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The map label for this gene is uppP

Identifier: 77458827

GI number: 77458827

Start: 2980320

End: 2981150

Strand: Direct

Name: uppP

Synonym: Pfl01_2602

Alternate gene names: 77458827

Gene position: 2980320-2981150 (Clockwise)

Preceding gene: 77458817

Following gene: 77458828

Centisome position: 46.29

GC content: 60.89

Gene sequence:

>831_bases
ATGGATCTTTGGACGGCCTTGCAGGCACTGATTCTAGGAGTTGTAGAGGGGCTGACGGAGTTTTTGCCCATTTCCAGTAC
CGGACACCAGATCATTGTTGCCGACTTGCTCGATTTCGGAGGCGAGCGGGCCATGGCGTTCAACATCATCATCCAGCTCG
GCGCGATTCTCGCGGTGGTCTGGGAATTCCGCCGCAAGATCCTCGACGTGGTCATTGGCCTGCCGACCCAGCCGAGTGCG
CGACGTTTCACCGCCAACCTGCTGATCGCCTTCCTGCCCGCCGTGGTGCTTGGCGTGATCTTCGCCGACCTGATTCACCA
TTACCTGTTCAACCCGATCACTGTGGCCGCCGCGCTGGTGGTGGGCGGCATCGTGATGTTGTGGGCCGAACAGCGTCAGC
ATGAAGTGCACGCCGAAACGGTTGACGAGATCCGCTGGACGGATGCACTGAAGATCGGTTTCGCCCAGTGTCTGGCGATG
ATCCCCGGCACTTCGCGCTCCGGCTCGACCATCATCGGCGGCCTGTTGTTCGGCCTGTCGCGCAAGACCGCCACCGAGTT
CTCATTCTTCCTGGCGATGCCGACCATGGTCGGTGCGGCGGTGTATTCGGGCTACAAGTATCGCGACCTGTTCGTACCGG
CAGACTTCCCGGTGTTTGCCATCGGTTTCGTCACGGCGTTCATCTTCGCGATGATCGCGGTGCGCGGCCTGCTCAAGTTC
ATCGGCAGCCACAGCTATGCGGCGTTTGCCTGGTACCGGATCGTTTTCGGTCTGGTGATTCTGGCGACCTGGCAGTTCGG
CTGGGTCGACTGGACGGCCGCTCAGCCATGA

Upstream 100 bases:

>100_bases
GCGCGCGGAATCGGTACAGCTTTAACCAGCTACGCTGAACGCAGTGAACGTAAAAAATACTATCGGGGCATGCCTCTGTG
CATCGCTCTCTGGGGGATTG

Downstream 100 bases:

>100_bases
GTGACTCCCGCGCACGTCGCCCGGATCGTGGTCGTTCCGGTGGCAATATCCAGCACTTGAAATTGAAGCTGGCGGTGCTG
CTGATCGTCTGCGCGTTGCC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 1; Undecaprenyl pyrophosphate phosphatase 1

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDLWTALQALILGVVEGLTEFLPISSTGHQIIVADLLDFGGERAMAFNIIIQLGAILAVVWEFRRKILDVVIGLPTQPSA
RRFTANLLIAFLPAVVLGVIFADLIHHYLFNPITVAAALVVGGIVMLWAEQRQHEVHAETVDEIRWTDALKIGFAQCLAM
IPGTSRSGSTIIGGLLFGLSRKTATEFSFFLAMPTMVGAAVYSGYKYRDLFVPADFPVFAIGFVTAFIFAMIAVRGLLKF
IGSHSYAAFAWYRIVFGLVILATWQFGWVDWTAAQP

Sequences:

>Translated_276_residues
MDLWTALQALILGVVEGLTEFLPISSTGHQIIVADLLDFGGERAMAFNIIIQLGAILAVVWEFRRKILDVVIGLPTQPSA
RRFTANLLIAFLPAVVLGVIFADLIHHYLFNPITVAAALVVGGIVMLWAEQRQHEVHAETVDEIRWTDALKIGFAQCLAM
IPGTSRSGSTIIGGLLFGLSRKTATEFSFFLAMPTMVGAAVYSGYKYRDLFVPADFPVFAIGFVTAFIFAMIAVRGLLKF
IGSHSYAAFAWYRIVFGLVILATWQFGWVDWTAAQP
>Mature_276_residues
MDLWTALQALILGVVEGLTEFLPISSTGHQIIVADLLDFGGERAMAFNIIIQLGAILAVVWEFRRKILDVVIGLPTQPSA
RRFTANLLIAFLPAVVLGVIFADLIHHYLFNPITVAAALVVGGIVMLWAEQRQHEVHAETVDEIRWTDALKIGFAQCLAM
IPGTSRSGSTIIGGLLFGLSRKTATEFSFFLAMPTMVGAAVYSGYKYRDLFVPADFPVFAIGFVTAFIFAMIAVRGLLKF
IGSHSYAAFAWYRIVFGLVILATWQFGWVDWTAAQP

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=262, Percent_Identity=48.4732824427481, Blast_Score=216, Evalue=9e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP1_PSEPF (Q3KD12)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_348333.1
- STRING:   Q3KD12
- GeneID:   3714203
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_2602
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   IGHFIGF
- ProtClustDB:   PRK00281
- BioCyc:   PFLU205922:PFL_2602-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30315; Mature: 30315

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x115b9c08)-; HASH(0x11636e6c)-; HASH(0x10ed8a1c)-; HASH(0x10a354a8)-; HASH(0x10660c94)-; HASH(0xd90084c)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCH
>Mature Secondary Structure
MDLWTALQALILGVVEGLTEFLPISSTGHQIIVADLLDFGGERAMAFNIIIQLGAILAVV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
WEFRRKILDVVIGLPTQPSARRFTANLLIAFLPAVVLGVIFADLIHHYLFNPITVAAALV
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
VGGIVMLWAEQRQHEVHAETVDEIRWTDALKIGFAQCLAMIPGTSRSGSTIIGGLLFGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
RKTATEFSFFLAMPTMVGAAVYSGYKYRDLFVPADFPVFAIGFVTAFIFAMIAVRGLLKF
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGSHSYAAFAWYRIVFGLVILATWQFGWVDWTAAQP
HCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA