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The map label for this gene is dinB

Identifier: 77457422

GI number: 77457422

Start: 1366344

End: 1367405

Strand: Direct

Name: dinB

Synonym: Pfl01_1195

Alternate gene names: 77457422

Gene position: 1366344-1367405 (Clockwise)

Preceding gene: 77457419

Following gene: 77457427

Centisome position: 21.22

GC content: 60.45

Gene sequence:

>1062_bases
ATGACTCAGCGAAAAATCATCCACGTCGACTGTGACTGTTTCTACGCCGCCATCGAGATGCGGGATGACCCGAGCCTCGC
CGGCAAGCCGTTGGCGGTGGGTGGCTCGGCAGACAGGCGCGGAGTGATCGCCACCTGCAACTATGAGGCGCGGGCTTACG
GGGTTCGCTCGGCGATGTCGTCCGGACACGCCCTGAAGCTGTGCCCGGACCTGACTATCGTCAAGCCGCGAATGGACGCC
TATCGCGAGGCGTCGAAGGAAATTCATACGATCTTCAGCGATTACACCGACCTGATCGAGCCTCTTTCCTTGGACGAGGC
CTACCTCGACGTCTCGGACAGCGCGCATTTCGGCGGCAGCGCCACGCGGATCGCCCAGGATATTCGTCGTCGGGTTTCCA
ATCAGTTGCACATCACTGTCTCCGCCGGCGTGGCGCCGAACAAGTTTCTGGCCAAGATCGCCAGCGACTGGAGAAAACCC
AACGGCTTGTTCGTGATCACCCCGGATCAGGTCGAAGAATTCGTCAGTGGCCTGCCGGTGAGCAAGTTGCACGGGGTGGG
CAAGGTCACGGCCGACAAGCTGGGCAAGCTGGGTATCAATGACTGCCTGCAATTGCGCGAGTGGGACAAGCTGGCGCTGG
TGCGGGAATTCGGCAGTTTCGGCGAGCGCTTGTGGAGTCTGGCCCGTGGGATCGATGAGCGGTTGGTGCACAACGACAGT
CGTCGTCAGTCGATCAGCGTCGAAAACACCTACGATGTCGATCTGCCGGATCTGCGCAGCTGCCTCGACAAGCTTCCGGA
ACTACTGGAAACCCTGAAAACCCGCATGGCGCGGATCGACAGCAGCTACCGGCCGGGCAAGCCGTTCGTCAAAGTGAAGT
TTCACGATTTCACCCAGACCACGCTTGAGCAGGCCGGGGCAGGGCGGGATCTGGGCAGTTACCAGTTGATGCTGACCCAG
GCGTTCAATCGCGGTGGTAAGCCGGTGCGGTTGTTGGGGGTGGGTGTGCGGCTCGAAGATTTGCGCGGCGGTTTTGAGCA
GATGGAGTTGTTTGAGCGATAA

Upstream 100 bases:

>100_bases
CCGTTTCCTACAAACTGAAAAGAACATTCTTACCACTGGTGCTATATACAGGTGTCAGTGAGATACTGCCGGTCCGGCTC
GCCATGTTTCCTTTTCTGTC

Downstream 100 bases:

>100_bases
GCGGACAAAAAAATGCCCGAAGCAGGTTCGGGCAATTTTTCAGGGGATTCAGTTCGGCCCCGGATCCGCCACCAGACGCC
CCGCATCCCGGGTCAGGGAC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTQRKIIHVDCDCFYAAIEMRDDPSLAGKPLAVGGSADRRGVIATCNYEARAYGVRSAMSSGHALKLCPDLTIVKPRMDA
YREASKEIHTIFSDYTDLIEPLSLDEAYLDVSDSAHFGGSATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWRKP
NGLFVITPDQVEEFVSGLPVSKLHGVGKVTADKLGKLGINDCLQLREWDKLALVREFGSFGERLWSLARGIDERLVHNDS
RRQSISVENTYDVDLPDLRSCLDKLPELLETLKTRMARIDSSYRPGKPFVKVKFHDFTQTTLEQAGAGRDLGSYQLMLTQ
AFNRGGKPVRLLGVGVRLEDLRGGFEQMELFER

Sequences:

