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The map label for this gene is ushA [H]

Identifier: 73542932

GI number: 73542932

Start: 3562515

End: 3564236

Strand: Reverse

Name: ushA [H]

Synonym: Reut_A3249

Alternate gene names: 73542932

Gene position: 3564236-3562515 (Counterclockwise)

Preceding gene: 73542933

Following gene: 73542929

Centisome position: 93.63

GC content: 65.33

Gene sequence:

>1722_bases
ATGAACCGACGCGAGTTCCTGCAGGTGCTGGCCATTGCCGGCGCCAGCGGCATGAGCTTCCCCGCCAGCGCGGCCCAGGC
GGCGAAATCCGCCGAGGCCATGTATGACCTGCCGCGCTTCGGCAATGTCCACCTGCTGCACTTCACCGACTGCCACGCAC
AACTGCGGCCGGTGTACTTCCGTGAACCGAACGTCAACCTTGGCATCGGTGCCTATGCCGGCAAGCCACCGCATCTCGTC
GGCGACGCGCTGCTGCGCCATTACGGCATCCGCCCCGGCACGCCGCAGGCGCACGCATTCACATACCTCGACTTCACCGA
GGCTGCGCAGCGCTATGGCAAGGTCGGCGGGTTTGCGCACCTGGCAACGCTGGTCAAGCGCATGAAGGCGAGCCGCCCTG
GCGCGCTGCTGCTCGACGGCGGCGACACGTGGCAGGGCTCCGCCACCGCGCTGTGGACCAAGGGCCAGGACATGGTCGAC
GCGGCGCTCGCGCTCGGCGTCAACGTCATGACGCCGCACTGGGAAATGACGCTCGGCGCCGACCGCGTCAAGCAAATCGT
CGAGAAGGACTTCAAGGACAAGGTTTCGTTTCTCGCGCAGAACATCAAGACCAACGACTTCGGCGATCCGGTTTTCGACC
CGTACGTGATCCGCGACATCAACGGTGTCGCGGTCGCCATCATCGGACAGGCCTTCCCGTACACGCCGATTGCCAATCCG
CGCTACTTCGTGCCGGACTGGACCTTTGGCATCCAGGAAGAAAACCTTCAGCAGGTCATCGACGATGCGCGCACCAAGGG
CGCGCAGGTGGTCGTGCTGCTGTCGCACAACGGCATGGACGTCGACCTGAAGCTTGCCTCGCGCGTGCGCGGGCTCGATG
CGATCCTCGGCGGCCATACCCATGACGGCATGCCGGCGCCGGTGCCGGTGAAGAATGCCGGCGGTACTACGCTCGTCACC
AATGCGGGCTCGAACGGCAAGTTCCTCGGCGTGCTGGACTTCGACGTGAAGAACGGCAAGGTGACGGATTTCCGCTACCG
CCTGCTGCCGGTGTTCGCGAACTACCTTCCGGCCGATCCGGCCATGGACGCGCTGATCACCAAGGTCCGCGCGCCGTACG
AACAGAAACTTGGCGAGGTCCTGGCCGTCAACCGCGGCCTGCTGTACCGGCGCGGCAACTTCAACGGCACCTTCGATCAG
CTGATCCTGGATGGCCTGATGGAAGTGCAGGGCGCACAGATCGCGTTCTCGCCGGGCTTCCGCTGGGGCACCACGCTGCT
GCCGGGCCAGGCCATCACGATGGAACACCTGATGGACCAGACCGCCATCACGTATCCGTACACCACGGTGACGGACATGA
CCGGCGAGACCATCAAGACCATTCTGGAAGACGTAGCCGACAACCTGTTCAACCCGGACCCGTACTACCAGCAGGGCGGC
GACATGGTGCGCGTGGGCGGCCTGCAGTACACCATCGACCCGAACGCCGGCATGGGCAAGCGCATCCGTGACATGCGCCT
GAACGGACAGCCTTTGGACGCCGGCAAAACCTACAAGGTAGCCGGCTGGGCGCCTGTGGCCGAGGAAGCGAAACAAGCCG
GCGGCGCACCGATCTGGGACGTCATGGCCCAATGGCTGCGCGCCAACAAGGAGGTCAGCGCCCGCCCGCTGAACCAGCCG
CGCGTGGTCGGCATGGAGCGAAACCCGGGCATGGCGCCCTGA

Upstream 100 bases:

>100_bases
TTTATCGGCGCGCGGCCAACATGAAACCGATGCCGGAAGCGCCTTGCATGCCCTGCACGGCGCCCACCGGCACGCCGATT
CCACAGGAAGAGACGACGAC

Downstream 100 bases:

>100_bases
TGTTGCGCGCGATCCTCACCCCGCGGGTACGGATTGAAGCGCTCGAAGGAAGTAGGCTACAATCGTCCGCGACGGGCCGA
TAGCTCAGCTGGGAGAGCGC

Product: sulfate thiol esterase SoxB

Products: NA

Alternate protein names: UDP-sugar hydrolase; UDP-sugar diphosphatase; UDP-sugar pyrophosphatase; 5'-nucleotidase; 5'-NT [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MNRREFLQVLAIAGASGMSFPASAAQAAKSAEAMYDLPRFGNVHLLHFTDCHAQLRPVYFREPNVNLGIGAYAGKPPHLV
GDALLRHYGIRPGTPQAHAFTYLDFTEAAQRYGKVGGFAHLATLVKRMKASRPGALLLDGGDTWQGSATALWTKGQDMVD
AALALGVNVMTPHWEMTLGADRVKQIVEKDFKDKVSFLAQNIKTNDFGDPVFDPYVIRDINGVAVAIIGQAFPYTPIANP
RYFVPDWTFGIQEENLQQVIDDARTKGAQVVVLLSHNGMDVDLKLASRVRGLDAILGGHTHDGMPAPVPVKNAGGTTLVT
NAGSNGKFLGVLDFDVKNGKVTDFRYRLLPVFANYLPADPAMDALITKVRAPYEQKLGEVLAVNRGLLYRRGNFNGTFDQ
LILDGLMEVQGAQIAFSPGFRWGTTLLPGQAITMEHLMDQTAITYPYTTVTDMTGETIKTILEDVADNLFNPDPYYQQGG
DMVRVGGLQYTIDPNAGMGKRIRDMRLNGQPLDAGKTYKVAGWAPVAEEAKQAGGAPIWDVMAQWLRANKEVSARPLNQP
RVVGMERNPGMAP

Sequences:

>Translated_573_residues
MNRREFLQVLAIAGASGMSFPASAAQAAKSAEAMYDLPRFGNVHLLHFTDCHAQLRPVYFREPNVNLGIGAYAGKPPHLV
GDALLRHYGIRPGTPQAHAFTYLDFTEAAQRYGKVGGFAHLATLVKRMKASRPGALLLDGGDTWQGSATALWTKGQDMVD
AALALGVNVMTPHWEMTLGADRVKQIVEKDFKDKVSFLAQNIKTNDFGDPVFDPYVIRDINGVAVAIIGQAFPYTPIANP
RYFVPDWTFGIQEENLQQVIDDARTKGAQVVVLLSHNGMDVDLKLASRVRGLDAILGGHTHDGMPAPVPVKNAGGTTLVT
NAGSNGKFLGVLDFDVKNGKVTDFRYRLLPVFANYLPADPAMDALITKVRAPYEQKLGEVLAVNRGLLYRRGNFNGTFDQ
LILDGLMEVQGAQIAFSPGFRWGTTLLPGQAITMEHLMDQTAITYPYTTVTDMTGETIKTILEDVADNLFNPDPYYQQGG
DMVRVGGLQYTIDPNAGMGKRIRDMRLNGQPLDAGKTYKVAGWAPVAEEAKQAGGAPIWDVMAQWLRANKEVSARPLNQP
RVVGMERNPGMAP
>Mature_573_residues
MNRREFLQVLAIAGASGMSFPASAAQAAKSAEAMYDLPRFGNVHLLHFTDCHAQLRPVYFREPNVNLGIGAYAGKPPHLV
GDALLRHYGIRPGTPQAHAFTYLDFTEAAQRYGKVGGFAHLATLVKRMKASRPGALLLDGGDTWQGSATALWTKGQDMVD
AALALGVNVMTPHWEMTLGADRVKQIVEKDFKDKVSFLAQNIKTNDFGDPVFDPYVIRDINGVAVAIIGQAFPYTPIANP
RYFVPDWTFGIQEENLQQVIDDARTKGAQVVVLLSHNGMDVDLKLASRVRGLDAILGGHTHDGMPAPVPVKNAGGTTLVT
NAGSNGKFLGVLDFDVKNGKVTDFRYRLLPVFANYLPADPAMDALITKVRAPYEQKLGEVLAVNRGLLYRRGNFNGTFDQ
LILDGLMEVQGAQIAFSPGFRWGTTLLPGQAITMEHLMDQTAITYPYTTVTDMTGETIKTILEDVADNLFNPDPYYQQGG
DMVRVGGLQYTIDPNAGMGKRIRDMRLNGQPLDAGKTYKVAGWAPVAEEAKQAGGAPIWDVMAQWLRANKEVSARPLNQP
RVVGMERNPGMAP

Specific function: Degradation of external UDP-glucose to uridine monophosphate and glucose-1-phosphate, which can then be used by the cell [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=470, Percent_Identity=24.8936170212766, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.6.1.45; =3.1.3.5 [H]

Molecular weight: Translated: 62512; Mature: 62512

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRREFLQVLAIAGASGMSFPASAAQAAKSAEAMYDLPRFGNVHLLHFTDCHAQLRPVYF
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEE
REPNVNLGIGAYAGKPPHLVGDALLRHYGIRPGTPQAHAFTYLDFTEAAQRYGKVGGFAH
ECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCHHH
LATLVKRMKASRPGALLLDGGDTWQGSATALWTKGQDMVDAALALGVNVMTPHWEMTLGA
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHCCEEECCCEEEECCH
DRVKQIVEKDFKDKVSFLAQNIKTNDFGDPVFDPYVIRDINGVAVAIIGQAFPYTPIANP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCC
RYFVPDWTFGIQEENLQQVIDDARTKGAQVVVLLSHNGMDVDLKLASRVRGLDAILGGHT
CEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHCCCC
HDGMPAPVPVKNAGGTTLVTNAGSNGKFLGVLDFDVKNGKVTDFRYRLLPVFANYLPADP
CCCCCCCCEECCCCCCEEEEECCCCCCEEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCH
AMDALITKVRAPYEQKLGEVLAVNRGLLYRRGNFNGTFDQLILDGLMEVQGAQIAFSPGF
HHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCC
RWGTTLLPGQAITMEHLMDQTAITYPYTTVTDMTGETIKTILEDVADNLFNPDPYYQQGG
CCCCEECCCCHHHHHHHHCCCEEECCCCEEECCCHHHHHHHHHHHHHHCCCCCCHHHCCC
DMVRVGGLQYTIDPNAGMGKRIRDMRLNGQPLDAGKTYKVAGWAPVAEEAKQAGGAPIWD
CEEEECCEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCHHH
VMAQWLRANKEVSARPLNQPRVVGMERNPGMAP
HHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MNRREFLQVLAIAGASGMSFPASAAQAAKSAEAMYDLPRFGNVHLLHFTDCHAQLRPVYF
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEE
REPNVNLGIGAYAGKPPHLVGDALLRHYGIRPGTPQAHAFTYLDFTEAAQRYGKVGGFAH
ECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCHHH
LATLVKRMKASRPGALLLDGGDTWQGSATALWTKGQDMVDAALALGVNVMTPHWEMTLGA
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHCCEEECCCEEEECCH
DRVKQIVEKDFKDKVSFLAQNIKTNDFGDPVFDPYVIRDINGVAVAIIGQAFPYTPIANP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCC
RYFVPDWTFGIQEENLQQVIDDARTKGAQVVVLLSHNGMDVDLKLASRVRGLDAILGGHT
CEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHCCCC
HDGMPAPVPVKNAGGTTLVTNAGSNGKFLGVLDFDVKNGKVTDFRYRLLPVFANYLPADP
CCCCCCCCEECCCCCCEEEEECCCCCCEEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCH
AMDALITKVRAPYEQKLGEVLAVNRGLLYRRGNFNGTFDQLILDGLMEVQGAQIAFSPGF
HHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCC
RWGTTLLPGQAITMEHLMDQTAITYPYTTVTDMTGETIKTILEDVADNLFNPDPYYQQGG
CCCCEECCCCHHHHHHHHCCCEEECCCCEEECCCHHHHHHHHHHHHHHCCCCCCHHHCCC
DMVRVGGLQYTIDPNAGMGKRIRDMRLNGQPLDAGKTYKVAGWAPVAEEAKQAGGAPIWD
CEEEECCEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCHHH
VMAQWLRANKEVSARPLNQPRVVGMERNPGMAP
HHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA