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The map label for this gene is hlyB [H]

Identifier: 77457016

GI number: 77457016

Start: 926146

End: 928176

Strand: Direct

Name: hlyB [H]

Synonym: Pfl01_0789

Alternate gene names: 77457016

Gene position: 926146-928176 (Clockwise)

Preceding gene: 77457015

Following gene: 77457017

Centisome position: 14.38

GC content: 60.81

Gene sequence:

>2031_bases
GTGAAGAGCTTGCTCTATCCCGCCGTCTCGCTGATGAACCGCTTGAGCTTCGGCATGAAGTTCAGCCTGATCAGCGTGCT
GTTCCTGGTGCCGATGCTGGTGACCAATTTCTATCTGGTGCGCGATTCCTATCGCGAATTCCAGGGCACCCGGGTGGAGC
TGCAGAGCCTCGACCTGCTGGGCAGCAGCCTGACCCTGCGCCGGGATCTGGAAACCCTCAACAATCTGGTGCAGATCAAC
GTCACCCTCGGCCAGTCCGGAAAGGCCGGCAATGTCGAGGCGCAAATCGCCAGCCTTGAGCAAAACGTCCTGGCGCGCCT
GCAAGGGCTGACGCCCATGACCGAGGATCCTGAGCAGATCAAGTTTTTCGAGGCCAAGCGCGATGAAATGATCGCTGCGT
TCAAGAACCAACAAGCGGAAAACTCCCTGCAAAGCAAAAGTGCGCTGATCGGCAAACTGCTGGGCAATGCGCAGGTTTTC
AGCCAGATCGTGGCCAGTCAGGCCGGATTGAGTCGCGACAACCAGAGCGACATTCGCCAGCTCACCGAGCTGATCACCGC
GAATACGCCGGCCGTCACCCAGGCCTTGGGCGAAGGTCGGGCGATGGGTTCGTATTCATTGGGCCAGGGCTTTCTCAACA
GTTCGTCGAGCACCCGTTTCGACGAGCTGCTGGTGCAGATTGAAAAACTTCAGGCCGAATATGGCCTGAAATTGCAGGAC
GCGCTGGGCTCCAGCAAAGCCGCCCGTGACTCCCTGAGCGCACTGGCGGATGCCAGCAAGGCGTCGTTGAAACAGGCCGG
CACACTGATCGAAGAACAAGTGGTGATGGCCGAAACGCTCGACGCTCCATGGCAGGGGTTTTATGACCAGGTCACCGGGC
TGATGGACCAGACCTATCAGCTCGACGACGCCACTCTGAAATTCCTCGACACCCAATTGCAGCAGCGCCTGGGGCAAAAC
CGCACGCACATGGTGCTGCAAGCCGTGGCGTTGTCGGTAGTGTTCGTGCTGATTTTCTATCTCTATGGCGGCTTCTACGC
GTCGACCCGCGCGACCCTGAAAAACCTCGGCGCCATGATGGATAAGGTCGCGGCGGGCGACATGACGGTGAATTTCCGCG
CCAACAGCCGCGATGAACTCGGCGAGTTGGGCGAAGTGTTCAATGGTACGGTGCGGAAAATCCACGACCTGATCGAACGG
GTCGGCCATACCGTTGGCGAGGTCGAGCGACAGGCGGGGCAAGTGGAAAACGTCTCGGCACAAAGCAATCAGGCAGTCGC
CGGGCAGCGCACGCAGATCGAACAAGTGGCCACCGCGATGAACCAGATGTCGGCGACATCGCTGGAGGTGGCACGCAGTG
CAGCGGCAGCGGTCAGCAGCGCCCACAGCGTGAACGACGAAACCATCAGTGGTCGCGGGCTGGTGGAATCGCAGCAGGGC
AGCATCGCGGCACTGGCGAGCGAAATCGATCAGTCGGTGCTGGTGATCAACCAGTTGGCCAGCGACAGTCAGTCGATCAG
CCGCGTTCTGGAAGTGATCAAGAGCATCGCCGAACAGACCAATCTGCTGGCGCTCAACGCCGCGATCGAGGCCGCGCGGG
CCGGTGAGCAGGGCCGCGGTTTTGCCGTGGTCGCTGACGAAGTCCGGACGCTGGCCAAACGCACTCAGCAATCGACCGAA
GAAATCGAACAGATGATCGCCAAACTCCACGGCGGCGTCGGCGCGGCAGTAAAGGCCATGGGCGTCAGCCATCAGATGGC
CAACGGCACGGTGGGACAGTCGGAAAAAGTCCAGCAGGCGCTGGAAAACATCCTCGGCGCTGTGGGCATGATCGTCGACC
AGAACCAGCAGATTGCCGCCGCCGTCGAGCAGCAGACCGCCGTGGCCCACGACATCGACCAGAACATCGTCGAGATCAAC
CGTGCTGGCGAGCGCACCGCAGAAGGCGCGCATCAGACCGAAGATGCCAGCCGCGCGTTGTCGGCGCAGGTGGTCGAGTT
GAAGCAGTTGATCAGCGCGTTCCGGGTTTGA

Upstream 100 bases:

>100_bases
CCTTCGATTTGAGCTATACAGAGATGGCGCCCGATAGTGGCTATCTGCTGTCGCCCCGCGCCTGCCAATAAAAACAAGAA
AAAACCAAGGGAGACTTCCA

Downstream 100 bases:

>100_bases
ATCGACCTGCCTCCTCTGAGGCAGGTTTTTCGGAATGGTTTGTAGTACTTTTTGGCTTACATCTGTAAGCAAAATCCTGT
TTTCCTCCGGTAGCTGGTTT

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MKSLLYPAVSLMNRLSFGMKFSLISVLFLVPMLVTNFYLVRDSYREFQGTRVELQSLDLLGSSLTLRRDLETLNNLVQIN
VTLGQSGKAGNVEAQIASLEQNVLARLQGLTPMTEDPEQIKFFEAKRDEMIAAFKNQQAENSLQSKSALIGKLLGNAQVF
SQIVASQAGLSRDNQSDIRQLTELITANTPAVTQALGEGRAMGSYSLGQGFLNSSSSTRFDELLVQIEKLQAEYGLKLQD
ALGSSKAARDSLSALADASKASLKQAGTLIEEQVVMAETLDAPWQGFYDQVTGLMDQTYQLDDATLKFLDTQLQQRLGQN
RTHMVLQAVALSVVFVLIFYLYGGFYASTRATLKNLGAMMDKVAAGDMTVNFRANSRDELGELGEVFNGTVRKIHDLIER
VGHTVGEVERQAGQVENVSAQSNQAVAGQRTQIEQVATAMNQMSATSLEVARSAAAAVSSAHSVNDETISGRGLVESQQG
SIAALASEIDQSVLVINQLASDSQSISRVLEVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAKRTQQSTE
EIEQMIAKLHGGVGAAVKAMGVSHQMANGTVGQSEKVQQALENILGAVGMIVDQNQQIAAAVEQQTAVAHDIDQNIVEIN
RAGERTAEGAHQTEDASRALSAQVVELKQLISAFRV

Sequences:

>Translated_676_residues
MKSLLYPAVSLMNRLSFGMKFSLISVLFLVPMLVTNFYLVRDSYREFQGTRVELQSLDLLGSSLTLRRDLETLNNLVQIN
VTLGQSGKAGNVEAQIASLEQNVLARLQGLTPMTEDPEQIKFFEAKRDEMIAAFKNQQAENSLQSKSALIGKLLGNAQVF
SQIVASQAGLSRDNQSDIRQLTELITANTPAVTQALGEGRAMGSYSLGQGFLNSSSSTRFDELLVQIEKLQAEYGLKLQD
ALGSSKAARDSLSALADASKASLKQAGTLIEEQVVMAETLDAPWQGFYDQVTGLMDQTYQLDDATLKFLDTQLQQRLGQN
RTHMVLQAVALSVVFVLIFYLYGGFYASTRATLKNLGAMMDKVAAGDMTVNFRANSRDELGELGEVFNGTVRKIHDLIER
VGHTVGEVERQAGQVENVSAQSNQAVAGQRTQIEQVATAMNQMSATSLEVARSAAAAVSSAHSVNDETISGRGLVESQQG
SIAALASEIDQSVLVINQLASDSQSISRVLEVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAKRTQQSTE
EIEQMIAKLHGGVGAAVKAMGVSHQMANGTVGQSEKVQQALENILGAVGMIVDQNQQIAAAVEQQTAVAHDIDQNIVEIN
RAGERTAEGAHQTEDASRALSAQVVELKQLISAFRV
>Mature_676_residues
MKSLLYPAVSLMNRLSFGMKFSLISVLFLVPMLVTNFYLVRDSYREFQGTRVELQSLDLLGSSLTLRRDLETLNNLVQIN
VTLGQSGKAGNVEAQIASLEQNVLARLQGLTPMTEDPEQIKFFEAKRDEMIAAFKNQQAENSLQSKSALIGKLLGNAQVF
SQIVASQAGLSRDNQSDIRQLTELITANTPAVTQALGEGRAMGSYSLGQGFLNSSSSTRFDELLVQIEKLQAEYGLKLQD
ALGSSKAARDSLSALADASKASLKQAGTLIEEQVVMAETLDAPWQGFYDQVTGLMDQTYQLDDATLKFLDTQLQQRLGQN
RTHMVLQAVALSVVFVLIFYLYGGFYASTRATLKNLGAMMDKVAAGDMTVNFRANSRDELGELGEVFNGTVRKIHDLIER
VGHTVGEVERQAGQVENVSAQSNQAVAGQRTQIEQVATAMNQMSATSLEVARSAAAAVSSAHSVNDETISGRGLVESQQG
SIAALASEIDQSVLVINQLASDSQSISRVLEVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAKRTQQSTE
EIEQMIAKLHGGVGAAVKAMGVSHQMANGTVGQSEKVQQALENILGAVGMIVDQNQQIAAAVEQQTAVAHDIDQNIVEIN
RAGERTAEGAHQTEDASRALSAQVVELKQLISAFRV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=404, Percent_Identity=29.9504950495049, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI2367378, Length=416, Percent_Identity=29.3269230769231, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788195, Length=340, Percent_Identity=31.4705882352941, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788194, Length=328, Percent_Identity=28.9634146341463, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789453, Length=218, Percent_Identity=30.2752293577982, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72827; Mature: 72827

