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The map label for this gene is ttuB [H]

Identifier: 73542302

GI number: 73542302

Start: 2867793

End: 2869103

Strand: Direct

Name: ttuB [H]

Synonym: Reut_A2617

Alternate gene names: 73542302

Gene position: 2867793-2869103 (Clockwise)

Preceding gene: 73542301

Following gene: 73542303

Centisome position: 75.34

GC content: 64.61

Gene sequence:

>1311_bases
ATGACAACGACTGCAGTGAATCCCGGCGTTGGCGACGCCGCGTTTGAAGACGCCACTTACCGCAAGGTGAGCTGGCGCCT
GGTGCCTTTCCTGCTGCTGTGCTACGTGGTGGCCTACCTGGACCGCGTCAACGTGGGCTTTGCCAAGCTGCAGATGCTCA
GCGACCTGAAGTTCAGCGAGACCATCTACGGCCTCGGCGCGGGGATCTTCTTCATCGGCTACTTCCTGTTCGAAGTGCCG
AGCAACGTGATCCTGCACAAGGTCGGCGCCCGCATCTGGATCGCGCGCATCATGATCACGTGGGGCGTCATTTCGGCGGC
GATGATGTTCGTCACCACGCCGACGATGTTCTACGTGCTGCGCTTCCTGCTCGGCATTGCGGAGGCCGGCTTCTTCCCCG
GCATCATCCTGTACCTGACCTACTGGTATCCGGCCAACCGGCGCGGGCGCACCACCACGTTCTTCATGACCGCCATCGCG
CTGTCGGGCGTGATCGGCGGCCCGCTGTCGGGCTGGGTGATGCAATCGTTCGACGGCCACAACGGCTGGTCCGGCTGGCA
GTGGATGTTCCTGCTCGAAGGCATCCCTTCGATCCTGGTCGGCCTGTGGGTGCTGGCCTACCTGGATGATCGTATCGTGC
ACGCCAAGTGGCTGACCAACGAGGAAAAGGCGCTGCTCGAACGCAATATCGCCCACGAAGACGCCCACAAGGAAGACCCG
CCGATCCGCACCGTGCTGTCCAGCCCGCGTGTGTGGCTGATGAGTGCGATCTACTTCTGCTTCGTGATGGGCCTCTACGG
CGTGAGCTTCTGGCTGCCGACCATCATCAAGCAGACCGGCGTCAAGAGCGCGCTCGACATCGGCCTGCTGACCGCGATCC
CGTATGGCTGCGCGGTGGTCGGCATGGTGCTGTTTGCGTTCAGCGCCGACCGTTCCGGCGAACGCCGCTGGCACATTGCC
ATTCCCGCCGTGGCGGGCGCGCTCGGCCTGCTGCTTTCGGTGTACTGGCATGACAGCACCGCGCTGGCCATGGTGGCGCT
GACGCTGGCGACGATCGGCATCCTGACCACGCTGCCGCTGTTCTGGAGCCTGCCTACCGCCTTCCTGGCCGGTACCGGCG
CTGCCGCCGGCATCGCGCTGATCAACTCGCTCGGCAACCTGGCCGGCTTCCTCAGCCCGTATGCGGTCGGCTGGCTCAAG
GACCTGACCCATACCACCGATTCCGGCATGTACCTGCTCGCGGCCTGCCTGGTGGTCGGCGCCGCGCTAACGCTGTCGGT
GCCGGCACGGCTGGTAAGCAGCAAGACCTGA

Upstream 100 bases:

>100_bases
CTAGCCAATACCGTTTTTGTGTAGCTGTATCTGCATCACCGAAGCGTCGTACCAACGTCATAGAAGCGTCGTAGAAGCGC
AACCATTCTGAGGAGACAGC

Downstream 100 bases:

>100_bases
CCTTCGTTCCCCTTGCACGCCGCAAACTGCCGCGGCGTGCACCTGCCAGGTGGCCTGCGCGCCGCCCGCATCCTGCAACA
CGCCCTCCTCCGACACGCAT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTTTAVNPGVGDAAFEDATYRKVSWRLVPFLLLCYVVAYLDRVNVGFAKLQMLSDLKFSETIYGLGAGIFFIGYFLFEVP
SNVILHKVGARIWIARIMITWGVISAAMMFVTTPTMFYVLRFLLGIAEAGFFPGIILYLTYWYPANRRGRTTTFFMTAIA
LSGVIGGPLSGWVMQSFDGHNGWSGWQWMFLLEGIPSILVGLWVLAYLDDRIVHAKWLTNEEKALLERNIAHEDAHKEDP
PIRTVLSSPRVWLMSAIYFCFVMGLYGVSFWLPTIIKQTGVKSALDIGLLTAIPYGCAVVGMVLFAFSADRSGERRWHIA
IPAVAGALGLLLSVYWHDSTALAMVALTLATIGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLK
DLTHTTDSGMYLLAACLVVGAALTLSVPARLVSSKT

Sequences:

>Translated_436_residues
MTTTAVNPGVGDAAFEDATYRKVSWRLVPFLLLCYVVAYLDRVNVGFAKLQMLSDLKFSETIYGLGAGIFFIGYFLFEVP
SNVILHKVGARIWIARIMITWGVISAAMMFVTTPTMFYVLRFLLGIAEAGFFPGIILYLTYWYPANRRGRTTTFFMTAIA
LSGVIGGPLSGWVMQSFDGHNGWSGWQWMFLLEGIPSILVGLWVLAYLDDRIVHAKWLTNEEKALLERNIAHEDAHKEDP
PIRTVLSSPRVWLMSAIYFCFVMGLYGVSFWLPTIIKQTGVKSALDIGLLTAIPYGCAVVGMVLFAFSADRSGERRWHIA
IPAVAGALGLLLSVYWHDSTALAMVALTLATIGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLK
DLTHTTDSGMYLLAACLVVGAALTLSVPARLVSSKT
>Mature_435_residues
TTTAVNPGVGDAAFEDATYRKVSWRLVPFLLLCYVVAYLDRVNVGFAKLQMLSDLKFSETIYGLGAGIFFIGYFLFEVPS
NVILHKVGARIWIARIMITWGVISAAMMFVTTPTMFYVLRFLLGIAEAGFFPGIILYLTYWYPANRRGRTTTFFMTAIAL
SGVIGGPLSGWVMQSFDGHNGWSGWQWMFLLEGIPSILVGLWVLAYLDDRIVHAKWLTNEEKALLERNIAHEDAHKEDPP
IRTVLSSPRVWLMSAIYFCFVMGLYGVSFWLPTIIKQTGVKSALDIGLLTAIPYGCAVVGMVLFAFSADRSGERRWHIAI
PAVAGALGLLLSVYWHDSTALAMVALTLATIGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKD
LTHTTDSGMYLLAACLVVGAALTLSVPARLVSSKT

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=424, Percent_Identity=36.7924528301887, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1789515, Length=426, Percent_Identity=23.4741784037559, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367379, Length=448, Percent_Identity=22.9910714285714, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789152, Length=414, Percent_Identity=23.9130434782609, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082320, Length=414, Percent_Identity=22.2222222222222, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537329, Length=284, Percent_Identity=25.3521126760563, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=190, Percent_Identity=28.9473684210526, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=321, Percent_Identity=24.6105919003115, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321698, Length=315, Percent_Identity=25.0793650793651, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6324410, Length=162, Percent_Identity=26.5432098765432, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=415, Percent_Identity=20.4819277108434, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321502, Length=368, Percent_Identity=21.195652173913, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=210, Percent_Identity=25.2380952380952, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=318, Percent_Identity=23.8993710691824, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584153, Length=362, Percent_Identity=23.7569060773481, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24583789, Length=363, Percent_Identity=22.5895316804408, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653727, Length=411, Percent_Identity=21.654501216545, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47652; Mature: 47520

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTTAVNPGVGDAAFEDATYRKVSWRLVPFLLLCYVVAYLDRVNVGFAKLQMLSDLKFSE
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHH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HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]