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The map label for this gene is yybE [H]

Identifier: 73541346

GI number: 73541346

Start: 1786106

End: 1787071

Strand: Reverse

Name: yybE [H]

Synonym: Reut_A1656

Alternate gene names: 73541346

Gene position: 1787071-1786106 (Counterclockwise)

Preceding gene: 73541349

Following gene: 73541345

Centisome position: 46.95

GC content: 65.53

Gene sequence:

>966_bases
ATGGACAGGCTGTCCCTATCGTCACTGTCAGCGTCAGTCCCCATGTCCTCCTATCGGATCCTTCAGGAAACCGCCGTTCG
CTACTTCCTCGAAGTGGTACGCACCGGCTCGGTCAAGGATGCCGCGCTCAAGCTCAACGTGGCGCCGTCAGCGGTCAGCC
GGCAGATTGCCAAGCTCGAAAGCGAGCTGGACACCCTGCTGTTCGACCGACGAGCGCGGGGTCTGGTCCCCAATGCCGCG
GGCGAGTTGCTGGCCGCGTTCGCGAAGCGGTCGCTGCAGGACATCGAACGCGTCACGGGTGACATCCAGGCACTGCGGGG
TCTGCGCGCAGGACGAGTGCGGCTGGCCAGCGTCGAGGGCATCGCGCACGAATTTCTTCCCACCCTGGCGGCAAGGTTCA
GGGAGCAGCACACGGGCATTCGATTCGATCTGGATGTCTGCCTGCAGGGCGATGTCGCGCGGCGGATCCGCGACGGCGAG
GCCGATATCGGGGTCACGCTGAGCGGACTGCCTGAACGGGAGATCGAGGTGGAACTTCGCCACCCTGCCCCCGTACTGGC
GATCATGGCGCCCGACCACCCGCTCGCGGGGCAACGCCAGGTTTCGCTGTCGCAAGTCATTGCCTATCCGCTCGCCTTGC
CGCCGAAGGGCAGCTCGCTGCGGCAGCTGCTTGATACGAGCTGCAGCCGCCAGGACCTGCACTACCAGACGGTGTTCTCG
AGCAATCATCTCGACGCGCTCGTAAGCTTCGTGGTGGCAGGCGGCGGCGCCATCAGCTTCTACGGGGAGTTGTCGATACG
CGGGCGCCTGGAGTCCGGCACGATCGCCGCCGTGCCGTTGCGCGACCGGGAAATGAACGAGCGCTACATCGAGATCCAAA
CGCTGGCCAAGCGCAGCTTGCCCCCTGCGGCGCGCGCCTTCGTGCAGCAGTTGGTGCAGACCATTACCGGTGTCGGCACC
GCTTGA

Upstream 100 bases:

>100_bases
TGCAGTGGCGCCATGCCGTGTGTCACTATCCTACGGTCTCGCCAGCCTGAATTCGTGGCAATGTTTAGAACAATTGATTG
CCGTTTCGGCAATCCGTAGA

Downstream 100 bases:

>100_bases
TTGCCGAAATTGCAATCCATGGTTCTGTTAAATGCTGCGCAGGCATATTTCCTTCGGTTCGCGCGACACGGAGAATCTGA
AGCGGATCTGATCAGGCATG

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDRLSLSSLSASVPMSSYRILQETAVRYFLEVVRTGSVKDAALKLNVAPSAVSRQIAKLESELDTLLFDRRARGLVPNAA
GELLAAFAKRSLQDIERVTGDIQALRGLRAGRVRLASVEGIAHEFLPTLAARFREQHTGIRFDLDVCLQGDVARRIRDGE
ADIGVTLSGLPEREIEVELRHPAPVLAIMAPDHPLAGQRQVSLSQVIAYPLALPPKGSSLRQLLDTSCSRQDLHYQTVFS
SNHLDALVSFVVAGGGAISFYGELSIRGRLESGTIAAVPLRDREMNERYIEIQTLAKRSLPPAARAFVQQLVQTITGVGT
A

Sequences:

>Translated_321_residues
MDRLSLSSLSASVPMSSYRILQETAVRYFLEVVRTGSVKDAALKLNVAPSAVSRQIAKLESELDTLLFDRRARGLVPNAA
GELLAAFAKRSLQDIERVTGDIQALRGLRAGRVRLASVEGIAHEFLPTLAARFREQHTGIRFDLDVCLQGDVARRIRDGE
ADIGVTLSGLPEREIEVELRHPAPVLAIMAPDHPLAGQRQVSLSQVIAYPLALPPKGSSLRQLLDTSCSRQDLHYQTVFS
SNHLDALVSFVVAGGGAISFYGELSIRGRLESGTIAAVPLRDREMNERYIEIQTLAKRSLPPAARAFVQQLVQTITGVGT
A
>Mature_321_residues
MDRLSLSSLSASVPMSSYRILQETAVRYFLEVVRTGSVKDAALKLNVAPSAVSRQIAKLESELDTLLFDRRARGLVPNAA
GELLAAFAKRSLQDIERVTGDIQALRGLRAGRVRLASVEGIAHEFLPTLAARFREQHTGIRFDLDVCLQGDVARRIRDGE
ADIGVTLSGLPEREIEVELRHPAPVLAIMAPDHPLAGQRQVSLSQVIAYPLALPPKGSSLRQLLDTSCSRQDLHYQTVFS
SNHLDALVSFVVAGGGAISFYGELSIRGRLESGTIAAVPLRDREMNERYIEIQTLAKRSLPPAARAFVQQLVQTITGVGT
A

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=226, Percent_Identity=29.2035398230088, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787601, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788481, Length=254, Percent_Identity=29.9212598425197, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI145693105, Length=233, Percent_Identity=22.3175965665236, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787530, Length=235, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081904, Length=199, Percent_Identity=27.1356783919598, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=282, Percent_Identity=26.5957446808511, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788296, Length=236, Percent_Identity=27.1186440677966, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34954; Mature: 34954

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLSLSSLSASVPMSSYRILQETAVRYFLEVVRTGSVKDAALKLNVAPSAVSRQIAKLE
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
SELDTLLFDRRARGLVPNAAGELLAAFAKRSLQDIERVTGDIQALRGLRAGRVRLASVEG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEEHHHH
IAHEFLPTLAARFREQHTGIRFDLDVCLQGDVARRIRDGEADIGVTLSGLPEREIEVELR
HHHHHHHHHHHHHHHHHCCEEEEEEEEECCHHHHHHCCCCCCCCEEECCCCCCCEEEEEE
HPAPVLAIMAPDHPLAGQRQVSLSQVIAYPLALPPKGSSLRQLLDTSCSRQDLHYQTVFS
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEHHC
SNHLDALVSFVVAGGGAISFYGELSIRGRLESGTIAAVPLRDREMNERYIEIQTLAKRSL
CCHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCC
PPAARAFVQQLVQTITGVGTA
CHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDRLSLSSLSASVPMSSYRILQETAVRYFLEVVRTGSVKDAALKLNVAPSAVSRQIAKLE
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
SELDTLLFDRRARGLVPNAAGELLAAFAKRSLQDIERVTGDIQALRGLRAGRVRLASVEG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEEHHHH
IAHEFLPTLAARFREQHTGIRFDLDVCLQGDVARRIRDGEADIGVTLSGLPEREIEVELR
HHHHHHHHHHHHHHHHHCCEEEEEEEEECCHHHHHHCCCCCCCCEEECCCCCCCEEEEEE
HPAPVLAIMAPDHPLAGQRQVSLSQVIAYPLALPPKGSSLRQLLDTSCSRQDLHYQTVFS
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEHHC
SNHLDALVSFVVAGGGAISFYGELSIRGRLESGTIAAVPLRDREMNERYIEIQTLAKRSL
CCHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCC
PPAARAFVQQLVQTITGVGTA
CHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]