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLLYPAVSLMNRLSFGMKFSLISVLFLVPMLVTNFYLVRDSYREFQGTRVELQSLDLL
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GSSLTLRRDLETLNNLVQINVTLGQSGKAGNVEAQIASLEQNVLARLQGLTPMTEDPEQI
CCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KFFEAKRDEMIAAFKNQQAENSLQSKSALIGKLLGNAQVFSQIVASQAGLSRDNQSDIRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHH
LTELITANTPAVTQALGEGRAMGSYSLGQGFLNSSSSTRFDELLVQIEKLQAEYGLKLQD
HHHHHHCCCHHHHHHHHCCCCCCCCHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHH
ALGSSKAARDSLSALADASKASLKQAGTLIEEQVVMAETLDAPWQGFYDQVTGLMDQTYQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
LDDATLKFLDTQLQQRLGQNRTHMVLQAVALSVVFVLIFYLYGGFYASTRATLKNLGAMM
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DKVAAGDMTVNFRANSRDELGELGEVFNGTVRKIHDLIERVGHTVGEVERQAGQVENVSA
HHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QSNQAVAGQRTQIEQVATAMNQMSATSLEVARSAAAAVSSAHSVNDETISGRGLVESQQG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SIAALASEIDQSVLVINQLASDSQSISRVLEVIKSIAEQTNLLALNAAIEAARAGEQGRG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCC
FAVVADEVRTLAKRTQQSTEEIEQMIAKLHGGVGAAVKAMGVSHQMANGTVGQSEKVQQA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHCCCCCCCHHHHHHH
LENILGAVGMIVDQNQQIAAAVEQQTAVAHDIDQNIVEINRAGERTAEGAHQTEDASRAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHH
SAQVVELKQLISAFRV
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSLLYPAVSLMNRLSFGMKFSLISVLFLVPMLVTNFYLVRDSYREFQGTRVELQSLDLL
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GSSLTLRRDLETLNNLVQINVTLGQSGKAGNVEAQIASLEQNVLARLQGLTPMTEDPEQI
CCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KFFEAKRDEMIAAFKNQQAENSLQSKSALIGKLLGNAQVFSQIVASQAGLSRDNQSDIRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHH
LTELITANTPAVTQALGEGRAMGSYSLGQGFLNSSSSTRFDELLVQIEKLQAEYGLKLQD
HHHHHHCCCHHHHHHHHCCCCCCCCHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHH
ALGSSKAARDSLSALADASKASLKQAGTLIEEQVVMAETLDAPWQGFYDQVTGLMDQTYQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
LDDATLKFLDTQLQQRLGQNRTHMVLQAVALSVVFVLIFYLYGGFYASTRATLKNLGAMM
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DKVAAGDMTVNFRANSRDELGELGEVFNGTVRKIHDLIERVGHTVGEVERQAGQVENVSA
HHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QSNQAVAGQRTQIEQVATAMNQMSATSLEVARSAAAAVSSAHSVNDETISGRGLVESQQG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SIAALASEIDQSVLVINQLASDSQSISRVLEVIKSIAEQTNLLALNAAIEAARAGEQGRG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCC
FAVVADEVRTLAKRTQQSTEEIEQMIAKLHGGVGAAVKAMGVSHQMANGTVGQSEKVQQA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHCCCCCCCHHHHHHH
LENILGAVGMIVDQNQQIAAAVEQQTAVAHDIDQNIVEINRAGERTAEGAHQTEDASRAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHH
SAQVVELKQLISAFRV
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]