Click here to switch to the map view.

The map label for this gene is hupB [H]

Identifier: 77457211

GI number: 77457211

Start: 1143800

End: 1144081

Strand: Direct

Name: hupB [H]

Synonym: Pfl01_0984

Alternate gene names: 77457211

Gene position: 1143800-1144081 (Clockwise)

Preceding gene: 77457208

Following gene: 77457217

Centisome position: 17.77

GC content: 56.74

Gene sequence:

>282_bases
ATGGCTCTTACTAAAGACCAACTGATCGCCGACATCGCTGAAGCTATCGACGCGCCGAAAACCACCGCGCGTAACGCTCT
GGACCAACTGGGCCAAATCGTTGCCGATCAGCTGGAAAACGGCGGCGAAATCACCTTGCCAGGTATCGGCAAGCTGAAAG
TGACCGAGCGTCCTGCCCGCACTGGCCGTAACCCATCGACTGGCGCTGCCATCGAAATCCCTGCCAAGAAAGTGATCAAG
CTGGTTGTGGCCAAAGGCCTGACCGACGCTGTGAACAAGTAA

Upstream 100 bases:

>100_bases
GTCGTGGTTATCGCCGAGGGTGCCAGATCCAGAAGATCGGGCTCGATGGCTGACACTGCACTCTGCAATCCATATGAATT
TGATAGGGAAGGAACACTAC

Downstream 100 bases:

>100_bases
GACGCAGCGATAAAAAAACCGTGCACCGGAGCGATCCGGGCACGGTTTTTTTGTGCCTGCTGTTTGTGTTTCAGCAGTAG
CGGCGGCTGCTTGCGGTCAA

Product: histone-like DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 93; Mature: 92

Protein sequence:

>93_residues
MALTKDQLIADIAEAIDAPKTTARNALDQLGQIVADQLENGGEITLPGIGKLKVTERPARTGRNPSTGAAIEIPAKKVIK
LVVAKGLTDAVNK

Sequences:

>Translated_93_residues
MALTKDQLIADIAEAIDAPKTTARNALDQLGQIVADQLENGGEITLPGIGKLKVTERPARTGRNPSTGAAIEIPAKKVIK
LVVAKGLTDAVNK
>Mature_92_residues
ALTKDQLIADIAEAIDAPKTTARNALDQLGQIVADQLENGGEITLPGIGKLKVTERPARTGRNPSTGAAIEIPAKKVIKL
VVAKGLTDAVNK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=45.5555555555556, Blast_Score=69, Evalue=5e-14,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=42.6966292134831, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9697; Mature: 9566

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTKDQLIADIAEAIDAPKTTARNALDQLGQIVADQLENGGEITLPGIGKLKVTERPAR
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCHHH
TGRNPSTGAAIEIPAKKVIKLVVAKGLTDAVNK
CCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALTKDQLIADIAEAIDAPKTTARNALDQLGQIVADQLENGGEITLPGIGKLKVTERPAR
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCHHH
TGRNPSTGAAIEIPAKKVIKLVVAKGLTDAVNK
CCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6299736; 10762258; 11481430; 7049166 [H]