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The map label for this gene is lig [H]

Identifier: 75674659

GI number: 75674659

Start: 517624

End: 518796

Strand: Direct

Name: lig [H]

Synonym: Nwi_0461

Alternate gene names: 75674659

Gene position: 517624-518796 (Clockwise)

Preceding gene: 75674649

Following gene: 75674660

Centisome position: 15.21

GC content: 65.22

Gene sequence:

>1173_bases
ATGGGAGATTATTTCAAGGTCGGAGATGACGATCCCTCGCGCGTCTTCCGTCCTGGCTGCGCCCCTTTTCCGCCGCCCGA
CCGATCGAAGGCTCGAACGATACTTGTGGCCGCTTATATGTCTCTCATGCGCCCGCAAGACATCCTGATGCCCGATGCCG
CCGGACTATACTGCAAGCCTGGCGGCTTCCACATCGATCCGGTGCGGCCGGTGGACCGCGCGATCGTCACCCACGGCCAT
TCGGATCATGCCCGGCCCGGACATGGGGCGGTGCTGGCGACACCGGAAACGCTCGACATCATGCGGCTGCGCTACGGAGA
TGATTTCGCGGGCTCCGCGCAGGCGATTTCCTATGGACAAGAGATCAGGCTGGGCGATGTCACGATCAGGTTCCACCCGG
CGGGCCATGTGCTGGGCTCCGCGCAGATCGCGGTCACCCATGGCGGAATCCGCATCGTCATCTCGGGCGATTACAAGGAT
GTCGGCGATCCGACCTGCACGCCGCTCGAGATCGTGCCATGTGATGTCTTCATCACCGAGGCGACTTTCGGGCTGCCGGT
GTTCCGTCATGGCGATGCGGCGTCGGAAACGGGAAAGCTGTTGGCGTCGGTCGCGCTGTTTCCGGAACGAGCGCATCTGG
TTGGCGCTTACTCGCTCGGCAAGGCGCAGCGCGTGATCGCGATGGTTCGCGCGGCCGGATACGACGCGCCGATCTATCTG
CACGGCGCGATGGAGAAGGTGACGCAATACTATCGGAGCCGCGGCATCGCGCTTGGCGACCTGCGTCCGGCCAGGGGTAT
GAAGAAAGCCGATTTCGCGGGCACCATCACCCTGGCTCCGCCCTCGGCCACGGCCGATGTCTGGACACGGCGATTTCCTG
ATCCGGTGAGAGCTTTCGCCTCGGGCTGGATGCGCGTGCGTGCGCGTGCGCGGCAGCGCCGCGTCGAACTGCCGCTGGTC
ATTTCCGATCATGCCGATTGGAACGGCCTGACACGCACCATCGCCGCGACCGGGGCGGGCGAGATCTGGGTGACGCACGG
CCAGGAGGATGCGCTCGTGCATTGGTGCAGGGCGCAAGGTCTCGCCGCGCGCCCGCTGGCATTGGTCGGCTATGGCGATG
AGGACGGCGAGCAGGATGCGGCGGCTTTCTCCGGCGGAGAGGACGGCTCGTGA

Upstream 100 bases:

>100_bases
AGCAGGCGTCCAGCCTGGACAAGCCGTCTGGAAAAATAACGAGAAACGGTCTGCTTTGCCGATCATCGGGAGAATGCGGC
TATTCTCGCCAACGCGCTAA

Downstream 100 bases:

>100_bases
ATCGCTTCGCCGAACTTCTCGACCGTCTCGCCTATGAGCCCGGCCGCAACAACAAGCTGCGGCTGATGACGGCCTATTTT
CGCGAGACGCCGGACCCGGA

Product: hypothetical protein

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MGDYFKVGDDDPSRVFRPGCAPFPPPDRSKARTILVAAYMSLMRPQDILMPDAAGLYCKPGGFHIDPVRPVDRAIVTHGH
SDHARPGHGAVLATPETLDIMRLRYGDDFAGSAQAISYGQEIRLGDVTIRFHPAGHVLGSAQIAVTHGGIRIVISGDYKD
VGDPTCTPLEIVPCDVFITEATFGLPVFRHGDAASETGKLLASVALFPERAHLVGAYSLGKAQRVIAMVRAAGYDAPIYL
HGAMEKVTQYYRSRGIALGDLRPARGMKKADFAGTITLAPPSATADVWTRRFPDPVRAFASGWMRVRARARQRRVELPLV
ISDHADWNGLTRTIAATGAGEIWVTHGQEDALVHWCRAQGLAARPLALVGYGDEDGEQDAAAFSGGEDGS

Sequences:

>Translated_390_residues
MGDYFKVGDDDPSRVFRPGCAPFPPPDRSKARTILVAAYMSLMRPQDILMPDAAGLYCKPGGFHIDPVRPVDRAIVTHGH
SDHARPGHGAVLATPETLDIMRLRYGDDFAGSAQAISYGQEIRLGDVTIRFHPAGHVLGSAQIAVTHGGIRIVISGDYKD
VGDPTCTPLEIVPCDVFITEATFGLPVFRHGDAASETGKLLASVALFPERAHLVGAYSLGKAQRVIAMVRAAGYDAPIYL
HGAMEKVTQYYRSRGIALGDLRPARGMKKADFAGTITLAPPSATADVWTRRFPDPVRAFASGWMRVRARARQRRVELPLV
ISDHADWNGLTRTIAATGAGEIWVTHGQEDALVHWCRAQGLAARPLALVGYGDEDGEQDAAAFSGGEDGS
>Mature_389_residues
GDYFKVGDDDPSRVFRPGCAPFPPPDRSKARTILVAAYMSLMRPQDILMPDAAGLYCKPGGFHIDPVRPVDRAIVTHGHS
DHARPGHGAVLATPETLDIMRLRYGDDFAGSAQAISYGQEIRLGDVTIRFHPAGHVLGSAQIAVTHGGIRIVISGDYKDV
GDPTCTPLEIVPCDVFITEATFGLPVFRHGDAASETGKLLASVALFPERAHLVGAYSLGKAQRVIAMVRAAGYDAPIYLH
GAMEKVTQYYRSRGIALGDLRPARGMKKADFAGTITLAPPSATADVWTRRFPDPVRAFASGWMRVRARARQRRVELPLVI
SDHADWNGLTRTIAATGAGEIWVTHGQEDALVHWCRAQGLAARPLALVGYGDEDGEQDAAAFSGGEDGS

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 41958; Mature: 41827

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDYFKVGDDDPSRVFRPGCAPFPPPDRSKARTILVAAYMSLMRPQDILMPDAAGLYCKP
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCEECC
GGFHIDPVRPVDRAIVTHGHSDHARPGHGAVLATPETLDIMRLRYGDDFAGSAQAISYGQ
CCEECCCCCHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHCCCC
EIRLGDVTIRFHPAGHVLGSAQIAVTHGGIRIVISGDYKDVGDPTCTPLEIVPCDVFITE
EEEEEEEEEEEECCCCEECCEEEEEEECCEEEEEECCCCCCCCCCCCCEEEEECEEEEEC
ATFGLPVFRHGDAASETGKLLASVALFPERAHLVGAYSLGKAQRVIAMVRAAGYDAPIYL
CCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHEEEEHHHCHHHHHHHHHHHCCCCCCEEE
HGAMEKVTQYYRSRGIALGDLRPARGMKKADFAGTITLAPPSATADVWTRRFPDPVRAFA
EHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCHHHHHHH
SGWMRVRARARQRRVELPLVISDHADWNGLTRTIAATGAGEIWVTHGQEDALVHWCRAQG
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHCC
LAARPLALVGYGDEDGEQDAAAFSGGEDGS
CCCCCEEEEECCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
GDYFKVGDDDPSRVFRPGCAPFPPPDRSKARTILVAAYMSLMRPQDILMPDAAGLYCKP
CCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCEECC
GGFHIDPVRPVDRAIVTHGHSDHARPGHGAVLATPETLDIMRLRYGDDFAGSAQAISYGQ
CCEECCCCCHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHCCCC
EIRLGDVTIRFHPAGHVLGSAQIAVTHGGIRIVISGDYKDVGDPTCTPLEIVPCDVFITE
EEEEEEEEEEEECCCCEECCEEEEEEECCEEEEEECCCCCCCCCCCCCEEEEECEEEEEC
ATFGLPVFRHGDAASETGKLLASVALFPERAHLVGAYSLGKAQRVIAMVRAAGYDAPIYL
CCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHEEEEHHHCHHHHHHHHHHHCCCCCCEEE
HGAMEKVTQYYRSRGIALGDLRPARGMKKADFAGTITLAPPSATADVWTRRFPDPVRAFA
EHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCHHHHHHH
SGWMRVRARARQRRVELPLVISDHADWNGLTRTIAATGAGEIWVTHGQEDALVHWCRAQG
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHCC
LAARPLALVGYGDEDGEQDAAAFSGGEDGS
CCCCCEEEEECCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA