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The map label for this gene is atpB [H]

Identifier: 77461953

GI number: 77461953

Start: 6428241

End: 6429110

Strand: Reverse

Name: atpB [H]

Synonym: Pfl01_5736

Alternate gene names: 77461953

Gene position: 6429110-6428241 (Counterclockwise)

Preceding gene: 77461954

Following gene: 77461952

Centisome position: 99.86

GC content: 58.39

Gene sequence:

>870_bases
ATGGCAGAAACAACCGCTTCGGGCTATATCCAGCACCACTTGCAGAACCTGACCTTCGGTCAGCTACCCAACGGCGGCTG
GGGCTTTGCCCACACCGCAGCAGAAGCCAAGGAAATGGGCTTCTGGGCTTTCCACGTCGATACTCTCGGCTGGTCGGTCG
CGCTGGGTCTGATCTTCGTTCTTCTTTTCCGCATGGCGGCCAAGAAGGCGACTTCCGGTCAGCCGGGTGCACTGCAGAAC
TTCGTTGAAGTCCTGGTCGAATTCGTCGATGGCAGCGTGAAAGACAGCTTCCATGGCCGTAGCCCGGTGATCGCACCGCT
GGCACTGACCATCTTCGTCTGGGTGTTTCTGATGAACGCCGTCGATCTGGTACCGGTCGACTGGGTTCCTCAGCTGGCCA
TCCTGATCTCCGGCGATCACCACATCCCGTTCCGCGCCGTGTCGACTACCGACCCGAACGCGACCCTGGGCATGGCGTTC
TCGGTTTTCGCACTGATCATTTTCTATAGCATCAAGGTCAAGGGCCTCGGCGGCTTCATCGGCGAGCTGACCCTGCACCC
GTTCGGCAGCAAGAACATCTTCGTTCAGGCTCTGCTGATCCCGGTGAACTTCCTGCTGGAATTCGTGACCCTGATCGCCA
AACCGATCTCTCTGGCTCTGCGTCTGTTCGGCAACATGTATGCCGGCGAGCTGGTGTTCATCCTGATCGCTGTGATGTTC
GGCAGCGGCCTGCTCTGGCTGAGCGGCCTGGGTGTTGTCCTGCAGTGGGCGTGGGCTGTGTTCCACATCCTGATCATCAC
CCTGCAGGCGTTCATCTTCATGATGCTGACCATCGTTTACCTGTCGATGGCGCACGAAGAAAACCATTAA

Upstream 100 bases:

>100_bases
GCTGTATTCGGCGCCTTCGTGCTGACTCAGTCGGTCAGCTGGTTCGCTCCCCTGCTGATGAGAACAAGACTTTCGAGACC
TTAGGGCGTTTGAGGCAACC

Downstream 100 bases:

>100_bases
GACCAGTCTCGACTAGTCTGATGTCCTTCCCGGTCAAACGGGAAGGGGCTCCTCACGGGGCACCATGAAACGATTTGTTT
TACCGCTTTAATCTAAAAAA

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MAETTASGYIQHHLQNLTFGQLPNGGWGFAHTAAEAKEMGFWAFHVDTLGWSVALGLIFVLLFRMAAKKATSGQPGALQN
FVEVLVEFVDGSVKDSFHGRSPVIAPLALTIFVWVFLMNAVDLVPVDWVPQLAILISGDHHIPFRAVSTTDPNATLGMAF
SVFALIIFYSIKVKGLGGFIGELTLHPFGSKNIFVQALLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMF
GSGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEENH

Sequences:

>Translated_289_residues
MAETTASGYIQHHLQNLTFGQLPNGGWGFAHTAAEAKEMGFWAFHVDTLGWSVALGLIFVLLFRMAAKKATSGQPGALQN
FVEVLVEFVDGSVKDSFHGRSPVIAPLALTIFVWVFLMNAVDLVPVDWVPQLAILISGDHHIPFRAVSTTDPNATLGMAF
SVFALIIFYSIKVKGLGGFIGELTLHPFGSKNIFVQALLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMF
GSGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEENH
>Mature_288_residues
AETTASGYIQHHLQNLTFGQLPNGGWGFAHTAAEAKEMGFWAFHVDTLGWSVALGLIFVLLFRMAAKKATSGQPGALQNF
VEVLVEFVDGSVKDSFHGRSPVIAPLALTIFVWVFLMNAVDLVPVDWVPQLAILISGDHHIPFRAVSTTDPNATLGMAFS
VFALIIFYSIKVKGLGGFIGELTLHPFGSKNIFVQALLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMFG
SGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEENH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=286, Percent_Identity=54.5454545454545, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 31705; Mature: 31574

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETTASGYIQHHLQNLTFGQLPNGGWGFAHTAAEAKEMGFWAFHVDTLGWSVALGLIFV
CCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHH
LLFRMAAKKATSGQPGALQNFVEVLVEFVDGSVKDSFHGRSPVIAPLALTIFVWVFLMNA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHH
VDLVPVDWVPQLAILISGDHHIPFRAVSTTDPNATLGMAFSVFALIIFYSIKVKGLGGFI
HHCCCCCCHHHEEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
GELTLHPFGSKNIFVQALLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMF
HHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEENH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AETTASGYIQHHLQNLTFGQLPNGGWGFAHTAAEAKEMGFWAFHVDTLGWSVALGLIFV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHH
LLFRMAAKKATSGQPGALQNFVEVLVEFVDGSVKDSFHGRSPVIAPLALTIFVWVFLMNA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHH
VDLVPVDWVPQLAILISGDHHIPFRAVSTTDPNATLGMAFSVFALIIFYSIKVKGLGGFI
HHCCCCCCHHHEEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
GELTLHPFGSKNIFVQALLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMF
HHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEENH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA