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The map label for this gene is hda [H]

Identifier: 73542460

GI number: 73542460

Start: 3044368

End: 3045075

Strand: Direct

Name: hda [H]

Synonym: Reut_A2775

Alternate gene names: 73542460

Gene position: 3044368-3045075 (Clockwise)

Preceding gene: 73542459

Following gene: 73542461

Centisome position: 79.98

GC content: 65.68

Gene sequence:

>708_bases
ATGTCCCCGCGTCCCAAGCAACTTTCGCTCGAGCTTGGCAGCCCCCCGCCTTCGACCTTCGACAATTTTGTCGTGGCTTC
GAACCGCGAGGCGGTGCAACGCCTGCACGACCTGCCCAGTGCGGTCGCGCAGGAGCGCGCCATTGACCGGCTGTTCTATC
TGTGGGGGGAAAACGGCTGCGGCCGCACGCACCTGCTGCATGCGGTGTGCGAGGCGACGCCCCAAACCGGCATCAACTGC
CGCTACCTGAGCCCGCACCACCCGCTGTCCGATTTCCTGTTCGACCCGTCCTGCCAGCTTTATACGGTCGATGACGTCGA
ACTGCTCGATGAAGCGCGGCAGATCGCGGTGTTTTCGCTGTACAACGAAGTCCGCGCGCACGTGCGCACCGCGCTGGTCG
TGGCAGGGGGCATGGCACCGCGCGCCATGCCCGTGCGCGAAGACCTGCGCACCCGGCTCGGCTGGGGATTGGTCTACCAG
GTCCAGCCGCTGTCGGACGAGGACAAGATGTCCGCAGTGCTTCAGGCGGCACGCGAGCGGGGCCTGCAGCTGTCCCCGGA
AATCACGCACTGGCTGGTCACGCGCCATTACCGCGACATGCCCAGCCTGATGGCGCTGCTCGATGCGCTGGATACCTACT
CGCTGGAGCGCAAGCGCCCGGTCACCCTGCCCCTGCTTCGCGAAATGTTCGCGGAGTTTCGGGAATAA

Upstream 100 bases:

>100_bases
GGAAATAACGGAAGCGACGGGAAAAATGACGGACAATAGTCGGCTTGAGCCGATTCCATGTGCACCGCGCAAGCTGTCCC
CCGCAAGTTAGCCATACGTC

Downstream 100 bases:

>100_bases
TCGCCGGAAATCTTCGCCACCCGCCTTTTTGTGGCCGGCGCGAGAGCACGCGGACCGGCACACTCGCTTAAGGTAAAATC
GCGCCCCATGAATCTGGCAC

Product: DnaA regulatory inactivator Hda

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSPRPKQLSLELGSPPPSTFDNFVVASNREAVQRLHDLPSAVAQERAIDRLFYLWGENGCGRTHLLHAVCEATPQTGINC
RYLSPHHPLSDFLFDPSCQLYTVDDVELLDEARQIAVFSLYNEVRAHVRTALVVAGGMAPRAMPVREDLRTRLGWGLVYQ
VQPLSDEDKMSAVLQAARERGLQLSPEITHWLVTRHYRDMPSLMALLDALDTYSLERKRPVTLPLLREMFAEFRE

Sequences:

>Translated_235_residues
MSPRPKQLSLELGSPPPSTFDNFVVASNREAVQRLHDLPSAVAQERAIDRLFYLWGENGCGRTHLLHAVCEATPQTGINC
RYLSPHHPLSDFLFDPSCQLYTVDDVELLDEARQIAVFSLYNEVRAHVRTALVVAGGMAPRAMPVREDLRTRLGWGLVYQ
VQPLSDEDKMSAVLQAARERGLQLSPEITHWLVTRHYRDMPSLMALLDALDTYSLERKRPVTLPLLREMFAEFRE
>Mature_234_residues
SPRPKQLSLELGSPPPSTFDNFVVASNREAVQRLHDLPSAVAQERAIDRLFYLWGENGCGRTHLLHAVCEATPQTGINCR
YLSPHHPLSDFLFDPSCQLYTVDDVELLDEARQIAVFSLYNEVRAHVRTALVVAGGMAPRAMPVREDLRTRLGWGLVYQV
QPLSDEDKMSAVLQAARERGLQLSPEITHWLVTRHYRDMPSLMALLDALDTYSLERKRPVTLPLLREMFAEFRE

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=237, Percent_Identity=35.0210970464135, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 26707; Mature: 26576

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRPKQLSLELGSPPPSTFDNFVVASNREAVQRLHDLPSAVAQERAIDRLFYLWGENGC
CCCCCCEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GRTHLLHAVCEATPQTGINCRYLSPHHPLSDFLFDPSCQLYTVDDVELLDEARQIAVFSL
CHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHH
YNEVRAHVRTALVVAGGMAPRAMPVREDLRTRLGWGLVYQVQPLSDEDKMSAVLQAARER
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHC
GLQLSPEITHWLVTRHYRDMPSLMALLDALDTYSLERKRPVTLPLLREMFAEFRE
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SPRPKQLSLELGSPPPSTFDNFVVASNREAVQRLHDLPSAVAQERAIDRLFYLWGENGC
CCCCCEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GRTHLLHAVCEATPQTGINCRYLSPHHPLSDFLFDPSCQLYTVDDVELLDEARQIAVFSL
CHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHH
YNEVRAHVRTALVVAGGMAPRAMPVREDLRTRLGWGLVYQVQPLSDEDKMSAVLQAARER
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHC
GLQLSPEITHWLVTRHYRDMPSLMALLDALDTYSLERKRPVTLPLLREMFAEFRE
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA