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The map label for this gene is mdtA [H]

Identifier: 77458746

GI number: 77458746

Start: 2878045

End: 2879352

Strand: Direct

Name: mdtA [H]

Synonym: Pfl01_2521

Alternate gene names: 77458746

Gene position: 2878045-2879352 (Clockwise)

Preceding gene: 77458745

Following gene: 77458747

Centisome position: 44.7

GC content: 62.92

Gene sequence:

>1308_bases
ATGGTTAATCAGTCCATGCAATCGTCTTCCCGAAACTCCCGTCGCTGGCTGTTGAGCCTGCTTGTCCTGCTGGTCATTGC
CGGTCTGTGCTGGAAATTCTGGCCGTCCGGTTCGACCCACAAGGAGGGCGGCGAGAAGGCGCAGGCCGGCCACACCGGTC
GTTCGGGGATGATGCGTCCGGGCTTCGGCGGCGCTGCAGGGCCGATTCCGGTGCGCGTGGCGCCGGCAGTCACCGGGGAC
TTCCCGCTGTACTACAAGGCCCTGGGCACGGTGACGGCGCTCAACACCATCAATGTGCGCAGTCGGGTTGGTGGCGAACT
GGTGAAGATTTATTTCGAGGAAGGGCAAATGGTCAAGGCCGGTGACCTGCTGGCGGAGATCGATCCGCGTCCGTACCAGA
ACGCCTTGCTGCAGGCGGAAGGCACCTTGCTGCAGAATCAGGCGCAGTTGAAGAACGCCCAGGTCGATGTCGAGCGCTAT
CGCGGCCTGTACAAGGAAGACAGCATCGCCAAGCAGACGCTGGACACCGCTGAAGCGCTGGTCGGCCAATACCTCGGCAC
CGTGAAAACCAATCAGGCGGCAGTCAACGACGCCAAGCTCAATCTCGAATTCACCAAGATCCGTGCACCGATCGCCGGTC
GCGTCGGCCTGCGTCAGCTCGACGTCGGCAACCTCGTGGCGGCCAACGACACGACCTCCCTGGCGGTGATCACCCAGACC
CAACCGATCAGTGTCGCCTTCACCCTGCCGGAAAACAGTCTGGACACCGTGCTCGCCCGCTATCGCAGCGGCGCCAAACT
GCCGGCCGAAGCCTGGGATCGCGGCGACACCAAACTGCAGGCCACTGGCGTGCTGCAAAGCCTCGACAACCAGATCGACG
TGACCACCGGCACCCTGAAATTCAAGGCGCGCTACGAGAACCGCGATCAGTCGCTGTTCCCCAACCAGTTCGTCAACGTT
CACTTGCTGGCTGACACCTTGAAAGGTGTAGTGCTGGCGCCGTCGGCGGCCATTCAGTTCGGCACCAACGGCACCTTCGT
TTACGCGCTGGACGGCGACAAGAAAGTCACCATCCGCCAGTTGAAGATCGGTGCCAGCGACGGCGAAAACACGGTGGTCA
CCGAAGGCCTGGCCGCCGGCGACCGGGTGGTGCTGGAAGGCACCGACCGTCTGAAGGAAGGCAGTGAAGTGGAAGTGGTC
AACGACAGCAAGGATGTGCCGACCACCCCGACCGAACACCTGCAAGGCAAGTCCGCCGCCACCGCGCCTGACGCCGCCGT
CACCGACAAGGCCAAGAAGGGCGCATGA

Upstream 100 bases:

>100_bases
TTGAAACGTAAGTGGAAGGTAAATTGCCGGTAAAGCTGCTTTGCTAAATCCCCACCAGTGCTTATCGTTCAGCCTCCCGT
AAAAGAAGCCCACGCGCCCA

Downstream 100 bases:

>100_bases
ACATTTCGCGTCTGTTCATCCTCCGTCCGGTCGCCACCACGCTGAGCATGCTGGCCATCGTGTTGGCCGGTCTGATCGCC
TATCGCCTGCTGCCGGTTTC

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MVNQSMQSSSRNSRRWLLSLLVLLVIAGLCWKFWPSGSTHKEGGEKAQAGHTGRSGMMRPGFGGAAGPIPVRVAPAVTGD
FPLYYKALGTVTALNTINVRSRVGGELVKIYFEEGQMVKAGDLLAEIDPRPYQNALLQAEGTLLQNQAQLKNAQVDVERY
RGLYKEDSIAKQTLDTAEALVGQYLGTVKTNQAAVNDAKLNLEFTKIRAPIAGRVGLRQLDVGNLVAANDTTSLAVITQT
QPISVAFTLPENSLDTVLARYRSGAKLPAEAWDRGDTKLQATGVLQSLDNQIDVTTGTLKFKARYENRDQSLFPNQFVNV
HLLADTLKGVVLAPSAAIQFGTNGTFVYALDGDKKVTIRQLKIGASDGENTVVTEGLAAGDRVVLEGTDRLKEGSEVEVV
NDSKDVPTTPTEHLQGKSAATAPDAAVTDKAKKGA

Sequences:

>Translated_435_residues
MVNQSMQSSSRNSRRWLLSLLVLLVIAGLCWKFWPSGSTHKEGGEKAQAGHTGRSGMMRPGFGGAAGPIPVRVAPAVTGD
FPLYYKALGTVTALNTINVRSRVGGELVKIYFEEGQMVKAGDLLAEIDPRPYQNALLQAEGTLLQNQAQLKNAQVDVERY
RGLYKEDSIAKQTLDTAEALVGQYLGTVKTNQAAVNDAKLNLEFTKIRAPIAGRVGLRQLDVGNLVAANDTTSLAVITQT
QPISVAFTLPENSLDTVLARYRSGAKLPAEAWDRGDTKLQATGVLQSLDNQIDVTTGTLKFKARYENRDQSLFPNQFVNV
HLLADTLKGVVLAPSAAIQFGTNGTFVYALDGDKKVTIRQLKIGASDGENTVVTEGLAAGDRVVLEGTDRLKEGSEVEVV
NDSKDVPTTPTEHLQGKSAATAPDAAVTDKAKKGA
>Mature_435_residues
MVNQSMQSSSRNSRRWLLSLLVLLVIAGLCWKFWPSGSTHKEGGEKAQAGHTGRSGMMRPGFGGAAGPIPVRVAPAVTGD
FPLYYKALGTVTALNTINVRSRVGGELVKIYFEEGQMVKAGDLLAEIDPRPYQNALLQAEGTLLQNQAQLKNAQVDVERY
RGLYKEDSIAKQTLDTAEALVGQYLGTVKTNQAAVNDAKLNLEFTKIRAPIAGRVGLRQLDVGNLVAANDTTSLAVITQT
QPISVAFTLPENSLDTVLARYRSGAKLPAEAWDRGDTKLQATGVLQSLDNQIDVTTGTLKFKARYENRDQSLFPNQFVNV
HLLADTLKGVVLAPSAAIQFGTNGTFVYALDGDKKVTIRQLKIGASDGENTVVTEGLAAGDRVVLEGTDRLKEGSEVEVV
NDSKDVPTTPTEHLQGKSAATAPDAAVTDKAKKGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=404, Percent_Identity=45.7920792079208, Blast_Score=345, Evalue=5e-96,
Organism=Escherichia coli, GI1789929, Length=322, Percent_Identity=29.1925465838509, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786668, Length=420, Percent_Identity=30.952380952381, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789665, Length=405, Percent_Identity=27.4074074074074, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87081796, Length=329, Percent_Identity=27.6595744680851, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081951, Length=148, Percent_Identity=33.1081081081081, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46604; Mature: 46604

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNQSMQSSSRNSRRWLLSLLVLLVIAGLCWKFWPSGSTHKEGGEKAQAGHTGRSGMMRP
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFGGAAGPIPVRVAPAVTGDFPLYYKALGTVTALNTINVRSRVGGELVKIYFEEGQMVKA
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHEEEEEHHHHCCCEEEEEEECCCCEEEC
GDLLAEIDPRPYQNALLQAEGTLLQNQAQLKNAQVDVERYRGLYKEDSIAKQTLDTAEAL
CCHHEECCCCHHHHHHHHHCCCHHHHHHHHHCCEEEHHHHCCCCCCHHHHHHHHHHHHHH
VGQYLGTVKTNQAAVNDAKLNLEFTKIRAPIAGRVGLRQLDVGNLVAANDTTSLAVITQT
HHHHHCCCCCCCEECCCEEEEEEEEEEECCCCCCCCCEEECCCCEEEECCCCEEEEEEEC
QPISVAFTLPENSLDTVLARYRSGAKLPAEAWDRGDTKLQATGVLQSLDNQIDVTTGTLK
CCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEEHHHHHHHCCCCEEEEEEEEE
FKARYENRDQSLFPNQFVNVHLLADTLKGVVLAPSAAIQFGTNGTFVYALDGDKKVTIRQ
EEEECCCCCCCCCCCCCEEEEEEEHHHCCEEECCCCEEEECCCCEEEEEECCCCEEEEEE
LKIGASDGENTVVTEGLAAGDRVVLEGTDRLKEGSEVEVVNDSKDVPTTPTEHLQGKSAA
EEECCCCCCCEEEECCCCCCCEEEEECCHHHCCCCEEEEECCCCCCCCCCHHHHCCCCCC
TAPDAAVTDKAKKGA
CCCCCHHCCCCCCCC
>Mature Secondary Structure
MVNQSMQSSSRNSRRWLLSLLVLLVIAGLCWKFWPSGSTHKEGGEKAQAGHTGRSGMMRP
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFGGAAGPIPVRVAPAVTGDFPLYYKALGTVTALNTINVRSRVGGELVKIYFEEGQMVKA
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHEEEEEHHHHCCCEEEEEEECCCCEEEC
GDLLAEIDPRPYQNALLQAEGTLLQNQAQLKNAQVDVERYRGLYKEDSIAKQTLDTAEAL
CCHHEECCCCHHHHHHHHHCCCHHHHHHHHHCCEEEHHHHCCCCCCHHHHHHHHHHHHHH
VGQYLGTVKTNQAAVNDAKLNLEFTKIRAPIAGRVGLRQLDVGNLVAANDTTSLAVITQT
HHHHHCCCCCCCEECCCEEEEEEEEEEECCCCCCCCCEEECCCCEEEECCCCEEEEEEEC
QPISVAFTLPENSLDTVLARYRSGAKLPAEAWDRGDTKLQATGVLQSLDNQIDVTTGTLK
CCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEEHHHHHHHCCCCEEEEEEEEE
FKARYENRDQSLFPNQFVNVHLLADTLKGVVLAPSAAIQFGTNGTFVYALDGDKKVTIRQ
EEEECCCCCCCCCCCCCEEEEEEEHHHCCEEECCCCEEEECCCCEEEEEECCCCEEEEEE
LKIGASDGENTVVTEGLAAGDRVVLEGTDRLKEGSEVEVVNDSKDVPTTPTEHLQGKSAA
EEECCCCCCCEEEECCCCCCCEEEEECCHHHCCCCEEEEECCCCCCCCCCHHHHCCCCCC
TAPDAAVTDKAKKGA
CCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA