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The map label for this gene is fdoG [H]

Identifier: 77458923

GI number: 77458923

Start: 3107514

End: 3109976

Strand: Direct

Name: fdoG [H]

Synonym: Pfl01_2698

Alternate gene names: 77458923

Gene position: 3107514-3109976 (Clockwise)

Preceding gene: 77458922

Following gene: 77458924

Centisome position: 48.27

GC content: 61.35

Gene sequence:

>2463_bases
GTGGCAAGTCTTGCCCCGACGTACGGCCGTGGAGCCATGACCAACACCTGGACCGATATCGCCAATGCGAATCTGATCCT
GGTGATGGGCGGCAACGCAGCAGAAGCCCACCCTTGTGGCTTCAAATGGGTGACCGAAGCCAAGGCGCACAACGCCGCGC
GGCTGATTGTGGTCGATCCGAGGTTTACCCGGACCGCATCCGTGGCCGATTACTACGCGCCGATTCGCACCGGCAGCGAC
ATCGCGTTCATGGGCGGGCTGATCAATTACCTGCTGACCGAGGACAAGATCCAGCACGAATACGTGCGCAACTACACCGA
CGTATCGTTCATTGTCAGAGCCGGATTCGGCTTCGAGGACGGGCTGTTCACCGGTTACGACGCGGCCAAGCGCAGCTACA
CCGACAAATCCACCTGGGGTTACGAACTGGGCGAGGACGGCTTCGTCAAAGTCGACCCGACCCTGCAGGACCCGCGCTGC
GTCTATCAACTGATGAAGCAGCATTACAGCCGCTACAACATCGACCTGGCGAGCCAGATCTGCGGCATGCCGGTCGATGC
GATGAAAAAGATCTGGGAGGAAATCGCCACTTGCTCGGCGCCGGGCAAGACCATGACGATTCTTTATGCACTGGGCTGGA
CCCAGCACTCGATCGGCTCGCAGATCATTCGCAGCGCGGCGATGGTGCAACTGCTGCTGGGTAACGTCGGCATGCCCGGC
GGCGGGGTCAATGCTTTGCGCGGGCACTCGAACATTCAGGGCCTGACCGACCTTGGTCTGCTGTCCAACGCGCTGCCGGG
TTACCTGACCTTGCCGACCGACGCCGAGCAGGATTACGCGGCCTTCATCCATAAACGCACGCAAGTCCCGCTGCGGCCGG
GGCAATTGTCCTACTGGCAGAACTACAGCAAATTCCACGTCAGCCTGATGAAAGCCTGGTACGGCGCCAATGCCACCGCC
GAGAATCAGTGGGCCTACCACTACTTGCCGAAACTCGACATCCCCAACTACGACATCCTCAAGGTGTTCGACCTGATGGG
GCAGGGCAAGGTCAACGGCTACATGTGTCAGGGCTTCAACCCGATTGCCGCGCTGCCGGACAAGAACCGGGTGATGGCGG
CACTGGCCAAACTGAAATGGCTGGTGGTGATGGACCCGCTGGCCACCGAAACTTCGCAGTTCTGGGAACACGTCGGGCCA
TTCAACGATGTGAAGAGCGCCGACATCCAGACCGAAGTCATCCGCCTGCCAACCACCTGTTTTGCCGAAGAGGACGGCTC
GCTGGTCAACAGCAGCCGCTGGCTGCAATGGCATTGGAAAGGCGCCGACGGCCCCGGCGAGGCGCGCACCGACGTGCAAA
TCATGAGTGCGCTGTTCCTGCGTCTGCGTGAGCGATATCAGGCGGAGGGCGGCAAATTCGCCGACCCGCTGTTGAAACTG
TCGTGGCCGTACAAGATCGCCGAAGAACCCTCGCCGGAAGAGATCGCCAAAGAGGTCAACGGCTACGCCACCACCGATTT
CACCGACGCCACGGGTGCGGCGATCAAGGGCAATTCGCAACTGGCCGGGTTCGCCCAGCTCAAGGATGACGGCAGTACCG
CGTCCGGCTGCTGGATTTTCTGCGGCAGCTGGACCGAAGCCGGCAACCAGATGGCCCGCCGCGACAACAACGACCCTTAC
GGCATGCATCAGCATCAAGGCTGGGCATGGGCCTGGCCGGCCAACCGGCGGATTCTCTATAACCGCGCTTCGGCGGACGT
CGCCGGCAAGCCGTGGGATCCGAAAAAGCGCCTGGTCTGGTGGAACGGCAAGGCCTGGGGCGGCACCGATGTGCCGGATT
ACAAGGCCGACGTGCCGCCGGAAGCCGGGATGAACCCGTTCATCATGAACCCCGAAGGCGTGGCGCGGTTCTTCGCCGTC
GACAAGATGAACGAAGGGCCATTTCCCGAGCATTACGAGCCGTTCGAAACGCCGATCGGCATCAACCCGCTGCACCCGGA
CAACAAGAAAGCCACCAGCAACCCGGCGGCACGGATCTTCGATTCGGTGTGGGACAGCCTCGGCGTGGCCAAGGATTACC
CGTACGCCGCCACCAGCTACCGGTTGACCGAGCACTTCCACTTCTGGAGCAAGCACTGCAAGTTGAACGCGATTGCTCAA
CCCGAGCAATTCGTGGAAATCGGCGAGGTGTTGGCCAAAGAGAAAGGCATCGTCGCCGGGGATCGGGTTCGCGTGAGCAG
CAAGCGCGGGTTCATTGAAGCGGTGGCGGTGGTGACCAAAAGGATCCGGCCGTTGCAGGTCAACAACCAGGTGGTGCACC
AGATCGGCATTCCGCTGCACTGGGGCTTCACCGGCCTGACGCGCCACGGTTACCTGACCAACACCCTGGTGCCGTTTCTC
GGCGATGGCAATACACAGACCCCGGAATCCAAGTCATTCCTGGTCAACGTGGAGAAGCTCTGA

Upstream 100 bases:

>100_bases
GGCGGCGTCCAACGAAGCGGGTTACATCACCCACAAGGTGGTGCGCAGTCTCGGCATGCTGGGGTTCGATAACCAGGCGC
GTGTCTGACACGGCCCGACG

Downstream 100 bases:

>100_bases
TGGAGAATCTTTAGATGGCCAGCCAAGACATCATTGCCCGCTCGGCCACCACCACGCCGGCGCCTTCGATACGCGGCCAG
GAACAGGTGGCCAAGCTGAT

Product: formate dehydrogenase subunit alpha

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 820; Mature: 819

Protein sequence:

>820_residues
MASLAPTYGRGAMTNTWTDIANANLILVMGGNAAEAHPCGFKWVTEAKAHNAARLIVVDPRFTRTASVADYYAPIRTGSD
IAFMGGLINYLLTEDKIQHEYVRNYTDVSFIVRAGFGFEDGLFTGYDAAKRSYTDKSTWGYELGEDGFVKVDPTLQDPRC
VYQLMKQHYSRYNIDLASQICGMPVDAMKKIWEEIATCSAPGKTMTILYALGWTQHSIGSQIIRSAAMVQLLLGNVGMPG
GGVNALRGHSNIQGLTDLGLLSNALPGYLTLPTDAEQDYAAFIHKRTQVPLRPGQLSYWQNYSKFHVSLMKAWYGANATA
ENQWAYHYLPKLDIPNYDILKVFDLMGQGKVNGYMCQGFNPIAALPDKNRVMAALAKLKWLVVMDPLATETSQFWEHVGP
FNDVKSADIQTEVIRLPTTCFAEEDGSLVNSSRWLQWHWKGADGPGEARTDVQIMSALFLRLRERYQAEGGKFADPLLKL
SWPYKIAEEPSPEEIAKEVNGYATTDFTDATGAAIKGNSQLAGFAQLKDDGSTASGCWIFCGSWTEAGNQMARRDNNDPY
GMHQHQGWAWAWPANRRILYNRASADVAGKPWDPKKRLVWWNGKAWGGTDVPDYKADVPPEAGMNPFIMNPEGVARFFAV
DKMNEGPFPEHYEPFETPIGINPLHPDNKKATSNPAARIFDSVWDSLGVAKDYPYAATSYRLTEHFHFWSKHCKLNAIAQ
PEQFVEIGEVLAKEKGIVAGDRVRVSSKRGFIEAVAVVTKRIRPLQVNNQVVHQIGIPLHWGFTGLTRHGYLTNTLVPFL
GDGNTQTPESKSFLVNVEKL

Sequences:

>Translated_820_residues
MASLAPTYGRGAMTNTWTDIANANLILVMGGNAAEAHPCGFKWVTEAKAHNAARLIVVDPRFTRTASVADYYAPIRTGSD
IAFMGGLINYLLTEDKIQHEYVRNYTDVSFIVRAGFGFEDGLFTGYDAAKRSYTDKSTWGYELGEDGFVKVDPTLQDPRC
VYQLMKQHYSRYNIDLASQICGMPVDAMKKIWEEIATCSAPGKTMTILYALGWTQHSIGSQIIRSAAMVQLLLGNVGMPG
GGVNALRGHSNIQGLTDLGLLSNALPGYLTLPTDAEQDYAAFIHKRTQVPLRPGQLSYWQNYSKFHVSLMKAWYGANATA
ENQWAYHYLPKLDIPNYDILKVFDLMGQGKVNGYMCQGFNPIAALPDKNRVMAALAKLKWLVVMDPLATETSQFWEHVGP
FNDVKSADIQTEVIRLPTTCFAEEDGSLVNSSRWLQWHWKGADGPGEARTDVQIMSALFLRLRERYQAEGGKFADPLLKL
SWPYKIAEEPSPEEIAKEVNGYATTDFTDATGAAIKGNSQLAGFAQLKDDGSTASGCWIFCGSWTEAGNQMARRDNNDPY
GMHQHQGWAWAWPANRRILYNRASADVAGKPWDPKKRLVWWNGKAWGGTDVPDYKADVPPEAGMNPFIMNPEGVARFFAV
DKMNEGPFPEHYEPFETPIGINPLHPDNKKATSNPAARIFDSVWDSLGVAKDYPYAATSYRLTEHFHFWSKHCKLNAIAQ
PEQFVEIGEVLAKEKGIVAGDRVRVSSKRGFIEAVAVVTKRIRPLQVNNQVVHQIGIPLHWGFTGLTRHGYLTNTLVPFL
GDGNTQTPESKSFLVNVEKL
>Mature_819_residues
ASLAPTYGRGAMTNTWTDIANANLILVMGGNAAEAHPCGFKWVTEAKAHNAARLIVVDPRFTRTASVADYYAPIRTGSDI
AFMGGLINYLLTEDKIQHEYVRNYTDVSFIVRAGFGFEDGLFTGYDAAKRSYTDKSTWGYELGEDGFVKVDPTLQDPRCV
YQLMKQHYSRYNIDLASQICGMPVDAMKKIWEEIATCSAPGKTMTILYALGWTQHSIGSQIIRSAAMVQLLLGNVGMPGG
GVNALRGHSNIQGLTDLGLLSNALPGYLTLPTDAEQDYAAFIHKRTQVPLRPGQLSYWQNYSKFHVSLMKAWYGANATAE
NQWAYHYLPKLDIPNYDILKVFDLMGQGKVNGYMCQGFNPIAALPDKNRVMAALAKLKWLVVMDPLATETSQFWEHVGPF
NDVKSADIQTEVIRLPTTCFAEEDGSLVNSSRWLQWHWKGADGPGEARTDVQIMSALFLRLRERYQAEGGKFADPLLKLS
WPYKIAEEPSPEEIAKEVNGYATTDFTDATGAAIKGNSQLAGFAQLKDDGSTASGCWIFCGSWTEAGNQMARRDNNDPYG
MHQHQGWAWAWPANRRILYNRASADVAGKPWDPKKRLVWWNGKAWGGTDVPDYKADVPPEAGMNPFIMNPEGVARFFAVD
KMNEGPFPEHYEPFETPIGINPLHPDNKKATSNPAARIFDSVWDSLGVAKDYPYAATSYRLTEHFHFWSKHCKLNAIAQP
EQFVEIGEVLAKEKGIVAGDRVRVSSKRGFIEAVAVVTKRIRPLQVNNQVVHQIGIPLHWGFTGLTRHGYLTNTLVPFLG
DGNTQTPESKSFLVNVEKL

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=822, Percent_Identity=63.3819951338199, Blast_Score=1098, Evalue=0.0,
Organism=Escherichia coli, GI3868719, Length=820, Percent_Identity=61.0975609756098, Blast_Score=1074, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=462, Percent_Identity=25.1082251082251, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87081797, Length=250, Percent_Identity=29.2, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1787870, Length=235, Percent_Identity=30.6382978723404, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI171474008, Length=253, Percent_Identity=28.4584980237154, Blast_Score=76, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 91253; Mature: 91122

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLAPTYGRGAMTNTWTDIANANLILVMGGNAAEAHPCGFKWVTEAKAHNAARLIVVDP
CCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEEHHCCCCCEEEEEECC
RFTRTASVADYYAPIRTGSDIAFMGGLINYLLTEDKIQHEYVRNYTDVSFIVRAGFGFED
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
GLFTGYDAAKRSYTDKSTWGYELGEDGFVKVDPTLQDPRCVYQLMKQHYSRYNIDLASQI
CCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHH
CGMPVDAMKKIWEEIATCSAPGKTMTILYALGWTQHSIGSQIIRSAAMVQLLLGNVGMPG
HCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCC
GGVNALRGHSNIQGLTDLGLLSNALPGYLTLPTDAEQDYAAFIHKRTQVPLRPGQLSYWQ
CCCHHHCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHH
NYSKFHVSLMKAWYGANATAENQWAYHYLPKLDIPNYDILKVFDLMGQGKVNGYMCQGFN
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCEEECCCC
PIAALPDKNRVMAALAKLKWLVVMDPLATETSQFWEHVGPFNDVKSADIQTEVIRLPTTC
CCCCCCCCHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCE
FAEEDGSLVNSSRWLQWHWKGADGPGEARTDVQIMSALFLRLRERYQAEGGKFADPLLKL
ECCCCCCEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEE
SWPYKIAEEPSPEEIAKEVNGYATTDFTDATGAAIKGNSQLAGFAQLKDDGSTASGCWIF
CCCEECCCCCCHHHHHHHHCCCEECCCCCCCCCEEECCCCCCEEEEECCCCCCCCCEEEE
CGSWTEAGNQMARRDNNDPYGMHQHQGWAWAWPANRRILYNRASADVAGKPWDPKKRLVW
ECCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEE
WNGKAWGGTDVPDYKADVPPEAGMNPFIMNPEGVARFFAVDKMNEGPFPEHYEPFETPIG
ECCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
INPLHPDNKKATSNPAARIFDSVWDSLGVAKDYPYAATSYRLTEHFHFWSKHCKLNAIAQ
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCC
PEQFVEIGEVLAKEKGIVAGDRVRVSSKRGFIEAVAVVTKRIRPLQVNNQVVHQIGIPLH
HHHHHHHHHHHHHCCCCEECCEEEECCCCCHHHHHHHHHHCCCCEECCCHHHHHCCCEEE
WGFTGLTRHGYLTNTLVPFLGDGNTQTPESKSFLVNVEKL
ECCHHHCCCCCHHHCHHHEECCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
ASLAPTYGRGAMTNTWTDIANANLILVMGGNAAEAHPCGFKWVTEAKAHNAARLIVVDP
CCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEEHHCCCCCEEEEEECC
RFTRTASVADYYAPIRTGSDIAFMGGLINYLLTEDKIQHEYVRNYTDVSFIVRAGFGFED
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
GLFTGYDAAKRSYTDKSTWGYELGEDGFVKVDPTLQDPRCVYQLMKQHYSRYNIDLASQI
CCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHH
CGMPVDAMKKIWEEIATCSAPGKTMTILYALGWTQHSIGSQIIRSAAMVQLLLGNVGMPG
HCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCC
GGVNALRGHSNIQGLTDLGLLSNALPGYLTLPTDAEQDYAAFIHKRTQVPLRPGQLSYWQ
CCCHHHCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHH
NYSKFHVSLMKAWYGANATAENQWAYHYLPKLDIPNYDILKVFDLMGQGKVNGYMCQGFN
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCEEECCCC
PIAALPDKNRVMAALAKLKWLVVMDPLATETSQFWEHVGPFNDVKSADIQTEVIRLPTTC
CCCCCCCCHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCE
FAEEDGSLVNSSRWLQWHWKGADGPGEARTDVQIMSALFLRLRERYQAEGGKFADPLLKL
ECCCCCCEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEE
SWPYKIAEEPSPEEIAKEVNGYATTDFTDATGAAIKGNSQLAGFAQLKDDGSTASGCWIF
CCCEECCCCCCHHHHHHHHCCCEECCCCCCCCCEEECCCCCCEEEEECCCCCCCCCEEEE
CGSWTEAGNQMARRDNNDPYGMHQHQGWAWAWPANRRILYNRASADVAGKPWDPKKRLVW
ECCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEE
WNGKAWGGTDVPDYKADVPPEAGMNPFIMNPEGVARFFAVDKMNEGPFPEHYEPFETPIG
ECCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
INPLHPDNKKATSNPAARIFDSVWDSLGVAKDYPYAATSYRLTEHFHFWSKHCKLNAIAQ
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCC
PEQFVEIGEVLAKEKGIVAGDRVRVSSKRGFIEAVAVVTKRIRPLQVNNQVVHQIGIPLH
HHHHHHHHHHHHHCCCCEECCEEEECCCCCHHHHHHHHHHCCCCEECCCHHHHHCCCEEE
WGFTGLTRHGYLTNTLVPFLGDGNTQTPESKSFLVNVEKL
ECCHHHCCCCCHHHCHHHEECCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]