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The map label for this gene is lrhA [H]

Identifier: 77460025

GI number: 77460025

Start: 4305669

End: 4306526

Strand: Direct

Name: lrhA [H]

Synonym: Pfl01_3803

Alternate gene names: 77460025

Gene position: 4305669-4306526 (Clockwise)

Preceding gene: 77460021

Following gene: 77460030

Centisome position: 66.87

GC content: 65.97

Gene sequence:

>858_bases
ATGCTGGATCTGGAACTGCTGAAAACCTTCGTCTGCGTGGTCGATGAAGGCAGCTTCACCCGCGCCGCCGAACGCGTCCA
CCGCACCCAGTCAACGGTCAGCCAACAGGTGCGCAAACTCGAAGACCTGGTCGGCCACGCGCTGCTGTTGCGCGACCGCA
CCGGGCTGAACGTCAGCGTCACCGAGCACGGCGAACTGCTGATTCATTACGCCCGCCGCCTGCTGGCCTTGTCGGCCGAG
GCCAGCGAAGCCCTGGCCAGCGATCTGGATCTGGAAATCCTGCGCATCGGCATGCCGGAAGACTTCGACGCCCGACGCAT
GGCGCTGATCCTCGCCGGCTTCACCCGCAGCCACCCGCAAGCACGGCTGGAAACCGTCAGCGGCATGAGCCTCGACCTGC
GCCAACGCCTCGACAGCGGCGAAATCGACATCGCCCTGATCAAACGCGAACCCGACAGCGGCCCGGCCTGGGCGACCTGG
CCGGAGCGACTCGTTTGGGTCAAAGGCACGGAATTCGACTCATCCATTGGCGTGTTGCCGCTGGCATTGTTTCCCCAAGG
CTGCCTTTACAGGCAACGGGCGATCCGCCTGCTTGACGTGGCGCAACGCCCCTGGCGGGTGGCCTTCGGCAGCCACAGTC
TGACCGGCATTCAAGCGGCGGTGGCCTCAGGGCTTGGGGTTTCGGTGCTGCCGGCGTCGGCGGTGTTGCCGGAGCATCGG
GTGTGCACGGACTTGCCGCCGCTGCCGCCGACGGAGCTGGCGCTGGTCAGCCGCGAGGGGGTGTTGAGCGGATTGCAGCG
GGGGTTGGTGGAGTTTTTGCGCGGGGAATTGGGGGTGGATGCAGGGGGATTTGCTTGA

Upstream 100 bases:

>100_bases
CTCTGCAAGTGAGGGCTTCAGCTTATGAACTCGGGGTGATAGTGTGAAATTAAATAAATAGCCGACCGTCAGTTGCCAAA
CAAATATCGAGAGCGCCGCC

Downstream 100 bases:

>100_bases
TCCCCCCAAATGGCGCTGAGCTCAGGGCTTGTTGACTTCGCGCAGCAGGTCTGCGACCGGGAGGTTCATGGTGTTTGAGT
AGTAGGGTTTGTAGCCGTAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLDLELLKTFVCVVDEGSFTRAAERVHRTQSTVSQQVRKLEDLVGHALLLRDRTGLNVSVTEHGELLIHYARRLLALSAE
ASEALASDLDLEILRIGMPEDFDARRMALILAGFTRSHPQARLETVSGMSLDLRQRLDSGEIDIALIKREPDSGPAWATW
PERLVWVKGTEFDSSIGVLPLALFPQGCLYRQRAIRLLDVAQRPWRVAFGSHSLTGIQAAVASGLGVSVLPASAVLPEHR
VCTDLPPLPPTELALVSREGVLSGLQRGLVEFLRGELGVDAGGFA

Sequences:

>Translated_285_residues
MLDLELLKTFVCVVDEGSFTRAAERVHRTQSTVSQQVRKLEDLVGHALLLRDRTGLNVSVTEHGELLIHYARRLLALSAE
ASEALASDLDLEILRIGMPEDFDARRMALILAGFTRSHPQARLETVSGMSLDLRQRLDSGEIDIALIKREPDSGPAWATW
PERLVWVKGTEFDSSIGVLPLALFPQGCLYRQRAIRLLDVAQRPWRVAFGSHSLTGIQAAVASGLGVSVLPASAVLPEHR
VCTDLPPLPPTELALVSREGVLSGLQRGLVEFLRGELGVDAGGFA
>Mature_285_residues
MLDLELLKTFVCVVDEGSFTRAAERVHRTQSTVSQQVRKLEDLVGHALLLRDRTGLNVSVTEHGELLIHYARRLLALSAE
ASEALASDLDLEILRIGMPEDFDARRMALILAGFTRSHPQARLETVSGMSLDLRQRLDSGEIDIALIKREPDSGPAWATW
PERLVWVKGTEFDSSIGVLPLALFPQGCLYRQRAIRLLDVAQRPWRVAFGSHSLTGIQAAVASGLGVSVLPASAVLPEHR
VCTDLPPLPPTELALVSREGVLSGLQRGLVEFLRGELGVDAGGFA

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=258, Percent_Identity=34.1085271317829, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787806, Length=257, Percent_Identity=26.8482490272374, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788887, Length=156, Percent_Identity=32.0512820512821, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI157672245, Length=154, Percent_Identity=31.1688311688312, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=28.9156626506024, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790262, Length=146, Percent_Identity=28.7671232876712, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31122; Mature: 31122

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLELLKTFVCVVDEGSFTRAAERVHRTQSTVSQQVRKLEDLVGHALLLRDRTGLNVSV
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEE
TEHGELLIHYARRLLALSAEASEALASDLDLEILRIGMPEDFDARRMALILAGFTRSHPQ
CCCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCH
ARLETVSGMSLDLRQRLDSGEIDIALIKREPDSGPAWATWPERLVWVKGTEFDSSIGVLP
HHHHHHCCCCHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCH
LALFPQGCLYRQRAIRLLDVAQRPWRVAFGSHSLTGIQAAVASGLGVSVLPASAVLPEHR
HHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCEECCHHHCCCCCC
VCTDLPPLPPTELALVSREGVLSGLQRGLVEFLRGELGVDAGGFA
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLDLELLKTFVCVVDEGSFTRAAERVHRTQSTVSQQVRKLEDLVGHALLLRDRTGLNVSV
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEE
TEHGELLIHYARRLLALSAEASEALASDLDLEILRIGMPEDFDARRMALILAGFTRSHPQ
CCCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCH
ARLETVSGMSLDLRQRLDSGEIDIALIKREPDSGPAWATWPERLVWVKGTEFDSSIGVLP
HHHHHHCCCCHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCH
LALFPQGCLYRQRAIRLLDVAQRPWRVAFGSHSLTGIQAAVASGLGVSVLPASAVLPEHR
HHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCEECCHHHCCCCCC
VCTDLPPLPPTELALVSREGVLSGLQRGLVEFLRGELGVDAGGFA
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]