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The map label for this gene is citZ [H]

Identifier: 73541449

GI number: 73541449

Start: 1916636

End: 1917760

Strand: Reverse

Name: citZ [H]

Synonym: Reut_A1760

Alternate gene names: 73541449

Gene position: 1917760-1916636 (Counterclockwise)

Preceding gene: 73541454

Following gene: 73541448

Centisome position: 50.38

GC content: 66.22

Gene sequence:

>1125_bases
ATGGACGAGGCATGCGCGCGGCTCGGCGTGAGGCCGCAGACGGTCTACGCGTACGTCAGCCGCGGCAAGATCGAGGTCAT
GTCCGATCCGGTCGATACGCGTCGCAGCCTGTATCGCGCCGAAGACGTGGCGACGCTGGCCAAACGCAAGCAGGCTGGCC
GCAAGCATGAGACGCTGGCCACCAACACGCTGTTTGGCGCCGAGCCCAGCATTCCGACCGCGATCTCAACGTTCCTGCGC
GAACGGCTCTACTACCGTGGCCGCGACGCGGTGGTGCTCGCCGAAACCGCCACGCTGGAAGAGGCCGCGCAGTTGCTGTG
GGATTCAGCGCAGCCCGTGAATTTTTCGTCGTCCACCAAGGTGGCAAAACCGGGGCGTGTGGCGGCCTTCAAGGCGTTGG
CCGAACTGGCTGCCACCGGTCATTCGACACATGGCCGCATGACGCGCGTCCTGCATGCGGAAGGCCAGGGCCTGGTCGGC
CAGATGGCCAACGCGTTTGGCGCACAGCCGGGGCAGCAAGCGCTGCATATGCGCTTCGCGCAAGGGTGGGGGCTGAAGCC
GGCAGGGGCCGAGTTGCTGAGGATGGCCATGGTGCTGCTGGTCGATCATGAACTGACCAGCTCCGCGTTTGCGTCGCGTA
TCGCGGCGTCGAACGGTGCGTCGTTGCCGGCGTGCCTGCTTTCCGGCCTCGCTACCTTGTCCGGGCCGCTGCACGGTGAT
GCTTCCGGTCGCGTCAAGGCGCTGTTCAACGACGTCGAACGGCAGGGCGAAGATCAGGTCATCACGCACTACCTGTCGAC
AGGACAGGCGCTTGCGGGCTTCGGACACCACCTCTATCCCGAGGGCGACCCACGCGCCGCCGCGCTGCTGTCACGGTTCG
AGCCACCGCCGGTCATCGCCCGGTTCATCGCACAGGCAACACGCCTGACCGGCTTGCAGCCCAATATCGACGTGGCATTG
GCCGCGCTGGTGATTCACTGCGGCCTGCCCGACGATGCAGCATTCGGGATGTTCGCCACGGCGCGCAGCATCGGACTGCT
CGCGCATAGCCTGGAGCAACTGGGTGTGGGACAGGTGATCCGTCCGAGAGGCCGCTATGTCGGCGTGGTGCCGGAACGGG
TCTGA

Upstream 100 bases:

>100_bases
AGGACCCATGGTAGTTAATAGTTGATTGTCAATGCAATATTGATATATAAAATCAACATAAATAGATGTGGAGCAAATCA
CCATGGGTCCCTGGATATCG

Downstream 100 bases:

>100_bases
GCTACGCAAGTTTGCTGTGCGTGCTCTTGTACGAATGGGCAGACAGGCATGCGGCCCATTGCACTCTGCTTTATCACAGA
TATAAAACACGCTCAGCAGC

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MDEACARLGVRPQTVYAYVSRGKIEVMSDPVDTRRSLYRAEDVATLAKRKQAGRKHETLATNTLFGAEPSIPTAISTFLR
ERLYYRGRDAVVLAETATLEEAAQLLWDSAQPVNFSSSTKVAKPGRVAAFKALAELAATGHSTHGRMTRVLHAEGQGLVG
QMANAFGAQPGQQALHMRFAQGWGLKPAGAELLRMAMVLLVDHELTSSAFASRIAASNGASLPACLLSGLATLSGPLHGD
ASGRVKALFNDVERQGEDQVITHYLSTGQALAGFGHHLYPEGDPRAAALLSRFEPPPVIARFIAQATRLTGLQPNIDVAL
AALVIHCGLPDDAAFGMFATARSIGLLAHSLEQLGVGQVIRPRGRYVGVVPERV

Sequences:

>Translated_374_residues
MDEACARLGVRPQTVYAYVSRGKIEVMSDPVDTRRSLYRAEDVATLAKRKQAGRKHETLATNTLFGAEPSIPTAISTFLR
ERLYYRGRDAVVLAETATLEEAAQLLWDSAQPVNFSSSTKVAKPGRVAAFKALAELAATGHSTHGRMTRVLHAEGQGLVG
QMANAFGAQPGQQALHMRFAQGWGLKPAGAELLRMAMVLLVDHELTSSAFASRIAASNGASLPACLLSGLATLSGPLHGD
ASGRVKALFNDVERQGEDQVITHYLSTGQALAGFGHHLYPEGDPRAAALLSRFEPPPVIARFIAQATRLTGLQPNIDVAL
AALVIHCGLPDDAAFGMFATARSIGLLAHSLEQLGVGQVIRPRGRYVGVVPERV
>Mature_374_residues
MDEACARLGVRPQTVYAYVSRGKIEVMSDPVDTRRSLYRAEDVATLAKRKQAGRKHETLATNTLFGAEPSIPTAISTFLR
ERLYYRGRDAVVLAETATLEEAAQLLWDSAQPVNFSSSTKVAKPGRVAAFKALAELAATGHSTHGRMTRVLHAEGQGLVG
QMANAFGAQPGQQALHMRFAQGWGLKPAGAELLRMAMVLLVDHELTSSAFASRIAASNGASLPACLLSGLATLSGPLHGD
ASGRVKALFNDVERQGEDQVITHYLSTGQALAGFGHHLYPEGDPRAAALLSRFEPPPVIARFIAQATRLTGLQPNIDVAL
AALVIHCGLPDDAAFGMFATARSIGLLAHSLEQLGVGQVIRPRGRYVGVVPERV

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786527, Length=198, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 39887; Mature: 39887

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEACARLGVRPQTVYAYVSRGKIEVMSDPVDTRRSLYRAEDVATLAKRKQAGRKHETLA
CCCHHHHCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TNTLFGAEPSIPTAISTFLRERLYYRGRDAVVLAETATLEEAAQLLWDSAQPVNFSSSTK
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCC
VAKPGRVAAFKALAELAATGHSTHGRMTRVLHAEGQGLVGQMANAFGAQPGQQALHMRFA
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
QGWGLKPAGAELLRMAMVLLVDHELTSSAFASRIAASNGASLPACLLSGLATLSGPLHGD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
ASGRVKALFNDVERQGEDQVITHYLSTGQALAGFGHHLYPEGDPRAAALLSRFEPPPVIA
CCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHH
RFIAQATRLTGLQPNIDVALAALVIHCGLPDDAAFGMFATARSIGLLAHSLEQLGVGQVI
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
RPRGRYVGVVPERV
CCCCCEEECCCCCC
>Mature Secondary Structure
MDEACARLGVRPQTVYAYVSRGKIEVMSDPVDTRRSLYRAEDVATLAKRKQAGRKHETLA
CCCHHHHCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TNTLFGAEPSIPTAISTFLRERLYYRGRDAVVLAETATLEEAAQLLWDSAQPVNFSSSTK
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCC
VAKPGRVAAFKALAELAATGHSTHGRMTRVLHAEGQGLVGQMANAFGAQPGQQALHMRFA
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
QGWGLKPAGAELLRMAMVLLVDHELTSSAFASRIAASNGASLPACLLSGLATLSGPLHGD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
ASGRVKALFNDVERQGEDQVITHYLSTGQALAGFGHHLYPEGDPRAAALLSRFEPPPVIA
CCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHH
RFIAQATRLTGLQPNIDVALAALVIHCGLPDDAAFGMFATARSIGLLAHSLEQLGVGQVI
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
RPRGRYVGVVPERV
CCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006016; 12397186 [H]