Click here to switch to the map view.

The map label for this gene is hpmB [H]

Identifier: 73542616

GI number: 73542616

Start: 3213201

End: 3214949

Strand: Reverse

Name: hpmB [H]

Synonym: Reut_A2932

Alternate gene names: 73542616

Gene position: 3214949-3213201 (Counterclockwise)

Preceding gene: 73542617

Following gene: 73542615

Centisome position: 84.46

GC content: 66.55

Gene sequence:

>1749_bases
ATGAGGAGGCGTGCTGACTCCTTGCGCGCCGCTGCGTCGGCGGCCGCCCTGGCCTGTACAACGACGTGGGCACAGGTGCC
GCCCGCCGCGCTCGTGCCGGAAGATCCCGCCCAGCGCTTGTTGCGCGAACAGCGCCAGCGGGAGCTCGAGCGAGAGGCGA
CCCAGCCCCCGGCGAGGATCGAACCGCCCGCCGTCGTGCCAGCCGATGCCCCGGTGGAATCGGTGCAGGAAACTTCGGCC
ACCTTCGATATCCAGCGCATCGAGGTCCTCGGCAACACCGTCTTGTCCGAGCGGGAGATCAAGGCCATCACTGCGCCGTT
CGTTGGCCATGCGCTCGGTACCAATCGCATCAACTTGCTGCTGCGCCGCTTCACGGAAGCGTTCGTGGCCAAGGGCTACA
TCACCACCCGCGCCTACCTGGGCGAGCAGAACCTGACCAGTGGCGTGCTCGTGGTGACGGTCGTGCCCGGAAAGGTCGAG
GCGGTTACGCTCAATGGCAGCGCCATCCGTCCCAACGAGCGCGCCCTGTTCGATACGGCTGGTGGCGGCTGGGTGACCGA
CGCCGGTACCGCTGGCCAGTTCCCCGCGCCGGGGGACACGTTGCGGCTGCAGGACCTGGAGCAGGGCGTGGACCAGATCA
ACCGGTTGCGCCGCAATCGTGCCGAGTTGCAGATTCAGCCCGGCCAGACACCGGGCAGCTCCATCGTTGCGCTTACCAAC
GCGCCTGCCGACCGCTTCCGCTTCAACGCGGGGGTGGACAACTACGGCAGCAAATCGACCGGCATCTCGCGAACACGCCT
TGGCATTGACGCCGATAACGCCCTGGGCTTTCAGGAGTCGCTCGCAGCCAGTTACGTTGGTACCCTGGATACGAATGCCG
CCGTCGTATCGGCGGCGGTGCCCTGGGGCTACAACACCTTCAGCTACACCGGCTCGGTTTCCGAGTACCAGAACGTCATC
GGCGACACCGCGCTGCTGTATGGCCGCACCTTCGGCCATACCGTTGGCTGGAACCGGGTACTCACGCGCAGCCAGAGCGG
CCGACAGGCCTTCGACCTGACGCTCACGCATCGCAAGACTGAGCGCGAGATCAACAATTTCGAGCTCGACCCGCAGCGGC
TGACGGTGCTGCGCGCCGCGTGGAGCGGGCTTCGGCGCTTCGCGGCCAACGGCCAGCCGGGATATGGCACGGCAGAGGTC
GGTCTCTCGCGCGGCCTGCCAAGCGTCAATGCGACGCGCGACCCCTCTGACATCCGGTCCGACGAAGCACATGCCCAGTT
CACGAAGCTCGACGCCAATGTGGGCTGGCAACTGCCATTGCCCGTGGTTCTCGACAGCGCTCGGCTGGCCTGGCGCAGTC
AGGTGGTCGGCCAGTGGACCAACGTGGCGCTGTTCGGCTCCGAGCAGATCTATGCCGGCGGCATGAGCACGGTGCGGGGC
TTTCGCGAAGGGGTTATTGCCGGCGATCGGGGTGCGTACTGGCGCAACGAATTGGCCTGGGCCAATGCCCCGACGCTGGC
TGGCCTGCGCATGGAACCGTACCTGTTTCTGGACGGGGGGCAGGCGATGTATGTCGCCAACCGTCATTGGCAATACGTGT
CCGGCACCGGCGCCGGCCTTCGCCTCTCGGCCCAATGGGCCCGACAGACCTTCACCAGTGAGCTGCTGGTCGGCATGCCG
CTGGCACAACCATCCGTGCTGGGCGCCAGGCGACCCATCGTGCTGGCCACGCTCAACTGGATGTACTAG

Upstream 100 bases:

>100_bases
GCAACGTTGCGGTCAGCGGCGTGACCACAATGACTCGTCCACGCCAGCGTGACCCCGTCACCATCGAGAATCACCTCGGC
CTCACTTCGTGGTTGTGGCG

Downstream 100 bases:

>100_bases
CCGCGATTTCCAAGGAATCACATATGCAAACCAATATTTCCCGCCTGATTGTCACCATTGCCTTGGCCTTCGGCCTGCAG
GCAGGCTTGTCCGTCGCCCA

Product: hemolysin activator HlyB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MRRRADSLRAAASAAALACTTTWAQVPPAALVPEDPAQRLLREQRQRELEREATQPPARIEPPAVVPADAPVESVQETSA
TFDIQRIEVLGNTVLSEREIKAITAPFVGHALGTNRINLLLRRFTEAFVAKGYITTRAYLGEQNLTSGVLVVTVVPGKVE
AVTLNGSAIRPNERALFDTAGGGWVTDAGTAGQFPAPGDTLRLQDLEQGVDQINRLRRNRAELQIQPGQTPGSSIVALTN
APADRFRFNAGVDNYGSKSTGISRTRLGIDADNALGFQESLAASYVGTLDTNAAVVSAAVPWGYNTFSYTGSVSEYQNVI
GDTALLYGRTFGHTVGWNRVLTRSQSGRQAFDLTLTHRKTEREINNFELDPQRLTVLRAAWSGLRRFAANGQPGYGTAEV
GLSRGLPSVNATRDPSDIRSDEAHAQFTKLDANVGWQLPLPVVLDSARLAWRSQVVGQWTNVALFGSEQIYAGGMSTVRG
FREGVIAGDRGAYWRNELAWANAPTLAGLRMEPYLFLDGGQAMYVANRHWQYVSGTGAGLRLSAQWARQTFTSELLVGMP
LAQPSVLGARRPIVLATLNWMY

Sequences:

>Translated_582_residues
MRRRADSLRAAASAAALACTTTWAQVPPAALVPEDPAQRLLREQRQRELEREATQPPARIEPPAVVPADAPVESVQETSA
TFDIQRIEVLGNTVLSEREIKAITAPFVGHALGTNRINLLLRRFTEAFVAKGYITTRAYLGEQNLTSGVLVVTVVPGKVE
AVTLNGSAIRPNERALFDTAGGGWVTDAGTAGQFPAPGDTLRLQDLEQGVDQINRLRRNRAELQIQPGQTPGSSIVALTN
APADRFRFNAGVDNYGSKSTGISRTRLGIDADNALGFQESLAASYVGTLDTNAAVVSAAVPWGYNTFSYTGSVSEYQNVI
GDTALLYGRTFGHTVGWNRVLTRSQSGRQAFDLTLTHRKTEREINNFELDPQRLTVLRAAWSGLRRFAANGQPGYGTAEV
GLSRGLPSVNATRDPSDIRSDEAHAQFTKLDANVGWQLPLPVVLDSARLAWRSQVVGQWTNVALFGSEQIYAGGMSTVRG
FREGVIAGDRGAYWRNELAWANAPTLAGLRMEPYLFLDGGQAMYVANRHWQYVSGTGAGLRLSAQWARQTFTSELLVGMP
LAQPSVLGARRPIVLATLNWMY
>Mature_582_residues
MRRRADSLRAAASAAALACTTTWAQVPPAALVPEDPAQRLLREQRQRELEREATQPPARIEPPAVVPADAPVESVQETSA
TFDIQRIEVLGNTVLSEREIKAITAPFVGHALGTNRINLLLRRFTEAFVAKGYITTRAYLGEQNLTSGVLVVTVVPGKVE
AVTLNGSAIRPNERALFDTAGGGWVTDAGTAGQFPAPGDTLRLQDLEQGVDQINRLRRNRAELQIQPGQTPGSSIVALTN
APADRFRFNAGVDNYGSKSTGISRTRLGIDADNALGFQESLAASYVGTLDTNAAVVSAAVPWGYNTFSYTGSVSEYQNVI
GDTALLYGRTFGHTVGWNRVLTRSQSGRQAFDLTLTHRKTEREINNFELDPQRLTVLRAAWSGLRRFAANGQPGYGTAEV
GLSRGLPSVNATRDPSDIRSDEAHAQFTKLDANVGWQLPLPVVLDSARLAWRSQVVGQWTNVALFGSEQIYAGGMSTVRG
FREGVIAGDRGAYWRNELAWANAPTLAGLRMEPYLFLDGGQAMYVANRHWQYVSGTGAGLRLSAQWARQTFTSELLVGMP
LAQPSVLGARRPIVLATLNWMY

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 63206; Mature: 63206

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRADSLRAAASAAALACTTTWAQVPPAALVPEDPAQRLLREQRQRELEREATQPPARI
CCCCHHHHHHHHHHHHHEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EPPAVVPADAPVESVQETSATFDIQRIEVLGNTVLSEREIKAITAPFVGHALGTNRINLL
CCCEECCCCCCHHHHHHHHHHEEHHHHHHHHHHHHCCCHHHEEECCHHHHHCCCHHHHHH
LRRFTEAFVAKGYITTRAYLGEQNLTSGVLVVTVVPGKVEAVTLNGSAIRPNERALFDTA
HHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEEECCCEEEEEECCCEECCCCCEEEECC
GGGWVTDAGTAGQFPAPGDTLRLQDLEQGVDQINRLRRNRAELQIQPGQTPGSSIVALTN
CCCEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEC
APADRFRFNAGVDNYGSKSTGISRTRLGIDADNALGFQESLAASYVGTLDTNAAVVSAAV
CCHHHEEEECCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEC
PWGYNTFSYTGSVSEYQNVIGDTALLYGRTFGHTVGWNRVLTRSQSGRQAFDLTLTHRKT
CCCCCCEEECCCHHHHHHHHCCHHEEECCCCCCCCCCHHHHHCCCCCCEEEEEEEECCHH
EREINNFELDPQRLTVLRAAWSGLRRFAANGQPGYGTAEVGLSRGLPSVNATRDPSDIRS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCC
DEAHAQFTKLDANVGWQLPLPVVLDSARLAWRSQVVGQWTNVALFGSEQIYAGGMSTVRG
CCHHHEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCEEEECCCEEEECCHHHHHH
FREGVIAGDRGAYWRNELAWANAPTLAGLRMEPYLFLDGGQAMYVANRHWQYVSGTGAGL
HHHCCEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEECCCEEEEECCCEEEEECCCCCE
RLSAQWARQTFTSELLVGMPLAQPSVLGARRPIVLATLNWMY
EEEHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEECCCC
>Mature Secondary Structure
MRRRADSLRAAASAAALACTTTWAQVPPAALVPEDPAQRLLREQRQRELEREATQPPARI
CCCCHHHHHHHHHHHHHEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EPPAVVPADAPVESVQETSATFDIQRIEVLGNTVLSEREIKAITAPFVGHALGTNRINLL
CCCEECCCCCCHHHHHHHHHHEEHHHHHHHHHHHHCCCHHHEEECCHHHHHCCCHHHHHH
LRRFTEAFVAKGYITTRAYLGEQNLTSGVLVVTVVPGKVEAVTLNGSAIRPNERALFDTA
HHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEEECCCEEEEEECCCEECCCCCEEEECC
GGGWVTDAGTAGQFPAPGDTLRLQDLEQGVDQINRLRRNRAELQIQPGQTPGSSIVALTN
CCCEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEC
APADRFRFNAGVDNYGSKSTGISRTRLGIDADNALGFQESLAASYVGTLDTNAAVVSAAV
CCHHHEEEECCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEC
PWGYNTFSYTGSVSEYQNVIGDTALLYGRTFGHTVGWNRVLTRSQSGRQAFDLTLTHRKT
CCCCCCEEECCCHHHHHHHHCCHHEEECCCCCCCCCCHHHHHCCCCCCEEEEEEEECCHH
EREINNFELDPQRLTVLRAAWSGLRRFAANGQPGYGTAEVGLSRGLPSVNATRDPSDIRS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCC
DEAHAQFTKLDANVGWQLPLPVVLDSARLAWRSQVVGQWTNVALFGSEQIYAGGMSTVRG
CCHHHEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCEEEECCCEEEECCHHHHHH
FREGVIAGDRGAYWRNELAWANAPTLAGLRMEPYLFLDGGQAMYVANRHWQYVSGTGAGL
HHHCCEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEECCCEEEEECCCEEEEECCCCCE
RLSAQWARQTFTSELLVGMPLAQPSVLGARRPIVLATLNWMY
EEEHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]