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The map label for this gene is qseD [H]

Identifier: 77459000

GI number: 77459000

Start: 3200793

End: 3201665

Strand: Direct

Name: qseD [H]

Synonym: Pfl01_2775

Alternate gene names: 77459000

Gene position: 3200793-3201665 (Clockwise)

Preceding gene: 77458995

Following gene: 77459002

Centisome position: 49.71

GC content: 55.9

Gene sequence:

>873_bases
TTGGAACTCGTTTGGCTTGAGGATTTTTCAGCGCTTGCGGAGTACGGCAGCTTTGTTCGGGCGGCTGAAGCGCGCCACGT
TACTCAACCTGCCTTCAGTCGCAGAGTCCGCGCTCTGGAGAATTGGATGGGTGTCGAATTGTTCATACGCACCCCCCAGG
GGGCGACGTTGACCGAGGCTGGAAGACAGATTTTGCCTAGCGCCCAAGAGGCTGCCAGACGCTTGTACCGGATGCGCTCC
GAGGCACAGGAAGTGGCTGGGATGGCCGCCAAAACACTGCAGTTTGCAGCCACTCATTCGTTGTCATTTACCTTCTTCCC
AAGGTGGTTGAGAAGTGCAGAAAATGGCGCGCCGATAGATGCCGTACGTCTGCATTCAGACAGCATGGCTGTTTGCGAGC
AGATGCTGATACACGGCCAGGTTCAATTTCTGCTTTGCCATCGCCACCCCGACGTTCCACCCCTGCTGGCCCCTGATCAG
TTCACCGGGAAAAAGGTCGGAGAGGATGTGCTCATACCCTTGGCGAGTGCCTCTGCCACGTTGGGTACGTCCCCGGAAAC
ACTGCCTTATTTGGCATATACCCAGGAATCCGGTCTAGGCCGTATCGTCGCTCACCGACTCCACGGCAAGGAAGACTACC
TTCACCTCAAGCCGCTTTTTAGCAGCCATCTTGCGGCGGTTCTGATGTCCATGGCACTGGAAAGCAAGGGCGTAGCGTGG
TTACCAAAAAGCCTGACCGAGCAGGAAATGGCTGATGGGCGGCTGGTCAGAACTCTCGACGAAAGCTGGGATATACCGTT
AGAGATTCACCTCACTCGACCTAAAGCCCCCATTAGCTTATCTGCAGAAGAATTCTGGGCCAGGCTGGCTTAA

Upstream 100 bases:

>100_bases
TGACGGGTTCCTCTTGTTGTTGGTGGCCCCACGTTATGCTTTGCGATGACACCCGCCCAATGCTATTAATGCCGCGCCCT
ATGCACAGGAGGCATTGCCC

Downstream 100 bases:

>100_bases
TAGATCCATCTTACTGACCTCCATTTTTCACTTTCTAACGGCGTTCTGGCGAGCCAGAAAACTTGGCTGTTAGTGACTGA
GTGTCTCCTATTGGCCGATA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MELVWLEDFSALAEYGSFVRAAEARHVTQPAFSRRVRALENWMGVELFIRTPQGATLTEAGRQILPSAQEAARRLYRMRS
EAQEVAGMAAKTLQFAATHSLSFTFFPRWLRSAENGAPIDAVRLHSDSMAVCEQMLIHGQVQFLLCHRHPDVPPLLAPDQ
FTGKKVGEDVLIPLASASATLGTSPETLPYLAYTQESGLGRIVAHRLHGKEDYLHLKPLFSSHLAAVLMSMALESKGVAW
LPKSLTEQEMADGRLVRTLDESWDIPLEIHLTRPKAPISLSAEEFWARLA

Sequences:

>Translated_290_residues
MELVWLEDFSALAEYGSFVRAAEARHVTQPAFSRRVRALENWMGVELFIRTPQGATLTEAGRQILPSAQEAARRLYRMRS
EAQEVAGMAAKTLQFAATHSLSFTFFPRWLRSAENGAPIDAVRLHSDSMAVCEQMLIHGQVQFLLCHRHPDVPPLLAPDQ
FTGKKVGEDVLIPLASASATLGTSPETLPYLAYTQESGLGRIVAHRLHGKEDYLHLKPLFSSHLAAVLMSMALESKGVAW
LPKSLTEQEMADGRLVRTLDESWDIPLEIHLTRPKAPISLSAEEFWARLA
>Mature_290_residues
MELVWLEDFSALAEYGSFVRAAEARHVTQPAFSRRVRALENWMGVELFIRTPQGATLTEAGRQILPSAQEAARRLYRMRS
EAQEVAGMAAKTLQFAATHSLSFTFFPRWLRSAENGAPIDAVRLHSDSMAVCEQMLIHGQVQFLLCHRHPDVPPLLAPDQ
FTGKKVGEDVLIPLASASATLGTSPETLPYLAYTQESGLGRIVAHRLHGKEDYLHLKPLFSSHLAAVLMSMALESKGVAW
LPKSLTEQEMADGRLVRTLDESWDIPLEIHLTRPKAPISLSAEEFWARLA

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=293, Percent_Identity=29.0102389078498, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI145693105, Length=142, Percent_Identity=28.169014084507, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI157672245, Length=133, Percent_Identity=33.0827067669173, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788297, Length=161, Percent_Identity=30.4347826086957, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32278; Mature: 32278

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVWLEDFSALAEYGSFVRAAEARHVTQPAFSRRVRALENWMGVELFIRTPQGATLTEA
CEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
GRQILPSAQEAARRLYRMRSEAQEVAGMAAKTLQFAATHSLSFTFFPRWLRSAENGAPID
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCE
AVRLHSDSMAVCEQMLIHGQVQFLLCHRHPDVPPLLAPDQFTGKKVGEDVLIPLASASAT
EEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
LGTSPETLPYLAYTQESGLGRIVAHRLHGKEDYLHLKPLFSSHLAAVLMSMALESKGVAW
CCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEE
LPKSLTEQEMADGRLVRTLDESWDIPLEIHLTRPKAPISLSAEEFWARLA
CCHHHHHHHHHCCHHEEHHHHCCCCCEEEEEECCCCCCEECHHHHHHHCC
>Mature Secondary Structure
MELVWLEDFSALAEYGSFVRAAEARHVTQPAFSRRVRALENWMGVELFIRTPQGATLTEA
CEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
GRQILPSAQEAARRLYRMRSEAQEVAGMAAKTLQFAATHSLSFTFFPRWLRSAENGAPID
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCE
AVRLHSDSMAVCEQMLIHGQVQFLLCHRHPDVPPLLAPDQFTGKKVGEDVLIPLASASAT
EEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
LGTSPETLPYLAYTQESGLGRIVAHRLHGKEDYLHLKPLFSSHLAAVLMSMALESKGVAW
CCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEE
LPKSLTEQEMADGRLVRTLDESWDIPLEIHLTRPKAPISLSAEEFWARLA
CCHHHHHHHHHCCHHEEHHHHCCCCCEEEEEECCCCCCEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]