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The map label for this gene is yheS [H]

Identifier: 77461699

GI number: 77461699

Start: 6145594

End: 6147504

Strand: Reverse

Name: yheS [H]

Synonym: Pfl01_5478

Alternate gene names: 77461699

Gene position: 6147504-6145594 (Counterclockwise)

Preceding gene: 77461701

Following gene: 77461698

Centisome position: 95.48

GC content: 63.68

Gene sequence:

>1911_bases
ATGATCCGACTTCAGAACCTGACTTTACAGCGTGGCCCGCAACGTCTGCTAGAAGACGCCGAGCTGACCCTGCACGCCGG
CCACAAAGCCGGCCTCATCGGTGCCAACGGCGCCGGCAAATCCAGCCTGTTCGCCTTGCTCCGCGGTGAGTTGCACCCGG
ACTCGGGCGACTGCCTGCTGCCGGCCGACTGGCGTATCGCCCACATGCGCCAGGAGGTCGACACACTCGAGCGTCTGGCG
GTCGACTATGTGCTCGACGGCGACCTGCGCCTGCGCGAAGTGCAGCGTGAGCTCGCGGCAGCCGAAGAGGCCCACGACGG
CACCGCGCTGGCCCGTCTGCACGCCGAACTCGACAGCGCCGACGGCTACACCGCCGATGCGCGTGCACGCAAGTTGCTCG
CCGGCCTCGGATTCACCAACGAGCAGATGGATCGTCAGGTAGGAGATTTCTCCGGTGGCTGGCGGATGCGTCTGAACCTT
GCGCAGGCTTTGATGTGCCCATCAGACCTGTTGCTGCTCGACGAACCGACCAACCACCTGGATCTCGACGCCATCATCTG
GCTCGAAGAGTGGCTGAAAAGTTACCCCGGCACCTTGCTGCTGATTTCTCACGACCGGGACTTCCTCGATGAAGTGGTCG
ATCACGTGGCCCACGTCGATCAGCGCAAGCTGACGCTCTACCGTGGCGGCTACACCGCGTTCGAACGCGCCCGTGCCGAG
CGTCTGGCCCAGCAGCAACAGGCCTACGAGAAGCAACAGGCGCAGCGTGCGCACATGGAAAGCTACATCGCCCGGTTCAA
GGCCCAGGCGACCAAGGCCCGTCAGGCCCAGAGCCGGATCAAGGCGCTGGAGCGCATGGAAGAGCTGTCGGCTGCCCACG
TCGACTCGCCGTTCGATTTCGTGTTCCGCGAGTCGACCAAGATCTCCAGCCCGCTGATCGATCTGTCCGATGCACGTCTG
GGTTATGGCGAGAAAACCGTGCTGGAGAAGGTCAAGCTGCAACTGACCCCCGGCGCGCGGATCGGCTTGCTCGGCCCCAA
CGGCGCGGGTAAATCGACCCTGATCAAGAACCTTGCCGGCGAGCTGTCACCGCTGGCCGGGCGCCTGACTCGCGGTGAGA
ACACCGTGGTCGGTTACTTCGCTCAGCATCAACTCGACTCGCTGGATTCCAAGGCCAGCCCGTTGCTGCACTTGCAGCGT
CTGGCGCCGACCGAGCGCGAGCAGACCCTGCGCGATTTCCTTGGTGGTTTCGACTTCCGTGGCGCACGGATCGACGAACC
GGTGCTGAATTTCTCCGGTGGCGAAAAGGCCCGTCTGGCCCTGGCGCTGATCGCCTGGGAACGGCCGAACCTGCTGCTGC
TCGACGAACCGACCAACCACCTCGACCTGGAAATGCGCCTGGCGCTGACCATGGCGTTGCAGGAATTCAGCGGCGCGGTG
TTGGTGGTTTCCCACGATCGGCATCTGCTCAAGAGCACCACCGACAACTTCTTCCTGGTCGCGGACAGCAAGGTCGAGGA
GTTCGATGGCGACCTTGAGGACTACGCCCGTTGGCTGGTCGAGTACCGTCAGCGCAACGCCCCGGTCAGCAACACACCGG
TCAACCCGGACAAGACCGACAAGAAGGCCCAGCGTCAAGCCGCCGCTGCGTTGCGTCAGCAACTGGCGCCGCACAAGCGC
GAAGCCGACAAGCTCGAAGCCGAGCTCGGCAAGCTGCACGAGAAGTTGGCGAAGGTCGATGCCAGCCTTGGCGACAGCGA
CCTCTACGAGCCGGCGCGCAAGAACGAATTGCGTGACTTGCTGGCCGAACAGGCCAAGCTGAAAGTCCGCGAAGGCGAAC
TTGAAGAAGCGTGGATGCAAGCCCTGGAAACCCTGGAAAGCATGCAGGCGGAGCTGGAGGCGTTGTCCTGA

