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The map label for this gene is ywrO [H]

Identifier: 73542898

GI number: 73542898

Start: 3527226

End: 3527726

Strand: Reverse

Name: ywrO [H]

Synonym: Reut_A3214

Alternate gene names: 73542898

Gene position: 3527726-3527226 (Counterclockwise)

Preceding gene: 73542900

Following gene: 73542897

Centisome position: 92.68

GC content: 66.07

Gene sequence:

>501_bases
TTGGCAGAGGCGCTCGCCTCACGGCCTCACATTGATGTGCGCGACCTCTATTGCCGCTATGTCGATTACGACATCGACGT
CGTGGCCGAGCAGCGCGCGCTGGCTGCCGCGGACACGGTAGTTCTGCAATACCCGGTGCACTGGTACAGCGTGCCACCGC
TGCTGAAGCTCTGGCTGGATGAAGTGCTGGAGTACGGCTGGGCCTATGGCCCCGGCGGCACGGCGCTGCGCGGCAAATCC
ATGCTCGCTGTGGCGAGCACCGGCGGGACCTTCGACTCCTATGGGCCGGAAGGCAACCACGGCCATCCGATCGAAGCGTT
CCTGCTGCCGCTGGAACAGACGGCGCGCCTGTGCGGCATGGACTGGCTGCCGCCGCAGGTCCTGCACGATGCCGACAACA
CCGACACTCAGGCGCTGGCCGAGCATATTGCGCACGTTTGCAGGCGCATCGGCGCTCATACGGATAGCCCGGTAGCGGCA
GGCGCGGAGGTGCGTGCATGA

Upstream 100 bases:

>100_bases
GCCTAAAATTTCGGACTAAACCGCCGTGACGAAAAGCGAATCTCCGATTGTTGTGATCTATGCGCACCCCACGCCAGGCC
GTTCACGGGTCAATCGCCCG

Downstream 100 bases:

>100_bases
ACCAGCATGATTTCCTGATTGCACTGGTGGTGTTCCTGGTGGCGGCCGTGGTCGCCGTGCCGCTTGCGCGCCGCACCGGG
CTTGGCGCGGTGCTGGGGTA

Product: NAD(P)H dehydrogenase (quinone)

Products: NAD+; NADP+; reduced acceptor

Alternate protein names: GSP14 [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MAEALASRPHIDVRDLYCRYVDYDIDVVAEQRALAAADTVVLQYPVHWYSVPPLLKLWLDEVLEYGWAYGPGGTALRGKS
MLAVASTGGTFDSYGPEGNHGHPIEAFLLPLEQTARLCGMDWLPPQVLHDADNTDTQALAEHIAHVCRRIGAHTDSPVAA
GAEVRA

Sequences:

>Translated_166_residues
MAEALASRPHIDVRDLYCRYVDYDIDVVAEQRALAAADTVVLQYPVHWYSVPPLLKLWLDEVLEYGWAYGPGGTALRGKS
MLAVASTGGTFDSYGPEGNHGHPIEAFLLPLEQTARLCGMDWLPPQVLHDADNTDTQALAEHIAHVCRRIGAHTDSPVAA
GAEVRA
>Mature_165_residues
AEALASRPHIDVRDLYCRYVDYDIDVVAEQRALAAADTVVLQYPVHWYSVPPLLKLWLDEVLEYGWAYGPGGTALRGKSM
LAVASTGGTFDSYGPEGNHGHPIEAFLLPLEQTARLCGMDWLPPQVLHDADNTDTQALAEHIAHVCRRIGAHTDSPVAAG
AEVRA

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=107, Percent_Identity=40.1869158878505, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI4505415, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1786231, Length=151, Percent_Identity=43.7086092715232, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1789750, Length=154, Percent_Identity=37.012987012987, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.2

Molecular weight: Translated: 18119; Mature: 17987

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEALASRPHIDVRDLYCRYVDYDIDVVAEQRALAAADTVVLQYPVHWYSVPPLLKLWLD
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCHHHHCCCHHHHHHHH
EVLEYGWAYGPGGTALRGKSMLAVASTGGTFDSYGPEGNHGHPIEAFLLPLEQTARLCGM
HHHHHCCCCCCCCCEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHEEECHHHHHHHHCC
DWLPPQVLHDADNTDTQALAEHIAHVCRRIGAHTDSPVAAGAEVRA
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEALASRPHIDVRDLYCRYVDYDIDVVAEQRALAAADTVVLQYPVHWYSVPPLLKLWLD
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCHHHHCCCHHHHHHHH
EVLEYGWAYGPGGTALRGKSMLAVASTGGTFDSYGPEGNHGHPIEAFLLPLEQTARLCGM
HHHHHCCCCCCCCCEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHEEECHHHHHHHHCC
DWLPPQVLHDADNTDTQALAEHIAHVCRRIGAHTDSPVAAGAEVRA
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; NADPH; H+; acceptor

Specific reaction: NAD(P)H + H+ + acceptor = NAD(P)+ + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 9298659 [H]