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The map label for this gene is mdtA [H]

Identifier: 77457306

GI number: 77457306

Start: 1246564

End: 1247664

Strand: Direct

Name: mdtA [H]

Synonym: Pfl01_1079

Alternate gene names: 77457306

Gene position: 1246564-1247664 (Clockwise)

Preceding gene: 77457304

Following gene: 77457307

Centisome position: 19.36

GC content: 64.12

Gene sequence:

>1101_bases
ATGTTCCGCCATGCGTTGTCCTTTGCGGTGCCAGTCAGTCTGGCGTTTTTGTTGTCGGCGTGTGGCAAGGAAGAGGTGAC
GCCAGTCAGCGTGCGACCGGCCATGGTGGTGCAGCCAGAGCCTTCGGCGCAGGCGATGGAGAGTTATCCGGGCGAGGTTC
GCGCCCGCTACGAACCGGATCTGGCGTTCCGCATCGGCGGCAAAGTCAGCCGACGACTGGTCGATGAAGGCCAGCGCGTG
AAGGCCGATCAACCACTCGCCGAACTCGATCCGCAGGATGTACGCCTGCAACTGGAAGCCACCCGGGCCCAGGTTGCGGC
CGCCGAAGCCAACCTGAACCTGGTGCGTGCCGAACGTGACCGCTACAAGACCCTGATGGAACGGCAGATGGTCAGCCGCT
CGGCCTACGACAATGCCGAGAACCTCTATCGCTCCGGCGAAGCCCGCCTCAAACAGATCAAAGCCGAATTCAACGTCTCG
ACCAATCAGGCCAGTTACGCCGTGTTGCGTGCGCCCCAGGATGGCGTGGTGGCCAAGCGTTCGGTGGAAGTCGGGCAGGT
GGTTGCCGCTGGGCAGACCGTTTTCACCCTCGCCACTGACGGCGAACGGGAAGTGCTGATCAGCCTGCCGGAGCAGAGCT
TCGGTCGCTTCAAGGTCGGCCAGCCGGTGTCGGTAGAGCTGTGGACACAACAGAACCAGCGCTTCGCCGGGCAGATCCGC
GAGCTGTCGCCAGCCGCCGATCCGAAATCCCGCACCTTTGCCGCACGCATTTCATTCACCTCCGGCAAAGTCCCTGCGGA
ACTGGGTCAGAGCGCCCGGGTCTTCGTGCAGACCGCCGATGTCATCCCGCTGTCTGTGCCGCTCTCGGCGCTGACGGCCG
AGAACGGCGCGACCTACGTCTGGGTCGTCAGCGCCAACAACACCCTGAAAAAGACCCCGGTGCGCGTCGGCCCGTTCGGT
GAGAAAACCGTGCCGGTGCTCGAAGGCCTGAACGCCAGCGACTGGGTGGTCGCCGCTGGCGTCCATGTGCTGCTGGAAGG
GCAGCAGGTGCGTCCGGTGGATCGCTCCAACCGCGTGGTCAATCTGGCGGACAAGGAGTAA

Upstream 100 bases:

>100_bases
CGACATTCTTCGCTTTTAATACTGGACTGGTGAGTTTGCTATTAATAACATACCGGCCAGTATAATTATTCCAAGCCTCC
TTAGCGAAAGGTCCTTCACC

Downstream 100 bases:

>100_bases
TCCCCGATGGGTTTCAATCTTTCCGCCTGGGCGCTGCGCAATCGCCAGATCGTACTGTTCCTGATGCTTTTGCTGGCGAT
CGTCGGCGCCTTGTCCTACA

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MFRHALSFAVPVSLAFLLSACGKEEVTPVSVRPAMVVQPEPSAQAMESYPGEVRARYEPDLAFRIGGKVSRRLVDEGQRV
KADQPLAELDPQDVRLQLEATRAQVAAAEANLNLVRAERDRYKTLMERQMVSRSAYDNAENLYRSGEARLKQIKAEFNVS
TNQASYAVLRAPQDGVVAKRSVEVGQVVAAGQTVFTLATDGEREVLISLPEQSFGRFKVGQPVSVELWTQQNQRFAGQIR
ELSPAADPKSRTFAARISFTSGKVPAELGQSARVFVQTADVIPLSVPLSALTAENGATYVWVVSANNTLKKTPVRVGPFG
EKTVPVLEGLNASDWVVAAGVHVLLEGQQVRPVDRSNRVVNLADKE

Sequences:

>Translated_366_residues
MFRHALSFAVPVSLAFLLSACGKEEVTPVSVRPAMVVQPEPSAQAMESYPGEVRARYEPDLAFRIGGKVSRRLVDEGQRV
KADQPLAELDPQDVRLQLEATRAQVAAAEANLNLVRAERDRYKTLMERQMVSRSAYDNAENLYRSGEARLKQIKAEFNVS
TNQASYAVLRAPQDGVVAKRSVEVGQVVAAGQTVFTLATDGEREVLISLPEQSFGRFKVGQPVSVELWTQQNQRFAGQIR
ELSPAADPKSRTFAARISFTSGKVPAELGQSARVFVQTADVIPLSVPLSALTAENGATYVWVVSANNTLKKTPVRVGPFG
EKTVPVLEGLNASDWVVAAGVHVLLEGQQVRPVDRSNRVVNLADKE
>Mature_366_residues
MFRHALSFAVPVSLAFLLSACGKEEVTPVSVRPAMVVQPEPSAQAMESYPGEVRARYEPDLAFRIGGKVSRRLVDEGQRV
KADQPLAELDPQDVRLQLEATRAQVAAAEANLNLVRAERDRYKTLMERQMVSRSAYDNAENLYRSGEARLKQIKAEFNVS
TNQASYAVLRAPQDGVVAKRSVEVGQVVAAGQTVFTLATDGEREVLISLPEQSFGRFKVGQPVSVELWTQQNQRFAGQIR
ELSPAADPKSRTFAARISFTSGKVPAELGQSARVFVQTADVIPLSVPLSALTAENGATYVWVVSANNTLKKTPVRVGPFG
EKTVPVLEGLNASDWVVAAGVHVLLEGQQVRPVDRSNRVVNLADKE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=302, Percent_Identity=27.8145695364238, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081796, Length=333, Percent_Identity=27.9279279279279, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789929, Length=367, Percent_Identity=22.3433242506812, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39937; Mature: 39937

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRHALSFAVPVSLAFLLSACGKEEVTPVSVRPAMVVQPEPSAQAMESYPGEVRARYEPD
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEECCCCCHHHHHCCCCCEEEEECCC
LAFRIGGKVSRRLVDEGQRVKADQPLAELDPQDVRLQLEATRAQVAAAEANLNLVRAERD
EEEEECCHHHHHHHCCCCEECCCCCHHHCCCCCEEEEEEEHHHHHHHHHCCCEEEEHHHH
RYKTLMERQMVSRSAYDNAENLYRSGEARLKQIKAEFNVSTNQASYAVLRAPQDGVVAKR
HHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEC
SVEVGQVVAAGQTVFTLATDGEREVLISLPEQSFGRFKVGQPVSVELWTQQNQRFAGQIR
CCCHHHEEECCCEEEEEECCCCCEEEEECCCCCCCCEECCCCCEEEEECCCCHHHHHHHH
ELSPAADPKSRTFAARISFTSGKVPAELGQSARVFVQTADVIPLSVPLSALTAENGATYV
HCCCCCCCCCCEEEEEEEECCCCCCHHHCCCEEEEEEECCEEEEECCHHHEECCCCCEEE
WVVSANNTLKKTPVRVGPFGEKTVPVLEGLNASDWVVAAGVHVLLEGQQVRPVDRSNRVV
EEEECCCCEECCCEEECCCCCCCHHHHCCCCCCCEEEECCEEEEEECCCCCCCCCCCCEE
NLADKE
EECCCC
>Mature Secondary Structure
MFRHALSFAVPVSLAFLLSACGKEEVTPVSVRPAMVVQPEPSAQAMESYPGEVRARYEPD
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEECCCCCHHHHHCCCCCEEEEECCC
LAFRIGGKVSRRLVDEGQRVKADQPLAELDPQDVRLQLEATRAQVAAAEANLNLVRAERD
EEEEECCHHHHHHHCCCCEECCCCCHHHCCCCCEEEEEEEHHHHHHHHHCCCEEEEHHHH
RYKTLMERQMVSRSAYDNAENLYRSGEARLKQIKAEFNVSTNQASYAVLRAPQDGVVAKR
HHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEC
SVEVGQVVAAGQTVFTLATDGEREVLISLPEQSFGRFKVGQPVSVELWTQQNQRFAGQIR
CCCHHHEEECCCEEEEEECCCCCEEEEECCCCCCCCEECCCCCEEEEECCCCHHHHHHHH
ELSPAADPKSRTFAARISFTSGKVPAELGQSARVFVQTADVIPLSVPLSALTAENGATYV
HCCCCCCCCCCEEEEEEEECCCCCCHHHCCCEEEEEEECCEEEEECCHHHEECCCCCEEE
WVVSANNTLKKTPVRVGPFGEKTVPVLEGLNASDWVVAAGVHVLLEGQQVRPVDRSNRVV
EEEECCCCEECCCEEECCCCCCCHHHHCCCCCCCEEEECCEEEEEECCCCCCCCCCCCEE
NLADKE
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA