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The map label for this gene is atpA [H]

Identifier: 77461949

GI number: 77461949

Start: 6425206

End: 6426750

Strand: Reverse

Name: atpA [H]

Synonym: Pfl01_5732

Alternate gene names: 77461949

Gene position: 6426750-6425206 (Counterclockwise)

Preceding gene: 77461950

Following gene: 77461948

Centisome position: 99.82

GC content: 57.28

Gene sequence:

>1545_bases
ATGCAGCAACTCAATCCTTCCGAAATAAGTGAAATTATCAAGGGCCGCATCGAAAAGCTCGATGTGACCTCCCAAGCCCG
TAACGAAGGCACTGTCGTCAGCGTATCTGACGGTATCGTGCGGATTCACGGTCTGGCCGACGTCATGTACGGCGAGATGA
TCGAGTTTCCGGGCGGCGTCTACGGTATGGCCCTCAACCTGGAGCAAGACTCCGTAGGTGCCGTTGTACTGGGCGCATAC
ACGACTCTGGCTGAAGGCATGAGCGCCAAGTGCACCGGCCGCATCCTCGAAGTTCCGGTTGGTAAGGAACTGCTGGGTCG
CGTTGTCGACGCACTGGGTAACCCTGTTGACGGCAAAGGTCCACTGGGCAACACCGAGACCGACGCGGTCGAGAAAGTTG
CTCCGGGCGTGATCTGGCGTAAGTCGGTAGACCAGCCTGTACAGACTGGCTACAAGGCTGTCGATGCCATGATCCCTGTC
GGCCGTGGCCAGCGTGAGCTGATCATCGGTGACCGTCAGATCGGTAAAACCGCTCTGGCGATCGACGCGATCATCAACCA
GAAAGACAGCGGCATTTTCTGCGTCTACGTGGCAATCGGTCAGAAGCAATCGACCATCGCCAACGTGGTTCGCAAGCTGG
AAGAAAACGGTGCACTGGCTAACACCATCATCGTTGCAGCGAGCGCTTCGGAATCTGCAGCACTGCAATTCCTGGCTCCG
TACTCCGGTTGCACCATGGGTGAATTCTTCCGCGACCGCGGTGAAGACGCGCTGATCGTTTATGACGATCTGTCCAAGCA
AGCAGTGGCTTACCGCCAGATTTCCCTGCTGCTGCGCCGTCCACCAGGCCGTGAAGCTTACCCAGGCGACGTGTTCTATC
TCCACTCCCGTCTACTGGAGCGCGCATCCCGCGTTTCGGAAGAGTACGTAGAGAAGTTCACCAACGGCGCAGTGACCGGC
AAAACCGGTTCCCTGACCGCACTGCCGATCATCGAAACCCAGGCTGGCGACGTTTCCGCGTTCGTTCCGACCAACGTGAT
TTCCATCACCGACGGTCAGATCTTCCTGGAATCGGCCATGTTCAACTCGGGCATCCGCCCTGCAGTGAACGCCGGTGTTT
CGGTATCCCGTGTGGGTGGTGCCGCTCAGACCAAGATCATCAAGAAGCTGTCCGGTGGTATCCGTACCGCTCTGGCTCAG
TACCGTGAACTGGCGGCATTCGCCCAGTTCGCTTCTGACCTGGACGAAGCGACCCGCAAGCAACTTGAGCATGGTCAGCG
CGTTACCGAGCTGATGAAGCAGAAGCAATACGCGCCAATGTCGATCGCCGACATGTCGCTGTCGCTGTATGCCGCTGAGC
GTGGGTTCCTGACCGACATCGAAATCACCAAGATCGGCAGCTTCGAACAAGCGCTGATCGCTTTCTTCAACCGCGATCAC
GCCGATTTGATGGCCAAGATCAACGTTAAAGGTGACTTCAATGACGAAATCGACGCTGGCCTGAAGGCTGGTATCGAGAA
GTTCAAGGCCACCCAAACCTGGTAA

Upstream 100 bases:

>100_bases
CATCCGCGCCGGCGACCTGGTTATCGATGGCTCGATTCGCGGCAAAATCGCGAAACTTGCCGAAGCATTGAAATCTTGAG
TTTGAAGGGGCAGCAGAGCA

Downstream 100 bases:

>100_bases
GCCGCAGCGGGAGCCGCAAGGCTCCCGCTTGCTAACCTGATAGGTGTTACATGGCAGGCGCAAAAGAGATTCGCAGTAAG
ATTGCGAGCATCAAAAGCAC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQQLNPSEISEIIKGRIEKLDVTSQARNEGTVVSVSDGIVRIHGLADVMYGEMIEFPGGVYGMALNLEQDSVGAVVLGAY
TTLAEGMSAKCTGRILEVPVGKELLGRVVDALGNPVDGKGPLGNTETDAVEKVAPGVIWRKSVDQPVQTGYKAVDAMIPV
GRGQRELIIGDRQIGKTALAIDAIINQKDSGIFCVYVAIGQKQSTIANVVRKLEENGALANTIIVAASASESAALQFLAP
YSGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSEEYVEKFTNGAVTG
KTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAMFNSGIRPAVNAGVSVSRVGGAAQTKIIKKLSGGIRTALAQ
YRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPMSIADMSLSLYAAERGFLTDIEITKIGSFEQALIAFFNRDH
ADLMAKINVKGDFNDEIDAGLKAGIEKFKATQTW

Sequences:

>Translated_514_residues
MQQLNPSEISEIIKGRIEKLDVTSQARNEGTVVSVSDGIVRIHGLADVMYGEMIEFPGGVYGMALNLEQDSVGAVVLGAY
TTLAEGMSAKCTGRILEVPVGKELLGRVVDALGNPVDGKGPLGNTETDAVEKVAPGVIWRKSVDQPVQTGYKAVDAMIPV
GRGQRELIIGDRQIGKTALAIDAIINQKDSGIFCVYVAIGQKQSTIANVVRKLEENGALANTIIVAASASESAALQFLAP
YSGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSEEYVEKFTNGAVTG
KTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAMFNSGIRPAVNAGVSVSRVGGAAQTKIIKKLSGGIRTALAQ
YRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPMSIADMSLSLYAAERGFLTDIEITKIGSFEQALIAFFNRDH
ADLMAKINVKGDFNDEIDAGLKAGIEKFKATQTW
>Mature_514_residues
MQQLNPSEISEIIKGRIEKLDVTSQARNEGTVVSVSDGIVRIHGLADVMYGEMIEFPGGVYGMALNLEQDSVGAVVLGAY
TTLAEGMSAKCTGRILEVPVGKELLGRVVDALGNPVDGKGPLGNTETDAVEKVAPGVIWRKSVDQPVQTGYKAVDAMIPV
GRGQRELIIGDRQIGKTALAIDAIINQKDSGIFCVYVAIGQKQSTIANVVRKLEENGALANTIIVAASASESAALQFLAP
YSGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSEEYVEKFTNGAVTG
KTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAMFNSGIRPAVNAGVSVSRVGGAAQTKIIKKLSGGIRTALAQ
YRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPMSIADMSLSLYAAERGFLTDIEITKIGSFEQALIAFFNRDH
ADLMAKINVKGDFNDEIDAGLKAGIEKFKATQTW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=518, Percent_Identity=56.3706563706564, Blast_Score=580, Evalue=1e-166,
Organism=Homo sapiens, GI4757810, Length=518, Percent_Identity=56.3706563706564, Blast_Score=580, Evalue=1e-166,
Organism=Homo sapiens, GI19913426, Length=374, Percent_Identity=26.7379679144385, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19913428, Length=374, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI32189394, Length=437, Percent_Identity=24.0274599542334, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI19913424, Length=333, Percent_Identity=25.2252252252252, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1790172, Length=512, Percent_Identity=77.9296875, Blast_Score=835, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=389, Percent_Identity=26.2210796915167, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788251, Length=390, Percent_Identity=26.1538461538462, Blast_Score=115, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71988063, Length=513, Percent_Identity=55.9454191033138, Blast_Score=570, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI71988080, Length=513, Percent_Identity=55.9454191033138, Blast_Score=568, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71988074, Length=513, Percent_Identity=52.2417153996101, Blast_Score=522, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=25.8152173913043, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=369, Percent_Identity=26.0162601626016, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=321, Percent_Identity=24.9221183800623, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=63.8297872340426, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=253, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=514, Percent_Identity=54.4747081712062, Blast_Score=573, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6322581, Length=433, Percent_Identity=24.4803695150115, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6319603, Length=383, Percent_Identity=25.8485639686684, Blast_Score=113, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24658560, Length=513, Percent_Identity=56.140350877193, Blast_Score=565, Evalue=1e-161,
Organism=Drosophila melanogaster, GI281361666, Length=314, Percent_Identity=28.343949044586, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646341, Length=314, Percent_Identity=28.343949044586, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136796, Length=314, Percent_Identity=28.343949044586, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24638766, Length=330, Percent_Identity=26.0606060606061, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574560, Length=323, Percent_Identity=25.077399380805, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583992, Length=319, Percent_Identity=24.7648902821317, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583988, Length=248, Percent_Identity=26.6129032258064, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583986, Length=248, Percent_Identity=26.6129032258064, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583984, Length=248, Percent_Identity=26.6129032258064, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129479, Length=318, Percent_Identity=25.7861635220126, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55323; Mature: 55323

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLNPSEISEIIKGRIEKLDVTSQARNEGTVVSVSDGIVRIHGLADVMYGEMIEFPGGV
CCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCEEEECCCEEEEEHHHHHHHHHHHHCCCCE
YGMALNLEQDSVGAVVLGAYTTLAEGMSAKCTGRILEVPVGKELLGRVVDALGNPVDGKG
EEEEEEECCCCCCEEEEHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCC
PLGNTETDAVEKVAPGVIWRKSVDQPVQTGYKAVDAMIPVGRGQRELIIGDRQIGKTALA
CCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCHHHHH
IDAIINQKDSGIFCVYVAIGQKQSTIANVVRKLEENGALANTIIVAASASESAALQFLAP
HHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHEEEECC
YSGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLE
CCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RASRVSEEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAM
HHHHHHHHHHHHHHCCCEECCCCCEEEEEEEECCCCCEEEECCCCEEEECCCHHHHHHHH
FNSGIRPAVNAGVSVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDEATRK
HCCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLEHGQRVTELMKQKQYAPMSIADMSLSLYAAERGFLTDIEITKIGSFEQALIAFFNRDH
HHHHHHHHHHHHHHHCCCCCEEHHHHEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCC
ADLMAKINVKGDFNDEIDAGLKAGIEKFKATQTW
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQQLNPSEISEIIKGRIEKLDVTSQARNEGTVVSVSDGIVRIHGLADVMYGEMIEFPGGV
CCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCEEEECCCEEEEEHHHHHHHHHHHHCCCCE
YGMALNLEQDSVGAVVLGAYTTLAEGMSAKCTGRILEVPVGKELLGRVVDALGNPVDGKG
EEEEEEECCCCCCEEEEHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCC
PLGNTETDAVEKVAPGVIWRKSVDQPVQTGYKAVDAMIPVGRGQRELIIGDRQIGKTALA
CCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCHHHHH
IDAIINQKDSGIFCVYVAIGQKQSTIANVVRKLEENGALANTIIVAASASESAALQFLAP
HHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHEEEECC
YSGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLE
CCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RASRVSEEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAM
HHHHHHHHHHHHHHCCCEECCCCCEEEEEEEECCCCCEEEECCCCEEEECCCHHHHHHHH
FNSGIRPAVNAGVSVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDEATRK
HCCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLEHGQRVTELMKQKQYAPMSIADMSLSLYAAERGFLTDIEITKIGSFEQALIAFFNRDH
HHHHHHHHHHHHHHHCCCCCEEHHHHEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCC
ADLMAKINVKGDFNDEIDAGLKAGIEKFKATQTW
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA