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The map label for this gene is torS [H]

Identifier: 77458874

GI number: 77458874

Start: 3036293

End: 3037507

Strand: Direct

Name: torS [H]

Synonym: Pfl01_2649

Alternate gene names: 77458874

Gene position: 3036293-3037507 (Clockwise)

Preceding gene: 77458873

Following gene: 77458875

Centisome position: 47.16

GC content: 59.01

Gene sequence:

>1215_bases
ATGCTGAGTAATATCCAGGCAAAACTGCTGATCGTCGACGATCTGCCCGAGAACCTGCTGGCCCTCGAAGCGCTGATCAA
ACGCGAAGACCGCACCGTCTATAAAGCGTTATCGGCGGACGAAGCGCTGTCGCTGCTGCTGCAACACGAATTCGCCATGG
CCATTCTCGACGTGCAGATGCCCGGCATGAACGGCTTCGAACTGGCCGAGCTGATGCGCGGCACCGAGAAAACCAAGAAC
ATCCCGATCATCTTCGTCAGCGCTGCCGGCCGTGAACTCAATTACGCGTTCAAGGGCTATGAAAGCGGCGCGGTAGACTT
CCTGCACAAACCGCTGGATATCCACGCGGTGAAGAGCAAGGTCAATGTCTTCGTCGACCTTTACCGCCAGAGCAAGGCGA
TGAAGCAACAGGTCGAAGCCCTTGAGCAGAGCCGCCGCGAACAGGAAGCGCTGTTGCTGCAACTGCAAAGCACCCAGGGC
GAACTGGAGCAAGCGGTACGCATGCGCGACGATTTCATGTCGATCGTCGCCCACGAAGTGCGTACGCCGCTTAACGGCCT
TATCCTCGAAACCCAACTGCGCAAGATGCACCTGGCTCGGGACAACGCCGCCGCGTTCACCCTCGACAAGATGCACGCCA
TGGTCGACCGCGACGAGCGCCAGATCAAAAGCCTGATCCGCTTGATCGAGGACATGCTCGACGTGTCGCGGATCCGCACC
GGCAAGCTGTCGATCCGACCGAGTCGCTTCGACCTCGCGCAGCTGGTGGGCAGTCTGCTGGAGAATTTCGCCCAACAGAT
CGAGGCCGCCGAGACTGAGGTCAGTTTCACTGCCGCCGAACCGGTGGAAGGCCAGTGGGACGAATTCCGCATTGAGCAGG
TGGTGTCGAACCTGCTGACCAACGCCTTGCGTTATGGCGGTAAAAGTCCGATCCAGGTACGGGTCTATCGCGAAGGCAAT
GAAGCCCGGGTTGAAGTTCAGGATCAGGGCATCGGCATCAGCGAGGAGAACCAGAAACGCATTTTTCAACAGTTCGAACG
GGTTTCCGCCAAAACGGTGGTGGCCGGCCTCGGGCTGGGGCTGTTCATCTCCGAGCAGATCGTCGCCGCCCATGGCGGCT
CCATCGTCGTCGAAAGCAAGATCAACGAGGGCGCCCTGTTTCGCGTTTGTCTGCCGCTCCAGGAAAACGGCAAAACAAAC
GCAACCTCTGAGTGA

Upstream 100 bases:

>100_bases
TCGCCACCATGCCTCGCGCGGCACTGAAAACGCATCAACCGGATTACATACTTCCCATACACGGCATCGGCCGTCTGCTT
GTCGAGCTGGAACGAATCGC

Downstream 100 bases:

>100_bases
CCACACGGTCGTATCAGCAGCTATTGACCGAACAAAGGCTTCCCATGAGCGTAGATGCACAAGATGTAGTACTCGTCGTC
GAGGACGAACCGGTGATCCT

Product: response regulator receiver Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MLSNIQAKLLIVDDLPENLLALEALIKREDRTVYKALSADEALSLLLQHEFAMAILDVQMPGMNGFELAELMRGTEKTKN
IPIIFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSKVNVFVDLYRQSKAMKQQVEALEQSRREQEALLLQLQSTQG
ELEQAVRMRDDFMSIVAHEVRTPLNGLILETQLRKMHLARDNAAAFTLDKMHAMVDRDERQIKSLIRLIEDMLDVSRIRT
GKLSIRPSRFDLAQLVGSLLENFAQQIEAAETEVSFTAAEPVEGQWDEFRIEQVVSNLLTNALRYGGKSPIQVRVYREGN
EARVEVQDQGIGISEENQKRIFQQFERVSAKTVVAGLGLGLFISEQIVAAHGGSIVVESKINEGALFRVCLPLQENGKTN
ATSE

Sequences:

>Translated_404_residues
MLSNIQAKLLIVDDLPENLLALEALIKREDRTVYKALSADEALSLLLQHEFAMAILDVQMPGMNGFELAELMRGTEKTKN
IPIIFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSKVNVFVDLYRQSKAMKQQVEALEQSRREQEALLLQLQSTQG
ELEQAVRMRDDFMSIVAHEVRTPLNGLILETQLRKMHLARDNAAAFTLDKMHAMVDRDERQIKSLIRLIEDMLDVSRIRT
GKLSIRPSRFDLAQLVGSLLENFAQQIEAAETEVSFTAAEPVEGQWDEFRIEQVVSNLLTNALRYGGKSPIQVRVYREGN
EARVEVQDQGIGISEENQKRIFQQFERVSAKTVVAGLGLGLFISEQIVAAHGGSIVVESKINEGALFRVCLPLQENGKTN
ATSE
>Mature_404_residues
MLSNIQAKLLIVDDLPENLLALEALIKREDRTVYKALSADEALSLLLQHEFAMAILDVQMPGMNGFELAELMRGTEKTKN
IPIIFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSKVNVFVDLYRQSKAMKQQVEALEQSRREQEALLLQLQSTQG
ELEQAVRMRDDFMSIVAHEVRTPLNGLILETQLRKMHLARDNAAAFTLDKMHAMVDRDERQIKSLIRLIEDMLDVSRIRT
GKLSIRPSRFDLAQLVGSLLENFAQQIEAAETEVSFTAAEPVEGQWDEFRIEQVVSNLLTNALRYGGKSPIQVRVYREGN
EARVEVQDQGIGISEENQKRIFQQFERVSAKTVVAGLGLGLFISEQIVAAHGGSIVVESKINEGALFRVCLPLQENGKTN
ATSE

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates torR via a four-step phosphorelay. When TMAO is removed,

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=285, Percent_Identity=31.5789473684211, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=30.6034482758621, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789149, Length=268, Percent_Identity=28.3582089552239, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=28.8065843621399, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=26.6129032258064, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788713, Length=259, Percent_Identity=23.5521235521236, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=28.6290322580645, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=31.4159292035398, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=27.710843373494, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789808, Length=239, Percent_Identity=28.8702928870293, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=29.0909090909091, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=29.5275590551181, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=25.9911894273128, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=28.9915966386555, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788279, Length=223, Percent_Identity=25.5605381165919, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87082128, Length=241, Percent_Identity=26.5560165975104, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014302
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45304; Mature: 45304

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNIQAKLLIVDDLPENLLALEALIKREDRTVYKALSADEALSLLLQHEFAMAILDVQM
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
PGMNGFELAELMRGTEKTKNIPIIFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSK
CCCCCHHHHHHHHCCHHCCCCCEEEEECCCCEEEHEECCCCCCCHHHHCCCCHHHHHHHH
VNVFVDLYRQSKAMKQQVEALEQSRREQEALLLQLQSTQGELEQAVRMRDDFMSIVAHEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RTPLNGLILETQLRKMHLARDNAAAFTLDKMHAMVDRDERQIKSLIRLIEDMLDVSRIRT
HCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
GKLSIRPSRFDLAQLVGSLLENFAQQIEAAETEVSFTAAEPVEGQWDEFRIEQVVSNLLT
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHH
NALRYGGKSPIQVRVYREGNEARVEVQDQGIGISEENQKRIFQQFERVSAKTVVAGLGLG
HHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
LFISEQIVAAHGGSIVVESKINEGALFRVCLPLQENGKTNATSE
HHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MLSNIQAKLLIVDDLPENLLALEALIKREDRTVYKALSADEALSLLLQHEFAMAILDVQM
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
PGMNGFELAELMRGTEKTKNIPIIFVSAAGRELNYAFKGYESGAVDFLHKPLDIHAVKSK
CCCCCHHHHHHHHCCHHCCCCCEEEEECCCCEEEHEECCCCCCCHHHHCCCCHHHHHHHH
VNVFVDLYRQSKAMKQQVEALEQSRREQEALLLQLQSTQGELEQAVRMRDDFMSIVAHEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RTPLNGLILETQLRKMHLARDNAAAFTLDKMHAMVDRDERQIKSLIRLIEDMLDVSRIRT
HCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
GKLSIRPSRFDLAQLVGSLLENFAQQIEAAETEVSFTAAEPVEGQWDEFRIEQVVSNLLT
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHH
NALRYGGKSPIQVRVYREGNEARVEVQDQGIGISEENQKRIFQQFERVSAKTVVAGLGLG
HHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
LFISEQIVAAHGGSIVVESKINEGALFRVCLPLQENGKTNATSE
HHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]