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The map label for this gene is oprD [H]

Identifier: 77458857

GI number: 77458857

Start: 3012598

End: 3013899

Strand: Direct

Name: oprD [H]

Synonym: Pfl01_2632

Alternate gene names: 77458857

Gene position: 3012598-3013899 (Clockwise)

Preceding gene: 77458849

Following gene: 77458871

Centisome position: 46.79

GC content: 59.06

Gene sequence:

>1302_bases
ATGCGTCCCCCATTTCCCCTCATCACCCCGCGCCAGTCGCTTGGCTTCGGAGCCTTTGTGCTGTGCGCCGGTTTTACCGC
ACAGGTCCAGGCCAGCGGTTTTTTCGAAGACACCACGGCGAAGATCGAGTCGCGCACGGTGTACTTCAACCGCGATTTCC
GTGACGGGCACACCTCCAGTGATCAGGGCGCGTCCAAGCGCGAAGAGTCGGCGCAGGGTTTCATTCTCAATCTGCAATCG
GGCTACACCGAAGGCACCGTCGGTTTCGGGATCGATGCGCTGGGCATGGCGGGATTCCAGCTCGATTCCAGCCCGGATCG
CAGCAACAGCGGCTTGTTGCCGTCCAGCGGCGACAACCCGCGCGGCTCGAAAGGTCAGTACGCGAAAATGGGCCTGACCG
CCAAGGTCAAAGTCTCGGACACGGTGCTGAAATACGGCGCACTGCTGCCGGATCTGCCGTTGCTCAAGTACAACGACGGT
CGCCTGCTGCCGACCATGTTCAACGGTGCGATGCTGACCTCCAAAGAGGTGAAGGACCTGACCTTCATGGCCGCGCGTCT
GGACAAGTACACCGCCCGGGACTCGAGCGATTCGCAAGACATCCGCGTGCACTGCAAGAACAAGCGCTATGCCTGCAACA
CCACCGCCGATCATTTCGACATGTACGGCTTCGACTACAAGATCAACGATCGCCTGACCGCGCAGTACCACTACGCCGAG
CTGGAAGACATCTATCGCCAGCATTTCGTGGGGCTGTTGGCCAATCAGCCGCTGGGTGACGGCGTGTTGAAAGCCGATCT
GCGTTTGCTGAAAAGCGCCGACAGCGGCGATGCCAAAGCGGGCTCCATCGACAACCGCGCCTTGAGCGGCATGCTGTCAT
ACGGCATCAGCGGTCACACCTTCAGCGCAGGCTGGCAGCGCATGAACGGCGACAATTCGATGCCGTATCTGGATGGCAGC
AACCCGTATCTGGTGAACTACGTGCAGGTCAACGACTTCGCCGCCGCGCAGGAACGTTCCTGGCAGTTGCGTTACGACTA
TGACTTCAAGGCGATCGGCATCAACGGCCTGAGCTTCCTGACCCGTTACGTGAACGGTGATCACATCAAAGTTCCGGGCA
GCGATCAGGAAGGCAAAGAGTGGGAACGCGACAGCGAGTTGAAGTACGTGATTCAGAGCGGCACGTTCAAGGACGTCAGC
CTGCGTTTGCGTAATGCGACGTACCGGACGAACTACGAGAAGTTTGCCCGGGACGTGGATGAGACCCGGTTGATTGTGAG
TTACAACTTTTCGGTGTTGTAA

Upstream 100 bases:

>100_bases
CCCGCGTGTTCACTGCCTCCCGGTTCTTAACTGGTCCGGGACGGGAGCTATTTCTGGTTGTTTGCGCCTCTGCGCAATCG
TTGTTCTGTTGGAGTTTTCA

Downstream 100 bases:

>100_bases
ATCCGCGCCAAAAAAAACCATCGCGAGTTAACTCGTGATGGTTTTTTTTGGCTTGGGATCAGAGCCAATGCCAGAACCGG
CTCCAGAACCCGCGATTCAA

Product: outer membrane porin

Products: NA

Alternate protein names: Imipenem/basic amino acid-specific outer membrane pore; Outer membrane protein D2 [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRPPFPLITPRQSLGFGAFVLCAGFTAQVQASGFFEDTTAKIESRTVYFNRDFRDGHTSSDQGASKREESAQGFILNLQS
GYTEGTVGFGIDALGMAGFQLDSSPDRSNSGLLPSSGDNPRGSKGQYAKMGLTAKVKVSDTVLKYGALLPDLPLLKYNDG
RLLPTMFNGAMLTSKEVKDLTFMAARLDKYTARDSSDSQDIRVHCKNKRYACNTTADHFDMYGFDYKINDRLTAQYHYAE
LEDIYRQHFVGLLANQPLGDGVLKADLRLLKSADSGDAKAGSIDNRALSGMLSYGISGHTFSAGWQRMNGDNSMPYLDGS
NPYLVNYVQVNDFAAAQERSWQLRYDYDFKAIGINGLSFLTRYVNGDHIKVPGSDQEGKEWERDSELKYVIQSGTFKDVS
LRLRNATYRTNYEKFARDVDETRLIVSYNFSVL

Sequences:

>Translated_433_residues
MRPPFPLITPRQSLGFGAFVLCAGFTAQVQASGFFEDTTAKIESRTVYFNRDFRDGHTSSDQGASKREESAQGFILNLQS
GYTEGTVGFGIDALGMAGFQLDSSPDRSNSGLLPSSGDNPRGSKGQYAKMGLTAKVKVSDTVLKYGALLPDLPLLKYNDG
RLLPTMFNGAMLTSKEVKDLTFMAARLDKYTARDSSDSQDIRVHCKNKRYACNTTADHFDMYGFDYKINDRLTAQYHYAE
LEDIYRQHFVGLLANQPLGDGVLKADLRLLKSADSGDAKAGSIDNRALSGMLSYGISGHTFSAGWQRMNGDNSMPYLDGS
NPYLVNYVQVNDFAAAQERSWQLRYDYDFKAIGINGLSFLTRYVNGDHIKVPGSDQEGKEWERDSELKYVIQSGTFKDVS
LRLRNATYRTNYEKFARDVDETRLIVSYNFSVL
>Mature_433_residues
MRPPFPLITPRQSLGFGAFVLCAGFTAQVQASGFFEDTTAKIESRTVYFNRDFRDGHTSSDQGASKREESAQGFILNLQS
GYTEGTVGFGIDALGMAGFQLDSSPDRSNSGLLPSSGDNPRGSKGQYAKMGLTAKVKVSDTVLKYGALLPDLPLLKYNDG
RLLPTMFNGAMLTSKEVKDLTFMAARLDKYTARDSSDSQDIRVHCKNKRYACNTTADHFDMYGFDYKINDRLTAQYHYAE
LEDIYRQHFVGLLANQPLGDGVLKADLRLLKSADSGDAKAGSIDNRALSGMLSYGISGHTFSAGWQRMNGDNSMPYLDGS
NPYLVNYVQVNDFAAAQERSWQLRYDYDFKAIGINGLSFLTRYVNGDHIKVPGSDQEGKEWERDSELKYVIQSGTFKDVS
LRLRNATYRTNYEKFARDVDETRLIVSYNFSVL

Specific function: Porin with a specificity for basic amino acids. Also possesses serine protease activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oprD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005318 [H]

Pfam domain/function: PF03573 OprD [H]

EC number: NA

Molecular weight: Translated: 48255; Mature: 48255

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPFPLITPRQSLGFGAFVLCAGFTAQVQASGFFEDTTAKIESRTVYFNRDFRDGHTSS
CCCCCCCCCCCHHCCCCEEEECCCCEEEEEECCCCCCCHHEEEEEEEEEECCCCCCCCCC
DQGASKREESAQGFILNLQSGYTEGTVGFGIDALGMAGFQLDSSPDRSNSGLLPSSGDNP
CCCCCHHHHCCCEEEEEECCCCCCCCCCCCCHHHCCCCEEECCCCCCCCCCCCCCCCCCC
RGSKGQYAKMGLTAKVKVSDTVLKYGALLPDLPLLKYNDGRLLPTMFNGAMLTSKEVKDL
CCCCCCEEEECCEEEEEEHHHHHHHHHHCCCCCEEEECCCEECHHHHCCEEEECHHHHHH
TFMAARLDKYTARDSSDSQDIRVHCKNKRYACNTTADHFDMYGFDYKINDRLTAQYHYAE
HHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCCCCEECCCEEEECCEEEEEEEHHH
LEDIYRQHFVGLLANQPLGDGVLKADLRLLKSADSGDAKAGSIDNRALSGMLSYGISGHT
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCE
FSAGWQRMNGDNSMPYLDGSNPYLVNYVQVNDFAAAQERSWQLRYDYDFKAIGINGLSFL
ECCCHHCCCCCCCCCEECCCCCEEEEEEEECCCHHHHCCCEEEEEECCEEEECCCHHHHH
TRYVNGDHIKVPGSDQEGKEWERDSELKYVIQSGTFKDVSLRLRNATYRTNYEKFARDVD
HHHCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEEECCEEECCHHHHHCCCC
ETRLIVSYNFSVL
CCEEEEEECCEEC
>Mature Secondary Structure
MRPPFPLITPRQSLGFGAFVLCAGFTAQVQASGFFEDTTAKIESRTVYFNRDFRDGHTSS
CCCCCCCCCCCHHCCCCEEEECCCCEEEEEECCCCCCCHHEEEEEEEEEECCCCCCCCCC
DQGASKREESAQGFILNLQSGYTEGTVGFGIDALGMAGFQLDSSPDRSNSGLLPSSGDNP
CCCCCHHHHCCCEEEEEECCCCCCCCCCCCCHHHCCCCEEECCCCCCCCCCCCCCCCCCC
RGSKGQYAKMGLTAKVKVSDTVLKYGALLPDLPLLKYNDGRLLPTMFNGAMLTSKEVKDL
CCCCCCEEEECCEEEEEEHHHHHHHHHHCCCCCEEEECCCEECHHHHCCEEEECHHHHHH
TFMAARLDKYTARDSSDSQDIRVHCKNKRYACNTTADHFDMYGFDYKINDRLTAQYHYAE
HHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCCCCEECCCEEEECCEEEEEEEHHH
LEDIYRQHFVGLLANQPLGDGVLKADLRLLKSADSGDAKAGSIDNRALSGMLSYGISGHT
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCE
FSAGWQRMNGDNSMPYLDGSNPYLVNYVQVNDFAAAQERSWQLRYDYDFKAIGINGLSFL
ECCCHHCCCCCCCCCEECCCCCEEEEEEEECCCHHHHCCCEEEEEECCEEEECCCHHHHH
TRYVNGDHIKVPGSDQEGKEWERDSELKYVIQSGTFKDVSLRLRNATYRTNYEKFARDVD
HHHCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEEECCEEECCHHHHHCCCC
ETRLIVSYNFSVL
CCEEEEEECCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339257; 1427017; 10984043; 8012497; 2118530; 8843159; 9636669 [H]