>Translated_353_residues
MTQRKIIHVDCDCFYAAIEMRDDPSLAGKPLAVGGSADRRGVIATCNYEARAYGVRSAMSSGHALKLCPDLTIVKPRMDA
YREASKEIHTIFSDYTDLIEPLSLDEAYLDVSDSAHFGGSATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWRKP
NGLFVITPDQVEEFVSGLPVSKLHGVGKVTADKLGKLGINDCLQLREWDKLALVREFGSFGERLWSLARGIDERLVHNDS
RRQSISVENTYDVDLPDLRSCLDKLPELLETLKTRMARIDSSYRPGKPFVKVKFHDFTQTTLEQAGAGRDLGSYQLMLTQ
AFNRGGKPVRLLGVGVRLEDLRGGFEQMELFER
>Mature_352_residues
TQRKIIHVDCDCFYAAIEMRDDPSLAGKPLAVGGSADRRGVIATCNYEARAYGVRSAMSSGHALKLCPDLTIVKPRMDAY
REASKEIHTIFSDYTDLIEPLSLDEAYLDVSDSAHFGGSATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWRKPN
GLFVITPDQVEEFVSGLPVSKLHGVGKVTADKLGKLGINDCLQLREWDKLALVREFGSFGERLWSLARGIDERLVHNDSR
RQSISVENTYDVDLPDLRSCLDKLPELLETLKTRMARIDSSYRPGKPFVKVKFHDFTQTTLEQAGAGRDLGSYQLMLTQA
FNRGGKPVRLLGVGVRLEDLRGGFEQMELFER

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7706681, Length=356, Percent_Identity=28.9325842696629, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI84043967, Length=355, Percent_Identity=29.0140845070423, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI154350220, Length=314, Percent_Identity=30.5732484076433, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=49.5327102803738, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI5729982, Length=122, Percent_Identity=40.1639344262295, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1786425, Length=339, Percent_Identity=51.0324483775811, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI1787432, Length=230, Percent_Identity=27.3913043478261, Blast_Score=78, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=395, Percent_Identity=29.3670886075949, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17537959, Length=240, Percent_Identity=28.3333333333333, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI115534089, Length=124, Percent_Identity=37.9032258064516, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193205702, Length=230, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=211, Percent_Identity=27.9620853080569, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19923006, Length=327, Percent_Identity=27.82874617737, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21355641, Length=285, Percent_Identity=32.6315789473684, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24644984, Length=285, Percent_Identity=32.6315789473684, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24668444, Length=121, Percent_Identity=35.5371900826446, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_PSEPF (Q3KH18)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_346927.1
- HSSP:   Q9UNA4
- ProteinModelPortal:   Q3KH18
- SMR:   Q3KH18
- STRING:   Q3KH18
- GeneID:   3716967
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_1195
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   QAMARQE
- ProtClustDB:   PRK02406
- BioCyc:   PFLU205922:PFL_1195-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 39375; Mature: 39244

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRKIIHVDCDCFYAAIEMRDDPSLAGKPLAVGGSADRRGVIATCNYEARAYGVRSAMS
CCCCEEEEEECCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHC
SGHALKLCPDLTIVKPRMDAYREASKEIHTIFSDYTDLIEPLSLDEAYLDVSDSAHFGGS
CCCEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCH
ATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWRKPNGLFVITPDQVEEFVSGLPV
HHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCCH
SKLHGVGKVTADKLGKLGINDCLQLREWDKLALVREFGSFGERLWSLARGIDERLVHNDS
HHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RRQSISVENTYDVDLPDLRSCLDKLPELLETLKTRMARIDSSYRPGKPFVKVKFHDFTQT
HHCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHH
TLEQAGAGRDLGSYQLMLTQAFNRGGKPVRLLGVGVRLEDLRGGFEQMELFER
HHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECEEEHHHHCCHHHHHHHCC
>Mature Secondary Structure 
TQRKIIHVDCDCFYAAIEMRDDPSLAGKPLAVGGSADRRGVIATCNYEARAYGVRSAMS
CCCEEEEEECCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHC
SGHALKLCPDLTIVKPRMDAYREASKEIHTIFSDYTDLIEPLSLDEAYLDVSDSAHFGGS
CCCEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCH
ATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWRKPNGLFVITPDQVEEFVSGLPV
HHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCCH
SKLHGVGKVTADKLGKLGINDCLQLREWDKLALVREFGSFGERLWSLARGIDERLVHNDS
HHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RRQSISVENTYDVDLPDLRSCLDKLPELLETLKTRMARIDSSYRPGKPFVKVKFHDFTQT
HHCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHH
TLEQAGAGRDLGSYQLMLTQAFNRGGKPVRLLGVGVRLEDLRGGFEQMELFER
HHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECEEEHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA