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The map label for this gene is ctaD [H]

Identifier: 77454791

GI number: 77454791

Start: 208340

End: 210106

Strand: Direct

Name: ctaD [H]

Synonym: pREL1_0224

Alternate gene names: 77454791

Gene position: 208340-210106 (Clockwise)

Preceding gene: 77454790

Following gene: 77454792

Centisome position: 76.71

GC content: 60.44

Gene sequence:

>1767_bases
ATGACCGCACTGATTCCCCGCCGAGAAGCAGCCAGGCCGTATCCGGCGCGTAGTGAACCCAAGGGCTCGACACTGTTCCA
GTTGGTGACCACCACCGATCATAAAACGATCGGCAAGATGTATTTGGTCACCTCGTTCGGTCTGTTTCTCATCGGCGGTC
TGATGGCGTTATTGATGCGCGCTGAATTGGCGGTGCCGGGGCTGCAGTTTCTTTCCAACGAGCAGTACAACCAACTCTTC
ACCATGCACGGTACGATCATGCTGTTGCTCTACGCGGTACCGGTGGCCTACGGTTTCGCGAACTACATTCTTCCGCTGCA
GATCGGCGCACCCGATGTCGCATTCCCGCGGCTCAACGCGTTCGCATACTGGTTGTATGTGTTCGGGTCGTTGATCGTGC
TCGCCGGGTTCATCACCCCGGGAGGCGCGGCGGACTTCGGGTGGACCGCTTACACCCCACTGACGAGTGCACTGCATTCA
CCCGGTGTCGGTGCCGACCTGTGGGTACTGGGCCTGATTCTTTCCGGGCTCGGCACCATCTTGGGTGCGGTCAATTTCGT
CACCACCGTCGTCTGTCTACGGGCACCGGGGATGACGATGTTCCGGATGCCGATCTTCACCTGGAACATTCTTGTGACCT
CACTCCTGGTGCTCCTGGCGTTTCCGACCTTCGCCGCTGCACTGGCCGGTCTGGCATTCGATCGCCACTTCGGCGGTCAC
GTGTTCGATCCCGCGACCGGGGGAGCGATGCTCTGGCAGCACCTGTTCTGGTTCTTCGGACACCCCGAGGTCTACATCGT
GGCGCTGCCCTTCTTCGGGATAGTCTCCGAGATCTTCCCCGTCTTCAGTCGCAAACCCATCTTTGGTTACAAGGGATTGA
TCTTCGCCACTCTCGGCATCGCTGCCCTCTCTATCACCGTATGGGCGCATCACATGTACGCCACCGGCGCAGTGTTGCTG
CCGTTCTTCTCGTTCATGTCCTTTCTGATCGCGATACCGACCGGGGTAAAATTGTTCAACTGGGTCGGCACCATGTGGCG
AGGGCAGGTTACCTTGGAGACGCCGATGCTCTTCAGCGTCGGATTTCTGATCACCTTCCTCTTCGGCGGCCTGACCGGGG
TACTGCTCGCTAGCCCTCCGATCGACTTCCATGTCACCGACACTTACTTCGTCGTCGCGCACTTCCACTACGTGCTGTTC
GGCACCATTGTCTTCGCCACCTATGCCGGGGTGTACTTCTGGTTCCCGAAAATCACCGGCCGCATGCTCGACGAACGCCT
CGGCAAGTGGCATTTCTGGACGACCTTCATCGGGTTCCACATGACGTTCCTGGTTCAGCACTGGCTCGGCAGTGAAGGGA
TGCCGCGCCGCTACGCCGACTACCTACCCTCGGACGGCTTCACCACTCTGAACTCAATCTCTTCCATCGGAGCGTTCATC
CTCGGAGCATCGACGTTGCCGTTCGTGTGGAACGTCTTCAAGTCCTACCGCTACGGCGAGCTCGCTATCGTCGACGACCC
CTGGGGATGCGGCAATTCCCTCGAATGGGCCACCACCTGTCCACCGCCGCGCCACAACTTCACCGAGCTCCCCCGGATCC
GTTCCGAGCGGCCGGCATTCGAGCTGCATTACCCGCACATGGTCGACCGGATGCGCACCGAGGCGCACGTGGGCTTGATG
GGCCACACGGCCGGAGTCCGGGCCCCCTCCGAAGTCGTGGCCGACGGTATCGAACACGACACCGCCAGCGAGAGCGACAC
CCGGTGA

Upstream 100 bases:

>100_bases
TCCGCCATGGCCCTGTGATGCACGCCGGCGTCGCCCACCGAGCCCCTTTCTACGCACGCAGTTGCGGGCGCACCCCACAC
CTGGATCGAGGAGATCGTCG

Downstream 100 bases:

>100_bases
CGAGAGATCGTTGCGGCCATCGAGTGGGCGCGAATGTGCTGCTGCCGGGCCGAGGGTCGTACGCCATTGCCTGCGTCATG
GGGTTCTACGTGCTCGCGCT

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1-alpha; Cytochrome c oxidase polypeptide I-alpha [H]

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MTALIPRREAARPYPARSEPKGSTLFQLVTTTDHKTIGKMYLVTSFGLFLIGGLMALLMRAELAVPGLQFLSNEQYNQLF
TMHGTIMLLLYAVPVAYGFANYILPLQIGAPDVAFPRLNAFAYWLYVFGSLIVLAGFITPGGAADFGWTAYTPLTSALHS
PGVGADLWVLGLILSGLGTILGAVNFVTTVVCLRAPGMTMFRMPIFTWNILVTSLLVLLAFPTFAAALAGLAFDRHFGGH
VFDPATGGAMLWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYKGLIFATLGIAALSITVWAHHMYATGAVLL
PFFSFMSFLIAIPTGVKLFNWVGTMWRGQVTLETPMLFSVGFLITFLFGGLTGVLLASPPIDFHVTDTYFVVAHFHYVLF
GTIVFATYAGVYFWFPKITGRMLDERLGKWHFWTTFIGFHMTFLVQHWLGSEGMPRRYADYLPSDGFTTLNSISSIGAFI
LGASTLPFVWNVFKSYRYGELAIVDDPWGCGNSLEWATTCPPPRHNFTELPRIRSERPAFELHYPHMVDRMRTEAHVGLM
GHTAGVRAPSEVVADGIEHDTASESDTR

Sequences:

>Translated_588_residues
MTALIPRREAARPYPARSEPKGSTLFQLVTTTDHKTIGKMYLVTSFGLFLIGGLMALLMRAELAVPGLQFLSNEQYNQLF
TMHGTIMLLLYAVPVAYGFANYILPLQIGAPDVAFPRLNAFAYWLYVFGSLIVLAGFITPGGAADFGWTAYTPLTSALHS
PGVGADLWVLGLILSGLGTILGAVNFVTTVVCLRAPGMTMFRMPIFTWNILVTSLLVLLAFPTFAAALAGLAFDRHFGGH
VFDPATGGAMLWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYKGLIFATLGIAALSITVWAHHMYATGAVLL
PFFSFMSFLIAIPTGVKLFNWVGTMWRGQVTLETPMLFSVGFLITFLFGGLTGVLLASPPIDFHVTDTYFVVAHFHYVLF
GTIVFATYAGVYFWFPKITGRMLDERLGKWHFWTTFIGFHMTFLVQHWLGSEGMPRRYADYLPSDGFTTLNSISSIGAFI
LGASTLPFVWNVFKSYRYGELAIVDDPWGCGNSLEWATTCPPPRHNFTELPRIRSERPAFELHYPHMVDRMRTEAHVGLM
GHTAGVRAPSEVVADGIEHDTASESDTR
>Mature_587_residues
TALIPRREAARPYPARSEPKGSTLFQLVTTTDHKTIGKMYLVTSFGLFLIGGLMALLMRAELAVPGLQFLSNEQYNQLFT
MHGTIMLLLYAVPVAYGFANYILPLQIGAPDVAFPRLNAFAYWLYVFGSLIVLAGFITPGGAADFGWTAYTPLTSALHSP
GVGADLWVLGLILSGLGTILGAVNFVTTVVCLRAPGMTMFRMPIFTWNILVTSLLVLLAFPTFAAALAGLAFDRHFGGHV
FDPATGGAMLWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYKGLIFATLGIAALSITVWAHHMYATGAVLLP
FFSFMSFLIAIPTGVKLFNWVGTMWRGQVTLETPMLFSVGFLITFLFGGLTGVLLASPPIDFHVTDTYFVVAHFHYVLFG
TIVFATYAGVYFWFPKITGRMLDERLGKWHFWTTFIGFHMTFLVQHWLGSEGMPRRYADYLPSDGFTTLNSISSIGAFIL
GASTLPFVWNVFKSYRYGELAIVDDPWGCGNSLEWATTCPPPRHNFTELPRIRSERPAFELHYPHMVDRMRTEAHVGLMG
HTAGVRAPSEVVADGIEHDTASESDTR

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=42.8849902534113, Blast_Score=374, Evalue=1e-103,
Organism=Escherichia coli, GI1786634, Length=522, Percent_Identity=42.911877394636, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=38.4180790960452, Blast_Score=357, Evalue=3e-99,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=39.622641509434, Blast_Score=233, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=244, Percent_Identity=36.8852459016393, Blast_Score=151, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 65187; Mature: 65056

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALIPRREAARPYPARSEPKGSTLFQLVTTTDHKTIGKMYLVTSFGLFLIGGLMALLMR
CCCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AELAVPGLQFLSNEQYNQLFTMHGTIMLLLYAVPVAYGFANYILPLQIGAPDVAFPRLNA
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHH
FAYWLYVFGSLIVLAGFITPGGAADFGWTAYTPLTSALHSPGVGADLWVLGLILSGLGTI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LGAVNFVTTVVCLRAPGMTMFRMPIFTWNILVTSLLVLLAFPTFAAALAGLAFDRHFGGH
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VFDPATGGAMLWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYKGLIFATLGI
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AALSITVWAHHMYATGAVLLPFFSFMSFLIAIPTGVKLFNWVGTMWRGQVTLETPMLFSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCHHHHH
GFLITFLFGGLTGVLLASPPIDFHVTDTYFVVAHFHYVLFGTIVFATYAGVYFWFPKITG
HHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLDERLGKWHFWTTFIGFHMTFLVQHWLGSEGMPRRYADYLPSDGFTTLNSISSIGAFI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
LGASTLPFVWNVFKSYRYGELAIVDDPWGCGNSLEWATTCPPPRHNFTELPRIRSERPAF
HCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCHHCCCCCE
ELHYPHMVDRMRTEAHVGLMGHTAGVRAPSEVVADGIEHDTASESDTR
EEECHHHHHHHHHHHHHCEEECCCCCCCCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TALIPRREAARPYPARSEPKGSTLFQLVTTTDHKTIGKMYLVTSFGLFLIGGLMALLMR
CCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AELAVPGLQFLSNEQYNQLFTMHGTIMLLLYAVPVAYGFANYILPLQIGAPDVAFPRLNA
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHH
FAYWLYVFGSLIVLAGFITPGGAADFGWTAYTPLTSALHSPGVGADLWVLGLILSGLGTI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LGAVNFVTTVVCLRAPGMTMFRMPIFTWNILVTSLLVLLAFPTFAAALAGLAFDRHFGGH
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VFDPATGGAMLWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYKGLIFATLGI
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AALSITVWAHHMYATGAVLLPFFSFMSFLIAIPTGVKLFNWVGTMWRGQVTLETPMLFSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCHHHHH
GFLITFLFGGLTGVLLASPPIDFHVTDTYFVVAHFHYVLFGTIVFATYAGVYFWFPKITG
HHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLDERLGKWHFWTTFIGFHMTFLVQHWLGSEGMPRRYADYLPSDGFTTLNSISSIGAFI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
LGASTLPFVWNVFKSYRYGELAIVDDPWGCGNSLEWATTCPPPRHNFTELPRIRSERPAF
HCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCHHCCCCCE
ELHYPHMVDRMRTEAHVGLMGHTAGVRAPSEVVADGIEHDTASESDTR
EEECHHHHHHHHHHHHHCEEECCCCCCCCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA