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The map label for this gene is ybiC [C]

Identifier: 77458792

GI number: 77458792

Start: 2944904

End: 2945935

Strand: Direct

Name: ybiC [C]

Synonym: Pfl01_2567

Alternate gene names: 77458792

Gene position: 2944904-2945935 (Clockwise)

Preceding gene: 77458790

Following gene: 77458794

Centisome position: 45.74

GC content: 63.28

Gene sequence:

>1032_bases
ATGTCTGCGCCACACGATCATGCGATCTCGTCCACGGTGTCCCTGGACGAGCTGACTCAACTGCTGGAAACGATTTTCAC
CCGTCACGGCACCTCGGCCGAAGTCGCCAGAACCCTGGCCACCAATTGCGCCAATGCCGAGCGGGACGGTGCGCACAGTC
ACGGCGTATTCCGGATTCCCGGTTATGTCTCGACGCTCAACAGTGGCTGGGTCAACGGCAAGGCCGTGCCGAAAGTCGAG
GACGTGGCTTCAGGGTTTGTCAGTGTCGATGCCGGCAACGGTTTTGCCCAGCCTGCGCTGGCGGCGGCGCGTCCACTGTT
GGTGGAGAAGGCCCGCAGCGCCGGGATTGCGGTGTTGGCGATCCGAAATTCCCATCACTTTGCCGCACTGTGGCCGGACG
TCGAGCCGTTCGCCGACGAAGGCCTGGTAGCGCTGAGCGTGGTCAACAGCATGACCTGCGTGGTGCCGCACGGCGCCGAC
CGGCCATTGTTCGGCACCAACCCGATCGCCTTCGCCGCGCCACGGGCCGACGGTGCGCCGATCGTGTTCGACCTGGCCAC
CAGCGCCATTGCCCATGGCGATGTGCAGATTGCTGCACGCAAGGGCGAAAAACTGCCGGCAGGCATGGGCGTCGACAGCC
TCGGCCAGCCGACCTGCGACCCTAAGGCGATTCTGGAAGGCGGCGCCTTGCTGCCGTTTGGCGGACACAAGGGGTCAGCG
CTGTCGATGATGGTGGAACTGCTGGCCGCCGCGCTGACTGGCGGCAATTTCTCGTTCGAATTCGACTGGAAAAACCATCC
GGGGGCCAAGACACCGTGGACCGGTCAACTTTTGATCGTGATCGACCCGAGCAAGACCGCCGGACAAAGCTTCGCCGAAC
GCAGTCAGGAACTGGTGCGGCAGATGCACGGGGTAGGGCTCAAGCGTTTGCCGGGTGATCGGCGGCATTTGCAGCGGACC
AAGTCATTGGTCAAAGGGATTGAGCTGGATCAACAGACCCTGTCGCAGCTGCGTGAACTGGCCGGCGAGTAA

Upstream 100 bases:

>100_bases
CGCATCACGGGGTTGACAGGCTACCGGCTGCATGTGGTTAATCCGGTTGCGGGTTGTTCGTTCGCTGTTGTTCCCTCCAA
TAATTACTCTGGAGCTTCAG

Downstream 100 bases:

>100_bases
TTTTTTGCCGGGCATGAAAAAGACGAGCCCGAGGGCTCGCCTTTTTTGTTCGCGCTCAGCGGCGACCGAGCAGCAAGCCG
ACCACCAGACCGAACCCGGC

Product: delta1-piperideine 2-carboxylate reductase

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSAPHDHAISSTVSLDELTQLLETIFTRHGTSAEVARTLATNCANAERDGAHSHGVFRIPGYVSTLNSGWVNGKAVPKVE
DVASGFVSVDAGNGFAQPALAAARPLLVEKARSAGIAVLAIRNSHHFAALWPDVEPFADEGLVALSVVNSMTCVVPHGAD
RPLFGTNPIAFAAPRADGAPIVFDLATSAIAHGDVQIAARKGEKLPAGMGVDSLGQPTCDPKAILEGGALLPFGGHKGSA
LSMMVELLAAALTGGNFSFEFDWKNHPGAKTPWTGQLLIVIDPSKTAGQSFAERSQELVRQMHGVGLKRLPGDRRHLQRT
KSLVKGIELDQQTLSQLRELAGE

Sequences:

>Translated_343_residues
MSAPHDHAISSTVSLDELTQLLETIFTRHGTSAEVARTLATNCANAERDGAHSHGVFRIPGYVSTLNSGWVNGKAVPKVE
DVASGFVSVDAGNGFAQPALAAARPLLVEKARSAGIAVLAIRNSHHFAALWPDVEPFADEGLVALSVVNSMTCVVPHGAD
RPLFGTNPIAFAAPRADGAPIVFDLATSAIAHGDVQIAARKGEKLPAGMGVDSLGQPTCDPKAILEGGALLPFGGHKGSA
LSMMVELLAAALTGGNFSFEFDWKNHPGAKTPWTGQLLIVIDPSKTAGQSFAERSQELVRQMHGVGLKRLPGDRRHLQRT
KSLVKGIELDQQTLSQLRELAGE
>Mature_342_residues
SAPHDHAISSTVSLDELTQLLETIFTRHGTSAEVARTLATNCANAERDGAHSHGVFRIPGYVSTLNSGWVNGKAVPKVED
VASGFVSVDAGNGFAQPALAAARPLLVEKARSAGIAVLAIRNSHHFAALWPDVEPFADEGLVALSVVNSMTCVVPHGADR
PLFGTNPIAFAAPRADGAPIVFDLATSAIAHGDVQIAARKGEKLPAGMGVDSLGQPTCDPKAILEGGALLPFGGHKGSAL
SMMVELLAAALTGGNFSFEFDWKNHPGAKTPWTGQLLIVIDPSKTAGQSFAERSQELVRQMHGVGLKRLPGDRRHLQRTK
SLVKGIELDQQTLSQLRELAGE

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=271, Percent_Identity=34.6863468634686, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786727, Length=324, Percent_Identity=30.2469135802469, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1790000, Length=244, Percent_Identity=27.0491803278689, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17507179, Length=351, Percent_Identity=31.9088319088319, Blast_Score=148, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17536633, Length=360, Percent_Identity=29.4444444444444, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24667904, Length=267, Percent_Identity=31.0861423220974, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24667908, Length=267, Percent_Identity=31.0861423220974, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI45553211, Length=267, Percent_Identity=31.0861423220974, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24667912, Length=267, Percent_Identity=31.0861423220974, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24658010, Length=344, Percent_Identity=26.1627906976744, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24648360, Length=353, Percent_Identity=24.6458923512748, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 36088; Mature: 35957

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPHDHAISSTVSLDELTQLLETIFTRHGTSAEVARTLATNCANAERDGAHSHGVFRIP
CCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEECC
GYVSTLNSGWVNGKAVPKVEDVASGFVSVDAGNGFAQPALAAARPLLVEKARSAGIAVLA
CHHHHHCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
IRNSHHFAALWPDVEPFADEGLVALSVVNSMTCVVPHGADRPLFGTNPIAFAAPRADGAP
EECCCCEEEECCCCCCHHCCCEEEEEHHCCCEEEECCCCCCCCCCCCCCEEECCCCCCCC
IVFDLATSAIAHGDVQIAARKGEKLPAGMGVDSLGQPTCDPKAILEGGALLPFGGHKGSA
EEEEHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEECCCCCCCHH
LSMMVELLAAALTGGNFSFEFDWKNHPGAKTPWTGQLLIVIDPSKTAGQSFAERSQELVR
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
QMHGVGLKRLPGDRRHLQRTKSLVKGIELDQQTLSQLRELAGE
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SAPHDHAISSTVSLDELTQLLETIFTRHGTSAEVARTLATNCANAERDGAHSHGVFRIP
CCCCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEECC
GYVSTLNSGWVNGKAVPKVEDVASGFVSVDAGNGFAQPALAAARPLLVEKARSAGIAVLA
CHHHHHCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
IRNSHHFAALWPDVEPFADEGLVALSVVNSMTCVVPHGADRPLFGTNPIAFAAPRADGAP
EECCCCEEEECCCCCCHHCCCEEEEEHHCCCEEEECCCCCCCCCCCCCCEEECCCCCCCC
IVFDLATSAIAHGDVQIAARKGEKLPAGMGVDSLGQPTCDPKAILEGGALLPFGGHKGSA
EEEEHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEECCCCCCCHH
LSMMVELLAAALTGGNFSFEFDWKNHPGAKTPWTGQLLIVIDPSKTAGQSFAERSQELVR
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
QMHGVGLKRLPGDRRHLQRTKSLVKGIELDQQTLSQLRELAGE
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]