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The map label for this gene is 73542634

Identifier: 73542634

GI number: 73542634

Start: 3235606

End: 3236454

Strand: Reverse

Name: 73542634

Synonym: Reut_A2950

Alternate gene names: NA

Gene position: 3236454-3235606 (Counterclockwise)

Preceding gene: 73542635

Following gene: 73542633

Centisome position: 85.02

GC content: 64.78

Gene sequence:

>849_bases
ATGACTGTCGACACGCGTCCGGCCGTGGGCAATCCGGGCTATGCCACCTCGTCGCCCGAGCTTGAGCGCTGGCTGGCGCG
GCATATTTCCGAGGGCTTTGGCGCCGAATCGCTTGTGCTTTCCATGCTGCGGTCTGGCTATGACGCCGCGTTCGCGCGCA
GCGCCGTGGCCACGGCAATGGGCCATCGTCGTCCCGATGCGTCGGCTACTCAACCCGCGCCACGTCTCGCCCGGCGCGAA
GTTCCCGTGCTGTTTTCCCTGCAGTCGCCGAGCATCCGTCTGTACCAACACTTGTTGAGCGATGCCGAGTGCGATGCGCT
GGTCGAACTCGCACGCGGACGCCTTGCGCGTTCGCCGGTGATCAACCCGGATACTGGCGACGAGAACCTGATCGATGCGC
GCACCAGCATGGGTGCCATGTTCCAGGTGGGCGAGCACACGCTGATCCAGCGCATCGAGGACCGCATTGCCGCCGTGCTC
GGCGTACCCGTCGACCATGGGGAAGGCTTGCAGATACTCAACTACAAGCCGGGCGGCGAATACCAGCCGCATTTCGATTT
CTTCAATCCGAAGCGCCCCGGCGAGGCACGCCAGCTCCGCGTAGGCGGCCAGCGCACTGCGACGCTCGTGATCTACCTGA
ACACGCCGCAGGCGGGCGGCGCAACGGCGTTCCCGCGCATCGGCCTGGAAGTGGCGCCGGTCAAGGGCAACGCTGTGTAC
TTCAGTTATCTGCAACCCGACGGCAAGCTCGACGAACGTACGTTGCACGCCGGCCTGCCGGTGCAATCGGGCGAAAAATG
GATCGCTACCAAGTGGCTGCGTGAGCACCCATATCGCGCAGGCGCATAA

Upstream 100 bases:

>100_bases
TCGCGGGCGACCCGGAGAACGCGCCGACCCGTCCGCGCAAGCTGCTGCCCGAGGCGCCCGCGCGTAACCCGTTCTCGCCG
CAGCGCCTGGCCAATCCGTC

Downstream 100 bases:

>100_bases
CGACCGGCCCGCTGTACGGCGCACTGCCGTCACGGAAGAATTTCGCGAAACTGTACCGGTACTGTACTGTTAGCTGTGAC
TAGACTGGCAGCAATCCCCC

Product: procollagen-proline, 2-oxoglutarate-4-dioxygenase

Products: NA

Alternate protein names: 2OG-Fe(II) Oxygenase; Prolyl 4-Hydroxylase Alpha Subunit; Oxidoreductase 2OG-Fe(II) Oxygenase Family; Oxygenase; Procollagen-Proline 2-Oxoglutarate-4-Dioxygenase; Response Regulator Receiver Domain-Containing Protein; 2OG-Fe(II) Oxygenase Family Oxidoreductase; Prolyl 4-Hydroxylase Subunit Alpha; 2OG-Fe(II) Oxygenase Superfamily Protein; 2OG-Fe(II) Oxygenase Family Protein; Procollagen-Proline 2-Oxoglutarate-4- Dioxygenase; Prolyl 4-Hydroxylase

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTVDTRPAVGNPGYATSSPELERWLARHISEGFGAESLVLSMLRSGYDAAFARSAVATAMGHRRPDASATQPAPRLARRE
VPVLFSLQSPSIRLYQHLLSDAECDALVELARGRLARSPVINPDTGDENLIDARTSMGAMFQVGEHTLIQRIEDRIAAVL
GVPVDHGEGLQILNYKPGGEYQPHFDFFNPKRPGEARQLRVGGQRTATLVIYLNTPQAGGATAFPRIGLEVAPVKGNAVY
FSYLQPDGKLDERTLHAGLPVQSGEKWIATKWLREHPYRAGA

Sequences:

>Translated_282_residues
MTVDTRPAVGNPGYATSSPELERWLARHISEGFGAESLVLSMLRSGYDAAFARSAVATAMGHRRPDASATQPAPRLARRE
VPVLFSLQSPSIRLYQHLLSDAECDALVELARGRLARSPVINPDTGDENLIDARTSMGAMFQVGEHTLIQRIEDRIAAVL
GVPVDHGEGLQILNYKPGGEYQPHFDFFNPKRPGEARQLRVGGQRTATLVIYLNTPQAGGATAFPRIGLEVAPVKGNAVY
FSYLQPDGKLDERTLHAGLPVQSGEKWIATKWLREHPYRAGA
>Mature_281_residues
TVDTRPAVGNPGYATSSPELERWLARHISEGFGAESLVLSMLRSGYDAAFARSAVATAMGHRRPDASATQPAPRLARREV
PVLFSLQSPSIRLYQHLLSDAECDALVELARGRLARSPVINPDTGDENLIDARTSMGAMFQVGEHTLIQRIEDRIAAVLG
VPVDHGEGLQILNYKPGGEYQPHFDFFNPKRPGEARQLRVGGQRTATLVIYLNTPQAGGATAFPRIGLEVAPVKGNAVYF
SYLQPDGKLDERTLHAGLPVQSGEKWIATKWLREHPYRAGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI217272849, Length=187, Percent_Identity=40.1069518716578, Blast_Score=141, Evalue=6e-34,
Organism=Homo sapiens, GI63252888, Length=187, Percent_Identity=40.1069518716578, Blast_Score=141, Evalue=6e-34,
Organism=Homo sapiens, GI63252886, Length=187, Percent_Identity=39.572192513369, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI63252893, Length=187, Percent_Identity=37.9679144385027, Blast_Score=134, Evalue=7e-32,
Organism=Homo sapiens, GI63252891, Length=187, Percent_Identity=37.9679144385027, Blast_Score=134, Evalue=7e-32,
Organism=Homo sapiens, GI217272861, Length=187, Percent_Identity=37.9679144385027, Blast_Score=134, Evalue=7e-32,
Organism=Homo sapiens, GI4758868, Length=187, Percent_Identity=36.8983957219251, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI217272863, Length=187, Percent_Identity=36.8983957219251, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI33589818, Length=202, Percent_Identity=38.1188118811881, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI217272851, Length=186, Percent_Identity=34.4086021505376, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17541712, Length=205, Percent_Identity=34.6341463414634, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17552840, Length=204, Percent_Identity=32.843137254902, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193209070, Length=139, Percent_Identity=30.2158273381295, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193209068, Length=136, Percent_Identity=30.8823529411765, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17550388, Length=228, Percent_Identity=25.4385964912281, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000637, Length=120, Percent_Identity=31.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651407, Length=187, Percent_Identity=35.8288770053476, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24651477, Length=186, Percent_Identity=37.0967741935484, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24651418, Length=185, Percent_Identity=36.2162162162162, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24651424, Length=184, Percent_Identity=34.2391304347826, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI116008432, Length=192, Percent_Identity=34.8958333333333, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281362877, Length=237, Percent_Identity=31.2236286919831, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI116008128, Length=192, Percent_Identity=34.8958333333333, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221460681, Length=190, Percent_Identity=33.1578947368421, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24651420, Length=188, Percent_Identity=35.6382978723404, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281361323, Length=191, Percent_Identity=31.413612565445, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI116008434, Length=213, Percent_Identity=29.5774647887324, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78706702, Length=220, Percent_Identity=27.7272727272727, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24651430, Length=188, Percent_Identity=28.7234042553192, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221512818, Length=128, Percent_Identity=39.0625, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21358233, Length=188, Percent_Identity=30.3191489361702, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI116008130, Length=206, Percent_Identity=28.6407766990291, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI116008537, Length=206, Percent_Identity=28.6407766990291, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24651416, Length=185, Percent_Identity=30.8108108108108, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358309, Length=185, Percent_Identity=30.8108108108108, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45550650, Length=181, Percent_Identity=25.414364640884, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI161076739, Length=210, Percent_Identity=27.6190476190476, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24666354, Length=191, Percent_Identity=30.3664921465969, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30802; Mature: 30671

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVDTRPAVGNPGYATSSPELERWLARHISEGFGAESLVLSMLRSGYDAAFARSAVATAM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
GHRRPDASATQPAPRLARREVPVLFSLQSPSIRLYQHLLSDAECDALVELARGRLARSPV
HCCCCCCCCCCCCHHHHHCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
INPDTGDENLIDARTSMGAMFQVGEHTLIQRIEDRIAAVLGVPVDHGEGLQILNYKPGGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
YQPHFDFFNPKRPGEARQLRVGGQRTATLVIYLNTPQAGGATAFPRIGLEVAPVKGNAVY
CCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEE
FSYLQPDGKLDERTLHAGLPVQSGEKWIATKWLREHPYRAGA
EEEECCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVDTRPAVGNPGYATSSPELERWLARHISEGFGAESLVLSMLRSGYDAAFARSAVATAM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
GHRRPDASATQPAPRLARREVPVLFSLQSPSIRLYQHLLSDAECDALVELARGRLARSPV
HCCCCCCCCCCCCHHHHHCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
INPDTGDENLIDARTSMGAMFQVGEHTLIQRIEDRIAAVLGVPVDHGEGLQILNYKPGGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
YQPHFDFFNPKRPGEARQLRVGGQRTATLVIYLNTPQAGGATAFPRIGLEVAPVKGNAVY
CCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEE
FSYLQPDGKLDERTLHAGLPVQSGEKWIATKWLREHPYRAGA
EEEECCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA