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The map label for this gene is rpoC [H]

Identifier: 73542872

GI number: 73542872

Start: 3489090

End: 3493337

Strand: Reverse

Name: rpoC [H]

Synonym: Reut_A3188

Alternate gene names: 73542872

Gene position: 3493337-3489090 (Counterclockwise)

Preceding gene: 73542873

Following gene: 73542871

Centisome position: 91.77

GC content: 63.04

Gene sequence:

>4248_bases
ATGAAAGCATTGCTCGATCTCTTTAAGCAGGTACAGCAGGAAGAGCAGTTCGACGCGATCAAGATCGGCCTGGCCTCGCC
CGAGAAGATCCGTTCGTGGTCGTACGGTGAAGTCAAGAAGCCGGAAACGATCAACTACCGTACGTTCAAGCCGGAACGCG
ACGGCCTGTTCTGCGCGAAGATCTTTGGCCCGATCAAGGACTACGAGTGCCTGTGCGGCAAGTACAAGCGCCTGAAGCAC
CGTGGCGTGATCTGCGAAAAGTGCGGCGTTGAAGTGACGCTGGCCAAGGTGCGCCGCGAGCGCATGGGCCACATCGAACT
GGCCGCGCCGACCGCGCACATCTGGTTCCTGAAGTCGCTGCCGTCGCGTCTGGGCATGGTCCTGGACATGACGCTGCGCG
ACATCGAACGCGTGCTGTACTTCGAAGCATTCGTGGTGCTCGAACCCGGCATGACCCCGCTCAAGAAGAGCCAGATCATG
TCGGAAGACGACTACCTCGCGAAGTGCGACGAATACGGCGAGGGCGAGTTCGTCGCCATGATGGGTGCCGAGGGCATCCG
TGAACTGCTGCGCGGCATCGACATCGAGAAGCAGATCGAACAGATCCGCGCCGAGCTGCAAGCGACCGGTTCCGAAGCCA
AGATCAAGAAGTTCGCCAAGCGCCTGAAGGTGCTCGAGGCCTTCCAGCGTTCGGGCATCAAGCCCGAGTGGATGATTCTC
GAAGTGCTGCCGGTGCTGCCGCCCGAACTGCGTCCGCTGGTGCCGCTGGACGGTGGCCGCTTCGCGACCTCGGACCTGAA
CGACCTGTATCGCCGCGTCATCAACCGTAACAACCGTCTGAAGCGCCTGCTGGAGCTGAAGGCGCCCGAGATCATCGTGC
GCAACGAAAAGCGCATGCTGCAGGAAGCGGTTGACTCGCTGCTGGACAACGGCCGTCGCGGCAAGGCGATGACTGGTGCC
AACAAGCGTCCGCTGAAGTCCCTGGCCGAAATGATCAAGGGCAAGGGCGGCCGTTTCCGTCAGAACCTGCTGGGCAAGCG
CGTCGACTACTCGGGCCGTTCGGTCATCGTGGTGGGCCCGACGCTTAAGCTGCACCAGTGCGGCCTGCCCAAGCTGATGG
CGCTCGAGCTGTTCAAGCCGTTCATCTTCCACAAGCTGGAAACGATGGGCATCGCCACCACGATCAAGGCGGCGAAGAAG
GAAGTCGAAAGCCAGACGCCGGTGGTGTGGGACATCCTCGAAGAGGTGATCCGCGAGCACCCGGTGATGCTGAACCGTGC
GCCGACGCTGCACCGCCTGGGTATCCAGGCGTTCGAGCCGGTGCTGATCGAAGGCAAGGCCATCCAGTTGCACCCGCTCG
TCTGCGCGGCGTTCAACGCCGACTTCGACGGTGACCAGATGGCTGTCCACGTACCGCTGTCGCTGGAAGCGCAGATGGAA
GCCCGCACGCTGATGCTGGCCTCCAACAACGTGCTGTTCCCGGCCAACGGCGACCCGTCGATCGTCCCGTCGCAAGACGT
GGTGCTGGGTCTGTACTACACGACCCGCGACAAGATCAACGGCAAGGGCGAGGGCATGACCTTTGCCGACATCAGCGAAG
TGATCCGCGCCTACGAGAACAAGGAAGTCGAACTGGCTTCCCGCGTGAACGTGCGTATCACCGAGTATGAGCTGGTCGAC
AAGGATGCCGAAGGCGACGCGCGTTTCGCACCCAAGATCACGCTGCAGGCCACCACGGTCGGCCGCGCGATCCTGTCCGA
GATCCTGCCGAAGGGCCTGCCGTTCTCGGTGCTGAACAAGCCGCTCAAGAAGAAGGAAATCTCGCGCCTGATCAACACGG
CGTTCCGCAAGTGCGGCCTGCGCGAGACCGTGATCTTCGCCGACAAGCTGCTGCAGTCGGGCTTCCGCCTGGCAACGCGC
GCCGGTATCTCGATCGCGATCGACGACATGCTGGTGCCGCCGGCCAAGGAGAAGATCATCTCCGAGGCCTCGGCCAAGGT
GAAGGAATACGACAAGCAGTACATGTCGGGTCTGGTGACGGACCAGGAGCGTTACAACAACGTCGTGGACATCTGGGGCG
CCGCCGGCGACCAGGTGGGCAAGGCGATGATGGAGCAGCTCCAGCACGAAGACGTGGTCGACCGCAACGGCAACACCGTC
AAGCAAGAGTCGTTCAACTCCATCTACATGATGGCCGACTCGGGCGCACGGGGTTCCGCTGCGCAGATCCGCCAGCTGGC
CGGTATGCGTGGCCTGATGGCCAAGCCGGATGGCTCGATCATTGAAACGCCGATTACGGCGAACTTCCGTGAAGGCCTGA
ACGTTCTGCAGTACTTCATCTCGACCCACGGTGCACGTAAGGGTCTGGCTGATACGGCACTGAAGACCGCGAACTCGGGT
TACCTGACCCGTCGTCTGGTCGACGTGACGCAGGATCTGGTCGTGGTGGAAGACGATTGCGGCACCTCCAACGGCGTGGC
CATGAAGGCCCTGGTCGAAGGCGGTGAAGTGATCGAAGCCCTGCGCGATCGTATTCTGGGCCGTGTGACGGTGGCTGACG
TGGTGAACCCTGAAACCCAGGAAACCGCGATCGAAACCGGCACGCTGCTGGACGAAGACCTGGTCGACCTGATCGACGCC
CTCGGCGTCGATGAAGTCAAGGTGCGCACGCCGCTGTCGTGCGACACGCGCTACGGCCTATGCGGCAAGTGCTATGGTCG
CGACCTCGGCCGCGGCGTACTGGTGAACTCCGGCGAGGCGGTGGGCGTGATCGCTGCCCAGTCGATCGGTGAGCCGGGCA
CGCAGCTGACCATGCGTACGTTCCACATCGGTGGTGCGGCATCGCGTGCGGCAGTGGCATCGAGCGTGGAAGCCAAGGCG
ACCGGTACGGTCCGCTTCACGGTGACCATGCGCTACGTGACCAACGCCAAGGGCGAACTGATCGTGATCTCGCGTTCCGG
CGAGGCGCTGATCACCGACGACCACGGCCGCGAGCGCGAGCGCCACAAGATCCCGTACGGCGCCACGCTGCTGGTGCAGG
ACGGCCAGGCCATCAAGGCTGGTACGCAGCTGGCCACGTGGGACGCGCTGACGCGTCCGATCGTGTCGGAGTACACCGGT
ACGACCAAGTTCGAGAACGTCGAAGAGGGCGTGACCGTCGCCAAGCAGATGGACGAAGTCACCGGTCTGTCGACCCTCGT
GGTGATCGACGCCAAGCGCCGCACGGCTGCCACCAAGGGCATTCGCCCGCAGGTGAAGCTGCTCGACGCTAACGGGCAGG
AAGTGAAGATCCCGGGCACGGACCACTCCGTGACCATCGGCTTCCAGGTCGGCGCGCTGATTACCGTGAAGGACGGCCAG
CAGGTGCACGTCGGTGAAGTGCTTGCACGTATCCCGACGGAATCGCAGAAGACTCGTGACATTACCGGTGGTCTGCCGCG
AGTGGCCGAGCTGTTCGAAGCGCGTTCGCCGAAGGACGCCGCCGTGCTGGCGGAAGTCACCGGCACGACTTCGTTCGGCA
AGGACACGAAGGGCAAGCAGCGCCTGGTCATTACTGACCTGGACGGCAATGCCCACGAGTTCCTGATCGCGAAGGAAAAG
CAGGTGCTGGTGCACGACGGCCAGGTGGTGAACAAGGGCGAAATGATCGTGGAAGGTCCGGCGGATCCGCACGACATCCT
GCGCCTGAAGGGCATCGAGGAGCTGGCGCACTACATCGTCGACGAAGTGCAGGACGTGTACCGTCTGCAGGGCGTGAAGA
TCAACGACAAGCACATCGAAGTGATTGTTCGTCAGATGCTGCGCCGCGTGCAGGTGGCTGACGTGGGCGACACCAAGTTC
ATCCCGGGTGAACAGGTGGAGCGCTCGGAACTGCTTGACGAGAACGACCGCGTGATCGCCGAAGGCAAGCGTCCGGCAAC
CTACGAGAACCTGCTGCTCGGTATTACCAAGGCGTCGCTGTCGACCGACAGCTTCATCTCGGCGGCATCGTTCCAGGAAA
CCACGCGCGTGCTGACCGAAGCCGCGATCATGGGCAAGACCGACGACCTGCGTGGTCTGAAGGAAAACGTGATCGTCGGC
CGTCTGATCCCGGCCGGTACCGGCTTGGCCTACCACCGTGCCCGCAAGGCACGCGAGGCGTCCGAGCGCGAACGCGCCCA
GGCGATTGCCGACGAAGAGCAGTCGCTCTTCATCGAGCCGCCGCCCGTGGTGCAGGCGACGACCGAGGGCGAAGGCGACA
ACGCCTGA

