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The map label for this gene is prpC [H]

Identifier: 77465493

GI number: 77465493

Start: 567643

End: 568389

Strand: Reverse

Name: prpC [H]

Synonym: RSP_3492

Alternate gene names: 77465493

Gene position: 568389-567643 (Counterclockwise)

Preceding gene: 77465495

Following gene: 77465492

Centisome position: 60.27

GC content: 72.96

Gene sequence:

>747_bases
ATGAAGGCGCCGACGACGGTCGTGCCCCGTGCCGGGCTGCGGGTCGAGGGCTGGGGCATCACCCACCGCGGCCACCGGCG
CGCGCGGAACGAGGATGCGATCCTGACCGACCCCGCGGGCCAGCTCTGGGCCGTGGCGGACGGGATGGGCGGCCACGGGC
AGGGCGATGTGGCGGCCGATATCGTGATCGACCATCTCGAGACGATCCCCGAGGGCGGCGAGCCCCGGCGGATGCTGGTG
GCGGGGCTCGAGGCTGCCAATGCCGCCATCCGCGCGCACGCGCGGAAGGCAGAGGTCGGGCAGATGGGGGCTACGGTCGT
GGCCCTGCTCATCGCCCGCACCACGGCCCATGTCGCCTGGGTGGGCGACAGCCGGGCCTATCTGTTGCGCGCGGGCCGCC
TGAGCGCGCTCACCCGCGATCACAGCGTCGTGCAGGCGCTTGTGGACGCAGGCCACCTCGATCCGGCCGCTGCCGCCCTC
CATCCCGAGGCGAACCTCGTCACCCGAGCGGTGGGGGCCTCCGATACGGTCGAGGTCGAGACGGTCGCGCTGGAGATCGC
AGCCGGCGACCGGCTTCTGCTCTGCTCGGACGGGCTCACCCATTGCGTGGCCGATCCCGTCCTTGAGGGGCATTTGGCGT
CGGCGGTGGGGCCTTACGAGTCCTGCCTCGCGCTCGTCCGCGCGGCGCTCGATGCGGGCGGGCCCGACAATGTCTCGGTG
GTGGTGGTTGACGTGGCGGAGGGCTGA

Upstream 100 bases:

>100_bases
AGGCTATCATGAACGCGCATTGGTTTCACCCATTTGGACCAGCCGCCATGACCCTGCCGGAAGTGCGACGGCCGCGCGTC
CCGCCCCGAGGGCCCGCGCG

Downstream 100 bases:

>100_bases
GCCATGCAGCGCGGCAGCCTCGCCGGGCCCCTGATCGTCGCCATCGGCCTCGTGGTGGCGGCGATGGCCTTCGCGGTGGT
GACGAGCCTTCTGCGCACGG

Product: protein phosphatase 2C-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKAPTTVVPRAGLRVEGWGITHRGHRRARNEDAILTDPAGQLWAVADGMGGHGQGDVAADIVIDHLETIPEGGEPRRMLV
AGLEAANAAIRAHARKAEVGQMGATVVALLIARTTAHVAWVGDSRAYLLRAGRLSALTRDHSVVQALVDAGHLDPAAAAL
HPEANLVTRAVGASDTVEVETVALEIAAGDRLLLCSDGLTHCVADPVLEGHLASAVGPYESCLALVRAALDAGGPDNVSV
VVVDVAEG

Sequences:

>Translated_248_residues
MKAPTTVVPRAGLRVEGWGITHRGHRRARNEDAILTDPAGQLWAVADGMGGHGQGDVAADIVIDHLETIPEGGEPRRMLV
AGLEAANAAIRAHARKAEVGQMGATVVALLIARTTAHVAWVGDSRAYLLRAGRLSALTRDHSVVQALVDAGHLDPAAAAL
HPEANLVTRAVGASDTVEVETVALEIAAGDRLLLCSDGLTHCVADPVLEGHLASAVGPYESCLALVRAALDAGGPDNVSV
VVVDVAEG
>Mature_248_residues
MKAPTTVVPRAGLRVEGWGITHRGHRRARNEDAILTDPAGQLWAVADGMGGHGQGDVAADIVIDHLETIPEGGEPRRMLV
AGLEAANAAIRAHARKAEVGQMGATVVALLIARTTAHVAWVGDSRAYLLRAGRLSALTRDHSVVQALVDAGHLDPAAAAL
HPEANLVTRAVGASDTVEVETVALEIAAGDRLLLCSDGLTHCVADPVLEGHLASAVGPYESCLALVRAALDAGGPDNVSV
VVVDVAEG

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 25532; Mature: 25532

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPTTVVPRAGLRVEGWGITHRGHRRARNEDAILTDPAGQLWAVADGMGGHGQGDVAAD
CCCCCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEECCCCCEEEEECCCCCCCCCCHHHH
IVIDHLETIPEGGEPRRMLVAGLEAANAAIRAHARKAEVGQMGATVVALLIARTTAHVAW
HHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
VGDSRAYLLRAGRLSALTRDHSVVQALVDAGHLDPAAAALHPEANLVTRAVGASDTVEVE
ECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHCCCCCCEEEE
TVALEIAAGDRLLLCSDGLTHCVADPVLEGHLASAVGPYESCLALVRAALDAGGPDNVSV
EEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEE
VVVDVAEG
EEEEECCC
>Mature Secondary Structure
MKAPTTVVPRAGLRVEGWGITHRGHRRARNEDAILTDPAGQLWAVADGMGGHGQGDVAAD
CCCCCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEECCCCCEEEEECCCCCCCCCCHHHH
IVIDHLETIPEGGEPRRMLVAGLEAANAAIRAHARKAEVGQMGATVVALLIARTTAHVAW
HHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
VGDSRAYLLRAGRLSALTRDHSVVQALVDAGHLDPAAAALHPEANLVTRAVGASDTVEVE
ECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHCCCCCCEEEE
TVALEIAAGDRLLLCSDGLTHCVADPVLEGHLASAVGPYESCLALVRAALDAGGPDNVSV
EEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEE
VVVDVAEG
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]