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The map label for this gene is thiL [H]

Identifier: 73542533

GI number: 73542533

Start: 3121815

End: 3122795

Strand: Direct

Name: thiL [H]

Synonym: Reut_A2848

Alternate gene names: 73542533

Gene position: 3121815-3122795 (Clockwise)

Preceding gene: 73542529

Following gene: 73542534

Centisome position: 82.01

GC content: 67.79

Gene sequence:

>981_bases
ATGTCCACGATCCGCCGCGCGCAGCTCTCCGAGTTCGATCTGATCCGCCGTTTCTTTACGCGTCCGGTACGCAAGGCCGT
GCTTGGCGTGGGCGACGACTGCGCGCTGATCGATCCGCGGCCCGGCCATCACCTGGCCATCAGCACCGACATGCTGGTCA
GCGGGCGCCATTTCTTTGCCGATGTCCCGCCCCGTGCACTGGGCCATAAGGCGCTGGCGGTCAACTTGTCAGATCTGGCG
GCCATGGGCGCCGAGCCGCGCGGGTTCACGCTCGCGCTGGCACTGCCCGAAGCCGATCCCGCATGGCTTGAAGAACTGGC
TGCAGGCATGTTGGCGCTCGCCGACGAACACGGCTGCGAGCTGATCGGCGGCGACACCACACGCGGGCCGCTCACGCTTA
GCCTGACCGTATTCGGCGACGTGCCGGCGCGCGCCGCCCTGCGACGCGATGCCGCGCGTCCTGGCGACGATATCTGGGTT
TCCGGAACACTTGGCGACGCGCGTCTCGCACTGGGCGACTGCCGCGGCGAATGGCTGTTGCCCGAACCCGAATTCAGCCG
CGTGCGCCCGCGTATGGAAATGCCGACGCCGCGCGTCGCGCTGGGCATGGCGCTGCGCGGTGTAGCGCATGCGGCACTTG
ATATTTCAGATGGCCTGATCGGCGATCTCGGCCACATCCTGACCCGCTCGCAGGTCGGGGCACTGCTCGACGTGGACTCG
CTGCCGCGTTCAACCGTGCTGGCGGCCCAACCGGACTCGCTGCAACGCGAATGCGTGCTGGCCGGCGGCGACGACTACGA
ACTTTGCTTCACCGCGCCGATCGGCAACCGTGAAGCCATTGCCGCCATCTCGGATCGCCTGGAACTGCCGCTGACACGCG
TCGGCTCGATCACACCGGAACCCGGCTTGCGGCTGGTCGACCGCCATGGCAGCCCCGTGACCTATGCCGGCGCTAGCTTC
GACCACTTCGCGTCGCCCTGA

Upstream 100 bases:

>100_bases
CTGCCGCCCGCTGCAGTATCTTGCCGAGCCGCTGGCCTGGCACCATCCTTGTCCCGATCCGCCTTTTTTGCGCCGGCGCC
GCCCTGGCCCGGTTAGTCCC

Downstream 100 bases:

>100_bases
CAGCCTGCGCGCGGGCGTGTCATGATGCCGGCTTGCAGCGCCAGCATCATGATCTGCCCGGGAGGGAACCCGGGAAACTG
GCACGCCGGGCGCCGCGCAC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSTIRRAQLSEFDLIRRFFTRPVRKAVLGVGDDCALIDPRPGHHLAISTDMLVSGRHFFADVPPRALGHKALAVNLSDLA
AMGAEPRGFTLALALPEADPAWLEELAAGMLALADEHGCELIGGDTTRGPLTLSLTVFGDVPARAALRRDAARPGDDIWV
SGTLGDARLALGDCRGEWLLPEPEFSRVRPRMEMPTPRVALGMALRGVAHAALDISDGLIGDLGHILTRSQVGALLDVDS
LPRSTVLAAQPDSLQRECVLAGGDDYELCFTAPIGNREAIAAISDRLELPLTRVGSITPEPGLRLVDRHGSPVTYAGASF
DHFASP

Sequences:

>Translated_326_residues
MSTIRRAQLSEFDLIRRFFTRPVRKAVLGVGDDCALIDPRPGHHLAISTDMLVSGRHFFADVPPRALGHKALAVNLSDLA
AMGAEPRGFTLALALPEADPAWLEELAAGMLALADEHGCELIGGDTTRGPLTLSLTVFGDVPARAALRRDAARPGDDIWV
SGTLGDARLALGDCRGEWLLPEPEFSRVRPRMEMPTPRVALGMALRGVAHAALDISDGLIGDLGHILTRSQVGALLDVDS
LPRSTVLAAQPDSLQRECVLAGGDDYELCFTAPIGNREAIAAISDRLELPLTRVGSITPEPGLRLVDRHGSPVTYAGASF
DHFASP
>Mature_325_residues
STIRRAQLSEFDLIRRFFTRPVRKAVLGVGDDCALIDPRPGHHLAISTDMLVSGRHFFADVPPRALGHKALAVNLSDLAA
MGAEPRGFTLALALPEADPAWLEELAAGMLALADEHGCELIGGDTTRGPLTLSLTVFGDVPARAALRRDAARPGDDIWVS
GTLGDARLALGDCRGEWLLPEPEFSRVRPRMEMPTPRVALGMALRGVAHAALDISDGLIGDLGHILTRSQVGALLDVDSL
PRSTVLAAQPDSLQRECVLAGGDDYELCFTAPIGNREAIAAISDRLELPLTRVGSITPEPGLRLVDRHGSPVTYAGASFD
HFASP

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=324, Percent_Identity=46.2962962962963, Blast_Score=249, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34763; Mature: 34632

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIRRAQLSEFDLIRRFFTRPVRKAVLGVGDDCALIDPRPGHHLAISTDMLVSGRHFFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEECCEEECCCCEEE
DVPPRALGHKALAVNLSDLAAMGAEPRGFTLALALPEADPAWLEELAAGMLALADEHGCE
CCCHHHHCCEEEEEEHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCE
LIGGDTTRGPLTLSLTVFGDVPARAALRRDAARPGDDIWVSGTLGDARLALGDCRGEWLL
EECCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCCC
PEPEFSRVRPRMEMPTPRVALGMALRGVAHAALDISDGLIGDLGHILTRSQVGALLDVDS
CCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCEEECCC
LPRSTVLAAQPDSLQRECVLAGGDDYELCFTAPIGNREAIAAISDRLELPLTRVGSITPE
CCCCEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCC
PGLRLVDRHGSPVTYAGASFDHFASP
CCCEEEECCCCCEEECCCCCHHCCCC
>Mature Secondary Structure 
STIRRAQLSEFDLIRRFFTRPVRKAVLGVGDDCALIDPRPGHHLAISTDMLVSGRHFFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEECCEEECCCCEEE
DVPPRALGHKALAVNLSDLAAMGAEPRGFTLALALPEADPAWLEELAAGMLALADEHGCE
CCCHHHHCCEEEEEEHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCE
LIGGDTTRGPLTLSLTVFGDVPARAALRRDAARPGDDIWVSGTLGDARLALGDCRGEWLL
EECCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCCC
PEPEFSRVRPRMEMPTPRVALGMALRGVAHAALDISDGLIGDLGHILTRSQVGALLDVDS
CCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCEEECCC
LPRSTVLAAQPDSLQRECVLAGGDDYELCFTAPIGNREAIAAISDRLELPLTRVGSITPE
CCCCEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCC
PGLRLVDRHGSPVTYAGASFDHFASP
CCCEEEECCCCCEEECCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]