Click here to switch to the map view.

The map label for this gene is recQ [H]

Identifier: 73542870

GI number: 73542870

Start: 3486352

End: 3488199

Strand: Reverse

Name: recQ [H]

Synonym: Reut_A3186

Alternate gene names: 73542870

Gene position: 3488199-3486352 (Counterclockwise)

Preceding gene: 73542871

Following gene: 73542869

Centisome position: 91.64

GC content: 66.18

Gene sequence:

>1848_bases
ATGTCGCAAGCACTGGCGATCCTCAAGGATGTATTCGGCTACCACGCCTTCCGTGGCCGCCAAGGCGAGATCATCGACCA
TGTCGCGACGGGCGGCGACTGCCTGGTGCTGATGCCCACTGGCGGCGGCAAGTCGTTGTGCTACCAGATTCCGGCGCTGC
TGCGCCAGCGCGCAGGCGAGGGCGTAGGCATCGTGGTGTCGCCGCTGATCGCGCTGATGCAGGACCAGGTTGCGGCGCTG
ACCGAGGCCGGCGTACGCGCCTCGGTGCTCAATTCGACGCTGACCAGTTCGGAGGCCTCGGCGGTCGAACGCGATCTGCT
GGCTGGCAGGCTCGAAATCCTCTATGTCGCGCCCGAGCGGTTGATGACCCCGCGCTTTCTCGATCTCCTCGGACGTGCCC
GCGTCGGCCTGTTCGCGATCGACGAGGCGCATTGCGTGTCGCAGTGGGGCCACGATTTCCGGCCGGAGTACATCCAGCTG
TCGGTATTGCACGAGCGCTTCCCGGATGTGCCGCGCATCGCGCTGACGGCGACGGCCGATGCGCTGACGCGCGACGAGAT
CATCGAACGGCTAGCGCTCGACGATGCACGTGTCTTTATCTCGAGCTTCGACCGTCCCAATATCCGCTACCGGATCGTCG
AAAAGGACAACGCGCGCCAGCAACTGCTCGCCTTCATCAAGGCGGAGCACATGGCCGCCGATGGCACGCATGACAGCGGC
ATCGTCTACTGCCTGTCGCGCAAGAAGGTCGAGGACACCGCCGAATGGCTGCAAGGCCATGGTCTCAATGCGCTGCCGTA
CCACGCTGGCATGGATCCGGGCACGCGCCAGCGCCATCAGGCGCGCTTCCGCGAAGAGGAAGGCCTGGTGATGGTCGCGA
CGATCGCTTTCGGCATGGGCATCGACAAGCCCGACGTGCGTTTCGTCGCCCATCTGGACCTGCCCAAGAGCATGGAGGGG
TACTACCAGGAAACCGGCCGTGCCGGGCGCGACGGGTTGCCTGCCAATGCCTGGATGGCCTATGGTCTCGGCGACGTGGT
CCAGCAGAAACGCATGATCGACGAGTCCGAGGCCGACGACGCGTTCAAGCGCGTCTCGTCGTCGAAGCTCGATGCGCTGC
TCGGCCTGTGCGAAACCGCAGGCTGCCGGCGCGTGCGCATCCTGGCCTACTTCAACGAAACCAGCGAGCCCTGCGGCAAT
TGCGACACGTGCCTGGAGCCGCCTGCCACGTGGGACGGCACGCGCGAGGCGCAGATGGCGCTGTCGTGCGTGTACCGTAC
GGCGCAGGCGAGCCGGGTGCACTTCGGCGCCACCCACCTGATCGATGTGCTGCGTGGGAATGCGTCGGAGAAGATCAAGC
AGTGGGGCCATGACAAGGTCTCGACCTTCGGCATTGGCAAGGACCGCTCGGTCCACGAATGGCACACGGTGTTCCGGCAG
CTGATTGCGCAGGGATGGCTGATGATCGACCACGGCGGCCACGGCGCGCTGCTGCTCGGCGAGGGTGCGCGCGAAGTGCT
GAAGGGCGAGCGCCAGATCATCCTGCGCCGGCAGGCCTCCAAGCCGGGCAAGTCTGGCGAGCGCGCTGCGCGCGGCGCGC
GTACCGACCATACGGCGGATATGGATGCCGACACGCTTGCGAACTGGGAAGCGCTGCGCCGGTGGCGCACCGAGGCCGCA
CGCGAGCACGGCGTGCCGGCCTATGTGATCTTCCACGATGCCACCTTGGCCGAACTGGCCCGCACGGCGCCGGGGTCGCT
GTCGGCCATGGAGGGCATTCCCGGTATTGGTGCATCCAAGCTCGAGCGTTATGGGCAGGCGATCGTCGACACCCTGAGCA
GGGTGTAA

Upstream 100 bases:

>100_bases
TTGGACGTGAGAAACATCGGACTGTTTGTTGTTTGGCGGCGGTCAGCGGCTTGCTTAGTGGTATGGTTACGGCTTTTCCG
CTTCAGCAATTCCGTTGTCC

Downstream 100 bases:

>100_bases
GCCGATCGGGTATACGCCTTGACCGTATACGATTCCGCTGCTACCATGCCAGATTCGAGTTTTTGGCTTTGGATTTCGCT
CGCCCGTCGGACATGTGGAC

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MSQALAILKDVFGYHAFRGRQGEIIDHVATGGDCLVLMPTGGGKSLCYQIPALLRQRAGEGVGIVVSPLIALMQDQVAAL
TEAGVRASVLNSTLTSSEASAVERDLLAGRLEILYVAPERLMTPRFLDLLGRARVGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPDVPRIALTATADALTRDEIIERLALDDARVFISSFDRPNIRYRIVEKDNARQQLLAFIKAEHMAADGTHDSG
IVYCLSRKKVEDTAEWLQGHGLNALPYHAGMDPGTRQRHQARFREEEGLVMVATIAFGMGIDKPDVRFVAHLDLPKSMEG
YYQETGRAGRDGLPANAWMAYGLGDVVQQKRMIDESEADDAFKRVSSSKLDALLGLCETAGCRRVRILAYFNETSEPCGN
CDTCLEPPATWDGTREAQMALSCVYRTAQASRVHFGATHLIDVLRGNASEKIKQWGHDKVSTFGIGKDRSVHEWHTVFRQ
LIAQGWLMIDHGGHGALLLGEGAREVLKGERQIILRRQASKPGKSGERAARGARTDHTADMDADTLANWEALRRWRTEAA
REHGVPAYVIFHDATLAELARTAPGSLSAMEGIPGIGASKLERYGQAIVDTLSRV

Sequences:

>Translated_615_residues
MSQALAILKDVFGYHAFRGRQGEIIDHVATGGDCLVLMPTGGGKSLCYQIPALLRQRAGEGVGIVVSPLIALMQDQVAAL
TEAGVRASVLNSTLTSSEASAVERDLLAGRLEILYVAPERLMTPRFLDLLGRARVGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPDVPRIALTATADALTRDEIIERLALDDARVFISSFDRPNIRYRIVEKDNARQQLLAFIKAEHMAADGTHDSG
IVYCLSRKKVEDTAEWLQGHGLNALPYHAGMDPGTRQRHQARFREEEGLVMVATIAFGMGIDKPDVRFVAHLDLPKSMEG
YYQETGRAGRDGLPANAWMAYGLGDVVQQKRMIDESEADDAFKRVSSSKLDALLGLCETAGCRRVRILAYFNETSEPCGN
CDTCLEPPATWDGTREAQMALSCVYRTAQASRVHFGATHLIDVLRGNASEKIKQWGHDKVSTFGIGKDRSVHEWHTVFRQ
LIAQGWLMIDHGGHGALLLGEGAREVLKGERQIILRRQASKPGKSGERAARGARTDHTADMDADTLANWEALRRWRTEAA
REHGVPAYVIFHDATLAELARTAPGSLSAMEGIPGIGASKLERYGQAIVDTLSRV
>Mature_614_residues
SQALAILKDVFGYHAFRGRQGEIIDHVATGGDCLVLMPTGGGKSLCYQIPALLRQRAGEGVGIVVSPLIALMQDQVAALT
EAGVRASVLNSTLTSSEASAVERDLLAGRLEILYVAPERLMTPRFLDLLGRARVGLFAIDEAHCVSQWGHDFRPEYIQLS
VLHERFPDVPRIALTATADALTRDEIIERLALDDARVFISSFDRPNIRYRIVEKDNARQQLLAFIKAEHMAADGTHDSGI
VYCLSRKKVEDTAEWLQGHGLNALPYHAGMDPGTRQRHQARFREEEGLVMVATIAFGMGIDKPDVRFVAHLDLPKSMEGY
YQETGRAGRDGLPANAWMAYGLGDVVQQKRMIDESEADDAFKRVSSSKLDALLGLCETAGCRRVRILAYFNETSEPCGNC
DTCLEPPATWDGTREAQMALSCVYRTAQASRVHFGATHLIDVLRGNASEKIKQWGHDKVSTFGIGKDRSVHEWHTVFRQL
IAQGWLMIDHGGHGALLLGEGAREVLKGERQIILRRQASKPGKSGERAARGARTDHTADMDADTLANWEALRRWRTEAAR
EHGVPAYVIFHDATLAELARTAPGSLSAMEGIPGIGASKLERYGQAIVDTLSRV

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=648, Percent_Identity=34.7222222222222, Blast_Score=354, Evalue=1e-97,
Organism=Homo sapiens, GI14591902, Length=416, Percent_Identity=38.2211538461538, Blast_Score=295, Evalue=6e-80,
Organism=Homo sapiens, GI14591904, Length=416, Percent_Identity=38.2211538461538, Blast_Score=295, Evalue=6e-80,
Organism=Homo sapiens, GI148612816, Length=426, Percent_Identity=40.6103286384976, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI51242947, Length=397, Percent_Identity=40.8060453400504, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI169218196, Length=514, Percent_Identity=34.6303501945525, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI51242943, Length=397, Percent_Identity=40.8060453400504, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI110735439, Length=514, Percent_Identity=34.6303501945525, Blast_Score=259, Evalue=7e-69,
Organism=Homo sapiens, GI284005309, Length=345, Percent_Identity=37.1014492753623, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI148613856, Length=347, Percent_Identity=25.0720461095101, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI38201710, Length=347, Percent_Identity=25.0720461095101, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI48994977, Length=612, Percent_Identity=45.9150326797386, Blast_Score=533, Evalue=1e-152,
Organism=Escherichia coli, GI1788930, Length=310, Percent_Identity=24.1935483870968, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082221, Length=336, Percent_Identity=22.9166666666667, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=506, Percent_Identity=38.1422924901186, Blast_Score=323, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI71987997, Length=413, Percent_Identity=40.4358353510896, Blast_Score=302, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI71987993, Length=413, Percent_Identity=40.4358353510896, Blast_Score=302, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI32564293, Length=673, Percent_Identity=31.2035661218425, Blast_Score=291, Evalue=8e-79,
Organism=Caenorhabditis elegans, GI17552866, Length=441, Percent_Identity=36.734693877551, Blast_Score=258, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI71987143, Length=328, Percent_Identity=23.4756097560976, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=540, Percent_Identity=35.7407407407407, Blast_Score=341, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6324217, Length=320, Percent_Identity=23.125, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24646066, Length=633, Percent_Identity=36.8088467614534, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24664226, Length=472, Percent_Identity=36.0169491525424, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24664230, Length=472, Percent_Identity=36.0169491525424, Blast_Score=256, Evalue=5e-68,
Organism=Drosophila melanogaster, GI62472181, Length=450, Percent_Identity=36.8888888888889, Blast_Score=255, Evalue=8e-68,
Organism=Drosophila melanogaster, GI21358123, Length=355, Percent_Identity=37.7464788732394, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI28574962, Length=330, Percent_Identity=26.0606060606061, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18857967, Length=375, Percent_Identity=24.5333333333333, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644479, Length=362, Percent_Identity=22.6519337016575, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281361218, Length=362, Percent_Identity=22.6519337016575, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644481, Length=362, Percent_Identity=22.6519337016575, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644483, Length=362, Percent_Identity=22.6519337016575, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24644487, Length=362, Percent_Identity=22.6519337016575, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45551833, Length=362, Percent_Identity=22.6519337016575, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24644485, Length=362, Percent_Identity=22.6519337016575, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 67694; Mature: 67563

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQALAILKDVFGYHAFRGRQGEIIDHVATGGDCLVLMPTGGGKSLCYQIPALLRQRAGE
CCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
GVGIVVSPLIALMQDQVAALTEAGVRASVLNSTLTSSEASAVERDLLAGRLEILYVAPER
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECHHH
LMTPRFLDLLGRARVGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATAD
HCCHHHHHHHHHHHCCEEEECHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCEEEEECHH
ALTRDEIIERLALDDARVFISSFDRPNIRYRIVEKDNARQQLLAFIKAEHMAADGTHDSG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCC
IVYCLSRKKVEDTAEWLQGHGLNALPYHAGMDPGTRQRHQARFREEEGLVMVATIAFGMG
EEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSMEGYYQETGRAGRDGLPANAWMAYGLGDVVQQKRMIDESEADD
CCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCHHHH
AFKRVSSSKLDALLGLCETAGCRRVRILAYFNETSEPCGNCDTCLEPPATWDGTREAQMA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LSCVYRTAQASRVHFGATHLIDVLRGNASEKIKQWGHDKVSTFGIGKDRSVHEWHTVFRQ
HHHHHHHHHHCCEECCHHHHHHHHHCCHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHH
LIAQGWLMIDHGGHGALLLGEGAREVLKGERQIILRRQASKPGKSGERAARGARTDHTAD
HHHCCCEEEEECCCEEEEECCCHHHHHCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCC
MDADTLANWEALRRWRTEAAREHGVPAYVIFHDATLAELARTAPGSLSAMEGIPGIGASK
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCHHHCCCCCCCHHH
LERYGQAIVDTLSRV
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQALAILKDVFGYHAFRGRQGEIIDHVATGGDCLVLMPTGGGKSLCYQIPALLRQRAGE
CHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
GVGIVVSPLIALMQDQVAALTEAGVRASVLNSTLTSSEASAVERDLLAGRLEILYVAPER
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECHHH
LMTPRFLDLLGRARVGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATAD
HCCHHHHHHHHHHHCCEEEECHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCEEEEECHH
ALTRDEIIERLALDDARVFISSFDRPNIRYRIVEKDNARQQLLAFIKAEHMAADGTHDSG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCC
IVYCLSRKKVEDTAEWLQGHGLNALPYHAGMDPGTRQRHQARFREEEGLVMVATIAFGMG
EEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSMEGYYQETGRAGRDGLPANAWMAYGLGDVVQQKRMIDESEADD
CCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCHHHH
AFKRVSSSKLDALLGLCETAGCRRVRILAYFNETSEPCGNCDTCLEPPATWDGTREAQMA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LSCVYRTAQASRVHFGATHLIDVLRGNASEKIKQWGHDKVSTFGIGKDRSVHEWHTVFRQ
HHHHHHHHHHCCEECCHHHHHHHHHCCHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHH
LIAQGWLMIDHGGHGALLLGEGAREVLKGERQIILRRQASKPGKSGERAARGARTDHTAD
HHHCCCEEEEECCCEEEEECCCHHHHHCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCC
MDADTLANWEALRRWRTEAAREHGVPAYVIFHDATLAELARTAPGSLSAMEGIPGIGASK
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCHHHCCCCCCCHHH
LERYGQAIVDTLSRV
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]