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The map label for this gene is hutI

Identifier: 77456595

GI number: 77456595

Start: 419775

End: 420980

Strand: Direct

Name: hutI

Synonym: Pfl01_0367

Alternate gene names: 77456595

Gene position: 419775-420980 (Clockwise)

Preceding gene: 77456594

Following gene: 77456596

Centisome position: 6.52

GC content: 64.59

Gene sequence:

>1206_bases
GTGAAAACCCTCTGGCAACACTGCCACGTCGCAACCATGGCGCAAGGCGTCTACTCGATCATCGAGGATGCGGCCATCGT
GACGTCCGGTGCACTCATCGAGTGGATCGGCCCGCGCAGCCAATTGCCGTCAGGCGAATACCCGGCGGTCAATGACCTGC
AAGGCGCGTGGGTCACTCCCGGCCTGATCGACTGCCACACCCACACCGTGTTCGGCGGCAACCGCAGCGGCGAGTTCGAG
AAGCGCCTGCAAGGCGTCAGCTACGCCGAGATCGCAGCAGCCGGCGGCGGCATCGCCAGCACCGTGCGCGCCACACGCGA
AGCCTCGGAAGACGAGCTGTTCGCCAGCGCCGCCAAACGTCTGAAAAGCCTGATGCGCGACGGCGTGACCACGGTCGAAA
TGAAATCCGGCTACGGCCTCGATCTGGCCAGCGAGCGCAAGATCCTGCGGGTCATCCGTCGCCTCGCCGCCGAGCTGCCG
ATCAGCGTGCGCAGCACCTGCCTGGCCGCCCACGCCTTGCCGCCGGAGTACCAGGATCGCGCCGATGATTACATCGATCA
TATCTGCGCCGAAATGCTCCCCGCGCTGGCTGCCGAAGGCCTGGTGGATGCGGTGGATGCCTTCTGCGAATACCTGGCGT
TTTCGCCGGAGCAGGTCGAGCGGGTGTTCATCGCCGCGCAAAAACTCGGTCTGCCGGTGAAGCTGCACGCCGAGCAATTG
TCGTCGCTGCACGGCTCCAGCCTGGCCGCGCGTTATCACGCATTGTCCGCCGATCACCTGGAGTTCATGGACGAAGCCGA
CGCCATCGCCATGGCTGAGTCCGACACCGTCGCGGTGTTGCTGCCGGGCGCGTTCTACTTCCTGCGTGAAACCCGGTTGC
CGCCGATGGAAGCCCTGCGCAAACACAAAGTGAAAATCGCCATCGCCAGCGACCTCAACCCCGGCACCTCGCCAGCGTTG
TCGTTGCGCCTGATGCTGAACATGGCCTGCACCTGTTTCCGCATGACCCCGGAAGAAGCCCTGGCCGGCGCGACCATTCA
TGCGGCACAAGCCCTGGGCATGGCCGAGACCCACGGTTCGCTGGAAGTCGGCAAGGTCGCGGATTTTGTCGCCTGGCAGA
TCGACCGCCCGGCGGATCTGGCGTACTGGCTGGGTGGTGAACTGGACAAACGCGTCGTGCGTCACGGCGTTGAATCAAGT
CTGTAG

Upstream 100 bases:

>100_bases
GAAAGAACAACGCGGTCAGTCCCCTCTCCCTCCGGGAGAGGGTTAGGGTGAGGGGGCTTTTGAAGGCTGCCCACCGAACA
GAATCCAACGGAGGCTCACA

Downstream 100 bases:

>100_bases
GAGAGCGGTTGTGGATAAGGTTCTGAACTTCAAACAAGGTCGCGTGCCGCTGCTGATCAGCATGCCCCACGCCGGTGTGC
GCCTGACCCCGGCGGTCGAG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKTLWQHCHVATMAQGVYSIIEDAAIVTSGALIEWIGPRSQLPSGEYPAVNDLQGAWVTPGLIDCHTHTVFGGNRSGEFE
KRLQGVSYAEIAAAGGGIASTVRATREASEDELFASAAKRLKSLMRDGVTTVEMKSGYGLDLASERKILRVIRRLAAELP
ISVRSTCLAAHALPPEYQDRADDYIDHICAEMLPALAAEGLVDAVDAFCEYLAFSPEQVERVFIAAQKLGLPVKLHAEQL
SSLHGSSLAARYHALSADHLEFMDEADAIAMAESDTVAVLLPGAFYFLRETRLPPMEALRKHKVKIAIASDLNPGTSPAL
SLRLMLNMACTCFRMTPEEALAGATIHAAQALGMAETHGSLEVGKVADFVAWQIDRPADLAYWLGGELDKRVVRHGVESS
L

Sequences:

>Translated_401_residues
MKTLWQHCHVATMAQGVYSIIEDAAIVTSGALIEWIGPRSQLPSGEYPAVNDLQGAWVTPGLIDCHTHTVFGGNRSGEFE
KRLQGVSYAEIAAAGGGIASTVRATREASEDELFASAAKRLKSLMRDGVTTVEMKSGYGLDLASERKILRVIRRLAAELP
ISVRSTCLAAHALPPEYQDRADDYIDHICAEMLPALAAEGLVDAVDAFCEYLAFSPEQVERVFIAAQKLGLPVKLHAEQL
SSLHGSSLAARYHALSADHLEFMDEADAIAMAESDTVAVLLPGAFYFLRETRLPPMEALRKHKVKIAIASDLNPGTSPAL
SLRLMLNMACTCFRMTPEEALAGATIHAAQALGMAETHGSLEVGKVADFVAWQIDRPADLAYWLGGELDKRVVRHGVESS
L
>Mature_401_residues
MKTLWQHCHVATMAQGVYSIIEDAAIVTSGALIEWIGPRSQLPSGEYPAVNDLQGAWVTPGLIDCHTHTVFGGNRSGEFE
KRLQGVSYAEIAAAGGGIASTVRATREASEDELFASAAKRLKSLMRDGVTTVEMKSGYGLDLASERKILRVIRRLAAELP
ISVRSTCLAAHALPPEYQDRADDYIDHICAEMLPALAAEGLVDAVDAFCEYLAFSPEQVERVFIAAQKLGLPVKLHAEQL
SSLHGSSLAARYHALSADHLEFMDEADAIAMAESDTVAVLLPGAFYFLRETRLPPMEALRKHKVKIAIASDLNPGTSPAL
SLRLMLNMACTCFRMTPEEALAGATIHAAQALGMAETHGSLEVGKVADFVAWQIDRPADLAYWLGGELDKRVVRHGVESS
L

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=390, Percent_Identity=38.4615384615385, Blast_Score=229, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17555004, Length=369, Percent_Identity=34.1463414634146, Blast_Score=209, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_PSEPF (Q3KJE5)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_346100.1
- HSSP:   Q8U8Z6
- ProteinModelPortal:   Q3KJE5
- SMR:   Q3KJE5
- STRING:   Q3KJE5
- GeneID:   3713415
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_0367
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   PFLU205922:PFL_0367-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 43335; Mature: 43335

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: BINDING 75-75 BINDING 88-88 BINDING 138-138 BINDING 171-171 BINDING 239-239

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLWQHCHVATMAQGVYSIIEDAAIVTSGALIEWIGPRSQLPSGEYPAVNDLQGAWVTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCC
GLIDCHTHTVFGGNRSGEFEKRLQGVSYAEIAAAGGGIASTVRATREASEDELFASAAKR
CEEECCCEEEECCCCCCCHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHH
LKSLMRDGVTTVEMKSGYGLDLASERKILRVIRRLAAELPISVRSTCLAAHALPPEYQDR
HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHH
ADDYIDHICAEMLPALAAEGLVDAVDAFCEYLAFSPEQVERVFIAAQKLGLPVKLHAEQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECHHHH
SSLHGSSLAARYHALSADHLEFMDEADAIAMAESDTVAVLLPGAFYFLRETRLPPMEALR
HHHCCHHHHHHHHHCCHHHHHHHHCCCCEEEECCCCEEEEECHHHHHHHHCCCCHHHHHH
KHKVKIAIASDLNPGTSPALSLRLMLNMACTCFRMTPEEALAGATIHAAQALGMAETHGS
HCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCHHHCCCC
LEVGKVADFVAWQIDRPADLAYWLGGELDKRVVRHGVESSL
CCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTLWQHCHVATMAQGVYSIIEDAAIVTSGALIEWIGPRSQLPSGEYPAVNDLQGAWVTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCC
GLIDCHTHTVFGGNRSGEFEKRLQGVSYAEIAAAGGGIASTVRATREASEDELFASAAKR
CEEECCCEEEECCCCCCCHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHH
LKSLMRDGVTTVEMKSGYGLDLASERKILRVIRRLAAELPISVRSTCLAAHALPPEYQDR
HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHH
ADDYIDHICAEMLPALAAEGLVDAVDAFCEYLAFSPEQVERVFIAAQKLGLPVKLHAEQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECHHHH
SSLHGSSLAARYHALSADHLEFMDEADAIAMAESDTVAVLLPGAFYFLRETRLPPMEALR
HHHCCHHHHHHHHHCCHHHHHHHHCCCCEEEECCCCEEEEECHHHHHHHHCCCCHHHHHH
KHKVKIAIASDLNPGTSPALSLRLMLNMACTCFRMTPEEALAGATIHAAQALGMAETHGS
HCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCHHHCCCC
LEVGKVADFVAWQIDRPADLAYWLGGELDKRVVRHGVESSL
CCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA