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The map label for this gene is dinF [H]

Identifier: 77456858

GI number: 77456858

Start: 741694

End: 743043

Strand: Reverse

Name: dinF [H]

Synonym: Pfl01_0630

Alternate gene names: 77456858

Gene position: 743043-741694 (Counterclockwise)

Preceding gene: 77456859

Following gene: 77456851

Centisome position: 11.54

GC content: 66.81

Gene sequence:

>1350_bases
ATGTCCAACCTGATCACCGACTGGCGCGACCGCCCGACCCATCGCCGGGTCTGGGCCCTCGCCGCCCCCATGATCCTCTC
CAACATTTCCGTGCCACTGGTGGCGCTGGTCGACAGCACCGTCATCGGCCACCTGCCCCATGCCCATCAACTGGGCGCGG
TGGCCGTGGGTGCCAGCCTGTACACCTTTCTGGCCTGGGCCATGGGATTCCTGCGCATGGGCACCACCGGCTTCGCCGCC
CAGGCTGCGGGTCGCAGCGATGGTGCAGCCTTGCGGCAGATTCTGCTTCAGGGCCTGCTGCTGGCGATGGGGCTGGCGCT
GCTGCTTGGAACGCTGGGCGTACCGCTGAGCGGGGTCGCGCTGCACTTCATGCAACCGTCGGCGGAGCTGGATCAGCTGA
CCCGCGACTTCTTCCACACCCGCCTGTTCGGATTGCCGGCAGCGCTGGCCAGTTATGCGCTGGTCGGCTGGTTCCTCGGC
ACCCAGAATGCCCGGGCGCCGCTGGCTATTCTGCTGAGCACCAACCTGATCAACATCGTGCTCAACCTGTGGTTCGTGAT
TGGCCTGGACTGGGGCGTGGTCGGTTCGGCGCGCGCCTCGGTGATCGCCGAATGGAGCGGCGCCCTGCTCGGTCTGTGGA
TGACTCGCAAGGCTTTGCGCGCCTATCCCGGCCACATCGCCTGGGCCGCCCTGAAACTCTGGCAGAGCTGGCGCCCGCTG
CTGGCGGTCAACCGCGACATTTTCATCCGCAGCCTGGCCCTGCAATCGGTGTTTTTCCTGATCACCGTGCAGGGCGCGCG
ACTGGGCGATGCCACCGTCGCGGCGAACGCGCTGTTGCTCAACGGCCTGCTGTTGACCGCCCACGCGCTGGACGGACTGG
CCCACGCCGTCGAAGCCTTGTGCGGCCACGCCATCGGCGCCCGGGATCGTCTGGCCCTGCGCCGCTCGCTGGTGGTTGCC
GGTGGCTGGTCGTTGCTGGCGAGCCTGGGCTTTGCCGCGCTGTTTCTGTTGGCCGGCCACTTGTTCATCGAAATGCAGAC
CGACATCCAGAGCGTGCGCGAGACCGCGTTCATCTACCTGCCCTATCTGGCCGTGCTGCCGTTGATCGCAGTCTGGAGCT
ACTTGCTCGACGGCTTGTTCATCGGTGCCACCCGCGCCCGGGAAATGCGCAACGGCATGCTGGCGACCGTGATCCTGCTG
CTGCCGGTCGCCTGGGCGCTGCAAGGTCTGGGCAATCACGGCCTGTGGATTTCATTCCTGCTGTTCATGGTGCTGCGCAG
CCTGACGCTCGGGGGACTGGCGTGGTGGCTGCGGCGCACCGATGGCTGGTTCAGCGGTGCCGCTCACTGA

Upstream 100 bases:

>100_bases
ATCATTGCCGGGATCATCTGGTTGCTGCTGGGATTGTGGCTGCTGAGCTGGATCATTCACTGACGCCGCCCGCTACAATG
CCGCTCCTCAAGGAGCCCGC

Downstream 100 bases:

>100_bases
AGCGGCGCCTCACGACGGGTCGTTCAGCCAGCGCCGACGCAACAGTTCGAGCCGCTGCCGTGGGGTCAAACCTTGCGGCA
GCGGTGTCAGCTCGGCACGC

Product: multi anti extrusion protein MatE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSNLITDWRDRPTHRRVWALAAPMILSNISVPLVALVDSTVIGHLPHAHQLGAVAVGASLYTFLAWAMGFLRMGTTGFAA
QAAGRSDGAALRQILLQGLLLAMGLALLLGTLGVPLSGVALHFMQPSAELDQLTRDFFHTRLFGLPAALASYALVGWFLG
TQNARAPLAILLSTNLINIVLNLWFVIGLDWGVVGSARASVIAEWSGALLGLWMTRKALRAYPGHIAWAALKLWQSWRPL
LAVNRDIFIRSLALQSVFFLITVQGARLGDATVAANALLLNGLLLTAHALDGLAHAVEALCGHAIGARDRLALRRSLVVA
GGWSLLASLGFAALFLLAGHLFIEMQTDIQSVRETAFIYLPYLAVLPLIAVWSYLLDGLFIGATRAREMRNGMLATVILL
LPVAWALQGLGNHGLWISFLLFMVLRSLTLGGLAWWLRRTDGWFSGAAH

Sequences:

>Translated_449_residues
MSNLITDWRDRPTHRRVWALAAPMILSNISVPLVALVDSTVIGHLPHAHQLGAVAVGASLYTFLAWAMGFLRMGTTGFAA
QAAGRSDGAALRQILLQGLLLAMGLALLLGTLGVPLSGVALHFMQPSAELDQLTRDFFHTRLFGLPAALASYALVGWFLG
TQNARAPLAILLSTNLINIVLNLWFVIGLDWGVVGSARASVIAEWSGALLGLWMTRKALRAYPGHIAWAALKLWQSWRPL
LAVNRDIFIRSLALQSVFFLITVQGARLGDATVAANALLLNGLLLTAHALDGLAHAVEALCGHAIGARDRLALRRSLVVA
GGWSLLASLGFAALFLLAGHLFIEMQTDIQSVRETAFIYLPYLAVLPLIAVWSYLLDGLFIGATRAREMRNGMLATVILL
LPVAWALQGLGNHGLWISFLLFMVLRSLTLGGLAWWLRRTDGWFSGAAH
>Mature_448_residues
SNLITDWRDRPTHRRVWALAAPMILSNISVPLVALVDSTVIGHLPHAHQLGAVAVGASLYTFLAWAMGFLRMGTTGFAAQ
AAGRSDGAALRQILLQGLLLAMGLALLLGTLGVPLSGVALHFMQPSAELDQLTRDFFHTRLFGLPAALASYALVGWFLGT
QNARAPLAILLSTNLINIVLNLWFVIGLDWGVVGSARASVIAEWSGALLGLWMTRKALRAYPGHIAWAALKLWQSWRPLL
AVNRDIFIRSLALQSVFFLITVQGARLGDATVAANALLLNGLLLTAHALDGLAHAVEALCGHAIGARDRLALRRSLVVAG
GWSLLASLGFAALFLLAGHLFIEMQTDIQSVRETAFIYLPYLAVLPLIAVWSYLLDGLFIGATRAREMRNGMLATVILLL
PVAWALQGLGNHGLWISFLLFMVLRSLTLGGLAWWLRRTDGWFSGAAH

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=452, Percent_Identity=45.353982300885, Blast_Score=278, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48529; Mature: 48398

Theoretical pI: Translated: 11.13; Mature: 11.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SNLITDWRDRPTHRRVWALAAPMILSNISVPLVALVDSTVIGHLPHAHQLGAVAVGASL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
YTFLAWAMGFLRMGTTGFAAQAAGRSDGAALRQILLQGLLLAMGLALLLGTLGVPLSGVA
HHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LHFMQPSAELDQLTRDFFHTRLFGLPAALASYALVGWFLGTQNARAPLAILLSTNLINIV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHH
LNLWFVIGLDWGVVGSARASVIAEWSGALLGLWMTRKALRAYPGHIAWAALKLWQSWRPL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHH
LAVNRDIFIRSLALQSVFFLITVQGARLGDATVAANALLLNGLLLTAHALDGLAHAVEAL
HHHCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGHAIGARDRLALRRSLVVAGGWSLLASLGFAALFLLAGHLFIEMQTDIQSVRETAFIYL
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHH
PYLAVLPLIAVWSYLLDGLFIGATRAREMRNGMLATVILLLPVAWALQGLGNHGLWISFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LFMVLRSLTLGGLAWWLRRTDGWFSGAAH
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]