Upstream 100 bases:

>100_bases
CCGGGACGGGCGTAGACGGCAAGGGCAAAGCTCCACAGGTCAGAGGACATCGTGCTACTCGCGCCAGTTGCGGGGGAAGC
TGGTAGACTCCGCCGCCATT

Downstream 100 bases:

>100_bases
TGGAAGCCTTCAAACTTCCATTGCCGGCGATGTGGGTCGAGCCGATCTGGCTCGGCGTGCAGATTCTGCTGATCCTGTTG
GCCGGCTACTTCGCCCAGCG

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MIRLQNLTLQRGPQRLLEDAELTLHAGHKAGLIGANGAGKSSLFALLRGELHPDSGDCLLPADWRIAHMRQEVDTLERLA
VDYVLDGDLRLREVQRELAAAEEAHDGTALARLHAELDSADGYTADARARKLLAGLGFTNEQMDRQVGDFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAIIWLEEWLKSYPGTLLLISHDRDFLDEVVDHVAHVDQRKLTLYRGGYTAFERARAE
RLAQQQQAYEKQQAQRAHMESYIARFKAQATKARQAQSRIKALERMEELSAAHVDSPFDFVFRESTKISSPLIDLSDARL
GYGEKTVLEKVKLQLTPGARIGLLGPNGAGKSTLIKNLAGELSPLAGRLTRGENTVVGYFAQHQLDSLDSKASPLLHLQR
LAPTEREQTLRDFLGGFDFRGARIDEPVLNFSGGEKARLALALIAWERPNLLLLDEPTNHLDLEMRLALTMALQEFSGAV
LVVSHDRHLLKSTTDNFFLVADSKVEEFDGDLEDYARWLVEYRQRNAPVSNTPVNPDKTDKKAQRQAAAALRQQLAPHKR
EADKLEAELGKLHEKLAKVDASLGDSDLYEPARKNELRDLLAEQAKLKVREGELEEAWMQALETLESMQAELEALS

Sequences:

>Translated_636_residues
MIRLQNLTLQRGPQRLLEDAELTLHAGHKAGLIGANGAGKSSLFALLRGELHPDSGDCLLPADWRIAHMRQEVDTLERLA
VDYVLDGDLRLREVQRELAAAEEAHDGTALARLHAELDSADGYTADARARKLLAGLGFTNEQMDRQVGDFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAIIWLEEWLKSYPGTLLLISHDRDFLDEVVDHVAHVDQRKLTLYRGGYTAFERARAE
RLAQQQQAYEKQQAQRAHMESYIARFKAQATKARQAQSRIKALERMEELSAAHVDSPFDFVFRESTKISSPLIDLSDARL
GYGEKTVLEKVKLQLTPGARIGLLGPNGAGKSTLIKNLAGELSPLAGRLTRGENTVVGYFAQHQLDSLDSKASPLLHLQR
LAPTEREQTLRDFLGGFDFRGARIDEPVLNFSGGEKARLALALIAWERPNLLLLDEPTNHLDLEMRLALTMALQEFSGAV
LVVSHDRHLLKSTTDNFFLVADSKVEEFDGDLEDYARWLVEYRQRNAPVSNTPVNPDKTDKKAQRQAAAALRQQLAPHKR
EADKLEAELGKLHEKLAKVDASLGDSDLYEPARKNELRDLLAEQAKLKVREGELEEAWMQALETLESMQAELEALS
>Mature_636_residues
MIRLQNLTLQRGPQRLLEDAELTLHAGHKAGLIGANGAGKSSLFALLRGELHPDSGDCLLPADWRIAHMRQEVDTLERLA
VDYVLDGDLRLREVQRELAAAEEAHDGTALARLHAELDSADGYTADARARKLLAGLGFTNEQMDRQVGDFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAIIWLEEWLKSYPGTLLLISHDRDFLDEVVDHVAHVDQRKLTLYRGGYTAFERARAE
RLAQQQQAYEKQQAQRAHMESYIARFKAQATKARQAQSRIKALERMEELSAAHVDSPFDFVFRESTKISSPLIDLSDARL
GYGEKTVLEKVKLQLTPGARIGLLGPNGAGKSTLIKNLAGELSPLAGRLTRGENTVVGYFAQHQLDSLDSKASPLLHLQR
LAPTEREQTLRDFLGGFDFRGARIDEPVLNFSGGEKARLALALIAWERPNLLLLDEPTNHLDLEMRLALTMALQEFSGAV
LVVSHDRHLLKSTTDNFFLVADSKVEEFDGDLEDYARWLVEYRQRNAPVSNTPVNPDKTDKKAQRQAAAALRQQLAPHKR
EADKLEAELGKLHEKLAKVDASLGDSDLYEPARKNELRDLLAEQAKLKVREGELEEAWMQALETLESMQAELEALS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=534, Percent_Identity=36.8913857677903, Blast_Score=341, Evalue=2e-93,
Organism=Homo sapiens, GI27881506, Length=527, Percent_Identity=36.8121442125237, Blast_Score=322, Evalue=6e-88,
Organism=Homo sapiens, GI10947137, Length=527, Percent_Identity=36.8121442125237, Blast_Score=322, Evalue=7e-88,
Organism=Homo sapiens, GI10947135, Length=543, Percent_Identity=35.1749539594843, Blast_Score=272, Evalue=8e-73,
Organism=Homo sapiens, GI69354671, Length=543, Percent_Identity=35.1749539594843, Blast_Score=272, Evalue=9e-73,
Organism=Escherichia coli, GI1789751, Length=630, Percent_Identity=54.9206349206349, Blast_Score=698, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=530, Percent_Identity=36.7924528301887, Blast_Score=330, Evalue=2e-91,
Organism=Escherichia coli, GI2367384, Length=536, Percent_Identity=31.9029850746269, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1787182, Length=634, Percent_Identity=29.1798107255521, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI87081782, Length=525, Percent_Identity=26.8571428571429, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788165, Length=198, Percent_Identity=35.3535353535354, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786975, Length=511, Percent_Identity=27.3972602739726, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1787758, Length=196, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994997, Length=229, Percent_Identity=27.9475982532751, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789891, Length=211, Percent_Identity=26.5402843601896, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=223, Percent_Identity=25.5605381165919, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787029, Length=243, Percent_Identity=23.8683127572016, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081791, Length=292, Percent_Identity=24.6575342465753, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786698, Length=195, Percent_Identity=28.7179487179487, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=537, Percent_Identity=37.4301675977654, Blast_Score=338, Evalue=6e-93,
Organism=Caenorhabditis elegans, GI17559834, Length=554, Percent_Identity=32.8519855595668, Blast_Score=316, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17555318, Length=523, Percent_Identity=34.6080305927342, Blast_Score=315, Evalue=4e-86,
Organism=Saccharomyces cerevisiae, GI6321121, Length=537, Percent_Identity=37.243947858473, Blast_Score=349, Evalue=6e-97,
Organism=Saccharomyces cerevisiae, GI6320874, Length=529, Percent_Identity=34.7826086956522, Blast_Score=304, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6325030, Length=388, Percent_Identity=31.9587628865979, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6324314, Length=407, Percent_Identity=27.5184275184275, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323278, Length=393, Percent_Identity=28.7531806615776, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=37.3814041745731, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24642252, Length=527, Percent_Identity=37.7609108159393, Blast_Score=352, Evalue=5e-97,
Organism=Drosophila melanogaster, GI18859989, Length=527, Percent_Identity=37.7609108159393, Blast_Score=352, Evalue=5e-97,
Organism=Drosophila melanogaster, GI24641342, Length=538, Percent_Identity=35.3159851301115, Blast_Score=320, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71144; Mature: 71144

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLQNLTLQRGPQRLLEDAELTLHAGHKAGLIGANGAGKSSLFALLRGELHPDSGDCLL
CEEECCCHHHCCHHHHHCCCCEEEECCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCEEE
PADWRIAHMRQEVDTLERLAVDYVLDGDLRLREVQRELAAAEEAHDGTALARLHAELDSA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DGYTADARARKLLAGLGFTNEQMDRQVGDFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCEEEEECCCCCC
DLDAIIWLEEWLKSYPGTLLLISHDRDFLDEVVDHVAHVDQRKLTLYRGGYTAFERARAE
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHH
RLAQQQQAYEKQQAQRAHMESYIARFKAQATKARQAQSRIKALERMEELSAAHVDSPFDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VFRESTKISSPLIDLSDARLGYGEKTVLEKVKLQLTPGARIGLLGPNGAGKSTLIKNLAG
HHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHEEECCCCEEEEECCCCCCHHHHHHHHHH
ELSPLAGRLTRGENTVVGYFAQHQLDSLDSKASPLLHLQRLAPTEREQTLRDFLGGFDFR
HHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCC
GARIDEPVLNFSGGEKARLALALIAWERPNLLLLDEPTNHLDLEMRLALTMALQEFSGAV
CCCCCCCCCCCCCCCHHHEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEE
LVVSHDRHLLKSTTDNFFLVADSKVEEFDGDLEDYARWLVEYRQRNAPVSNTPVNPDKTD
EEEECCCHHHHCCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
KKAQRQAAAALRQQLAPHKREADKLEAELGKLHEKLAKVDASLGDSDLYEPARKNELRDL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHH
LAEQAKLKVREGELEEAWMQALETLESMQAELEALS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRLQNLTLQRGPQRLLEDAELTLHAGHKAGLIGANGAGKSSLFALLRGELHPDSGDCLL
CEEECCCHHHCCHHHHHCCCCEEEECCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCEEE
PADWRIAHMRQEVDTLERLAVDYVLDGDLRLREVQRELAAAEEAHDGTALARLHAELDSA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DGYTADARARKLLAGLGFTNEQMDRQVGDFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCEEEEECCCCCC
DLDAIIWLEEWLKSYPGTLLLISHDRDFLDEVVDHVAHVDQRKLTLYRGGYTAFERARAE
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHH
RLAQQQQAYEKQQAQRAHMESYIARFKAQATKARQAQSRIKALERMEELSAAHVDSPFDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VFRESTKISSPLIDLSDARLGYGEKTVLEKVKLQLTPGARIGLLGPNGAGKSTLIKNLAG
HHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHEEECCCCEEEEECCCCCCHHHHHHHHHH
ELSPLAGRLTRGENTVVGYFAQHQLDSLDSKASPLLHLQRLAPTEREQTLRDFLGGFDFR
HHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCC
GARIDEPVLNFSGGEKARLALALIAWERPNLLLLDEPTNHLDLEMRLALTMALQEFSGAV
CCCCCCCCCCCCCCCHHHEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEE
LVVSHDRHLLKSTTDNFFLVADSKVEEFDGDLEDYARWLVEYRQRNAPVSNTPVNPDKTD
EEEECCCHHHHCCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
KKAQRQAAAALRQQLAPHKREADKLEAELGKLHEKLAKVDASLGDSDLYEPARKNELRDL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHH
LAEQAKLKVREGELEEAWMQALETLESMQAELEALS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]