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The map label for this gene is exbB [H]

Identifier: 77459960

GI number: 77459960

Start: 4224321

End: 4225025

Strand: Direct

Name: exbB [H]

Synonym: Pfl01_3738

Alternate gene names: 77459960

Gene position: 4224321-4225025 (Clockwise)

Preceding gene: 77459959

Following gene: 77459961

Centisome position: 65.61

GC content: 64.4

Gene sequence:

>705_bases
ATGAACGATTCTCTGTCTTCGATGATTGTCCCCGGCGTGCTCTGGGGGCTGGTGCTGTTTTCCGTGGTCAGCTGGGCGAT
CCTGCTGGTCAAGTCGGCGCAATACCTGCGCCAGAAAACCCAGAACAAGCAGTTCAGCAAAGCCTTCTGGGGCGCGCCGG
ATCTGCTGACCGCCGCCGAACACGCCAGCCAGTATCCGGGCTCGCTGGCGCGGATCGCCAGCAGCGGTTTCGAAGCCCTG
CTGGTGGAAGAATCCCCGCGCACCACCCAGCAACTGGCGCACACCATCAACCGTTCCGATCGACTGGAACGCAACCTGCG
CCAGCAGATCCAGAAGGAACGTCGCTCATTGGAAAACGGCCAGGCGATCCTCGCCAGTATCGGCAGCACCGCGCCGTTCA
TTGGCCTGTTCGGCACCGTGTGGGGAATCATGGAAGCCCTGCAAAGCATCGGCGCCAGCGGCTCGGCCAGCCTGGAAACC
GTGGCCGGGCCGATCGGCCACGCGCTGATCGCCACCGGTGTGGGGATTGCCGTCGCGGTGCCGGCGGTGCTGATTTACAA
CTTCTTCCTGCGGCGCCTGAAGCTGGCTTCGGCGGACATGGATGACTTCGCCCACGACTTCGACGCCCTTGCCTCGCGCA
GTGCGTTTTCCATCAGCCGCCAGGCCATCGCCAAATCCGCGGCCGCCGTGCGGGAGGCCAGCTGA

Upstream 100 bases:

>100_bases
CCGATCGACGGCTTCGCCACCCAGACCATCGATTTCAAATTGCCGCAATGACGGCACGACAACCGAACTCACAACCGATT
AACGCAAGCGAGGTGTAGCC

Downstream 100 bases:

>100_bases
TGTCCTTTTCCACTCAAGACAGCGATGAAGTGCTCAGCGAAATGAACGTCACGCCGCTGGTGGACGTGATGCTCGTGCTG
CTGGTGGTGTTCATCGTCAC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNDSLSSMIVPGVLWGLVLFSVVSWAILLVKSAQYLRQKTQNKQFSKAFWGAPDLLTAAEHASQYPGSLARIASSGFEAL
LVEESPRTTQQLAHTINRSDRLERNLRQQIQKERRSLENGQAILASIGSTAPFIGLFGTVWGIMEALQSIGASGSASLET
VAGPIGHALIATGVGIAVAVPAVLIYNFFLRRLKLASADMDDFAHDFDALASRSAFSISRQAIAKSAAAVREAS

Sequences:

>Translated_234_residues
MNDSLSSMIVPGVLWGLVLFSVVSWAILLVKSAQYLRQKTQNKQFSKAFWGAPDLLTAAEHASQYPGSLARIASSGFEAL
LVEESPRTTQQLAHTINRSDRLERNLRQQIQKERRSLENGQAILASIGSTAPFIGLFGTVWGIMEALQSIGASGSASLET
VAGPIGHALIATGVGIAVAVPAVLIYNFFLRRLKLASADMDDFAHDFDALASRSAFSISRQAIAKSAAAVREAS
>Mature_234_residues
MNDSLSSMIVPGVLWGLVLFSVVSWAILLVKSAQYLRQKTQNKQFSKAFWGAPDLLTAAEHASQYPGSLARIASSGFEAL
LVEESPRTTQQLAHTINRSDRLERNLRQQIQKERRSLENGQAILASIGSTAPFIGLFGTVWGIMEALQSIGASGSASLET
VAGPIGHALIATGVGIAVAVPAVLIYNFFLRRLKLASADMDDFAHDFDALASRSAFSISRQAIAKSAAAVREAS

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=219, Percent_Identity=31.5068493150685, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789381, Length=212, Percent_Identity=33.0188679245283, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25073; Mature: 25073

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSLSSMIVPGVLWGLVLFSVVSWAILLVKSAQYLRQKTQNKQFSKAFWGAPDLLTAAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHH
HASQYPGSLARIASSGFEALLVEESPRTTQQLAHTINRSDRLERNLRQQIQKERRSLENG
HHHHCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
QAILASIGSTAPFIGLFGTVWGIMEALQSIGASGSASLETVAGPIGHALIATGVGIAVAV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PAVLIYNFFLRRLKLASADMDDFAHDFDALASRSAFSISRQAIAKSAAAVREAS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDSLSSMIVPGVLWGLVLFSVVSWAILLVKSAQYLRQKTQNKQFSKAFWGAPDLLTAAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHH
HASQYPGSLARIASSGFEALLVEESPRTTQQLAHTINRSDRLERNLRQQIQKERRSLENG
HHHHCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
QAILASIGSTAPFIGLFGTVWGIMEALQSIGASGSASLETVAGPIGHALIATGVGIAVAV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PAVLIYNFFLRRLKLASADMDDFAHDFDALASRSAFSISRQAIAKSAAAVREAS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]