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The map label for this gene is htpX [H]

Identifier: 75674388

GI number: 75674388

Start: 218552

End: 219475

Strand: Direct

Name: htpX [H]

Synonym: Nwi_0189

Alternate gene names: 75674388

Gene position: 218552-219475 (Clockwise)

Preceding gene: 75674387

Following gene: 75674389

Centisome position: 6.42

GC content: 66.56

Gene sequence:

>924_bases
ATGAATTATTTTCGTACTGCGATCCTGCTGGCGGGCCTCACCGGCCTGTTCATGGGCGTGGGCTATCTGATCGGCGGCGC
CAGCGGCGCGACGATCGCGCTCGTCGTCGCGGCCGCGACCAACCTCTTCGCCTATTGGAACTCCGACCGCATGGTGCTGT
CGATGTATGGCGCACATGAGGTCGACCCCGGAACCGCGCCCGACCTGCACCGGCTGGTGGCCGAGTTGGCTTCGCGCGCC
GGCCTGCCGATGCCGCGGGTGTTCGTCATGGACAATCCGCAGCCCAACGCGTTCGCCACCGGCCGCAATCCGGAGAATGC
CGCCGTGGCGGTGACGACGGGGCTCATGCAGTCGCTGAGCCGCGAGGAACTGGCCGGCGTGATCGCGCATGAGCTTGCCC
ACATCAAGCATCACGACACGCTGCTGATGACCATTACCGCAACCATCGCCGGCGCGATCTCGATGCTGGCGCAATTCGGC
ATGTTCTTCGGCGGCAACCGCGACAATCACGGCCCCGGCATCATCGGCTCACTGGCGATGATGATCCTCGCGCCGTTCGG
AGCCATGCTGGTGCAGATGGCGATCAGCCGCACGCGCGAATACGCCGCCGACGAAATGGGCGCTCGCATCTGCGGCCAGC
CGATGTGGCTTGCCTCGGCGCTGGCCAGGATCGAGAATGCCGCGCATCAGGTACCAAACATGGAGGCGGAACGCGCGCCC
GCGACCGCGCACATGTTCATCATCAACCCGCTGTCGGGGCGCGGCATGGACAACCTGTTCGCGACCCATCCCTCGACTGA
AAACCGCATCGCGGCATTGCAGAGGCTCGCCGGACAGTCCGGCGGTGGTCTTGCCCCGGGCGGCCCGCCGCCCGACCCGA
GCAGCCCCTGGAACAAGGGTTCTCGCCGCGGTCCATGGGGTTGA

Upstream 100 bases:

>100_bases
CGACCGGCCGCCGCACTTGCGCGCCCTGATACGGAATTCCCATGTTCTGGATGCCGGCCACAATTCCGGCGAGCGTTCGA
CGAGTCTTTCGAGGAATCCG

Downstream 100 bases:

>100_bases
AGGTGCCAGCAGGGTCGTGACCCGCGAGCGAGCGCCAGCATGGCGCGCCTAACATGCGCTCTCGGCGCATCGACCCGCCC
GATCGATCAATCGCATCTTC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNYFRTAILLAGLTGLFMGVGYLIGGASGATIALVVAAATNLFAYWNSDRMVLSMYGAHEVDPGTAPDLHRLVAELASRA
GLPMPRVFVMDNPQPNAFATGRNPENAAVAVTTGLMQSLSREELAGVIAHELAHIKHHDTLLMTITATIAGAISMLAQFG
MFFGGNRDNHGPGIIGSLAMMILAPFGAMLVQMAISRTREYAADEMGARICGQPMWLASALARIENAAHQVPNMEAERAP
ATAHMFIINPLSGRGMDNLFATHPSTENRIAALQRLAGQSGGGLAPGGPPPDPSSPWNKGSRRGPWG

Sequences:

>Translated_307_residues
MNYFRTAILLAGLTGLFMGVGYLIGGASGATIALVVAAATNLFAYWNSDRMVLSMYGAHEVDPGTAPDLHRLVAELASRA
GLPMPRVFVMDNPQPNAFATGRNPENAAVAVTTGLMQSLSREELAGVIAHELAHIKHHDTLLMTITATIAGAISMLAQFG
MFFGGNRDNHGPGIIGSLAMMILAPFGAMLVQMAISRTREYAADEMGARICGQPMWLASALARIENAAHQVPNMEAERAP
ATAHMFIINPLSGRGMDNLFATHPSTENRIAALQRLAGQSGGGLAPGGPPPDPSSPWNKGSRRGPWG
>Mature_307_residues
MNYFRTAILLAGLTGLFMGVGYLIGGASGATIALVVAAATNLFAYWNSDRMVLSMYGAHEVDPGTAPDLHRLVAELASRA
GLPMPRVFVMDNPQPNAFATGRNPENAAVAVTTGLMQSLSREELAGVIAHELAHIKHHDTLLMTITATIAGAISMLAQFG
MFFGGNRDNHGPGIIGSLAMMILAPFGAMLVQMAISRTREYAADEMGARICGQPMWLASALARIENAAHQVPNMEAERAP
ATAHMFIINPLSGRGMDNLFATHPSTENRIAALQRLAGQSGGGLAPGGPPPDPSSPWNKGSRRGPWG

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=215, Percent_Identity=35.3488372093023, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 32380; Mature: 32380

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFRTAILLAGLTGLFMGVGYLIGGASGATIALVVAAATNLFAYWNSDRMVLSMYGAHE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCEEEEECCCCC
VDPGTAPDLHRLVAELASRAGLPMPRVFVMDNPQPNAFATGRNPENAAVAVTTGLMQSLS
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCCCCEEHHHHHHHHHHH
REELAGVIAHELAHIKHHDTLLMTITATIAGAISMLAQFGMFFGGNRDNHGPGIIGSLAM
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
MILAPFGAMLVQMAISRTREYAADEMGARICGQPMWLASALARIENAAHQVPNMEAERAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHCCC
ATAHMFIINPLSGRGMDNLFATHPSTENRIAALQRLAGQSGGGLAPGGPPPDPSSPWNKG
CEEEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SRRGPWG
CCCCCCC
>Mature Secondary Structure
MNYFRTAILLAGLTGLFMGVGYLIGGASGATIALVVAAATNLFAYWNSDRMVLSMYGAHE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCEEEEECCCCC
VDPGTAPDLHRLVAELASRAGLPMPRVFVMDNPQPNAFATGRNPENAAVAVTTGLMQSLS
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCCCCEEHHHHHHHHHHH
REELAGVIAHELAHIKHHDTLLMTITATIAGAISMLAQFGMFFGGNRDNHGPGIIGSLAM
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
MILAPFGAMLVQMAISRTREYAADEMGARICGQPMWLASALARIENAAHQVPNMEAERAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHCCC
ATAHMFIINPLSGRGMDNLFATHPSTENRIAALQRLAGQSGGGLAPGGPPPDPSSPWNKG
CEEEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SRRGPWG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA