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The map label for this gene is ttdR [H]

Identifier: 77465387

GI number: 77465387

Start: 448482

End: 449429

Strand: Reverse

Name: ttdR [H]

Synonym: RSP_3385

Alternate gene names: 77465387

Gene position: 449429-448482 (Counterclockwise)

Preceding gene: 77465392

Following gene: 77465386

Centisome position: 47.66

GC content: 69.41

Gene sequence:

>948_bases
ATGGCGGAAGGCGACCTCTCCTTCTTCGTGATGCTGGCCCGGCGCGAGAGCTTCTCGGCCACGGCGCAGGATCTGGGCCT
GTCGGCCTCGGCGGTGAGCCGGCGCCTCGCCCGGCTCGAGGATCGGCTGGGGGTCCGGCTGCTGAACCGCACGACGCGCA
AGGTGAGCCTCACGAGCGAGGGCGAGGCCTATTATGGCGCGGCCCTGCGGCTTCTCGACGAGATCGCGGATCTCGAACAC
AATCTCTCGCAGGGTCGCGACCGCCCGGCGGGCCTTCTGCGGATCAATGCCACGCTGGGTTTCGGGCGCACCCATCTCGC
CCCGGCCATCGCGCGCTTCCGCCGGATCCATCCGGCGGTGGAGGTGCAGCTTCTGTTGACCGATGCGCCGCTCAATCTCG
TCGAGGAGGGGATCGATCTCGGGATCCGCTTCGGAGCCCCGCCCTTCGGGCGCATGGTCATGCGGCTTCTGCAGCGCAAC
CGGAGGTTCCTCTGCGCGGCGCCCTCCTATCTCGAGGCCCGCGGGGTGCCGCAGAGCCTCACCGATCTGCAGCAGCACAG
CTGCATCGTGCTCAGGCAGGACCATGACGCCTACGACGTCTGGCGCTTCGACGATATCGGCGAGGCCTCGCCCTCGGCCA
AGGTGAGCGGCGAGCTCAGCACCAACGACGGCGAGATCGCGCTGGCCTGGGTGCTCGACGGGCAGGGGATCATGCTGCGC
TCGGAGTGGGACATCGCCCAGCATGTCCGTGAGGGTCGGCTGCGCCTCCTGCTGCCCCACTATCGCCAGACCGCCAACAT
CCACGCCATCTATCCGGAGCGCCACAATCTCTCGGCCAAGGTCCGCGTCTTTGCCGACCATCTGGCGGCGCATGTGCGCG
ACGCCGACGCCCGGATGCCGCTGCAGCTCGCGGCGGCCGAACTGCGGGCGGCCACCGCCCGTGCCTGA

Upstream 100 bases:

>100_bases
GGCTGATGCGCCGCTTGGCACGGCATGTTGAAAGTGTAGACTGTTCCTTGAAAGTTGATAGTCGGCGCTGCTTCAAAACT
TTATTGCGTCAGGAGCAAGA

Downstream 100 bases:

>100_bases
TCCCCACGGGCTCGCGGGGCAGACCCGGCGCCGCCCGGCCCGGAGGGGCCTCACCTGACCAGAAGCGAAAGGACGACCTC
ATGCGCATCCTCGATATCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MAEGDLSFFVMLARRESFSATAQDLGLSASAVSRRLARLEDRLGVRLLNRTTRKVSLTSEGEAYYGAALRLLDEIADLEH
NLSQGRDRPAGLLRINATLGFGRTHLAPAIARFRRIHPAVEVQLLLTDAPLNLVEEGIDLGIRFGAPPFGRMVMRLLQRN
RRFLCAAPSYLEARGVPQSLTDLQQHSCIVLRQDHDAYDVWRFDDIGEASPSAKVSGELSTNDGEIALAWVLDGQGIMLR
SEWDIAQHVREGRLRLLLPHYRQTANIHAIYPERHNLSAKVRVFADHLAAHVRDADARMPLQLAAAELRAATARA

Sequences:

>Translated_315_residues
MAEGDLSFFVMLARRESFSATAQDLGLSASAVSRRLARLEDRLGVRLLNRTTRKVSLTSEGEAYYGAALRLLDEIADLEH
NLSQGRDRPAGLLRINATLGFGRTHLAPAIARFRRIHPAVEVQLLLTDAPLNLVEEGIDLGIRFGAPPFGRMVMRLLQRN
RRFLCAAPSYLEARGVPQSLTDLQQHSCIVLRQDHDAYDVWRFDDIGEASPSAKVSGELSTNDGEIALAWVLDGQGIMLR
SEWDIAQHVREGRLRLLLPHYRQTANIHAIYPERHNLSAKVRVFADHLAAHVRDADARMPLQLAAAELRAATARA
>Mature_314_residues
AEGDLSFFVMLARRESFSATAQDLGLSASAVSRRLARLEDRLGVRLLNRTTRKVSLTSEGEAYYGAALRLLDEIADLEHN
LSQGRDRPAGLLRINATLGFGRTHLAPAIARFRRIHPAVEVQLLLTDAPLNLVEEGIDLGIRFGAPPFGRMVMRLLQRNR
RFLCAAPSYLEARGVPQSLTDLQQHSCIVLRQDHDAYDVWRFDDIGEASPSAKVSGELSTNDGEIALAWVLDGQGIMLRS
EWDIAQHVREGRLRLLLPHYRQTANIHAIYPERHNLSAKVRVFADHLAAHVRDADARMPLQLAAAELRAATARA

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=41.958041958042, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI87081978, Length=285, Percent_Identity=41.7543859649123, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1786401, Length=300, Percent_Identity=33.6666666666667, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=33.6769759450172, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789639, Length=291, Percent_Identity=30.9278350515464, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=31.7241379310345, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787589, Length=287, Percent_Identity=29.2682926829268, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788706, Length=179, Percent_Identity=31.2849162011173, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786448, Length=288, Percent_Identity=25.3472222222222, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790208, Length=125, Percent_Identity=36, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790011, Length=303, Percent_Identity=23.4323432343234, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788748, Length=153, Percent_Identity=36.6013071895425, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=117, Percent_Identity=29.9145299145299, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI157672245, Length=143, Percent_Identity=30.0699300699301, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789173, Length=192, Percent_Identity=25, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35061; Mature: 34929

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGDLSFFVMLARRESFSATAQDLGLSASAVSRRLARLEDRLGVRLLNRTTRKVSLTSE
CCCCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GEAYYGAALRLLDEIADLEHNLSQGRDRPAGLLRINATLGFGRTHLAPAIARFRRIHPAV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCE
EVQLLLTDAPLNLVEEGIDLGIRFGAPPFGRMVMRLLQRNRRFLCAAPSYLEARGVPQSL
EEEEEEECCCHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCEEEECCCHHHHCCCCHHH
TDLQQHSCIVLRQDHDAYDVWRFDDIGEASPSAKVSGELSTNDGEIALAWVLDGQGIMLR
HHHHHCCEEEEECCCCCCCEEECCCCCCCCCCCEECCEEECCCCCEEEEEEECCCEEEEE
SEWDIAQHVREGRLRLLLPHYRQTANIHAIYPERHNLSAKVRVFADHLAAHVRDADARMP
CCCCHHHHHHCCCEEEEECCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHCCCCCCCC
LQLAAAELRAATARA
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEGDLSFFVMLARRESFSATAQDLGLSASAVSRRLARLEDRLGVRLLNRTTRKVSLTSE
CCCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GEAYYGAALRLLDEIADLEHNLSQGRDRPAGLLRINATLGFGRTHLAPAIARFRRIHPAV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCE
EVQLLLTDAPLNLVEEGIDLGIRFGAPPFGRMVMRLLQRNRRFLCAAPSYLEARGVPQSL
EEEEEEECCCHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCEEEECCCHHHHCCCCHHH
TDLQQHSCIVLRQDHDAYDVWRFDDIGEASPSAKVSGELSTNDGEIALAWVLDGQGIMLR
HHHHHCCEEEEECCCCCCCEEECCCCCCCCCCCEECCEEECCCCCEEEEEEECCCEEEEE
SEWDIAQHVREGRLRLLLPHYRQTANIHAIYPERHNLSAKVRVFADHLAAHVRDADARMP
CCCCHHHHHHCCCEEEEECCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHCCCCCCCC
LQLAAAELRAATARA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]