Upstream 100 bases:

>100_bases
GTGCCGGCTGCGGCCGGCACTCACCAGTGCAGGATTTCCCACAGAATGAATGCCGCGGTGCCGAACAGAGTTCGGTGCGG
CGGCGAAACAAGGAGTTGCA

Downstream 100 bases:

>100_bases
GTCCCTGCGCTGTAGCGACCCGCCGCGAGGCGGGCACGAAAACCCGGCTGATCCCAGCCGGGTTTTTTTTCGTCCGCGAT
GCGGAGTGACCGCGCGATAA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1415; Mature: 1415

Protein sequence:

>1415_residues
MKALLDLFKQVQQEEQFDAIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVLEPGMTPLKKSQIM
SEDDYLAKCDEYGEGEFVAMMGAEGIRELLRGIDIEKQIEQIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPEWMIL
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGA
NKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKK
EVESQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGKGEGMTFADISEVIRAYENKEVELASRVNVRITEYELVD
KDAEGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATR
AGISIAIDDMLVPPAKEKIISEASAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQHEDVVDRNGNTV
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSG
YLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEALRDRILGRVTVADVVNPETQETAIETGTLLDEDLVDLIDA
LGVDEVKVRTPLSCDTRYGLCGKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
TGTVRFTVTMRYVTNAKGELIVISRSGEALITDDHGRERERHKIPYGATLLVQDGQAIKAGTQLATWDALTRPIVSEYTG
TTKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTAATKGIRPQVKLLDANGQEVKIPGTDHSVTIGFQVGALITVKDGQ
QVHVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGIEELAHYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQVADVGDTKF
IPGEQVERSELLDENDRVIAEGKRPATYENLLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKTDDLRGLKENVIVG
RLIPAGTGLAYHRARKAREASERERAQAIADEEQSLFIEPPPVVQATTEGEGDNA

Sequences:

>Translated_1415_residues
MKALLDLFKQVQQEEQFDAIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVLEPGMTPLKKSQIM
SEDDYLAKCDEYGEGEFVAMMGAEGIRELLRGIDIEKQIEQIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPEWMIL
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGA
NKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKK
EVESQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGKGEGMTFADISEVIRAYENKEVELASRVNVRITEYELVD
KDAEGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATR
AGISIAIDDMLVPPAKEKIISEASAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQHEDVVDRNGNTV
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSG
YLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEALRDRILGRVTVADVVNPETQETAIETGTLLDEDLVDLIDA
LGVDEVKVRTPLSCDTRYGLCGKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
TGTVRFTVTMRYVTNAKGELIVISRSGEALITDDHGRERERHKIPYGATLLVQDGQAIKAGTQLATWDALTRPIVSEYTG
TTKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTAATKGIRPQVKLLDANGQEVKIPGTDHSVTIGFQVGALITVKDGQ
QVHVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGIEELAHYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQVADVGDTKF
IPGEQVERSELLDENDRVIAEGKRPATYENLLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKTDDLRGLKENVIVG
RLIPAGTGLAYHRARKAREASERERAQAIADEEQSLFIEPPPVVQATTEGEGDNA
>Mature_1415_residues
MKALLDLFKQVQQEEQFDAIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVLEPGMTPLKKSQIM
SEDDYLAKCDEYGEGEFVAMMGAEGIRELLRGIDIEKQIEQIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPEWMIL
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGA
NKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKK
EVESQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGKGEGMTFADISEVIRAYENKEVELASRVNVRITEYELVD
KDAEGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATR
AGISIAIDDMLVPPAKEKIISEASAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQHEDVVDRNGNTV
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSG
YLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEALRDRILGRVTVADVVNPETQETAIETGTLLDEDLVDLIDA
LGVDEVKVRTPLSCDTRYGLCGKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
TGTVRFTVTMRYVTNAKGELIVISRSGEALITDDHGRERERHKIPYGATLLVQDGQAIKAGTQLATWDALTRPIVSEYTG
TTKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTAATKGIRPQVKLLDANGQEVKIPGTDHSVTIGFQVGALITVKDGQ
QVHVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGIEELAHYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQVADVGDTKF
IPGEQVERSELLDENDRVIAEGKRPATYENLLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKTDDLRGLKENVIVG
RLIPAGTGLAYHRARKAREASERERAQAIADEEQSLFIEPPPVVQATTEGEGDNA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=935, Percent_Identity=23.7433155080214, Blast_Score=178, Evalue=4e-44,
Organism=Homo sapiens, GI39725938, Length=1116, Percent_Identity=23.7455197132616, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI103471997, Length=600, Percent_Identity=25.3333333333333, Blast_Score=116, Evalue=1e-25,
Organism=Escherichia coli, GI2367335, Length=1397, Percent_Identity=66.571224051539, Blast_Score=1885, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=683, Percent_Identity=25.9150805270864, Blast_Score=169, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71987878, Length=554, Percent_Identity=27.7978339350181, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71998295, Length=358, Percent_Identity=24.5810055865922, Blast_Score=92, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320061, Length=884, Percent_Identity=25.3393665158371, Blast_Score=184, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6324690, Length=688, Percent_Identity=25.8720930232558, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281360912, Length=1052, Percent_Identity=24.1444866920152, Blast_Score=184, Evalue=5e-46,
Organism=Drosophila melanogaster, GI17530899, Length=652, Percent_Identity=25.3067484662577, Blast_Score=167, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 155939; Mature: 155939

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLDLFKQVQQEEQFDAIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCEEEHHHHHHHHCCCEEEECCCHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEAFVVLEPGMTPLKKSQIMSEDDYLAKCDEYGEGEFVAM
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCCCCHHHHHCCCCCCCEEEE
MGAEGIRELLRGIDIEKQIEQIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPEWMIL
ECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRML
EEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHH
QEAVDSLLDNGRRGKAMTGANKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEECC
TLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKKEVESQTPVVWDILEEVIREH
CEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
PVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
CEEECCCCCHHHHCHHHCCCEEEECCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCC
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGKGEGMTFADISEVIRAYEN
EEEEEEECCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
KEVELASRVNVRITEYELVDKDAEGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNK
CCEEEECCCEEEEEEEEEECCCCCCCCEECCEEEEEEHHHHHHHHHHHCCCCCCHHHHCC
PLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATRAGISIAIDDMLVPPAKEKII
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCCHHHHHH
SEASAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQHEDVVDRNGNTV
HHHHHHHHHHHHHHHHHCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEE
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFI
CCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
STHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEA
HHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHCCHHHHHH
LRDRILGRVTVADVVNPETQETAIETGTLLDEDLVDLIDALGVDEVKVRTPLSCDTRYGL
HHHHHHCCEEEHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
CGKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
CHHHHCCCCCCCEEEECCCEEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHCCCCCC
TGTVRFTVTMRYVTNAKGELIVISRSGEALITDDHGRERERHKIPYGATLLVQDGQAIKA
CCEEEEEEEEEEEECCCCCEEEEECCCCEEEECCCCCCHHHCCCCCCEEEEEECCCEEEC
GTQLATWDALTRPIVSEYTGTTKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTAATKG
CCCEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHCC
IRPQVKLLDANGQEVKIPGTDHSVTIGFQVGALITVKDGQQVHVGEVLARIPTESQKTRD
CCCEEEEEECCCCEEEECCCCCEEEEEEEEEEEEEECCCCEEHHHHHHHHCCCCCCCCCC
ITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
CCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCC
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGIEELAHYIVDEVQDVYRLQGVKINDKHIE
EEEEECCEEECCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECHHHHH
VIVRQMLRRVQVADVGDTKFIPGEQVERSELLDENDRVIAEGKRPATYENLLLGITKASL
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCEEECCCCCCCHHHHHEEEEHHCC
STDSFISAASFQETTRVLTEAAIMGKTDDLRGLKENVIVGRLIPAGTGLAYHRARKAREA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCEEEEEECCCCCHHHHHHHHHHHH
SERERAQAIADEEQSLFIEPPPVVQATTEGEGDNA
HHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKALLDLFKQVQQEEQFDAIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCEEEHHHHHHHHCCCEEEECCCHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEAFVVLEPGMTPLKKSQIMSEDDYLAKCDEYGEGEFVAM
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCCCCHHHHHCCCCCCCEEEE
MGAEGIRELLRGIDIEKQIEQIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPEWMIL
ECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRML
EEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHH
QEAVDSLLDNGRRGKAMTGANKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEECC
TLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKKEVESQTPVVWDILEEVIREH
CEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
PVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
CEEECCCCCHHHHCHHHCCCEEEECCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCC
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGKGEGMTFADISEVIRAYEN
EEEEEEECCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
KEVELASRVNVRITEYELVDKDAEGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNK
CCEEEECCCEEEEEEEEEECCCCCCCCEECCEEEEEEHHHHHHHHHHHCCCCCCHHHHCC
PLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATRAGISIAIDDMLVPPAKEKII
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCCHHHHHH
SEASAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQHEDVVDRNGNTV
HHHHHHHHHHHHHHHHHCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEE
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFI
CCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
STHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEA
HHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHCCHHHHHH
LRDRILGRVTVADVVNPETQETAIETGTLLDEDLVDLIDALGVDEVKVRTPLSCDTRYGL
HHHHHHCCEEEHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
CGKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
CHHHHCCCCCCCEEEECCCEEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHCCCCCC
TGTVRFTVTMRYVTNAKGELIVISRSGEALITDDHGRERERHKIPYGATLLVQDGQAIKA
CCEEEEEEEEEEEECCCCCEEEEECCCCEEEECCCCCCHHHCCCCCCEEEEEECCCEEEC
GTQLATWDALTRPIVSEYTGTTKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTAATKG
CCCEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHCC
IRPQVKLLDANGQEVKIPGTDHSVTIGFQVGALITVKDGQQVHVGEVLARIPTESQKTRD
CCCEEEEEECCCCEEEECCCCCEEEEEEEEEEEEEECCCCEEHHHHHHHHCCCCCCCCCC
ITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
CCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCC
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGIEELAHYIVDEVQDVYRLQGVKINDKHIE
EEEEECCEEECCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECHHHHH
VIVRQMLRRVQVADVGDTKFIPGEQVERSELLDENDRVIAEGKRPATYENLLLGITKASL
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCEEECCCCCCCHHHHHEEEEHHCC
STDSFISAASFQETTRVLTEAAIMGKTDDLRGLKENVIVGRLIPAGTGLAYHRARKAREA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCEEEEEECCCCCHHHHHHHHHHHH
SERERAQAIADEEQSLFIEPPPVVQATTEGEGDNA
HHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA