Click here to switch to the map view.

The map label for this gene is prpC [H]

Identifier: 77461797

GI number: 77461797

Start: 6245617

End: 6246345

Strand: Reverse

Name: prpC [H]

Synonym: Pfl01_5576

Alternate gene names: 77461797

Gene position: 6246345-6245617 (Counterclockwise)

Preceding gene: 77461798

Following gene: 77461796

Centisome position: 97.02

GC content: 66.53

Gene sequence:

>729_bases
ATGCTGGTGGCCAGTCCCTGGCGCAGCGCGGCGCGAACCGACCCGGGCAAGGTGCGGTCGCGCAACGAAGATGCCTTCCT
CGACACCCCGCAGCATGGGCTGTGGGTGGTCGCGGACGGCATGGGCGGTCATCAGGGTGGCGACATCGCCAGCCAGTTGA
TCGTCGCCAGCCTGGCTGAACTGCCGCAGCACGAAGATTTCGACGAACGCCTCAAAGCCATCCGCCAGTGCCTGCACTGG
CTGAACCGGCGCCTGGGGCAGGAGTTGACCGTCACCGCCGGGCGCCACGACAGCATCATGGGCAGCACCGTCGTGGCGCT
GCTGGTGGACGGCAATCGCGCGGCCTGCATCTGGGCCGGCGACAGCCGTTGCTACATGTGGCGCGGGCAGCGGTTATATC
AGCTGTCGAAGGATCACTCGCTGCAGCAACAACTGATCGACGAACAGCAGATGAGCGTCGAACAGGCAGCGGCGCACCCG
GCGGCCCAGGCCCTGACCCGGGCGGTCGGCGCGGCGGAACAGTTGACCCTGGATGTGCTGGAACTCGAGGTCTATCCCGG
TGATGTGTTCTTGCTGTGCAGCGATGGTTTGTATCAAGGCCTGAGCAGCGATGCCCTCGGCAATGCTCTCAGCCTGGCGG
CGCCACACGTGGCGCTGGAACGTCTGTTCGACGGCGCCCTGCGGGGTGCCGCTCGCGACAACCTGACGGCCGTGGTGATC
CGCCAATGA

Upstream 100 bases:

>100_bases
TGGGTGGCCTGCGCGCCAACTACCTGCTGACCAGCCAGCGCACGCCGAACCCGTTCGACATGGGCGTAATGCGTACCTTC
CGTATGCCGGTGCAGCTCTG

Downstream 100 bases:

>100_bases
CTGAAATCGAATCCTCAGTCGACGACTTGCTGATGAGCGAAGAGCAGGCCAACAACCTGACTTATTTCGCCTTCGCCAAG
CAACATAATGCCGAACCCGC

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MLVASPWRSAARTDPGKVRSRNEDAFLDTPQHGLWVVADGMGGHQGGDIASQLIVASLAELPQHEDFDERLKAIRQCLHW
LNRRLGQELTVTAGRHDSIMGSTVVALLVDGNRAACIWAGDSRCYMWRGQRLYQLSKDHSLQQQLIDEQQMSVEQAAAHP
AAQALTRAVGAAEQLTLDVLELEVYPGDVFLLCSDGLYQGLSSDALGNALSLAAPHVALERLFDGALRGAARDNLTAVVI
RQ

Sequences:

>Translated_242_residues
MLVASPWRSAARTDPGKVRSRNEDAFLDTPQHGLWVVADGMGGHQGGDIASQLIVASLAELPQHEDFDERLKAIRQCLHW
LNRRLGQELTVTAGRHDSIMGSTVVALLVDGNRAACIWAGDSRCYMWRGQRLYQLSKDHSLQQQLIDEQQMSVEQAAAHP
AAQALTRAVGAAEQLTLDVLELEVYPGDVFLLCSDGLYQGLSSDALGNALSLAAPHVALERLFDGALRGAARDNLTAVVI
RQ
>Mature_242_residues
MLVASPWRSAARTDPGKVRSRNEDAFLDTPQHGLWVVADGMGGHQGGDIASQLIVASLAELPQHEDFDERLKAIRQCLHW
LNRRLGQELTVTAGRHDSIMGSTVVALLVDGNRAACIWAGDSRCYMWRGQRLYQLSKDHSLQQQLIDEQQMSVEQAAAHP
AAQALTRAVGAAEQLTLDVLELEVYPGDVFLLCSDGLYQGLSSDALGNALSLAAPHVALERLFDGALRGAARDNLTAVVI
RQ

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 26343; Mature: 26343

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVASPWRSAARTDPGKVRSRNEDAFLDTPQHGLWVVADGMGGHQGGDIASQLIVASLAE
CCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
LPQHEDFDERLKAIRQCLHWLNRRLGQELTVTAGRHDSIMGSTVVALLVDGNRAACIWAG
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCEEEEEEECCCCEEEEEEC
DSRCYMWRGQRLYQLSKDHSLQQQLIDEQQMSVEQAAAHPAAQALTRAVGAAEQLTLDVL
CCEEEEECCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHEEEEE
ELEVYPGDVFLLCSDGLYQGLSSDALGNALSLAAPHVALERLFDGALRGAARDNLTAVVI
EEEEECCCEEEEECCHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RQ
EC
>Mature Secondary Structure
MLVASPWRSAARTDPGKVRSRNEDAFLDTPQHGLWVVADGMGGHQGGDIASQLIVASLAE
CCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
LPQHEDFDERLKAIRQCLHWLNRRLGQELTVTAGRHDSIMGSTVVALLVDGNRAACIWAG
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCEEEEEEECCCCEEEEEEC
DSRCYMWRGQRLYQLSKDHSLQQQLIDEQQMSVEQAAAHPAAQALTRAVGAAEQLTLDVL
CCEEEEECCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHEEEEE
ELEVYPGDVFLLCSDGLYQGLSSDALGNALSLAAPHVALERLFDGALRGAARDNLTAVVI
EEEEECCCEEEEECCHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RQ
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]