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The map label for this gene is corA [H]

Identifier: 73542538

GI number: 73542538

Start: 3126529

End: 3127491

Strand: Direct

Name: corA [H]

Synonym: Reut_A2853

Alternate gene names: 73542538

Gene position: 3126529-3127491 (Clockwise)

Preceding gene: 73542537

Following gene: 73542547

Centisome position: 82.14

GC content: 61.79

Gene sequence:

>963_bases
ATGATCAACCTGTTCGTCCTGCAGAAAGGCCGGCTCGCCCAAGAGCAGGTCGACGAGCGCAACGAGCTGCTGCAGCACAA
GCCGATCTGGATCGACGTCGTCAGCCCCGACGACGAGGAACTCGCCTGGATCAAGGAAGCGTACGGCGTCGCCCTGCCGG
AACTCGAAGACCTGGGCGACCTGGAAGCGTCCGCGCGTTATTTCGAAGGCGAGGACGAGAACATCCACATCCGCACCGAC
TTCCTGCTCGACGAGGAAGAGGCTTCGCGCAACGTGCGCGTGGCGTTCGTGCTCACGCGCGACGTGCTGTTTTCCATCCA
CGACGAAGACCTGCCGGTGTTCCGCCTGGTGCGGCTGCGCGCGCGCATGCGTCCGGGCTCGGTACGCAACGCCAAGGACG
TGCTGATGGATCTGTACGCGACCGATGCGGAATACTCGGCCGACTCCATCGAGGAAGTCTACGAACGCCTGGAAGAAGCC
AGCCGCCGCGTGCTGGCCGAAAACGTGACCGATGCCGCCGCCGCCGACGTGCTCGAAACCATCGCGCGCGAGGAAGACTT
GAACGGCCGCATCCGACGCAACGTCATGGACACGCGCCGCGCGGTGTCGTTCCTGATGCGCAGCCAGCTGCTGTCAGCCG
AGCAGCAGGACGAGGCACGCCAGATCCTGCGCGACATCGACTCGATCGAGAACCACACCGCATTCCTGTTCGACAAGATC
AACTTCCTGATGGATGCGACCGTCGGTTTCATCAACATCAACCAGAACAAGATCATCAAGCTGTTCTCGGTGGTGTCGGT
GGCATTGATGCCACCGACGCTGATCGCGAGTATCTACGGCATGAACTTCAAATTCATGCCGGAGCTGGACTGGGCGGCTG
GGTATCCGTGGGCGATTGCGTTGATGGCGGTGTCGGCGGCGATTCCGTTGGTGTATTTCAAGCGGAAGGGGTGGTTGAGC
TGA

Upstream 100 bases:

>100_bases
GGTCCGGACCACCCTGGGATGCGGCGAGCCTGCCTGCGCTTGTCTTCGCGCTTGTCTTTGTTTTTCGTCGCAATCAGCAT
AGCAATAAGGAATCCCGGGG

Downstream 100 bases:

>100_bases
GGGCCGAAACAACGACAGGCTGACTCCCCTCCCCCGCTCCTCTCCCGCAAGCGCGAGAGGAGAGAAGGAACGCCAGCCGT
CAATCCGGCAACGTAGCCGC

Product: magnesium/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MINLFVLQKGRLAQEQVDERNELLQHKPIWIDVVSPDDEELAWIKEAYGVALPELEDLGDLEASARYFEGEDENIHIRTD
FLLDEEEASRNVRVAFVLTRDVLFSIHDEDLPVFRLVRLRARMRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEEA
SRRVLAENVTDAAAADVLETIAREEDLNGRIRRNVMDTRRAVSFLMRSQLLSAEQQDEARQILRDIDSIENHTAFLFDKI
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKFMPELDWAAGYPWAIALMAVSAAIPLVYFKRKGWLS

Sequences:

>Translated_320_residues
MINLFVLQKGRLAQEQVDERNELLQHKPIWIDVVSPDDEELAWIKEAYGVALPELEDLGDLEASARYFEGEDENIHIRTD
FLLDEEEASRNVRVAFVLTRDVLFSIHDEDLPVFRLVRLRARMRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEEA
SRRVLAENVTDAAAADVLETIAREEDLNGRIRRNVMDTRRAVSFLMRSQLLSAEQQDEARQILRDIDSIENHTAFLFDKI
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKFMPELDWAAGYPWAIALMAVSAAIPLVYFKRKGWLS
>Mature_320_residues
MINLFVLQKGRLAQEQVDERNELLQHKPIWIDVVSPDDEELAWIKEAYGVALPELEDLGDLEASARYFEGEDENIHIRTD
FLLDEEEASRNVRVAFVLTRDVLFSIHDEDLPVFRLVRLRARMRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEEA
SRRVLAENVTDAAAADVLETIAREEDLNGRIRRNVMDTRRAVSFLMRSQLLSAEQQDEARQILRDIDSIENHTAFLFDKI
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKFMPELDWAAGYPWAIALMAVSAAIPLVYFKRKGWLS

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=320, Percent_Identity=45.625, Blast_Score=273, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36672; Mature: 36672

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLFVLQKGRLAQEQVDERNELLQHKPIWIDVVSPDDEELAWIKEAYGVALPELEDLGD
CEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHCC
LEASARYFEGEDENIHIRTDFLLDEEEASRNVRVAFVLTRDVLFSIHDEDLPVFRLVRLR
HHHHHHHCCCCCCEEEEEEEEEECHHHHCCCEEEEEEEEEHHHHHCCCCCCHHHHHHHHH
ARMRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEEASRRVLAENVTDAAAADVLET
HHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IAREEDLNGRIRRNVMDTRRAVSFLMRSQLLSAEQQDEARQILRDIDSIENHTAFLFDKI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKFMPELDWAAGYPWAIA
HHHHHCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCCCCCCHHHHH
LMAVSAAIPLVYFKRKGWLS
HHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure
MINLFVLQKGRLAQEQVDERNELLQHKPIWIDVVSPDDEELAWIKEAYGVALPELEDLGD
CEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHCC
LEASARYFEGEDENIHIRTDFLLDEEEASRNVRVAFVLTRDVLFSIHDEDLPVFRLVRLR
HHHHHHHCCCCCCEEEEEEEEEECHHHHCCCEEEEEEEEEHHHHHCCCCCCHHHHHHHHH
ARMRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEEASRRVLAENVTDAAAADVLET
HHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IAREEDLNGRIRRNVMDTRRAVSFLMRSQLLSAEQQDEARQILRDIDSIENHTAFLFDKI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKFMPELDWAAGYPWAIA
HHHHHCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCCCCCCHHHHH
LMAVSAAIPLVYFKRKGWLS
HHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA