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The map label for this gene is moaC [H]

Identifier: 77457191

GI number: 77457191

Start: 1125634

End: 1126107

Strand: Direct

Name: moaC [H]

Synonym: Pfl01_0964

Alternate gene names: 77457191

Gene position: 1125634-1126107 (Clockwise)

Preceding gene: 77457190

Following gene: 77457192

Centisome position: 17.48

GC content: 63.29

Gene sequence:

>474_bases
GTGCTGACTCATCTCGATTCCCAAGGTCGCGCCAACATGGTCGACGTCACCGAAAAAGCCGTGACGTTCCGTGAAGCGAC
GGCCCAAGCGCTGGTGCGCATGCTGCCCGACACCCTGCAGATGATCGTCAGCGGCGGCCATCCCAAGGGCGACGTGTTCG
CCGTGGCGCGCATTGCCGGCATTCAGGCGGCGAAAAAAACCAGTGACCTGATTCCCCTGTGCCATCCGTTGATGCTGACC
GGCGTCAAGGTCGAGCTCAGTGCCGAAGGTGACGACGCGGTGCGCATCGTGGCTCGCTGCAAATTGTCCGGGCAGACCGG
TGTGGAGATGGAAGCGCTGACCGCCGCCAGCGTCGCCGCGCTGACGATCTACGACATGTGCAAGGCCGTGGATCGCGGCA
TGACCATCGAAAGTGTGCGCCTGCTGGAGAAAGTCGGCGGCAAGAGCGGGCATTTCCAGGCGGAGCAGCCATGA

Upstream 100 bases:

>100_bases
CGTCAAACCGAACCGGGCGACTGCAAAGTCGCCCGGTTTTTTATGTGCGCAATTCTGACCCCCAGGTTTACAATCGGTGC
TCCTGATCAGGAGTAATCCC

Downstream 100 bases:

>100_bases
ACCTGACCGTGAAGTTTTTTGCCCGTTACCGCGAAGCGCTGGGCGTGGATTCGGTGACGGTCGAGGGTGATTTCGCCACC
GTCGATGATGTTCGTGCGTT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MLTHLDSQGRANMVDVTEKAVTFREATAQALVRMLPDTLQMIVSGGHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLT
GVKVELSAEGDDAVRIVARCKLSGQTGVEMEALTAASVAALTIYDMCKAVDRGMTIESVRLLEKVGGKSGHFQAEQP

Sequences:

>Translated_157_residues
MLTHLDSQGRANMVDVTEKAVTFREATAQALVRMLPDTLQMIVSGGHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLT
GVKVELSAEGDDAVRIVARCKLSGQTGVEMEALTAASVAALTIYDMCKAVDRGMTIESVRLLEKVGGKSGHFQAEQP
>Mature_157_residues
MLTHLDSQGRANMVDVTEKAVTFREATAQALVRMLPDTLQMIVSGGHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLT
GVKVELSAEGDDAVRIVARCKLSGQTGVEMEALTAASVAALTIYDMCKAVDRGMTIESVRLLEKVGGKSGHFQAEQP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=66.4516129032258, Blast_Score=198, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI32566331, Length=152, Percent_Identity=40.1315789473684, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28574490, Length=157, Percent_Identity=54.140127388535, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28574492, Length=146, Percent_Identity=53.4246575342466, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16676; Mature: 16676

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTHLDSQGRANMVDVTEKAVTFREATAQALVRMLPDTLQMIVSGGHPKGDVFAVARIAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IQAAKKTSDLIPLCHPLMLTGVKVELSAEGDDAVRIVARCKLSGQTGVEMEALTAASVAA
HHHHHHCCCCHHHHHHHHHCCEEEEEECCCCHHEEHEEHHCCCCCCCCCHHHHHHHHHHH
LTIYDMCKAVDRGMTIESVRLLEKVGGKSGHFQAEQP
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLTHLDSQGRANMVDVTEKAVTFREATAQALVRMLPDTLQMIVSGGHPKGDVFAVARIAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IQAAKKTSDLIPLCHPLMLTGVKVELSAEGDDAVRIVARCKLSGQTGVEMEALTAASVAA
HHHHHHCCCCHHHHHHHHHCCEEEEEECCCCHHEEHEEHHCCCCCCCCCHHHHHHHHHHH
LTIYDMCKAVDRGMTIESVRLLEKVGGKSGHFQAEQP
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA