGCGCGCATTCCCGGTGTCGATTCCGGTGGCAACGCCGGCCGGCTCCGGCATCGTGGATGCCGGAGCCGCGGTTGC
CCGCGCGTTACGTCGCTGCGATCGGGGCGATGTGGGGTGCCAGGTGGATGCGCAGCCACTGCGTAATGGCGTGGTCCAGA
GCGGCATCTCCAATCTGTCGGGCGATGCGGGCGTGTTCACGTTCCAAGCGCAGGCGGGTGCGGTGCTGAGTTTCATCAGC
TTCGGCGGCAGCGGCCAGGCGGAGTTGTACGTGGCATTCGGACGCGAGCCCACTGCCACCGACAACGACGGCGCGTCCAC
GCGTCGCGGCACCAGCCAGACGGTGCGCTTCACCGCGCCGCGTGCCGGCACCTACATCCTCAAGCTGGAAGGCAGCGGTT
TCGACGCGGTGAACCTGCTGGCGCGCCAATGA

Upstream 100 bases:

>100_bases
GCAGCACGACCACGCGGTTGCATGCATTCCCGCCGCCCATTGCCGGGCGGCGCGCTTTCTTCGTCATGCCCTTTCGCACT
CACCTCGAAGGAATCCCATC

Downstream 100 bases:

>100_bases
TCCGACACGCAGTCGTCGGTTCGGCAGGATCGTCATTTCCTTGGCGGTGAACGCCTGAAACACGGCTGCTCCGCGCGCCG
ATGGACGGCGCATGCGGGCT

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MIQSSSTQVLVLACCVLAASCSTALAANADAAAASAQRQQAMANAPVDRIIVRYRSGQVGTARDIGRTASATVGAAASRA
SVRLAPAARTGATAAPTYLRTLAAGGELIKLPAQLSRADADRLVQELSADPDVESAQVDLRMYPLQTSGALPNDPLLQTN
QWHLIDPVGGIDVAQAWKTTQGEGVVVAVLDTGILPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWIAEDG
DCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGQFSDISDAIVWASGGHVDGVPDNRDPAE
VINLSLGGGGACGSAMQAAINGAVARGTTVVVAAGNSTADVSTTAPANCANVIAVAATRATGALADYSNFGRQIDLAGPG
GSSMFFATNDGPIRSFVWQTLYTGKTTPTSGQFTYGGSDFAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMENLLKR
TARAFPVSIPVATPAGSGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGISNLSGDAGVFTFQAQAGAVLSFIS
FGGSGQAELYVAFGREPTATDNDGASTRRGTSQTVRFTAPRAGTYILKLEGSGFDAVNLLARQ

Sequences:

>Translated_623_residues
MIQSSSTQVLVLACCVLAASCSTALAANADAAAASAQRQQAMANAPVDRIIVRYRSGQVGTARDIGRTASATVGAAASRA
SVRLAPAARTGATAAPTYLRTLAAGGELIKLPAQLSRADADRLVQELSADPDVESAQVDLRMYPLQTSGALPNDPLLQTN
QWHLIDPVGGIDVAQAWKTTQGEGVVVAVLDTGILPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWIAEDG
DCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGQFSDISDAIVWASGGHVDGVPDNRDPAE
VINLSLGGGGACGSAMQAAINGAVARGTTVVVAAGNSTADVSTTAPANCANVIAVAATRATGALADYSNFGRQIDLAGPG
GSSMFFATNDGPIRSFVWQTLYTGKTTPTSGQFTYGGSDFAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMENLLKR
TARAFPVSIPVATPAGSGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGISNLSGDAGVFTFQAQAGAVLSFIS
FGGSGQAELYVAFGREPTATDNDGASTRRGTSQTVRFTAPRAGTYILKLEGSGFDAVNLLARQ
>Mature_623_residues
MIQSSSTQVLVLACCVLAASCSTALAANADAAAASAQRQQAMANAPVDRIIVRYRSGQVGTARDIGRTASATVGAAASRA
SVRLAPAARTGATAAPTYLRTLAAGGELIKLPAQLSRADADRLVQELSADPDVESAQVDLRMYPLQTSGALPNDPLLQTN
QWHLIDPVGGIDVAQAWKTTQGEGVVVAVLDTGILPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWIAEDG
DCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGQFSDISDAIVWASGGHVDGVPDNRDPAE
VINLSLGGGGACGSAMQAAINGAVARGTTVVVAAGNSTADVSTTAPANCANVIAVAATRATGALADYSNFGRQIDLAGPG
GSSMFFATNDGPIRSFVWQTLYTGKTTPTSGQFTYGGSDFAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMENLLKR
TARAFPVSIPVATPAGSGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGISNLSGDAGVFTFQAQAGAVLSFIS
FGGSGQAELYVAFGREPTATDNDGASTRRGTSQTVRFTAPRAGTYILKLEGSGFDAVNLLARQ

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI76443679, Length=177, Percent_Identity=32.2033898305085, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324576, Length=374, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320775, Length=330, Percent_Identity=28.4848484848485, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319893, Length=346, Percent_Identity=26.5895953757225, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 63273; Mature: 63273

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQSSSTQVLVLACCVLAASCSTALAANADAAAASAQRQQAMANAPVDRIIVRYRSGQVG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHEEEEECCCCCC
TARDIGRTASATVGAAASRASVRLAPAARTGATAAPTYLRTLAAGGELIKLPAQLSRADA
CHHHCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCEEECCHHHHHCHH
DRLVQELSADPDVESAQVDLRMYPLQTSGALPNDPLLQTNQWHLIDPVGGIDVAQAWKTT
HHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCHHHHHHCCC
QGEGVVVAVLDTGILPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWIAEDG
CCCCEEEEEEECCCCCCCCCCCCCHHCCCHHHCCCHHHHCCHHHHCCCCCCCHHHHCCCC
DCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGQFSDISDA
CCCEEEECCCCCCCCCEEEEEHHHHCCCCCCCCCCEEEEEEEEEEEEHHCCCCCCCCCCE
IVWASGGHVDGVPDNRDPAEVINLSLGGGGACGSAMQAAINGAVARGTTVVVAAGNSTAD
EEEECCCCCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHCCCEECCCEEEEECCCCCCC
VSTTAPANCANVIAVAATRATGALADYSNFGRQIDLAGPGGSSMFFATNDGPIRSFVWQT
CCCCCCCCHHHEEEEEEHHCCCCHHHHHHCCCEEEECCCCCCEEEEEECCCHHHHHHHHH
LYTGKTTPTSGQFTYGGSDFAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMENLLKR
HHCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
TARAFPVSIPVATPAGSGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGISNLS
HHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHCC
GDAGVFTFQAQAGAVLSFISFGGSGQAELYVAFGREPTATDNDGASTRRGTSQTVRFTAP
CCCCEEEEECCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECC
RAGTYILKLEGSGFDAVNLLARQ
CCCEEEEEECCCCCCHHHHHHCC
>Mature Secondary Structure
MIQSSSTQVLVLACCVLAASCSTALAANADAAAASAQRQQAMANAPVDRIIVRYRSGQVG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHEEEEECCCCCC
TARDIGRTASATVGAAASRASVRLAPAARTGATAAPTYLRTLAAGGELIKLPAQLSRADA
CHHHCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCEEECCHHHHHCHH
DRLVQELSADPDVESAQVDLRMYPLQTSGALPNDPLLQTNQWHLIDPVGGIDVAQAWKTT
HHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCHHHHHHCCC
QGEGVVVAVLDTGILPDHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWIAEDG
CCCCEEEEEEECCCCCCCCCCCCCHHCCCHHHCCCHHHHCCHHHHCCCCCCCHHHHCCCC
DCGLFSVASDSSWHGTHVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCGGQFSDISDA
CCCEEEECCCCCCCCCEEEEEHHHHCCCCCCCCCCEEEEEEEEEEEEHHCCCCCCCCCCE
IVWASGGHVDGVPDNRDPAEVINLSLGGGGACGSAMQAAINGAVARGTTVVVAAGNSTAD
EEEECCCCCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHCCCEECCCEEEEECCCCCCC
VSTTAPANCANVIAVAATRATGALADYSNFGRQIDLAGPGGSSMFFATNDGPIRSFVWQT
CCCCCCCCHHHEEEEEEHHCCCCHHHHHHCCCEEEECCCCCCEEEEEECCCHHHHHHHHH
LYTGKTTPTSGQFTYGGSDFAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMENLLKR
HHCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
TARAFPVSIPVATPAGSGIVDAGAAVARALRRCDRGDVGCQVDAQPLRNGVVQSGISNLS
HHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHCC
GDAGVFTFQAQAGAVLSFISFGGSGQAELYVAFGREPTATDNDGASTRRGTSQTVRFTAP
CCCCEEEEECCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECC
RAGTYILKLEGSGFDAVNLLARQ
CCCEEEEEECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]