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The map label for this gene is dsbD [H]

Identifier: 73542835

GI number: 73542835

Start: 3462685

End: 3464604

Strand: Reverse

Name: dsbD [H]

Synonym: Reut_A3151

Alternate gene names: 73542835

Gene position: 3464604-3462685 (Counterclockwise)

Preceding gene: 73542836

Following gene: 73542831

Centisome position: 91.02

GC content: 68.39

Gene sequence:

>1920_bases
ATGAGCATGGGTTTTGCGCTTTTGGCGCGGTCATACGGGGCGGGCTGGGCGCGGCATATCGCCGCAGTGCTGGCGGTGAT
GGTGGCCTGGTTGTGCCTGGTCACTGGCGCCCATGCGGCCACGGAAGACGATTTCCTGCCCCCTGAGCAGGCCTTTCGCT
TTGCCGCCCGGCAGATCGACCCTCAGACCATTGAAGTGCGCTTCGACGTGGCAAGCGGCTATTACCTGTACCGGGAGCGC
TTTGCCTTTGCCGCCCGGCCCGACACTGTCCGCCTGGGCCAGCCCGAATTTCCTCACGGCAAGGTGAAGTTCGACGAGAC
GTTCGGCAAGGAGATGGAAACCTACCGCGATGCGGTGGTGATCCGCTTGCCGGTCCAGTCCGCGCCGGCTGATGGCAAAT
GGTCGCTCGTCGTCACGTCCCAGGGCTGTGCCGACAAGGGACTCTGCTATCCGCCGATGGAAAGCGTCTACAAGGTGGGT
GGCTCGCCCTTGGGGAACCTGTTCGCCGACAGGCCGCGCAGCGAGGCGACCGTGCCGCCGGCAGCGTCGGCGAGGCCCGG
TACGGAAGCCGTTGCGCCCCCCGCGCGCCTCGACGAGAACGACCGCATCGCCGGCGTCCTGGCCAGCCGCAACCTTGGCG
TCGTCCTCGCATTGTTCTTTGGCCTTGGCCTGCTGCTGACGTTCACGCCTTGTGTGCTGCCGATGGTGCCCATCCTGTCG
TCCATCGTCGTCGGCGAGCACGCGACGCGCAGCCGTGCGCTGGTGGTGTCGCTGGCCTATGTGCTCGGCATGGCCGTCGT
CTATACGGCGATTGGCGTTGCCGCAGGCCTGCTCGGCGAGGGCCTGGCCGCAGCGCTGCAGACCCCGGCCGTGCTGGCCG
CGTTCGCGGCGCTGATGGTGGCGCTGTCGCTGTCGATGTTCGGGCTCTACGAGCTTCAGCTGCCGCAGCATTGGCAGACC
CGCTTGACGGCCACATCAAACCGCCGCCAGGGCGGGCAAGTGATCGGCGCCGCGGCCATGGGCGCGATCTCCGCGCTGAT
CGTCGGGCCGTGCGTGACGGCACCGCTAGCCGGTGCGCTCGCGTATATCGCGCAGACCCGCGATGCGGTAACCGGCGGCA
CCGCGCTGCTGGCCATGGCACTGGGAATGGGTGTTCCGCTGGTGCTCGTTGGCGTGGGCGCAGGCAATCTGCTGCCCCGC
GCCGGGCACTGGATGGAGGCCACCAAGCGCTTCTTCGGCTTCCTGCTGCTGGGCGTGGCGATCTGGATGGTGACGCCGGT
GCTGCCGGCGTGGCTGACCATGGCGCTGTGGGCCGCGTTGCTGCTGGTGGCTGCGGTGTTCCTGGGCGCGTTTGATGCGC
TCGGTGCTGAGGCCCGCGGCCTGGCGAGGCTGGGCAAGGGACTGGGTGTACTGGCGGCGCTGGCGGGTGCGATCCTGCTG
CTGGGACTGGCCTCGGGTGGCCGGGATCCGCTGCAGCCGTTGGCGCACCTGAGCTTGGCACGCGTCGCTGGCGGTGGAGC
GGAGACGGCGGCAGGACCGCAGTCCGTGCGCTTCGAGCGCGTCCGCAGCGTCGCGGAACTGGATGCACGCGTGGCCCAGG
CAGCGGCCGCCGGCAAGCCCGTGCTGCTCGACTTCTACGCGGACTGGTGCGTAAGTTGCAAGGAAATGGAACACCTGACC
TTCACGGACGCCAAGGTTCGGGCGCGCATGTCGGAAATCGTGCTGCTGCAGGCTGACGTGACCGCCAACAACGCCGATGA
CAAGGCGCTGCTCAAGCGCTTCGGCCTGTTCGGTCCGCCGGGGATCATCCTGTTCGGCGCCGATGGCCGCGAACGGCCTG
TGCGCGTGATCGGCTACCAGTCCGCAGGCCGCTTCCTGGACAGCCTGGAGCGTGCGTTCGGTACACGCCCCAGCACCTGA

Upstream 100 bases:

>100_bases
CGCATGGGTGCGGGGCGAGGTAACTCGCGCCGAGCAACACAAGGATTGAGGCGCCAGGCACACAGCATCGCAGAGTGACA
GAAAGGATTCAGGACGGTCT

Downstream 100 bases:

>100_bases
GCCCTACCGCTCCAACTGCCGCCCAAGTCCCCATACGGCGGCCAGTATCACCACCACCGCGCCCATCAGGCCGATCGACC
ACCAGAACCCGTCGGGCTCG

Product: protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MSMGFALLARSYGAGWARHIAAVLAVMVAWLCLVTGAHAATEDDFLPPEQAFRFAARQIDPQTIEVRFDVASGYYLYRER
FAFAARPDTVRLGQPEFPHGKVKFDETFGKEMETYRDAVVIRLPVQSAPADGKWSLVVTSQGCADKGLCYPPMESVYKVG
GSPLGNLFADRPRSEATVPPAASARPGTEAVAPPARLDENDRIAGVLASRNLGVVLALFFGLGLLLTFTPCVLPMVPILS
SIVVGEHATRSRALVVSLAYVLGMAVVYTAIGVAAGLLGEGLAAALQTPAVLAAFAALMVALSLSMFGLYELQLPQHWQT
RLTATSNRRQGGQVIGAAAMGAISALIVGPCVTAPLAGALAYIAQTRDAVTGGTALLAMALGMGVPLVLVGVGAGNLLPR
AGHWMEATKRFFGFLLLGVAIWMVTPVLPAWLTMALWAALLLVAAVFLGAFDALGAEARGLARLGKGLGVLAALAGAILL
LGLASGGRDPLQPLAHLSLARVAGGGAETAAGPQSVRFERVRSVAELDARVAQAAAAGKPVLLDFYADWCVSCKEMEHLT
FTDAKVRARMSEIVLLQADVTANNADDKALLKRFGLFGPPGIILFGADGRERPVRVIGYQSAGRFLDSLERAFGTRPST

Sequences:

>Translated_639_residues
MSMGFALLARSYGAGWARHIAAVLAVMVAWLCLVTGAHAATEDDFLPPEQAFRFAARQIDPQTIEVRFDVASGYYLYRER
FAFAARPDTVRLGQPEFPHGKVKFDETFGKEMETYRDAVVIRLPVQSAPADGKWSLVVTSQGCADKGLCYPPMESVYKVG
GSPLGNLFADRPRSEATVPPAASARPGTEAVAPPARLDENDRIAGVLASRNLGVVLALFFGLGLLLTFTPCVLPMVPILS
SIVVGEHATRSRALVVSLAYVLGMAVVYTAIGVAAGLLGEGLAAALQTPAVLAAFAALMVALSLSMFGLYELQLPQHWQT
RLTATSNRRQGGQVIGAAAMGAISALIVGPCVTAPLAGALAYIAQTRDAVTGGTALLAMALGMGVPLVLVGVGAGNLLPR
AGHWMEATKRFFGFLLLGVAIWMVTPVLPAWLTMALWAALLLVAAVFLGAFDALGAEARGLARLGKGLGVLAALAGAILL
LGLASGGRDPLQPLAHLSLARVAGGGAETAAGPQSVRFERVRSVAELDARVAQAAAAGKPVLLDFYADWCVSCKEMEHLT
FTDAKVRARMSEIVLLQADVTANNADDKALLKRFGLFGPPGIILFGADGRERPVRVIGYQSAGRFLDSLERAFGTRPST
>Mature_638_residues
SMGFALLARSYGAGWARHIAAVLAVMVAWLCLVTGAHAATEDDFLPPEQAFRFAARQIDPQTIEVRFDVASGYYLYRERF
AFAARPDTVRLGQPEFPHGKVKFDETFGKEMETYRDAVVIRLPVQSAPADGKWSLVVTSQGCADKGLCYPPMESVYKVGG
SPLGNLFADRPRSEATVPPAASARPGTEAVAPPARLDENDRIAGVLASRNLGVVLALFFGLGLLLTFTPCVLPMVPILSS
IVVGEHATRSRALVVSLAYVLGMAVVYTAIGVAAGLLGEGLAAALQTPAVLAAFAALMVALSLSMFGLYELQLPQHWQTR
LTATSNRRQGGQVIGAAAMGAISALIVGPCVTAPLAGALAYIAQTRDAVTGGTALLAMALGMGVPLVLVGVGAGNLLPRA
GHWMEATKRFFGFLLLGVAIWMVTPVLPAWLTMALWAALLLVAAVFLGAFDALGAEARGLARLGKGLGVLAALAGAILLL
GLASGGRDPLQPLAHLSLARVAGGGAETAAGPQSVRFERVRSVAELDARVAQAAAAGKPVLLDFYADWCVSCKEMEHLTF
TDAKVRARMSEIVLLQADVTANNADDKALLKRFGLFGPPGIILFGADGRERPVRVIGYQSAGRFLDSLERAFGTRPST

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=587, Percent_Identity=38.5008517887564, Blast_Score=353, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 67141; Mature: 67010

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMGFALLARSYGAGWARHIAAVLAVMVAWLCLVTGAHAATEDDFLPPEQAFRFAARQID
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
PQTIEVRFDVASGYYLYRERFAFAARPDTVRLGQPEFPHGKVKFDETFGKEMETYRDAVV
CCEEEEEEEECCCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHCEEE
IRLPVQSAPADGKWSLVVTSQGCADKGLCYPPMESVYKVGGSPLGNLFADRPRSEATVPP
EEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHHCCCCCCCCCCC
AASARPGTEAVAPPARLDENDRIAGVLASRNLGVVLALFFGLGLLLTFTPCVLPMVPILS
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVVGEHATRSRALVVSLAYVLGMAVVYTAIGVAAGLLGEGLAAALQTPAVLAAFAALMV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
ALSLSMFGLYELQLPQHWQTRLTATSNRRQGGQVIGAAAMGAISALIVGPCVTAPLAGAL
HHHHHHHHHEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYIAQTRDAVTGGTALLAMALGMGVPLVLVGVGAGNLLPRAGHWMEATKRFFGFLLLGVA
HHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IWMVTPVLPAWLTMALWAALLLVAAVFLGAFDALGAEARGLARLGKGLGVLAALAGAILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGLASGGRDPLQPLAHLSLARVAGGGAETAAGPQSVRFERVRSVAELDARVAQAAAAGKP
HHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLLDFYADWCVSCKEMEHLTFTDAKVRARMSEIVLLQADVTANNADDKALLKRFGLFGPP
EEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHCCCCCCC
GIILFGADGRERPVRVIGYQSAGRFLDSLERAFGTRPST
CEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SMGFALLARSYGAGWARHIAAVLAVMVAWLCLVTGAHAATEDDFLPPEQAFRFAARQID
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
PQTIEVRFDVASGYYLYRERFAFAARPDTVRLGQPEFPHGKVKFDETFGKEMETYRDAVV
CCEEEEEEEECCCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHCEEE
IRLPVQSAPADGKWSLVVTSQGCADKGLCYPPMESVYKVGGSPLGNLFADRPRSEATVPP
EEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHHCCCCCCCCCCC
AASARPGTEAVAPPARLDENDRIAGVLASRNLGVVLALFFGLGLLLTFTPCVLPMVPILS
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVVGEHATRSRALVVSLAYVLGMAVVYTAIGVAAGLLGEGLAAALQTPAVLAAFAALMV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
ALSLSMFGLYELQLPQHWQTRLTATSNRRQGGQVIGAAAMGAISALIVGPCVTAPLAGAL
HHHHHHHHHEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYIAQTRDAVTGGTALLAMALGMGVPLVLVGVGAGNLLPRAGHWMEATKRFFGFLLLGVA
HHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IWMVTPVLPAWLTMALWAALLLVAAVFLGAFDALGAEARGLARLGKGLGVLAALAGAILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGLASGGRDPLQPLAHLSLARVAGGGAETAAGPQSVRFERVRSVAELDARVAQAAAAGKP
HHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLLDFYADWCVSCKEMEHLTFTDAKVRARMSEIVLLQADVTANNADDKALLKRFGLFGPP
EEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHCCCCCCC
GIILFGADGRERPVRVIGYQSAGRFLDSLERAFGTRPST
CEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]